Lipase-catalyzed esterification of glycerol and polyunsaturated fatty acids from fish and microalgae oils

Progress in Industrial Microbiology

Volumn 35, Issue C, 1999, Pages 379-391

  Robles Medina, A ^a   Esteban Cerdan L ^a   Gimenez Gimenez A ^a   Camacho Paez B ^a   Ibanez Gonzalez M J ^a   Molina Grima, E ^a  

^a UNIVERSITY OF ALMERÍA   (Spain)

Author keywords

Fish oil; Lipase catalyzed esterification; Microalga oils; Polyunsaturated fatty acids; Triglycerides

Indexed keywords

EID: 77957095586     PISSN: 00796352     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0079-6352(99)80131-3     Document Type: Article

References (35)

1. Acién Fernández F.G., García Camacho F., Sánchez Pérez J.A., Fernández Sevilla J.M., and Molina Grima E. Modeling of biomass productivity in tubular photobioreactors for microalgal cultures: effects of dilution rate, tube diameter and solar irradiance. Biotech. Bioeng. 58 (1998) 605-614
2. Boswell K., Koskelo E.-K., Carl L., Glaza S., Hensen D.J., Williams K.D., and Kyle D.J. Preclinical evaluation of single-cell oils that are highly enriched with arachidonic acid and docosahexaenoic acid. Food Chem. Toxicol. 34 (1996) 585-593
3. Braden L.M., and Carroll K.K. Dietary polyunsaturated fat in relation to mammary carcinogenesis in rats. Lipids 21 (1986) 285-288
4. Camacho Rubio F., Acién Fernández F.G., Sánchez Pérez J.A., García Camacho F., and Molina Grima E. Prediction of dissolved oxygen and carbon dioxide concentration profiles in tubular photobioreactors for microalgal culture. Biotech. Bioeng. 62 (1999) 71-86
5. Cartens M., Molina Grima E., Robles Medina A., Giménez Giménez A., and Ibáñez González M.J. Eicosapentaenoic acid (20:5n-3) from the marine microalga Phaeodacotylum tricornutum. J. Am. Oil Chem. Soc. 73 (1996) 1025-1031
6. Dordick J.S. Enzymatic catalysis in monophasic organic solvents. Enzyme Microb. Technol. 11 (1989) 194-211
7. ™ IM-20. Biotechnol. Lett. 10 (1988) 629-634
8. Ergan F., Trani M., and André G. Production of glycerides from glycerol and fatty acid by immobilized lipases in non-aqueous media. Biotech. Bioeng. 35 (1990) 195-200
9. Esteban Cerdán L., Robles Medina A., Giménez Giménez A., Ibáñez González M.J., and Molina Grima E. Synthesis of PUFA enriched triglycerides by lipase catalyzed esterification. J. Am. Oil Chem. Soc. 75 (1998) 1329-1337
10. Giménez Giménez A., Ibáñez González M.J., Robles Medina A., Molina Grima E., García Salas S., and Esteban Cerdán L. Downstream processing and purification of eicosapentaenoic (20:5n-3) and arachidonic acids (20:4n-6) from the microalga Porphyridium cruentum. Bioseparation 7 (1998) 89-99
11. 3. Biochem. Biophys. Res. Comm. 151 (1988) 1386-1394
12. Innis S.M. Essential fatty acids in growth and development. Prog. Lipid Res. 30 (1991) 39-103
13. Koletzko B., Decsi T., and Demmelmair H. Arachidonic acid supply and metabolism in human infants born at full term. Lipids 31 (1996) 79-83
14. Koletzko B., Schmidt E., Bremer H.J., Haung M., and Harzer G. Effects of dietary long-chain polyunsaturated fatty acids on the essential fatty acid status of premature infants. Eur. J. Pediatr. 148 (1989) 669-675
15. Kosugi Y., and Azuma N. Synthesis of triacylglycerol from polyunsaturated fatty acid by immobilized lipase. J. Am. Oil Chem. Soc. 71 (1994) 1397-1403
16. Leaf A., and Kang J.X. Cardiac arrhythmia. Abstract of International Conference on Highly Unsaturated Fatty Acids in Nutrition and Disease Prevention. Barcelona (1996) 41
17. Lepage G., and Roy C. Improved recovery of fatty acid through direct transesterification without prior extraction or purification. J. Lipid Res. 25 (1984) 1391-1396
18. Luck T., Kiesser T., and Bauer W. In: Applewhite T.H. (Ed). Proceeding of the world conference on Biotechnology for the fats and oils industry (1988), American Oil Chemists Society, Champaign, IL 343-345
19. Miller D.A., Prausnitz J.M., and Blanch H.W. Kinetic of lipase-catalised interesterification of triglycerides in cyclohexane. Enzyme Microb. Technol. 13 (1991) 98-103
20. Molina Grima E., Robles Medina A., Giménez Giménez A., Sánchez Pérez J.A., García Camacho F., and Garcia Sánchez J.L. Comparison between extraction of lipids and fatty acids from microalgal biomass. J. Am. Oil Chem. Soc. 71 (1994) 955-959
21. Molina Grima E., Robles Medina A., Giménez Giménez A., and Ibáñez González M.J. Gram-scale purification of eicosapentaenoic acid (EPA 20:5n-3) from wet Phaeodactylum tricornutum UTEX 640 biomass. J. Appl. Phycol. 8 (1996) 359-367
22. Nichols B.W., and Appleby R.S. The distribution and biosynthesis of arachidonic acid in algae. Phytochemistry 8 (1969) 1907-1915
23. Osada K., Takahashi K., and Hatano M. Polyunsaturated fatty glyceride synthesis by microbial lipases. J. Am. Oil Chem. Soc. 67 (1990) 921-922
24. Rambjor G.S., Walen A.I., Windsor S.L., and Harris W.S. Eicosapentaenoic acid is primarily responsible for hypotriglyceridemic effect of fish oil in humans. Lipids 31 Suppl. S (1996) 45-49
25. Robles Medina A., Giménez Giménez A., García Camacho F., Sánchez Pérez J.A., Molina Grima E., and Contreras Gómez A. Concentration and purification of stearidonic, eicosapentaenoic and docosahexaenoic acids from cod liver oil and the marine microalga Isochrysis galbana. J. Am. Oil Chem. Soc. 72 (1995) 575-583
26. Shimizu S., Shinmen Y., Kawashima H., Akimoto K., and Yamada H. Production of C-20 polyunsaturated fatty acids by fungi. Proceeding of World Conference on Biotechnology for the Fats and Oils Industry (1987), AOCS, Champaign, IL 1000-1006
27. Shinmen Y., Shimizu S., Akimoto D., Kawashima, H., Yamada, and H. Production of arachidonic acid by Mortierella fungi. Selection of a potent producer and optimization of culture conditions for large-scale production. Appl. Microbiol. Biotechnol. 31 (1989) 11-16
28. Simopoulos A.P. Omega-3 fatty acids in health and disease and in growth and development. Am. J. Clin. Nutr. 54 (1991) 438-463
29. Sing M.D., and Chandra M.D. Biochemical and cellular effects of fish and fish oils. Prog. Food Nutr. Sci. 12 (1988) 371-419
30. Weylandt K.H., Kang J.X., and Leaf A. Polyunsaturated fatty acids exert antiarrhythmic actions as free acids rather than in phospholipids. Lipids 31 (1996) 977-982
31. WHO FAO. Dietary fats and oils in human nutrition. Report of an expert consultation (1977), FAO, Rome, Italy
32. Wigmore S.J., Ross J.A., Falconer J.S., Plester C.E., Tisdade M.J., Carter D.C., and Faron K.C.H. Effect of PUFA on the progress of cachexia in patiens with pancreatic cancer. Nutrition 12 (1996) 27-30
33. Yongmanitchai W., and Ward O.P. Screening of algae for potential alternative sources of eicosapentaenoic acid. Phytochemistry 30 (1991) 2963-2967
34. Zaks A., and Klibanov A. Enzyme-catalyzed processes inorganic solvents. Biochemistry 82 (1985) 3192-3196
35. Ziboh V.A. ω3 polyunsaturated fatty acid constituents of fish oil and the management of skin inflammatory and scaly disorders. In: Simopoulos A.P., Kifer R.R., Martin R.E., and Barlow S.M. (Eds). Health Effects of ω3 Polyunsaturated Fatty Acids in Seafoods. Word Rev. Nutr. Diet. 66 (1991) 425-435