Dysregulation of the IL-13 receptor system: A novel pathomechanism in pulmonary arterial hypertension

American Journal of Respiratory and Critical Care Medicine

Volumn 182, Issue 6, 2010, Pages 805-818

  Hecker, Matthias ^a   Zasłona, Zbigniew ^a   Kwapiszewska, Grazyna ^a   Niess, Gero ^a   Zakrzewicz, Anna ^a   Hergenreider, Eduard ^a   Wilhelm, Jochen ^a   Marsh, Leigh M ^a   Sedding, Daniel ^b   Klepetko, Walter ^c   Lohmeyer, Jürgen ^a   Dimmeler, Stefanie ^a   Seeger, Werner ^a   Weissmann, Norbert ^a   Schermuly, Ralph T ^a   Kneidinger, Nikolaus ^a   Eickelberg, Oliver ^d   Morty, Rory E ^a  

^a JUSTUS LIEBIG UNIVERSITY GIESSEN   (Germany)

^b GOETHE UNIVERSITY   (Germany)

^c UNIVERSITY OF VIENNA   (Austria)

^d INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

Endothelin; Interleukin; Pulmonary arterial hypertension; Smooth muscle

Indexed keywords

E 5531; ENDOTHELIN 1; INTERLEUKIN 13; INTERLEUKIN 13 RECEPTOR; INTERLEUKIN 13 RECEPTOR ALPHA1; INTERLEUKIN 4 RECEPTOR; MONOCROTALINE; SMALL INTERFERING RNA; STAT3 PROTEIN; STAT6 PROTEIN; INTERLEUKIN 13 RECEPTOR ALPHA2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL HYPERPLASIA; CELL PROLIFERATION; CONTROLLED STUDY; FLOW CYTOMETRY; GENE CONTROL; GENE REPRESSION; GENE SILENCING; HUMAN; HUMAN TISSUE; HYPOXIA; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; LASER CAPTURE MICRODISSECTION; MOUSE; NONHUMAN; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PULMONARY HYPERTENSION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; UPREGULATION; ADOLESCENT; ADULT; ANIMAL; DISEASE MODEL; FEMALE; LUNG; MALE; METABOLISM; MIDDLE AGED; PHYSIOLOGY; PULMONARY ARTERY; RAT; VASCULAR SMOOTH MUSCLE;

ADOLESCENT; ADULT; ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; FLOW CYTOMETRY; HUMANS; HYPERTENSION, PULMONARY; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-13; INTERLEUKIN-13 RECEPTOR ALPHA1 SUBUNIT; INTERLEUKIN-13 RECEPTOR ALPHA2 SUBUNIT; LUNG; MALE; MICE; MIDDLE AGED; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PULMONARY ARTERY; RATS; RECEPTORS, INTERLEUKIN-13; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; UP-REGULATION; YOUNG ADULT;

EID: 77957035915     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200909-1367OC     Document Type: Article

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