Characterization of side population cells in human malignant mesothelioma cell lines

Lung Cancer

Volumn 70, Issue 2, 2010, Pages 146-151

  Kai, Kiyonori ^a,b   D'Costa, Susan ^a   Yoon, Byung Il ^a,c   Brody, Arnold R ^a   Sills, Robert C ^d   Kim, Y ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b DAIICHI SANKYO CO   (Japan)

^c Kangwon National University   (South Korea)

^d NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Cancer stem cell; Flow cytometry; Hoechst 33342; Mesothelioma; Side population; Tumorigenicity

Indexed keywords

CISPLATIN;

ANIMAL EXPERIMENT; ARTICLE; ASSAY; CARCINOGENICITY; CELL FRACTIONATION; CELL MEMBRANE POTENTIAL; CELL PROLIFERATION; CLONOGENESIS; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; MALIGNANT MESOTHELIOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIDE POPULATION ASSAY; STEM CELL; TUMOR CELL;

ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SEPARATION; CISPLATIN; FEASIBILITY STUDIES; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MESOTHELIOMA; MICE; MICE, SCID; NEOPLASM TRANSPLANTATION; NEOPLASTIC STEM CELLS; SIDE-POPULATION CELLS;

EID: 77957017533     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2010.04.020     Document Type: Article

References (23)

1. Carbone M., Kratzke R.A., Testa J.R. The pathogenesis of mesothelioma. Semin Oncol 2002, 29:2-17.
2. La Vecchia C., Decarli A., Peto J., Levi F., Tomei F., Negri E. An age, period and cohort analysis of pleural cancer mortality in Europe. Eur J Cancer Prev 2000, 9:179-184.
3. Price B., Ware A. Mesothelioma trends in the United States: an update based on surveillance, epidemiology, and end results program data for 1973 through 2003. Am J Epidemiol 2004, 159:107-112.
4. Lobo N.A., Shimono Y., Qian D., Clarke M.F. The biology of cancer stem cells. Annu Rev Cell Dev Biol 2007, 23:675-699.
5. Reya T., Morrison S.J., Clarke M.F., Weissman I.L. Stem cells, cancer, and cancer stem cells. Nature 2001, 414:105-111.
6. Bjerkvig R., Tysnes B.B., Aboody K.S., Najbauer J., Terzis A.J. Opinion: the origin of the cancer stem cell: current controversies and new insights. Nat Rev Cancer 2005, 5:899-904.
7. Dean M., Fojo T., Bates S. Tumour stem cells and drug resistance. Nat Rev Cancer 2005, 5:275-284.
8. Wu C., Alman B.A. Side population cells in human cancers. Cancer Lett 2008, 268:1-9.
9. Goodell M.A., Brose K., Paradis G., Conner A.S., Mulligan R.C. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med 1996, 183:1797-1806.
10. Kim Y., Ton T.V., DeAngelo A.B., Morgan K., Devereux T.R., Anna C., et al. Major carcinogenic pathways identified by gene expression analysis of peritoneal mesotheliomas following chemical treatment in F344 rats. Toxicol Appl Pharmacol 2006, 214:144-151.
11. Al-Hajj M., Wicha M.S., Benito-Hernandez A., Morrison S.J., Clarke M.F. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 2003, 100:3983-3988.
12. Kelly P.N., Dakic A., Adams J.M., Nutt S.L., Strasser A. Tumor growth need not be driven by rare cancer stem cells. Science 2007, 317:337.
13. Zheng X., Shen G., Yang X., Liu W. Most C6 cells are cancer stem cells: evidence from clonal and population analyses. Cancer Res 2007, 67:3691-3697.
14. Ho M.M., Ng A.V., Lam S., Hung J.Y. Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells. Cancer Res 2007, 67:4827-4833.
15. Wang J., Guo L.P., Chen L.Z., Zeng Y.X., Lu S.H. Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line. Cancer Res 2007, 67:3716-3724.
16. Kim M., Turnquist H., Jackson J., Sgagias M., Yan Y., Gong M., et al. The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells. Clin Cancer Res 2002, 8:22-28.
17. Sarkadi B., Homolya L., Szakacs G., Varadi A. Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system. Physiol Rev 2006, 86:1179-1236.
18. Trosko J.E. From adult stem cells to cancer stem cells: Oct-4 Gene, cell-cell communication, and hormones during tumor promotion. Ann N Y Acad Sci 2006, 1089:36-58.
19. Maliekal T.T., Bajaj J., Giri V., Subramanyam D., Krishna S. The role of Notch signaling in human cervical cancer: implications for solid tumors. Oncogene 2008, 27:5110-5114.
20. Patrawala L., Calhoun T., Schneider-Broussard R., Zhou J., Claypool K., Tang D.G. Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic. Cancer Res 2005, 65:6207-6219.
21. Vivanco I., Sawyers C.L. The phosphatidylinositol 3-kinase AKT pathway in human cancer. Nat Rev Cancer 2002, 2:489-501.
22. Zhou J., Wulfkuhle J., Zhang H., Gu P., Yang Y., Deng J., et al. Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance. Proc Natl Acad Sci USA 2007, 104:16158-16163.
23. Androutsellis-Theotokis A., Leker R.R., Soldner F., Hoeppner D.J., Ravin R., Poser S.W., et al. Notch signalling regulates stem cell numbers in vitro and in vivo. Nature 2006, 442:823-826.