메뉴 건너뛰기




Volumn 39, Issue , 2008, Pages 409-429

Nuclear receptors as targets in cardiovascular diseases

Author keywords

Heart failure; Mineralocorticoid receptor; Peroxisome proliferator activated receptor ; Thyroid hormone receptors

Indexed keywords

CYTOLOGY;

EID: 77956929370     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9783527623297.ch13     Document Type: Chapter
Times cited : (3)

References (94)
  • 1
    • 0035120424 scopus 로고    scopus 로고
    • A review of the medical treatment of primary aldosteronism
    • Lim, P.O., Young, W.F. and MacDonald, T.M. (2001) A review of the medical treatment of primary aldosteronism. Journal of Hypertension, 19, 353-361.
    • (2001) Journal of Hypertension , vol.19 , pp. 353-361
    • Lim, P.O.1    Young, W.F.2    MacDonald, T.M.3
  • 4
    • 0036793584 scopus 로고    scopus 로고
    • High prevalence of primary aldosteronism using postcaptopril plasma aldosterone to renin ratio as a screening test among Italian hypertensives
    • Rossi, E., Regolisti, G., Negro, A., Sani, C., Davoli, S. and Perazzoli, F. (2002) High prevalence of primary aldosteronism using postcaptopril plasma aldosterone to renin ratio as a screening test among Italian hypertensives. American Journal of Hypertension, 15, 896-902.
    • (2002) American Journal of Hypertension , vol.15 , pp. 896-902
    • Rossi, E.1    Regolisti, G.2    Negro, A.3    Sani, C.4    Davoli, S.5    Perazzoli, F.6
  • 5
    • 0000167622 scopus 로고
    • Action of new steroids in blocking effects of aldosterone and desoxycorticosterone on salt
    • Kagawa, C.M., Cella, J.A. and Van Arman, C.G. (1957) Action of new steroids in blocking effects of aldosterone and desoxycorticosterone on salt. Science, 126, 1015-1016.
    • (1957) Science , vol.126 , pp. 1015-1016
    • Kagawa, C.M.1    Cella, J.A.2    Van Arman, C.G.3
  • 6
    • 37049252880 scopus 로고
    • Sodium diuresis induced by steroidal antagonists of aldosterone
    • Liddle, G.W. (1957) Sodium diuresis induced by steroidal antagonists of aldosterone. Science, 126, 1016-1018.
    • (1957) Science , vol.126 , pp. 1016-1018
    • Liddle, G.W.1
  • 7
    • 1842305967 scopus 로고
    • Gynecomastia during therapy with spironolactone
    • Mann, N. (1963) Gynecomastia during therapy with spironolactone. Journal of the American Medical Association, 184, 778-780.
    • (1963) Journal of the American Medical Association , vol.184 , pp. 778-780
    • Mann, N.1
  • 17
    • 0033517302 scopus 로고    scopus 로고
    • The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Rand omized Aldactone Evaluation Study Investigators
    • Pitt, B., Zannad, F., Remme, W.J., Cody, R., Castaigne, A., Perez, A., Palensky, J. and Wittes, J. (1999) The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Rand omized Aldactone Evaluation Study Investigators. New England Journal of Medicine, 341, 709-717.
    • (1999) New England Journal of Medicine , vol.341 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme, W.J.3    Cody, R.4    Castaigne, A.5    Perez, A.6    Palensky, J.7    Wittes, J.8
  • 18
    • 0037417252 scopus 로고    scopus 로고
    • Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study Investigators. Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction
    • Pitt, B., Remme, W., Zannad, F., Neaton, J., Martinez, F., Roniker, B., Bittman, R., Hurley, S. et al. (2003) Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study Investigators. Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction. New England Journal of Medicine, 348, 1309-1321.
    • (2003) New England Journal of Medicine , vol.348 , pp. 1309-1321
    • Pitt, B.1    Remme, W.2    Zannad, F.3    Neaton, J.4    Martinez, F.5    Roniker, B.6    Bittman, R.7    Hurley, S.8
  • 19
    • 20544453277 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and treatment of chronic heart failure: executive summary (update 2005): the Task Force for the Diagnosis and Treatment of Chronic Heart Failure of the European Society of Cardiology
    • Swedberg, K., Cleland, J., Dargie, H., Drexler, H., Follath, F., Komajda, M., Tavazzi, L., Smiseth, O.A. et al. (2005) Guidelines for the diagnosis and treatment of chronic heart failure: executive summary (update 2005): the Task Force for the Diagnosis and Treatment of Chronic Heart Failure of the European Society of Cardiology. European Heart Journal, 26, 1115-1140.
    • (2005) European Heart Journal , vol.26 , pp. 1115-1140
    • Swedberg, K.1    Cleland, J.2    Dargie, H.3    Drexler, H.4    Follath, F.5    Komajda, M.6    Tavazzi, L.7    Smiseth, O.A.8
  • 20
    • 33748637106 scopus 로고    scopus 로고
    • Mineralocorticoidreceptor blockade, hypertension and heart failure
    • Funder, J. (2005) Mineralocorticoidreceptor blockade, hypertension and heart failure. Nature Clinical Practice Endocrinology & Metabolism, 1, 4-5.
    • (2005) Nature Clinical Practice Endocrinology & Metabolism , vol.1 , pp. 4-5
    • Funder, J.1
  • 21
    • 85019807199 scopus 로고    scopus 로고
    • WO 2005/066161
    • Eli Lilly & Co., WO 2005/066161.
  • 22
    • 85019802300 scopus 로고    scopus 로고
    • WO 2004/052847
    • Eli Lilly & Co., WO 2004/052847.
  • 23
    • 85019812474 scopus 로고    scopus 로고
    • WO 2004/067529
    • Eli Lilly & Co., WO 2004/067529.
  • 24
    • 85019794979 scopus 로고    scopus 로고
    • WO 2003/078394
    • Eli Lilly & Co., WO 2003/078394.
  • 26
    • 85019826381 scopus 로고    scopus 로고
    • WO 2006/076202
    • Exelixis, Inc., WO 2006/076202.
  • 27
    • 85019826401 scopus 로고    scopus 로고
    • WO 2006/012642
    • Exelixis, Inc., WO 2006/012642.
  • 28
    • 85019792470 scopus 로고    scopus 로고
    • WO 2006/077821
    • Dainippon Sumitomo Pharma Co., Ltd, WO 2006/077821.
  • 29
    • 85019793878 scopus 로고    scopus 로고
    • WO 2006/010142
    • Ligand Pharmaceuticals, Inc., WO 2006/010142.
  • 30
    • 85019774321 scopus 로고    scopus 로고
    • WO 2005/087740
    • Bayer HealthCare AG, WO 2005/087740.
  • 31
    • 85019812666 scopus 로고    scopus 로고
    • WO 2006/066011
    • IRM LLC, WO 2006/066011.
  • 32
    • 85019774290 scopus 로고    scopus 로고
    • WO2005/097118
    • Takeda Pharmaceutical Co. Ltd, WO2005/097118.
  • 33
  • 34
    • 85019807265 scopus 로고    scopus 로고
    • Pharmacological characterization of a mutant mineralocorticoid receptor responsible for severe, early-onset hypertension
    • Kolkhof, P., Jilg, V. and Schäfer, S. (2007) Pharmacological characterization of a mutant mineralocorticoid receptor responsible for severe, early-onset hypertension. Clinical Research in Cardiology, 96 (Suppl 1). P525.
    • (2007) Clinical Research in Cardiology , vol.96 , pp. P525
    • Kolkhof, P.1    Jilg, V.2    Schäfer, S.3
  • 36
    • 0032733715 scopus 로고    scopus 로고
    • Organ specific expression of thyroid hormone receptor mRNA and protein in different human tissues
    • Shahrara, S., Drvota, V. and Sylven, C. (1999) Organ specific expression of thyroid hormone receptor mRNA and protein in different human tissues. Biological & Pharmaceutical Bulletin, 22, 1027-1033.
    • (1999) Biological & Pharmaceutical Bulletin , vol.22 , pp. 1027-1033
    • Shahrara, S.1    Drvota, V.2    Sylven, C.3
  • 37
    • 17744387900 scopus 로고    scopus 로고
    • The thyroid hormone receptor-β-selective agonist GC-1 differentially affects plasma lipids and cardiac activity
    • Trost, S.U., Swanson, E., Gloss, B., Wang-Iverson, D.B., Zhang, H., Volodarsky, T., Grover, G.J., Baxter, J.D. et al. (2000) The thyroid hormone receptor-β-selective agonist GC-1 differentially affects plasma lipids and cardiac activity. Endocrinology, 141, 3057-3064.
    • (2000) Endocrinology , vol.141 , pp. 3057-3064
    • Trost, S.U.1    Swanson, E.2    Gloss, B.3    Wang-Iverson, D.B.4    Zhang, H.5    Volodarsky, T.6    Grover, G.J.7    Baxter, J.D.8
  • 40
    • 0033578662 scopus 로고    scopus 로고
    • Thyroid hormone regulates hyperpolarization-activated cyclic nucleotide-gated channel (HCN2) mRNA in the rat heart
    • Pachucki, J., Burmeister, L.A. and Larsen, P.R. (1999) Thyroid hormone regulates hyperpolarization-activated cyclic nucleotide-gated channel (HCN2) mRNA in the rat heart. Circulation Research, 85, 498-503.
    • (1999) Circulation Research , vol.85 , pp. 498-503
    • Pachucki, J.1    Burmeister, L.A.2    Larsen, P.R.3
  • 41
    • 0035163169 scopus 로고    scopus 로고
    • Mechanism of thyroid-hormone regulated expression of the SERCA genes in skeletal muscle:implications for thermogenesis
    • Simonides, W.S., Thelen, M.H.M., Van der Linden, C.G., Muller, A. and Van Hardeveld, C. (2001) Mechanism of thyroid-hormone regulated expression of the SERCA genes in skeletal muscle:implications for thermogenesis. Bioscience Reports, 21, 139-154.
    • (2001) Bioscience Reports , vol.21 , pp. 139-154
    • Simonides, W.S.1    Thelen, M.H.M.2    van der Linden, C.G.3    Muller, A.4    Van Hardeveld, C.5
  • 42
    • 17744396662 scopus 로고    scopus 로고
    • Cardiac ion channel expression and contractile function in mice with deletion of thyroid hormone receptor α or β
    • Gloss, B., Trost, S., Bluhm, W., Swanson, E., Clark, R., Winkfein, R., Janzen, K., Giles, W. et al. (2001) Cardiac ion channel expression and contractile function in mice with deletion of thyroid hormone receptor α or β. Endocrinology, 142, 544-550.
    • (2001) Endocrinology , vol.142 , pp. 544-550
    • Gloss, B.1    Trost, S.2    Bluhm, W.3    Swanson, E.4    Clark, R.5    Winkfein, R.6    Janzen, K.7    Giles, W.8
  • 50
    • 13544259661 scopus 로고    scopus 로고
    • Dronedarone administration prevents body weight gain and increases tolerance of the heart to ischemic stress: a possible involvement of thyroid hormone receptor α1
    • Pantos, C., Mourouzis, I., Malliopoulou, V., Paizis, I., Tzeis, S., Moraitis, P., Sfakianoudis, K., Varonos, D.D. et al. (2005) Dronedarone administration prevents body weight gain and increases tolerance of the heart to ischemic stress: a possible involvement of thyroid hormone receptor α1. Thyroid, 15, 16-23.
    • (2005) Thyroid , vol.15 , pp. 16-23
    • Pantos, C.1    Mourouzis, I.2    Malliopoulou, V.3    Paizis, I.4    Tzeis, S.5    Moraitis, P.6    Sfakianoudis, K.7    Varonos, D.D.8
  • 51
    • 4644300656 scopus 로고    scopus 로고
    • Regulation of gene expression in cardiomyocytes by thyroid hormone and thyroid hormone analogs 3,5-diiodothyropropionic acid and CGS 23425 [N-[3,5-dimethyl-4-(4'-hydroxy-3'-isopropylphenoxy)-phenyl]-oxamic acid]
    • Adamson, C., Maitra, N., Bahl, J., Greer, K., Klewer, S., Hoying, J. and Morkin, E. (2004) Regulation of gene expression in cardiomyocytes by thyroid hormone and thyroid hormone analogs 3,5-diiodothyropropionic acid and CGS 23425 [N-[3,5-dimethyl-4-(4'-hydroxy-3'-isopropylphenoxy)-phenyl]-oxamic acid]. Journal of Pharmacology and Experimental Therapeutics, 311, 164-171.
    • (2004) Journal of Pharmacology and Experimental Therapeutics , vol.311 , pp. 164-171
    • Adamson, C.1    Maitra, N.2    Bahl, J.3    Greer, K.4    Klewer, S.5    Hoying, J.6    Morkin, E.7
  • 53
  • 56
    • 0034119373 scopus 로고    scopus 로고
    • Mechanism of liver-selective thyromimetic activity of SK&F L-94901: evidence for the presence of a cell-type-specific nuclear iodothyronine transport process
    • Ichikawa, K., Miyamoto, T., Kakizawa, T., Suzuki, S., Kaneko, A., Mori, J., Hara, M., Kumagai, M. et al. (2000) Mechanism of liver-selective thyromimetic activity of SK&F L-94901: evidence for the presence of a cell-type-specific nuclear iodothyronine transport process. Journal of Endocrinology, 165, 391-397.
    • (2000) Journal of Endocrinology , vol.165 , pp. 391-397
    • Ichikawa, K.1    Miyamoto, T.2    Kakizawa, T.3    Suzuki, S.4    Kaneko, A.5    Mori, J.6    Hara, M.7    Kumagai, M.8
  • 57
    • 85019784975 scopus 로고    scopus 로고
    • EP 1471049A1
    • Kissei Pharmaceutical Co., Ltd, EP 1471049A1, (2004).
    • (2004)
  • 58
    • 14844328065 scopus 로고    scopus 로고
    • Different inhibitory effects in the early and late phase of treatment with KAT-681, a liver-selective thyromimetic, on rat hepatocarcinogenesis induced by 2-acetylaminofluorene and partial hepatectomy after diethylnitrosamine initiation
    • Hayashi, M., Tamura, T., Kuroda, J., Ohnota, H., Shibata, N., Akahane, M., Kashida, Y. and Mitsumori, K. (2005) Different inhibitory effects in the early and late phase of treatment with KAT-681, a liver-selective thyromimetic, on rat hepatocarcinogenesis induced by 2-acetylaminofluorene and partial hepatectomy after diethylnitrosamine initiation. Toxicological Sciences, 84, 22-28.
    • (2005) Toxicological Sciences , vol.84 , pp. 22-28
    • Hayashi, M.1    Tamura, T.2    Kuroda, J.3    Ohnota, H.4    Shibata, N.5    Akahane, M.6    Kashida, Y.7    Mitsumori, K.8
  • 59
    • 0025132245 scopus 로고
    • Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
    • Issemann, I. and Green, S. (1990) Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature, 347, 645-650.
    • (1990) Nature , vol.347 , pp. 645-650
    • Issemann, I.1    Green, S.2
  • 60
    • 0020521863 scopus 로고
    • Evaluation of selected hypolipidemic agents for the induction of peroxisomal enzymes and peroxisome proliferation in the rat liver
    • Lalwani, N.D., Reddy, M.K., Qureshi, S.A., Sirtori, C.R., Abiko, Y. and Reddy, J.K. (1983) Evaluation of selected hypolipidemic agents for the induction of peroxisomal enzymes and peroxisome proliferation in the rat liver. Human Toxicology, 2, 27-48.
    • (1983) Human Toxicology , vol.2 , pp. 27-48
    • Lalwani, N.D.1    Reddy, M.K.2    Qureshi, S.A.3    Sirtori, C.R.4    Abiko, Y.5    Reddy, J.K.6
  • 61
    • 0038637806 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor α is downregulated in the failing human heart
    • Karbowska, J., Kochan, Z. and Smolenski, R.T. (2003) Peroxisome proliferator-activated receptor α is downregulated in the failing human heart. Cellular& MolecularBiologyLetters, 8, 49-53.
    • (2003) Cellular& MolecularBiologyLetters , vol.8 , pp. 49-53
    • Karbowska, J.1    Kochan, Z.2    Smolenski, R.T.3
  • 65
    • 0033793133 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation
    • Chinetti, G., Fruchart, J.C. and Staels, B. (2000) Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation. Inflammation Research, 49, 497-505.
    • (2000) Inflammation Research , vol.49 , pp. 497-505
    • Chinetti, G.1    Fruchart, J.C.2    Staels, B.3
  • 67
    • 1942484870 scopus 로고    scopus 로고
    • Myocardial fibrosis and diastolic dysfunction in deoxycorticosterone acetate-salt hypertensive rats is ameliorated by the peroxisome proliferator-activated receptor-α activator fenofibrate, partly by suppressing inflammatory responses associated with the nuclear factor-kB pathway
    • Ogata, T., Miyauchi, T., Sakai, S., Takanashi, M., Irukayama-Tomobe, Y. and Yamaguchi, I. (2004) Myocardial fibrosis and diastolic dysfunction in deoxycorticosterone acetate-salt hypertensive rats is ameliorated by the peroxisome proliferator-activated receptor-α activator fenofibrate, partly by suppressing inflammatory responses associated with the nuclear factor-kB pathway. Journal of the American College of Cardiology, 43, 1481-1488.
    • (2004) Journal of the American College of Cardiology , vol.43 , pp. 1481-1488
    • Ogata, T.1    Miyauchi, T.2    Sakai, S.3    Takanashi, M.4    Irukayama-Tomobe, Y.5    Yamaguchi, I.6
  • 68
    • 85019826250 scopus 로고    scopus 로고
    • Activation of PPAR-α reduces cardiac and renal end-organ damage in salt sensitive hypertension
    • Sandner, P., Klein, M., Albrecht, B., Hartmann, E., Schäfer, S. and Hütter, J. (2006) Activation of PPAR-α reduces cardiac and renal end-organ damage in salt sensitive hypertension. European Heart Journal, 27 (Suppl 1), 2925.
    • (2006) European Heart Journal , vol.27 , pp. 2925
    • Sandner, P.1    Klein, M.2    Albrecht, B.3    Hartmann, E.4    Schäfer, S.5    Hütter, J.6
  • 69
    • 85019826271 scopus 로고    scopus 로고
    • Activation of peroxisome proliferatoractivated receptor-α (PPARα) ameliorates post myocardial infarction heart failure in the rat: prevention of cardiac remodeling
    • Albrecht, B., Klein, M., Sandner, P., Golz, S., Hütter, J. and Schäfer, S. (2006) Activation of peroxisome proliferatoractivated receptor-α (PPARα) ameliorates post myocardial infarction heart failure in the rat: prevention of cardiac remodeling. European Heart Journal, 27 (Suppl 1), 437.
    • (2006) European Heart Journal , vol.27 , pp. 437
    • Albrecht, B.1    Klein, M.2    Sandner, P.3    Golz, S.4    Hütter, J.5    Schäfer, S.6
  • 71
    • 34250212715 scopus 로고    scopus 로고
    • Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
    • Nissen, S.E. and Wolski, K. (2007) Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. New England Journal of Medicine, 356, 2457-2471.
    • (2007) New England Journal of Medicine , vol.356 , pp. 2457-2471
    • Nissen, S.E.1    Wolski, K.2
  • 72
    • 34147138210 scopus 로고    scopus 로고
    • Drug evaluation: K-111, an insulin-sensitizing peroxisome proliferators activated receptor α agonist
    • Drew, B.G. and Calkin, A.C. (2007) Drug evaluation: K-111, an insulin-sensitizing peroxisome proliferators activated receptor α agonist. Current Opinion in Investigational Drugs, 8, 324-330.
    • (2007) Current Opinion in Investigational Drugs , vol.8 , pp. 324-330
    • Drew, B.G.1    Calkin, A.C.2
  • 74
    • 50749101387 scopus 로고
    • An experimental investigation on rickets
    • Mellanby, E. (1919) An experimental investigation on rickets. Lancet, 1, 407-412.
    • (1919) Lancet , vol.1 , pp. 407-412
    • Mellanby, E.1
  • 76
    • 0024587532 scopus 로고
    • Vitamin D is related to blood pressure and other cardiovascular risk factors in middle-aged men
    • Lind, L., Wengle, B., Wide, L. and Ljunghall, S. (1989) Vitamin D is related to blood pressure and other cardiovascular risk factors in middle-aged men. American Journal of Hypertension, 2, 20-25.
    • (1989) American Journal of Hypertension , vol.2 , pp. 20-25
    • Lind, L.1    Wengle, B.2    Wide, L.3    Ljunghall, S.4
  • 89
    • 0037432165 scopus 로고    scopus 로고
    • T-0901317, a synthetic liver X receptor ligand, inhibits development of atherosclerosis in LDL receptor-deficient mice
    • Terasaka, N., Hiroshima, A., Koieyama, T., Ubukata, N., Morikawa, Y., Nakai, D. and Inaba, T. (2003) T-0901317, a synthetic liver X receptor ligand, inhibits development of atherosclerosis in LDL receptor-deficient mice. FEBS Letters, 536, 6-11.
    • (2003) FEBS Letters , vol.536 , pp. 6-11
    • Terasaka, N.1    Hiroshima, A.2    Koieyama, T.3    Ubukata, N.4    Morikawa, Y.5    Nakai, D.6    Inaba, T.7
  • 91
    • 34247139296 scopus 로고    scopus 로고
    • Selective upregulation of LXR-regulated genes ABCA1, ABCG1, and APOE in macrophages through increased endogenous synthesis of 24(S),25-epoxycholesterol
    • Beyea, M.M., Heslop, C.L., Sawyez, C.G., Edwards, J.Y., Markle, J.G., Hegele, R.A. and Huff, M.W. (2007) Selective upregulation of LXR-regulated genes ABCA1, ABCG1, and APOE in macrophages through increased endogenous synthesis of 24(S),25-epoxycholesterol. Journal of Biological Chemistry, 282, 5207-5216.
    • (2007) Journal of Biological Chemistry , vol.282 , pp. 5207-5216
    • Beyea, M.M.1    Heslop, C.L.2    Sawyez, C.G.3    Edwards, J.Y.4    Markle, J.G.5    Hegele, R.A.6    Huff, M.W.7
  • 92
    • 33644651160 scopus 로고    scopus 로고
    • Liver X receptors as integrators of metabolic and inflammatory signaling
    • Zelcer, N. and Tontonoz, P. (2006) Liver X receptors as integrators of metabolic and inflammatory signaling. Journal of Clinical Investigation, 116, 607-614.
    • (2006) Journal of Clinical Investigation , vol.116 , pp. 607-614
    • Zelcer, N.1    Tontonoz, P.2
  • 93
    • 33845635077 scopus 로고    scopus 로고
    • A nuclear receptor corepressor-dependent pathway mediates suppression of cytokine-induced Creactive protein gene expression by liver X receptor
    • Blaschke, F., Takata, Y., Caglayan, E., Collins, A., Tontonoz, P., Hsueh, W.A. and Tangirala, R.K. (2006) A nuclear receptor corepressor-dependent pathway mediates suppression of cytokine-induced Creactive protein gene expression by liver X receptor. Circulation Research, 99, e88-e99.
    • (2006) Circulation Research , vol.99 , pp. e88-e99
    • Blaschke, F.1    Takata, Y.2    Caglayan, E.3    Collins, A.4    Tontonoz, P.5    Hsueh, W.A.6    Tangirala, R.K.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.