Enhanced oral bioavailability of Wurenchun (Fructus Schisandrae Chinensis Extracts) by self-emulsifying drug delivery systems

Drug Development and Industrial Pharmacy

Volumn 36, Issue 11, 2010, Pages 1356-1363

  Shao, Bing ^a   Tang, Jingling ^a   Ji, Hongyu ^a   Liu, Hongmei ^a   Liu, Yan ^a   Zhu, Daling ^a   Wu, Linhua ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Bioavailability; Schisandrin; Schisandrin B; Self emulsifying drug delivery systems; Wurenchun (Fructus Schisandrae extracts)

Indexed keywords

CHINESE DRUG; DIETHYLENE GLYCOL MONOETHYL ETHER; PLANT EXTRACT; SCHISANDRAE CHINENSIS EXTRACT; SCHIZANDRIN B; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DISSOLUTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG SOLUBILITY; EMULSION; MALE; MAXIMUM PLASMA CONCENTRATION; MEDICAL LITERATURE; NONHUMAN; PARTICLE SIZE; RAT;

ADMINISTRATION, ORAL; ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CYCLOOCTANES; DRUG DELIVERY SYSTEMS; DRUGS, CHINESE HERBAL; EMULSIONS; EXCIPIENTS; FRUIT; LIGNANS; MALE; PARTICLE SIZE; PLANT EXTRACTS; POLYCYCLIC COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY; SCHISANDRA; SOLUBILITY;

EID: 77956928063     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2010.480975     Document Type: Article

References (30)

1. Lebedev AA. (1971). Limonnik (Schizandra chinensis). Tashkent, Uzbek: Medicina Publishing House.
2. Hancke JL, Burgos RA, Ahumada F. (1999). Schisandra chinensis (Turcz) Baill. Fitoterapia, 70:451-471
3. Wang SC, Tian WB, Li JF, Liu MY. (2001). Effects of Schisandra chinensis Turcz. and Schisandra chinensis Turcz. Compatible with salvia miltiorrhiza bge ganoderma lucidum and bupleurum chinense DC on chronic liver injuries. Pharm J Chin PLA, 17:4-7.
4. Chiba Y, Kohri N, Iseki K, Miyazaki K. (1991). Improvement of dissolution and bioavailability for mebendazole, an agent for human echinococcosis, by preparing solid dispersion with polyethylene glycol. Chem Pharm Bull, 39:2158-2160
5. Kislalioglu MS, Khan MA, Lount CB, Goettsch RW, Bolton S. (1991). Physical characterization and dissolution properties of ibuprofen: Eudragit coprecipitates. J Pharm Sci, 80:799-804.
6. Ho HO, Su HL, Tsai T, Sheu MT. (1996). The preparation and characterization of solid dispersions on pellets using a fluidizedbed system. Int J Pharm, 139:223-229
7. Moyano JR, Arias MJ, Gines JM, Rabasco AM. (1997). Dissolution behavior of oxazepamin presence of cyclodextrins-evaluation of oxazepam-dimeb binary system. Drug Dev Ind Pharm, 23:379-385
8. Okonogi S, Oguchi T, Yonemochi E, Puttipipatkhachorn S, Yamamoto K. (1997). Improved dissolution of ofloxacin via solid dispersion. Int J Pharm, 156:175-180
9. Yoo SD, Lee SH, Kang E, Jun H, Jung JY, Park JW, et al. (2000). Bioavailability of itraconazole in rats and rabbits after administration of tablets containing solid dispersion particles. Drug Dev Ind Pharm, 26:27-34.
10. Kim CK, Cho YJ, Gao ZG. (2001). Preparation and evaluation of biphenyl dimethyl dicarboxylate microemulsions for oral delivery. J Control Release, 70:149-155
11. Charman SA, Charman WN, Rogge MC, Wilson TD, Dutko FJ, Pouton CW. (1992). Self-emulsifying drug delivery systems: Formulation and biopharmaceutic evaluation of an investigational lipophilic compound. Pharm Res, 9:87-93.
12. Craig DQM, Lievens HSR, Pitt KG, Storey DE. (1993). An investigation into the physicochemical properties of self-emulsifying systems using low frequency dielectric spectroscopy, surface tension measurement and particle size analysis. Int J Pharm, 96:147-155
13. Gershanik T, Benita S. (2000). Self-dispersing lipid formulations for improving oral absorption of lipophilic drugs. Eur J Pharm Biopharm, 50:179-188
14. Gursoy RN, Benita S. (2004). Self-emulsifying drug delivery systems (SEDDS) for improved oral delivery of lipophilic drugs. Biomed Pharmacother, 58:173-182
15. Shah NH, Carvajal MT, Patel CI, Infeld MH, Malick AW. (1994). Self-emulsifying drug delivery systems (SEDDS) with polyglycolyzed glycerides for improving in vitro dissolution and oral absorption of lipophilic drugs. Int J Pharm, 106:15-23.
16. You J, Cui FD, Li QP, Han X, Yu YW, Yang MS. (2005). A novel formulation design about water-insoluble oily drug: Preparation of zedoary turmeric oil microspheres with self-emulsifying ability and evaluation in rabbits. Int J Pharm, 288:315-323
17. Tang JL, Sun J, Cui FD, Zhang TH, Liu XH, He ZG. (2008). Selfemulsifying drug delivery systems for improving oral absorption of ginkgo biloba extracts. Drug Deliv, 15:477-484
18. Kommuru TR, Gurley B, Khan MA, Reddy IK. (2001). Selfemulsifying drug delivery systems (SEDDS) of coenzyme Q10: Formulation development and bioavailability assessment. Int J Pharm, 212:233-246
19. Ono H, Matsuzaki Y, Wakui Y, Takeda S, Ikeya Y, Amagaya S, et al. (1995). Determination of schizandrin in human plasma by gaschromatography-mass spectrometry. J Chromatogr B, 674:293-297
20. Xu MJ, Wang GJ, Xie HT, Huang Q, Wang W, Jia YW. (2008). Pharmacokinetic comparisons of schizandrin after oral administration of schizandrin monomer, Fructus Schisandrae aqueous extractand. J Ethnopharmacol, 115:483-488
21. Gu Y, Wang SC, Gao SL, Jiang YP. (2001). Relative bioavailability of Wuling capsule in rabbits. J Fourth Military Med Univ, 22:453-455
22. Deng XX, Chen XH, Yin R, Shen ZD, Qiao L, Bi KS. (2008). Determination of deoxyschizandrin in rat plasma by LC-CM. J Pharm Biomed Anal, 46:121-126
23. Kang BK, Lee JS, Chon SK, Jeong SY, Yuk SH, Khang G, et al. (2004). Development of self-microemulsifying drug delivery systems (SMEDDS) for oral bioavailability enhancement of simvastatin in beagle dogs. Int J Pharm, 274:65-73.
24. Pouton CW. (1997). Formulation of self-emulsifying drug delivery systems. Adv Drug Deliv Rev, 25:47-58.
25. Levy MY, Benita S. (1990). Drug release from submicronized O/W emulsion: A new in vitro kinetic evaluation model. Int J Pharm, 66:29-37.
26. Cui SX, Nie SF, Li L, Wang CG, Pan WS, Sun JP. (2009). Preparation and evaluation of self-microemulsifying drug delivery system containing vinpocetine. Drug Dev Ind Pharm, 35:603-611
27. Balakrishnan P, Lee BJ, Oh DH, Kim JO, Lee YI, Kim DD, et al. (2009). Enhanced oral bioavailability of coenzyme Q10 by selfemulsifying drug delivery systems. Int J Pharm, 374:66-72.
28. Patel D, Sawant KK. (2007). Oral bioavailability enhancement of acyclovir by self-microemulsifying drug delivery systems (SMEDDS). Drug Dev Ind Pharm, 33:1318-1326
29. Cui S, Zhao C, Chen D, He Z. (2005). Self-microemulsifying drug delivery systems (SMEDDS) for improving in vitro dissolution and oral absorption of pueraria lobata isoflavone. Drug Dev Ind Pharm, 31:349-356
30. Wang SC, Huangfu MJ, Zhao HP, Cao ZF. (2004). Pharmacokinetic study of schizandrin in Wuling capsules in mice. Lishizhen Med Mater Med Res, 15:468-470