Self-emulsifying drug delivery systems for improving oral absorption of Ginkgo biloba extracts

Drug Delivery

Volumn 15, Issue 8, 2008, Pages 477-484

  Tang, Jingling ^a,b   Sun, Jin ^a   Cui, Fude ^a   Zhang, Tianhong ^a   Liu, Xiaohong ^a   He, Zhonggui ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Bioavailability; Ginkgo biloba extracts; Self emulsifying drug delivery systems

Indexed keywords

BILABOLIDE; CREMOPHOR; GINKGO BILOBA EXTRACT; GINKGOLIDE A; GINKGOLIDE B; LACTONE DERIVATIVE; MIGLYOL; OLEIC ACID ETHYL ESTER; POLYSORBATE 80; PROPYLENE GLYCOL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BRAIN DYSFUNCTION; COGNITION; DIET RESTRICTION; DISPERSION; DOG; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG FORMULATION; DRUG HALF LIFE; DRUG SOLUBILITY; EMULSION; IN VITRO STUDY; NONHUMAN; PARTICLE SIZE; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; SELF EMULSIFYING DRUG DELIVERY SYSTEM; SINGLE DRUG DOSE; TABLET;

ADMINISTRATION, ORAL; ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; DOGS; DRUG DELIVERY SYSTEMS; DRUGS, CHINESE HERBAL; EMULSIFYING AGENTS; GINKGO BILOBA; SOLUBILITY; TABLETS;

EID: 54049096692     PISSN: 10717544     EISSN: 15210464     Source Type: Journal    
DOI: 10.1080/10717540802039089     Document Type: Article

References (26)

1. Blumenthal, M., Busse, W. R., Goldberg, A., Gruenwald, J., Hall, T., Riggins, C. W., and Rister, R. S. (eds.) 1998. Klein, S., and Rister, R. S. (trans.) The Complete German Commission E Monographs - Therapeutic Guide to Herbal Medicines, 136-138. Austin, TX: American Botanical Council; Boston, MA: Integrative Medicine Communication.
2. Blumenthal, M. 2001. Herb sales down 15% in mainstream market. Herbal Gram. 51:69.
3. Charman, S. A., Charman, W. N., Rogge, M. C., Wilson, T. D., Dutko, F. J., and Pouton, C. W. 1992. Self-emulsifying drug delivery systems: formulation and biopharmaceutic evaluation of an investigational lipophilic compound. Pharm. Res. 9(1):87-93.
4. Craig, D. Q. M., Lievens, H. S. R., Pitt, K. G., and Storey, D. E. 1993. An investigation into the physicochemical properties of self-emulsifying systems using lowfrequency dielectric spectroscopy, surface tension measurement and particle size analysis. Int. J. Pharm. 96(1-3):147-155.
5. Craig, D. Q. M., Barker, S. A., Banning, D., and Booth, S. W. 1995. Investigation into the mechanisms of self-emulsification using particle size analysis and low frequency dielectric spectroscopy. Int. J. Pharm. 114(1):103-110.
6. Engels, T., Förster, T., and Rybinsko, W. V. 1995. The influence of coemulsifier type on the stability of oil-in-water emulsions. Colloids. Surf. A: Physicochem. Eng. Aspects. 99(2-3):141-149.
7. Foster, S. 1996. Ginkgo-ginkgo biloba. Botanical Booklet No. 304. Austin, TX: American. Botanical. Council.
8. Gershanik, T., and Benita, S. 2000. Self-dispersing lipid formulations for improving oral absorption of lipophilic drugs. Eur. J. Pharm. Biopharm. 50(1):179-188.
9. Gursoy, R. N., and Benita, S. 2004. Self-emulsifying drug delivery systems (SEDDS) for improved oral delivery of lipophilic drugs. Biomed. Pharmacother. 58(3):173-182.
10. Kang, B. K., Lee, J. S., Chon, S. K., Jeong, S. Y., Yuk, S. H., Khang, G., Lee, H. B., and Cho, S. H. 2004. Development of self-microemulsifying drug delivery systems (SMEDDS) for oral bioavailability enhancement of simvastatin in beagle dogs. Int. J. Pharm. 274(1-2):65-73.
11. Kommuru, T. R., Gurley, B., Khan, M. A., and Reddy, I. K. 2001. Self-emulsifying drug delivery systems (SEDDS) of coenzyme Q10: formulation development and bioavailability assessment. Int. J. Pharm. 212(2):233-246.
12. Kressmann, S., Muller, W. E., and Blume, H. H. 2002a. Pharmaceutical quality of different Ginkgo biloba brands. J. Pharm. Pharmacol 54(5):661-669.
13. Kressmann, S., Biber, A., Wonnemann, M., Schug, B., Blume, H. H., and Muller, W. E. 2002b. Influence of pharmaceutical quality on the bioavailability of active components from Ginkgo biloba preparations. J. Pharm. Pharmacol. 54(11):1507-1514.
14. Levy, M. Y., and Benita S. 1990. Drug release from submicronized O/W emulsion: a new in vitro kinetic evaluation model. Int. J. Pharm. 66(1-3):29-37.
15. Li, P., Ghosh, A., Wagner, R. F., Krill, S., Joshi, Y. M., and Serajuddin, A. T. 2005. Effect of combined use of nonionic surfactant on formation of oil-in-water microemulsions. Int. J. Pharm. 288(1):27-34.
16. Moreno, M. A., Ballesteros, M. P., and Frutos, P. 2003. Lecithin-based oilin-water microemulsions for parenteral use: pseudoternary phase diagrams, characterization and toxicity studies. J. Pharm. Sci. 92(7):1428-1437.
17. Ninham, B. W., Chen, S. J., and Evans, D. F. 1984. Role of oils and other factors in microemulsion design. J. Phys. Chem. 88(24):5855-5857.
18. Oken, B. S., Storzbach, D. M., and Kaye, J. A. 1998. The efficacy of Ginkgo biloba on cognitive function in Alzheimer disease. Arch. Neurol. 55(11):1409-1415.
19. Pouton, C. W. 1997. Formulation of self-emulsifying drug delivery systems. Adv. Drug. Del. Rev. 25(1):47-58.
20. Shah, N. H., Carvajal, M. T., Patel, C. I., Infeld, M. H., and Malick, A. W. 1994. Self-emulsifying drug delivery systems (SEDDS) with polyglycolyzed glycerides for improving in vitro dissolution and oral absorption of lipophilic drugs. Int. J. Pharm. 106(1):15-23.
21. Tang, J. L., Sun, J., Cui, F. D., and He, Z. G. 2006a Preparation of self-emulsifying drug delivery systems of Ginkgo biloba extracts and in vitro dissolution study. Asian J. Trad. Med. 1(3-4):138-141.
22. Tang, J. L., Sun, J., Sun, Y. H., Cui, F. D., and He, Z. G. 2006b. LC-ESI-MS determination of bilobalide and ginkgolides in canine plasma. Chromatographia 63(1):53-58.
23. Van Beek, T. A. 2005. Ginkgolides and bilobalide: their physical, chromatographic and spectroscopic properties. Bioorg. Med. Chem. 13(17):5001-5012.
24. Warisnoicharoen, W., Lansley, A. B., and Lawrence, M. J. 2000. Nonionic oil-in-water micro-emulsions: the effect of oil type on phase behaviour. Int. J. Pharm. 198(1):7-27.
25. Weingarten, C., Magalhaes, N. S. S., Baszkin, A., Benita, S., and Seiller, M. 1991. Interaction of a nonionic ABA copolymer surfactant with phospholipid monolayers: possible relevance to emulsion stabilization. Int. J. Pharm. 75(2-3):171-179.
26. Yang, Y. J., Ping, Q. N., and Song, Y. M. 2004. Improvement of the dissolution rate of Ginkgo biloba tablets by using solid dispersion methods. Zhong. Gou. Xin. Yao. Za. Zhi. 13(6):521-524.