IL-3 inhibits human osteoclastogenesis and bone resorption through downregulation of c-Fms and diverts the cells to dendritic cell lineage

Journal of Immunology

Volumn 185, Issue 4, 2010, Pages 2261-2272

  Gupta, Navita ^a   Barhanpurkar, Amruta P ^a   Tomar, Geetanjali B ^a   Srivastava, Rupesh K ^a   Kour, Supinder ^a   Pote, Satish T ^a   Mishra, Gyan C ^a   Wani, Mohan R ^a  

^a NATIONAL CENTRE FOR CELL SCIENCE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; BETA3 INTEGRIN; C FMS RECEPTOR; CARBOXY TERMINAL TELOPEPTIDE; CATHEPSIN K; CD123 ANTIGEN; CD14 ANTIGEN; COLONY STIMULATING FACTOR 1; INTERLEUKIN 3; MESSENGER RNA; OSTEOCLAST DIFFERENTIATION FACTOR; PROTEIN; PROTEIN C FOS; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; T6 ANTIGEN; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR PU 1; TRANSCRIPTION FACTOR RELB; UNCLASSIFIED DRUG; COLONY STIMULATING FACTOR RECEPTOR; INTERLEUKIN 3 RECEPTOR; OSTEOPROTEGERIN;

ADULT; ARTICLE; CELL DIFFERENTIATION; DENDRITIC CELL; DOWN REGULATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MONOCYTE; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; PERIPHERAL BLOOD MONONUCLEAR CELL; POSTMENOPAUSE OSTEOPOROSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; AGED; CELL CULTURE; CELL LINEAGE; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; FLOW CYTOMETRY; GENE EXPRESSION; GENETICS; METABOLISM; MIDDLE AGED; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADULT; AGED; BONE RESORPTION; CELL DIFFERENTIATION; CELL LINEAGE; CELLS, CULTURED; DENDRITIC CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; FLOW CYTOMETRY; GENE EXPRESSION; HUMANS; INTERLEUKIN-3; MIDDLE AGED; OSTEOCLASTS; OSTEOPROTEGERIN; RANK LIGAND; RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR; RECEPTORS, INTERLEUKIN-3; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; YOUNG ADULT;

EID: 77956915897     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1000015     Document Type: Article

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