The effect of macrophage-colony stimulating factor and other humoral factors (interleukin-1, -3, -6, and -11, tumor necrosis factor-α, and granulocyte macrophage-colony stimulating factor) on human osteoclast formation from circulating cells

Bone

Volumn 28, Issue 3, 2001, Pages 261-267

  Fujikawa, Y ^a,b   Sabokbar, A ^a   Neale, S D ^a   Itonaga, I ^a   Torisu, T ^b   Athanasou, N A ^c  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b OITA UNIVERSITY   (Japan)

^c NUFFIELD ORTHOPAEDIC CENTRE   (United Kingdom)

Author keywords

Bone resorption; GM CSF; Human osteoclasts; IL 3; M CSF; Monocytes

Indexed keywords

CALCITRIOL; COLONY STIMULATING FACTOR 1; DEXAMETHASONE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 11; INTERLEUKIN 1BETA; INTERLEUKIN 3; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; HUMAN; HUMAN CELL; IN VITRO STUDY; MONOCYTE; MULTINUCLEAR CELL; OSTEOCLAST; OSTEOLYSIS;

ADULT; CELL DIVISION; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; INTERLEUKINS; MACROPHAGE COLONY-STIMULATING FACTOR; OSTEOCLASTS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035118728     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S8756-3282(00)00453-1     Document Type: Article

References (33)

1. Immunophenotypic differences between osteoclasts and macrophage polykaryons; Immunohistological distinction and implications for osteoclast ontogeny and function
2. Impairment of macrophage colony-stimulating factor production and lack of resident bone marrow macrophage in the osteopetrotic op/op mouse
3. The human osteoclast precursor circulates in the monocyte fraction
4. Macrophage colony-stimulating factor stimulates survival and chemotactic behaviour in isolated osteoclasts
5. Interleukin-11; A new cytokine critical for osteoclast development
6. Monoclonal antibodies to osteoclastomas (giant cell bone tumors); Definition of osteoclast-specific cellular antigens
7. Macrophage colony-stimulating factor and interleukin-1 alpha maintain the survival of osteoclast-like cells
8. Interleukin-6 stimulates osteoclast-like multinucleated cell formation in long-term human marrow cultures by inducing IL-1 release
9. 2, Interleukin 1α, and tumor necrosis factor-α increase human osteoclast formation and bone resorption in vitro
10. Human blood-mobilized hematopoietic precursors differentiate into osteoclasts in the absence of stromal cells
11. Osteoclast differentiation factor (ODF) induces osteoclast-like cell formation in human peripheral blood mononuclear cell cultures
12. Bone acid phosphatase; Tartrate-resistant acid phosphatase as a marker of osteoclast function
13. Local concentrations of macrophage colony-stimulating factor mediate osteoclastic differentiation
14. Interleukin-1 and tumor necrosis factor stimulate the formation of human osteoclastlike cells in vitro
15. A combination of osteoclast differentiation factor and macrophage-colony stimulating factor is sufficient for both human and mouse osteoclast formation in vitro
16. The role of gp130-mediated signals in osteoclast development; Regulation of interleukin 11 production by osteoblasts and distribution of its receptor in bone marrow cultures
17. A point mutation in the extracellular domain of the human CSF-1 receptor (c-fms product) activates its transforming potential
18. Macrophage colony-stimulating factor stimulates bone resorption by isolated osteoclasts disaggregated from human foetal bones by increasing osteoclast survival
19. The effect of hemopoietic growth factors on the generation of osteoclast-like cells in mouse bone marrow cultures
20. Factors regulating macrophage production and growth; Purification and some properties of the colony-stimulating factor from medium conditioned by mouse L cells
21. Macrophage colony stimulating factor (M-CSF) is essential for differentiation rather than proliferation of osteoclast progenitors
22. Modulation of osteoclast differentiation by local factors
23. Role of colony stimulating factors in osteoclast development
24. A new member of tumor necrosis factor ligand family, ODF/OPGL/TRANCE/RANKL, regulates osteoclast differentiation and function
25. Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6
26. Macrophage colony-stimulating factor is indispensable for both proliferation and differentiation of osteoclast progenitors
27. Interleukin-18 (interferon-gamma-inducing factor) is produced by osteoblasts and acts via granulocyte/macrophage colony-stimulating factor and not via interferon-gamma to inhibit osteoclast formation
28. Origin of the osteoclast; Mature monocytes and macrophages are capable of differentiating into osteoclasts under a suitable microenvironment prepared by bone marrow derived cells
29. Osteoblasts/stromal cells stimulate osteoclast activation through expression of osteoclast differentiation factor/RANKL but not macrophage colony-stimulating factor
30. Granulocyte-macrophage colony stimulating factor corrects macrophage deficiency, but not osteopetrosis, in the colony-stimulating factor-1 deficient op/op mouse
31. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis inhibitory factor and is identical to TRANCE/RANKL