Stromal cell-derived CXCL12 and CCL8 cooperate to support increased development of regulatory dendritic cells following Leishmania infection

Journal of Immunology

Volumn 185, Issue 4, 2010, Pages 2360-2371

  Hoang, Anh Thu Nguyen ^a   Liu, Hao ^b   Juaréz, Julius ^a   Aziz, Naveed ^b   Kaye, Paul M ^b   Svensson, Mattias ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF YORK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; MONOCYTE CHEMOTACTIC PROTEIN 2; RECOMBINANT PROTEIN; STROMAL CELL DERIVED FACTOR 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL MATURATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELL; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IMMUNOMODULATION; LEISHMANIA DONOVANI; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; STEM CELL; STROMA CELL; VISCERAL LEISHMANIASIS; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CELL CULTURE; CELL LINE; CLUSTER ANALYSIS; COCULTURE; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENETICS; HAMSTER; HOST PATHOGEN INTERACTION; MACROPHAGE; METABOLISM; PARASITOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; CELLS, CULTURED; CHEMOKINE CCL8; CHEMOKINE CXCL12; CLUSTER ANALYSIS; COCULTURE TECHNIQUES; CRICETINAE; DENDRITIC CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; HEMATOPOIETIC STEM CELLS; HOST-PATHOGEN INTERACTIONS; LEISHMANIA DONOVANI; LEISHMANIASIS, VISCERAL; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STROMAL CELLS;

EID: 77956906704     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0903673     Document Type: Article

References (48)

1. Adams, G. B., and D. T. Scadden. 2006. The hematopoietic stem cell in its place. Nat. Immunol. 7: 333-337.
2. Wright, D. E., E. P. Bowman, A. J. Wagers, E. C. Butcher, and I. L. Weissman. 2002. Hematopoietic stem cells are uniquely selective in their migratory response to chemokines. J. Exp. Med. 195: 1145-1154.
3. Wright, D. E., A. J. Wagers, A. P. Gulati, F. L. Johnson, and I. L. Weissman. 2001. Physiological migration of hematopoietic stem and progenitor cells. Science 294: 1933-1936.
4. Sugiyama, T., H. Kohara, M. Noda, and T. Nagasawa. 2006. Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches. Immunity 25: 977-988.
5. Ma, Q., D. Jones, P. R. Borghesani, R. A. Segal, T. Nagasawa, T. Kishimoto, R. T. Bronson, and T. A. Springer. 1998. Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice. Proc. Natl. Acad. Sci. USA 95: 9448-9453.
6. Nagasawa, T., S. Hirota, K. Tachibana, N. Takakura, S. Nishikawa, Y. Kitamura, N. Yoshida, H. Kikutani, and T. Kishimoto. 1996. Defects of B-cell lymphopoiesis and bone-marrowmyelopoiesis in mice lacking theCXCchemokine PBSF/SDF-1. Nature 382: 635-638.
7. Tachibana, K., S. Hirota, H. Iizasa, H. Yoshida, K. Kawabata, Y. Kataoka, Y. Kitamura, K. Matsushima, N. Yoshida, S. Nishikawa, et al. 1998. The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract. Nature 393: 591-594.
8. Zou, Y. R., A. H. Kottmann, M. Kuroda, I. Taniuchi, and D. R. Littman. 1998. Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature 393: 595-599.
9. Massberg, S., P. Schaerli, I. Knezevic-Maramica, M. Köllnberger, N. Tubo, E. A. Moseman, I. V. Huff, T. Junt, A. J. Wagers, I. B. Mazo, and U. H. von Andrian. 2007. Immunosurveillance by hematopoietic progenitor cells trafficking through blood, lymph, and peripheral tissues. Cell 131: 994-1008.
10. Abkowitz, J. L., A. E. Robinson, S. Kale, M. W. Long, and J. Chen. 2003. Mobilization of hematopoietic stem cells during homeostasis and after cytokine exposure. Blood 102: 1249-1253. (Pubitemid 36988029)
11. Bensinger, W., J. F. DiPersio, and J. M. McCarty. 2009. Improving stem cell mobilization strategies: future directions. Bone Marrow Transplant. 43: 181-195.
12. Cardier, J. E., and E. Barberá-Guillem. 1997. Extramedullary hematopoiesis in the adult mouse liver is associated with specific hepatic sinusoidal endothelial cells. Hepatology 26: 165-175.
13. McKinney-Freeman, S. L., K. A. Jackson, F. D. Camargo, G. Ferrari, F. Mavilio, and M. A. Goodell. 2002. Muscle-derived hematopoietic stem cells are hematopoietic in origin. Proc. Natl. Acad. Sci. USA 99: 1341-1346.
14. Shortman, K., and Y. J. Liu. 2002. Mouse and human dendritic cell subtypes. Nat. Rev. Immunol. 2: 151-161.
15. Shortman, K., and S. H. Naik. 2007. Steady-state and inflammatory dendritic-cell development. Nat. Rev. Immunol. 7: 19-30.
16. Liu, K., C. Waskow, X. Liu, K. Yao, J. Hoh, and M. Nussenzweig. 2007. Origin of dendritic cells in peripheral lymphoid organs of mice. Nat. Immunol. 8: 578-583.
17. Poulin, L. F., S. Henri, B. de Bovis, E. Devilard, A. Kissenpfennig, and B. Malissen. 2007. The dermis contains langerin+ dendritic cells that develop and function independently of epidermal Langerhans cells. J. Exp. Med. 204: 3119-3131.
18. Waskow, C., K. Liu, G. Darrasse-Jèze, P. Guermonprez, F. Ginhoux, M. Merad, T. Shengelia, K. Yao, and M. Nussenzweig. 2008. The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues. Nat. Immunol. 9: 676-683.
19. Smits, H. H., E. C. de Jong, E. A. Wierenga, and M. L. Kapsenberg. 2005. Different faces of regulatory DCs in homeostasis and immunity. Trends Immunol. 26: 123-129.
20. Steinman, R. M., D. Hawiger, and M. C. Nussenzweig. 2003. Tolerogenic dendritic cells. Annu. Rev. Immunol. 21: 685-711.
21. Svensson, M., and P. M. Kaye. 2006. Stromal-cell regulation of dendritic-cell differentiation and function. Trends Immunol. 27: 580-587.
22. Tang, H., Z. Guo, M. Zhang, J. Wang, G. Chen, and X. Cao. 2006. Endothelial stroma programs hematopoietic stem cells to differentiate into regulatory dendritic cells through IL-10. Blood 108: 1189-1197. (Pubitemid 44232014)
23. Svensson, M., A. Maroof, M. Ato, and P. M. Kaye. 2004. Stromal cells direct local differentiation of regulatory dendritic cells. Immunity 21: 805-816.
24. Xia, S., Z. Guo, X. Xu, H. Yi, Q. Wang, and X. Cao. 2008. Hepatic microenvironment programs hematopoietic progenitor differentiation into regulatory dendritic cells, maintaining liver tolerance. Blood 112: 3175-3185.
25. Wakkach, A., N. Fournier, V. Brun, J. P. Breittmayer, F. Cottrez, and H. Groux. 2003. Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo. Immunity 18: 605-617. (Pubitemid 36588578)
26. Zhang, M., H. Tang, Z. Guo, H. An, X. Zhu, W. Song, J. Guo, X. Huang, T. Chen, J. Wang, and X. Cao. 2004. Splenic stroma drives mature dendritic cells to differentiate into regulatory dendritic cells. Nat. Immunol. 5: 1124-1133.
27. Akbari, O., R. H. DeKruyff, and D. T. Umetsu. 2001. Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen. Nat. Immunol. 2: 725-731.
28. Li, Q., Z. Guo, X. Xu, S. Xia, and X. Cao. 2008. Pulmonary stromal cells induce the generation of regulatory DC attenuating T-cell-mediated lung inflammation. Eur. J. Immunol. 38: 2751-2761.
29. Cotterell, S. E., C. R. Engwerda, and P. M. Kaye. 2000. Leishmania donovani infection of bone marrow stromal macrophages selectively enhances myelopoiesis, by a mechanism involving GM-CSF and TNF-alpha. Blood 95: 1642-1651.
30. Engwerda, C. R., M. Ato, S. E. Cotterell, T. L. Mynott, A. Tschannerl, P. M. Gorak-Stolinska, and P. M. Kaye. 2002. A role for tumor necrosis factor-alpha in remodeling the splenic marginal zone during Leishmania donovani infection. Am. J. Pathol. 161: 429-437.
31. Cotterell, S. E., C. R. Engwerda, and P. M. Kaye. 2000. Enhanced hematopoietic activity accompanies parasite expansion in the spleen and bone marrow of mice infected with Leishmania donovani. Infect. Immun. 68: 1840-1848.
32. Sponaas, A. M., E. T. Cadman, C. Voisine, V. Harrison, A. Boonstra, A. O'Garra, and J. Langhorne. 2006. Malaria infection changes the ability of splenic dendritic cell populations to stimulate antigen-specific T cells. J. Exp. Med. 203: 1427-1433.
33. Bookout, A. L., C. L. Cummins, D. J. Mangelsdorf, J. M. Pesola, and M. F. Kramer. 2006. High-throughput real-time quantitative reverse transcription PCR. Curr. Protoc. Mol. Biol. Chapter 15:Unit 15.8.
34. Zipori, D., D. Duksin, M. Tamir, A. Argaman, J. Toledo, and Z. Malik. 1985. Cultured mouse marrow stromal cell lines. II. Distinct subtypes differing in morphology, collagen types, myelopoietic factors, and leukemic cell growth modulating activities. J. Cell. Physiol. 122: 81-90.
35. Jacobson, S., M. Kumagai-Braesch, A. Tibell, M. Svensson, and M. Flodström-Tullberg. 2008. Co-transplantation of stromal cells interferes with the rejection of allogeneic islet grafts. Ann. N. Y. Acad. Sci. 1150: 213-216.
36. Thelen, M. 2001. Dancing to the tune of chemokines. Nat. Immunol. 2: 129-134.
37. Neves, S. R., P. T. Ram, and R. Iyengar. 2002. G protein pathways. Science 296: 1636-1639.
38. Cotterell, S. E., C. R. Engwerda, and P. M. Kaye. 1999. Leishmania donovani infection initiates T cell-independent chemokine responses, which are subsequently amplified in a T cell-dependent manner. Eur. J. Immunol. 29: 203-214.
39. Despars, G., K. Ni, A. Bouchard, T. J. O'Neill, and H. C. O'Neill. 2004. Molecular definition of an in vitro niche for dendritic cell development. Exp. Hematol. 32: 1182-1193.
40. Nie, Y., Y. C. Han, and Y. R. Zou. 2008. CXCR4 is required for the quiescence of primitive hematopoietic cells. J. Exp. Med. 205: 777-783.
41. Benarafa, C., F. M. Cunningham, A. S. Hamblin, D. W. Horohov, and M. E. Collins. 2000. Cloning of equine chemokines eotaxin, monocyte chemoattractant protein (MCP)-1, MCP-2 and MCP-4, mRNA expression in tissues and induction by IL-4 in dermal fibroblasts. Vet. Immunol. Immunopathol. 76: 283-298.
42. Ellyard, J. I., D. T. Avery, C. R. Mackay, and S. G. Tangye. 2005. Contribution of stromal cells to the migration, function and retention of plasma cells in human spleen: potential roles of CXCL12, IL-6 and CD54. Eur. J. Immunol. 35: 699-708.
43. Teixeira, M. J., C. R. Teixeira, B. B. Andrade, M. Barral-Netto, and A. Barral. 2006. Chemokines in host-parasite interactions in leishmaniasis. Trends Parasitol. 22: 32-40.
44. Bogunovic, M., F. Ginhoux, A. Wagers, M. Loubeau, L. M. Isola, L. Lubrano, V. Najfeld, R. G. Phelps, C. Grosskreutz, E. Scigliano, et al. 2006. Identification of a radio-resistant and cycling dermal dendritic cell population in mice and men. J. Exp. Med. 203: 2627-2638.
45. Naik, S. H., D. Metcalf, A. van Nieuwenhuijze, I. Wicks, L. Wu, M. O'Keeffe, and K. Shortman. 2006. Intrasplenic steady-state dendritic cell precursors that are distinct from monocytes. Nat. Immunol. 7: 663-671.
46. Resnick, M., E. Fibach, M. Lebastard, L. Levy, and H. Bercovier. 1988. Response of the murine hematopoietic system to chronic infection with Mycobacterium lepraemurium. Infect. Immun. 56: 3145-3151.
47. Villeval, J. L., A. Gearing, and D. Metcalf. 1990. Changes in hemopoietic and regulator levels in mice during fatal or nonfatal malarial infections. II. Nonerythroid populations. Exp. Parasitol. 71: 375-385.
48. Gabrilovich, D. I., and S. Nagaraj. 2009. Myeloid-derived suppressor cells as regulators of the immune system. Nat. Rev. Immunol. 9: 162-174.