Per2 inhibits K562 leukemia cell growth in vitro and in vivo through cell cycle arrest and apoptosis induction

Pathology and Oncology Research

Volumn 16, Issue 3, 2010, Pages 403-411

  Sun, Cheng Ming ^a   Huang, Shi Feng ^a   Zeng, Jian Ming ^a   Liu, Din Bing ^a   Xiao, Qing ^a   Tian, Wen Jun ^a   Zhu, Xi Dan ^a   Huang, Zong Gan ^a   Feng, Wen Li ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Cell cycle arrest; Circadian clock; K562 cell; Per2

Indexed keywords

CYCLIN B1; DNA; MYC PROTEIN; PER2 PROTEIN; PLASMID VECTOR; PROTEIN P53;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER GENE THERAPY; CANCER GROWTH; CANCER INFILTRATION; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL PROLIFERATION; CELL STRAIN K 562; CELL STRUCTURE; CHRONIC MYELOID LEUKEMIA; CIRCADIAN RHYTHM; CONTROLLED STUDY; DNA FRAGMENTATION; DOWN REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LEUKEMIA CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SEPARATION; CYCLIN B1; DNA FRAGMENTATION; FLOW CYTOMETRY; HUMANS; IN SITU NICK-END LABELING; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; MICE; MICE, INBRED BALB C; PERIOD CIRCADIAN PROTEINS; PROTO-ONCOGENE PROTEINS C-MYC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 77956886221     PISSN: 12194956     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12253-009-9227-0     Document Type: Article

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