Acceptability and use of the diaphragm and replens® lubricant gel for HIV prevention in Southern Africa

AIDS and Behavior

Volumn 14, Issue 3, 2010, Pages 629-638

  Montgomery, Elizabeth T ^a,b   Cheng, Helen ^a   Der Straten, Ariane Van ^a,c   Chidanyika, Agnes C ^d   Lince, Naomi ^e   Blanchard, Kelly ^e   Ramjee, Gita ^g   Nkala, Busisiwe ^f   Padian, Nancy S ^a,h  

^a RTI INTERNATIONAL   (United States)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF ZIMBABWE   (Zimbabwe)

^e IBIS REPRODUCTIVE HEALTH   (United States)

^f Perinatal HIV Research Unit   (South Africa)

^g SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

^h UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Acceptability; Diaphragm; HIV prevention; Lubricant gel; Product adherence; South Africa; Zimbabwe

Indexed keywords

AGENTS USED INTRAVAGINALLY; LIPID; POLYCARBOPHIL;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE TRANSMISSION; FEMALE; FEMALE CONTRACEPTIVE DEVICE; HIGH RISK BEHAVIOR; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INTERVIEW; LUBRICATION; MALE; PATIENT ATTITUDE; PATIENT COMPLIANCE; RANDOMIZED CONTROLLED TRIAL; SEXUAL BEHAVIOR; SOUTH AFRICA; STATISTICAL MODEL; STATISTICS; TREATMENT OUTCOME; UTILIZATION REVIEW; ZIMBABWE;

ADULT; CONTRACEPTIVE DEVICES, FEMALE; FEMALE; HIV INFECTIONS; HUMANS; INTERVIEWS AS TOPIC; LIPIDS; LOGISTIC MODELS; LUBRICATION; MALE; PATIENT ACCEPTANCE OF HEALTH CARE; PATIENT COMPLIANCE; RISK-TAKING; SEXUAL BEHAVIOR; SOUTH AFRICA; TREATMENT OUTCOME; VAGINAL CREAMS, FOAMS, AND JELLIES; YOUNG ADULT; ZIMBABWE;

EID: 77956863024     PISSN: 10907165     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10461-009-9609-z     Document Type: Article

References (36)

1. UNAIDS. AIDS epidemic update 2007, regional summary: sub-Saharan Africa. Geneva: UNAIDS; 2008.
2. UNAIDS/WHO. 2004 Report on the global AIDS epidemic, July 2004.
3. Gray R, Wawer M, Brookmeyer R, et al. Probability of HIV-1 transmission per coital act in monogamous, heterosexual, HIV-1-discordant couples in Rakai, Uganda. Lancet. 2001;357(9263): 1149-53
4. European study group on heterosexual transmission of HIV. Comparison of female to male and male to female transmission of HIV in 563 stable couples. Brit Med J. 1992;304:809-13.
5. Padian NS, van der Straten A, Ramjee G, et al. Diaphragm and lubricant gel for prevention of HIV acquisition in southern African women: a randomised controlled trial. Lancet. 2007;370(9583):251-61.
6. Ramjee G, van der Straten A, Chipato T, et al. The diaphragm and lubricant gel for prevention of cervical sexually transmitted infections: results of a randomized controlled trial. PLoS ONE. 2008;3(10):e3488.
7. Elias C, Coggins C. Acceptability research on female-controlled barrier methods to prevent heterosexual transmission of HIV: where have we been? Where are we going? J Womens Health Gend Based Med. 2001;10(2):163-73.
8. Bulut A, Ortayli N, Ringheim K, et al. Assessing the acceptability, service delivery requirements, and use-effectiveness of the diaphragm in Colombia, Philippines, and Turkey. Contraception. 2001;63(5):267-75.
9. Ortayli N, Bulut A, Nalbant H, Cottingham J. Is the diaphragm a viable option for women in Turkey? Int Fam Plan Perspec. 2000;26(1):36-42.
10. Ravindran TKS, Rao S. Is the diaphragm a suitable method of contraception for low-income women: a user-perspective study, Madras, India. Beyond acceptability: user's perspectives on contraception-out of print-a World Health Organization Monograph. 1997.
11. Barnhart KT, Rosenberg MJ, MacKay HT, et al. Contraceptive efficacy of a novel spermicidal microbicide used with a diaphragm: a randomized controlled trial. Obstet Gynecol. 2007; 110(3):577-86.
12. Luchters S, Chersich MF, Jao I, et al. Acceptability of the diaphragm in Mombasa Kenya: a 6-month prospective study. Eur J Contracept Reprod Health Care. 2007;16:1-9.
13. Guest G, Johnson L, Burke H, et al. Changes in sexual behavior during a safety and feasibility trial of a microbicide/diaphragm combination: an integrated qualitative and quantitative analysis. AIDS Educ Prev. 2007;19(4):310-20.
14. Moon M, Khumalo-Sakutukwa G, Heiman J, Mbizvo M, Padian N. Vaginal microbicides for HIV/STI prevention in Zimbabwe: what key informants say. J Transcult Nurs. 2002;13(1):19-23.
15. Pool R, Whitworth JA, Green G, et al. An acceptability study of female-controlled methods of protection against HIV and STDs in south-western Uganda. Int J STD AIDS. 2000;11(3):162-7.
16. Behets F, Turner A, Van Damme K, et al. Acceptability and feasibility of continuous diaphragm use among sex workers in Madagascar. Sex Transm Infect. 2005;81(6):472-6.
17. Ramjee G, Gouws E, Andrews A, Myer L, Weber A. The acceptability of vaginal microbicide among South African men. Int Fam Plann Perspec. 2001;27(4):164-70.
18. Bird S, Harvey S, Maher J, Beckman L. Acceptability of an existing, female-controlled contraceptive method that could potentially protect against HIV: a comparison of diaphragm users and other method users. Women Health Iss. 2004;14(3):85-93.
19. Buck J, Kang MS, van der Straten A, et al. Barrier method preferences and perceptions among Zimbabwean women and their partners. AIDS Behav. 2005;9(4):1-8.
20. Harvey S, Bird S, Maher J, Beckman L. Who continues using the diaphragm and who doesn't: implications for the acceptability of female-controlled HIV prevention methods. Women Health Iss. 2003;13(5):185-93.
21. van der Straten A, Kang M, Posner S, et al. Predictors of diaphragm use as a potential sexually transmitted disease/HIV prevention method in Zimbabwe. Sex Transm Dis. 2005;32(1): 64-71.
22. Bentley ME, Fullem AM, Tolley EE, et al. Acceptability of a microbicide among women and their partners in a 4-country phase I trial. Am J Public Health. 2004;94(7):1159-64.
23. Coggins C, Blanchard K, Friedland B. Men's attitudes towards a potential vaginal microbicide in Zimbabwe, Mexico and the USA. Reprod Health Matters. 2000;8(15):132-41.
24. van de Wijgert J, Khumalo-Sakutukwa G, Coggins C, et al. Men's attitudes toward vaginal microbicides and microbicide trials in Zimbabwe. Int Fam Plan Perspec. 1999;25(1):15-20.
25. van der Straten A, Moore J, Napierala S, et al. Consistent use of a combination product versus a single product in a safety trial of the diaphragm and microbice in Harare, Zimbabwe. Contraception. 2008;77(6):435-43.
26. Minnis A, Shiboski S, Padian N. Barrier contraceptive method acceptability and choice are not reliable indicators of use. Sex Transm Dis. 2003;30(7):556-61.
27. Catania JA, Binson D, van der Straten A, Stone V. Methodological research on sexual behavior in the AIDS era. In: Rosen RC, Davis CM, Ruppel JHJ, editors. Annual review of sex research, vol. 6. Mt. Vernon, IA: Society for the Scientific Study of Sexuality; 1995. p. 77-125.
28. Mantell JE, Stein ZA, Susser I. Women in the time of AIDS: barriers, bargains, and benefits. AIDS Educ Prev. 2008;20(2): 91-106.
29. Philpott A, Knerr W, Maher D. Promoting protection and pleasure: amplifying the effectiveness of barriers against sexually transmitted infections and pregnancy. Lancet. 2006;368(9551): 2028-31.
30. Hammett TM, Mason TH, Joanis CL, et al. Acceptability of formulations and application methods for vaginal microbicides among drug-involved women: results of product trials in three cities. Sex Transm Dis. 2000;27(2):119-26.
31. Woodsong C. Covert use of topical microbicides: implications for acceptability and use. Int Fam Plan Perspec. 2004;30(2):94-8.
32. Woodsong C, Alleman P. Sexual pleasure, gender power and microbicide acceptability in Zimbabwe and Malawi. AIDS Educ Prev. 2008;20(2):171-87.
33. Montgomery E, Musara P, Chandipiswa A, et al. Safety of the Duet used continuously or pre-coitally in Zimbabwean women International AIDS society conference on HIV pathogenesis, treatment and prevention. Vol Cape Town, South Africa 2009.
34. van der Straten A, Cheng H, Moore J, et al. The use of the diaphragm instead of condoms in a phase III diaphragm trial. AIDS Behav. 2009;13:564-572.
35. van der Straten A, Shiboski S, Montgomery ET, et al. Patterns and predictors of adherence to diaphragm use in a phase III trial in sub-Saharan Africa: a trajectory analysis. J Acquire Immune Defic Syndr. 2009;50(4):419-26.
36. Weiss HA, Wasserheit JN, Barnabas RV, et al. Persisting with prevention: the importance of adherence for HIV prevention. Emerg Theme Epidemiol. 2008;2008(5):9.