(s)-armepavine from Chinese medicine improves experimental autoimmune crescentic glomerulonephritis

Rheumatology

Volumn 49, Issue 10, 2010, Pages 1840-1851

  Ka, Shuk Man ^a   Kuo, Yuh Chi ^b   Ho, Pay June ^a   Tsai, Pei Yi ^c   Hsu, Yu Juei ^a   Tsai, Wei Jern ^d   Lin, Yun Lian ^d   Shen, Chien Chang ^d   Chen, Ann ^a,c  

^a TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^b FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^c NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^d NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

Author keywords

(S) armepavine; Apoptosis; Crescent; Crescentic glomerulonephritis; Macrophage; Nelumbo nucifera; Nuclear factor B; T cell

Indexed keywords

ARMEPAVINE; AUTOANTIBODY; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 4; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; APOPTOSIS; ARTICLE; C57BL 6 MOUSE; CELL PROLIFERATION; CHINESE MEDICINE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG ISOLATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HISTOPATHOLOGY; IMMUNE DYSREGULATION; IMMUNOHISTOCHEMISTRY; KIDNEY DYSFUNCTION; MACROPHAGE MIGRATION INHIBITION; MEDICINAL PLANT; MOUSE; NELUMBO NUCIFERA; NONHUMAN; PLANT SEED; PRIORITY JOURNAL; PROTEINURIA; RAPIDLY PROGRESSIVE GLOMERULONEPHRITIS; SPLEEN; T LYMPHOCYTE; THERAPY EFFECT;

ALKALOIDS; ANIMALS; APOPTOSIS; BENZYLISOQUINOLINES; DISEASE MODELS, ANIMAL; DRUGS, CHINESE HERBAL; FEMALE; GLOMERULONEPHRITIS; MACROPHAGES; MEDICINE, CHINESE TRADITIONAL; MICE; MICE, INBRED C57BL; NELUMBO; NF-KAPPA B; T-LYMPHOCYTES;

EID: 77956861433     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/keq164     Document Type: Article

References (44)

1. Alpers C. The kidney. In: Kumar V, Cotran RS, Collins T, eds. Robbins and Cotran: pathologic basis of disease, 7th edition. Philadelphia: Saunders, 2005:976-8.
2. Isome M, Fujinaka H, Adhikary LP et al. Important role for macrophages in induction of crescentic anti-GBM glomerulonephritis in WKY rats. Nephrol Dial Transplant 2004;19:2997-3004.
3. Lan HY, Nikolic-Paterson DJ, Atkins RC. Involvement of activated periglomerular leukocytes in the rupture of Bowman's capsule and glomerular crescent progression in experimental glomerulonephritis. Lab Invest 1992;67: 743-51.
4. Lan HY, Nikolic-Paterson DJ, Mu W, Atkins RC. Local macrophage proliferation in the pathogenesis of glomerular crescent formation in rat anti-glomerular basement membrane (GBM) glomerulonephritis. Clin Exp Immunol 1997;110:233-40.
5. Kitching AR, Holdsworth SR, Tipping PG. Crescentic glomerulonephritis-a manifestation of a nephritogenic Th1 response? Histol Histopathol 2000;15:993-1003.
6. Lenda DM, Stanley ER, Kelley VR. Negative role of colony-stimulating factor-1 in macrophage, T cell, and B cell mediated autoimmune disease in MRL-Fas(lpr) mice. J Immunol 2004;173:4744-54.
7. Liu CP, Kuo YC, Shen CC et al. (S)-armepavine inhibits human peripheral blood mononuclear cell activation by regulating Itk and PLCgamma activation in a PI-3K-dependent manner. J Leukoc Biol 2007;81: 1276-86.
8. Liu CP, Tsai WJ, Shen CC et al. Inhibition of (S)-armepavine from Nelumbo nucifera on autoimmune disease of MRL/MpJ-lpr/lpr mice. Eur J Pharmacol 2006;531: 270-9.
9. Talukder MJ, Nessa J. Effect of Nelumbo nucifera rhizome extract on the gastrointestinal tract of rat. Bangladesh Med Res Counc Bull 1998;24:6-9.
10. Mukherjee PK, Saha K, Das J, Pa M, Saha BP. Studies on the anti-inflammatory activity of rhizomes of Nelumbo nucifera. Planta Med 1997;63:367-9.
11. Ka SM, Rifai A, Chen JH et al. Glomerular crescent-related biomarkers in a murine model of chronic graft versus host disease. Nephrol Dial Transplant 2006;21:288-98.
12. Ka SM, Sytwu HK, Chang DM, Hsieh SL, Tsai PY, Chen A. Decoy receptor 3 ameliorates an autoimmune crescentic glomerulonephritis model in mice. J Am Soc Nephrol 2007;18:2473-85.
13. Ka SM, Huang XR, Lan HY et al. Smad7 gene therapy ameliorates an autoimmune crescentic glomerulonephritis in mice. J Am Soc Nephrol 2007;18:1777-88.
14. Abbas A. Disease of immunity. In: Kumar V, Cotran RS, Collins T, eds. Robbins and Cotran: pathologic basis of disease. 7th edition. Philadelphia: Saunders, 2005:227.
15. Gleichmann E, Van Elven EH, Van der Veen JP. A systemic lupus erythematosus (SLE)-like disease in mice induced by abnormal T-B cell cooperation. Preferential formation of autoantibodies characteristic of SLE. Eur J Immunol 1982;12:152-9.
16. Choudhury A, Maldonado MA, Cohen PL, Eisenberg RA. The role of host CD4T cells in the pathogenesis of the chronic graft-versus-host model of systemic lupus erythematosus. J Immunol 2005;174:7600-9.
17. Van Elven EH, Rolink AG, Veen FV, Gleichmann E. Capacity of genetically different T lymphocytes to induce lethal graft-versus-host disease correlates with their capacity to generate suppression but not with their capacity to generate anti-F1 killer cells. A non-H-2 locus determines the inability to induce lethal graft-versus-host disease. J Exp Med 1981;153:1474-88.
18. Aguilar F, Gonzalez-Escribano MF, Sanchez-Roman J, Nunez-Roldan A. MCP-1 promoter polymorphism in Spanish patients with systemic lupus erythematosus. Tissue Antigens 2001;58:335-8.
19. Wada T, Furuichi K, Segawa-Takaeda C et al. MIP-1alpha and MCP-1 contribute to crescents and interstitial lesions in human crescentic glomerulonephritis. Kidney Int 1999; 56:995-1003.
20. Umland SP, Razac S, Nahrebne DK, Seymour BW. Effects of in vivo administration of interferon (IFN)-gamma, anti-IFN-gamma, or anti-interleukin-4 monoclonal antibodies in chronic autoimmune graft-versus-host disease. Clin Immunol Immunopathol 1992;63:66-73.
21. Wong CK, Ho CY, Li EK, Lam CW. Elevation of proinflammatory cytokine (IL-18, IL-17, IL-12) and Th2 cytokine (IL-4) concentrations in patients with systemic lupus erythematosus. Lupus 2000;9:589-93.
22. Masutani K, Akahoshi M, Tsuruya K et al. Predominance of Th1 immune response in diffuse proliferative lupus nephritis. Arthritis Rheum 2001;44:2097-106.
23. Uhm WS, Na K, Song GW et al. Cytokine balance in kidney tissue from lupus nephritis patients. Rheumatology 2003; 42:935-8.
24. Huang XR, Tipping PG, Apostolopoulos J et al. Mechanisms of T cell-induced glomerular injury in anti-glomerular basement membrane (GBM) glomerulonephritis in rats. Clin Exp Immunol 1997;109: 134-42.
25. Liu ZH, Chen SF, Zhou H, Chen HP, Li LS. Glomerular expression of C-C chemokines in different types of human crescentic glomerulonephritis. Nephrol Dial Transplant 2003;18:1526-34.
26. Chen S, Liu Z, Chen H, Zhou H, Wang J, Li L. Glomerular chemokine expression and the effect of steroid and cyclophosphamide pulse therapy in human crescentic glomerulonephritis. Chin Med J 2002;115: 1301-7.
27. Moutabarrik A, Nakanishi I, Zaid D et al. Interleukin-1-beta activation of cultured glomerular epithelial cells. Exp Nephrol 1994;2:196-204.
28. Yang N, Nikolic-Paterson DJ, Ng YY et al. Reversal of established rat crescentic glomerulonephritis by blockade of macrophage migration inhibitory factor (MIF): Potential role of MIF in regulating glucocorticoid production. Mol Med 1998;4:413-24.
29. Lan HY, Nikolic-Paterson DJ, Mu W, Vannice JL, Atkins RC. Interleukin-1 receptor antagonist halts the progression of established crescentic glomerulonephritis in the rat. Kidney Int 1995;47:1303-9.
30. Gaipl US, Kuhn A, Sheriff A et al. Clearance of apoptotic cells in human SLE. Curr Dir Autoimmun 2006;9: 173-87.
31. Goumenos DS, Kalliakmani P, Tsakas S, Papachristou E, Vlachojannis JG. Growth factors and apoptosis-related protein expression in human crescentic nephritis. Med Sci Monit 2008;14:BR243-8.
32. Licht R, Dieker JW, Jacobs CW, Tax WJ, Berden JH. Decreased phagocytosis of apoptotic cells in diseased SLE mice. J Autoimmun 2004;22:139-45.
33. Liu CC, Navratil JS, Sabatine JM, Ahearn JM. Apoptosis, complement and systemic lupus erythematosus: a mechanistic view. Curr Dir Autoimmun 2004;7:49-86.
34. Mevorach D. Systemic lupus erythematosus and apoptosis: a question of balance. Clin Rev Allergy Immunol 2003;25:49-60.
35. Hoffman RW. T cells in the pathogenesis of systemic lupus erythematosus. Clin Immunol 2004;113:4-13.
36. Nagy G, Koncz A, Perl A. T- and B-cell abnormalities in systemic lupus erythematosus. Crit Rev Immunol 2005;25: 123-40.
37. Burlingame RW, Rubin RL, Balderas RS, Theofilopoulos AN. Genesis and evolution of antichromatin autoantibodies in murine lupus implicates T-dependent immunization with self antigen. J Clin Invest 1993;91: 1687-96.
38. Tomita N, Morishita R, Lan HY et al. In vivo administration of a nuclear transcription factor-kappaB decoy suppresses experimental crescentic glomerulonephritis. J Am Soc Nephrol 2000;11:1244-52.
39. Jeruc J, Vizjak A, Rozman B, Ferluga D. Immunohistochemical expression of activated caspase-3 as a marker of apoptosis in glomeruli of human lupus nephritis. Am J Kidney Dis 2006;48:410-8.
40. Wagrowska-Danilewicz M, Danilewicz M. Apoptosis in lupus SLE-N IV and non-lupus mesangiocapillary glomerulonephritis type I MCGN. I. A comparative study. J Nephrol 1998;11:44-9.
41. Jow GM, Wu YC, Guh JH, Teng CM. Armepavine oxalate induces cell death on CCRF-CEM leukemia cell line through an apoptotic pathway. Life Sci 2004;75:549-57.
42. Watanabe-Fukunaga R, Brannan CI, Copeland NG, Jenkins NA, Nagata S. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 1992;356:314-7.
43. Xue C, Lan-Lan W, Bei C, Jie C, Wei-Hua F. Abnormal Fas/FasL and caspase-3-mediated apoptotic signaling pathways of T lymphocyte subset in patients with systemic lupus erythematosus. Cell Immunol 2006;239:121-8.
44. Dhir V, Singh AP, Aggarwal A, Naik S, Misra R. Increased T-lymphocyte apoptosis in lupus correlates with disease activity and may be responsible for reduced T-cell frequency: a cross-sectional and longitudinal study. Lupus 2009;18:785-91.