Recovery from liver disease in a Niemann-Pick type C mouse model

Journal of Lipid Research

Volumn 51, Issue 8, 2010, Pages 2372-2383

  Sayre, Naomi L ^a   Rimkunas, Victoria M ^a   Graham, Mark J ^b   Crooke, Rosanne M ^b   Liscum, Laura ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ISIS PHARMACEUTICALS   (United States)

Author keywords

ATP binding cassette G5; HMG CoA reductase; Liver X receptor; Lysosomal storage disease; Sterol responsive element binding protein 2

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CHOLESTEROL; NPC1 PROTEIN, MOUSE; PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BAGG ALBINO MOUSE; CELL DEATH; CHOLESTEROL METABOLISM; CONTROLLED STUDY; FEMALE; GENE DISRUPTION; GENE SILENCING; GENETIC TRANSCRIPTION; HEPATOMEGALY; HISTOPATHOLOGY; HOMEOSTASIS; LIPID STORAGE; LIVER CELL; LIVER DISEASE; LIVER FIBROSIS; LONG TERM CARE; MOUSE; NIEMANN PICK DISEASE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; APOPTOSIS; CELL PROLIFERATION; COMPLICATION; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; LIVER; LIVER CIRRHOSIS; LIVER DISEASES; MACROPHAGE; METABOLISM; PATHOLOGY; TIME;

ANIMALS; APOPTOSIS; BASE SEQUENCE; CELL PROLIFERATION; CHOLESTEROL; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HEPATOMEGALY; HOMEOSTASIS; LIVER; LIVER CIRRHOSIS; LIVER DISEASES; MACROPHAGES; MICE; NIEMANN-PICK DISEASE, TYPE C; OLIGONUCLEOTIDES, ANTISENSE; PHENOTYPE; PROTEINS; TIME FACTORS;

EID: 77956843961     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M007211     Document Type: Article

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