Hepatic stellate cell: A star cell in the liver

International Journal of Biochemistry and Cell Biology

Volumn 41, Issue 8-9, 2009, Pages 1639-1642

  Atzori, Luigi ^a   Poli, Giuseppe ^b   Perra, Andrea ^a  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

Author keywords

Extracellular matrix; Hepatic stellate cells; Liver fibrosis; Myofibroblasts

Indexed keywords

ANGIOTENSIN II;

ALCOHOLIC FATTY LIVER; CELL ACTIVATION; CELL FUNCTION; EXTRACELLULAR MATRIX; FATTY LIVER; HEPATITIS; HUMAN; IMMUNOREGULATION; LIVER BLOOD FLOW; LIVER CANCER; LIVER CARCINOGENESIS; LIVER CELL; LIVER DEVELOPMENT; LIVER FIBROSIS; LIVER REGENERATION; NONHUMAN; PORTAL HYPERTENSION; SHORT SURVEY; STELLATE CELL; XENOBIOTIC METABOLISM;

ANIMALS; HEPATIC STELLATE CELLS; HUMANS; LIVER;

EID: 67349165423     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2009.03.001     Document Type: Short Survey

References (27)

1. Bataller R., Ginès P., Nicolàs J.M., Görbig N., Garcia-Ramallo E., Gasull X., et al. Angiotensin II induces contraction and proliferation of human hepatic stellate cells. Gastroenterology 118 (2000) 1149-1156
2. Benyon R.C., and Arthur M.J.P. Extracellular matrix degradation and the role of hepatic stellate cells. Semin Liver Dis 21 (2001) 373-384
3. Casini A., Pellegrini G., Ceni E., Salzano R., Parola M., Robino G., et al. Human hepatic stellate cells express class I alcohol dehydrogenase and aldehyde dehydrogenase but not cytochrome P4502E1. J Hepatol 28 (1998) 40-45
4. Friedman S.L. Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. Physiol Rev 88 (2008) 125-172
5. Gerts A. On the origin of stellate cells: mesodermal, endodermal or neuro-ectodermal?. J Hepatol 40 (2004) 331-334
6. Giampieri M.P., Jezequel A.M., and Orlandi F. The lipocytes in normal human liver. Digestion 22 (1991) 165-169
7. Gressner A.M., and Weiskirchen R. Modern pathogenetic concepts on liver fibrosis suggest stellate cells and TGF-beta as major players and therapeutic targets. J Cell Biol Med 10 (2006) 76-99
8. Kiassov A.P., Van Eyken P., Van Pelt J.F., Depla E., Fevery J., Desmet V.J., et al. Desmin expressing non hematopoietic liver cells during rat liver development: an immunohistochemical and morphometric study. Differentiation 59 (1995) 253-258
9. Kordes C., Sawitza I., Muller-Marbach A., Ale-Agha N., Keitel V., Klonowski-Stumpe H., et al. CD133(+) hepatic stellate cells are progenitor cells. Biochem Biophys Res Commun 352 (2007) 410-417
10. Lee S.J., Friedman S.L., Whalen R., and Boyer T.D. Cellular sources of glutathione S-transferase P in primary cultured rat hepatocytes: localization by in situ hybridisation. Biochem J 299 (1994) 79-83
11. Martín-Vílchez S., Sanz-Cameno P., Rodríguez-Muñoz Y., Majano P.L., Molina-Jimenéz F., López-Cabrera M., et al. The hepatitis B virus X protein induces paracrine activation of human hepatic stellate cells. Hepatology 47 (2008) 1872-1883
12. Mengshol J.A., Golden-Mason L., and Rosen H.R. Mechanisms of disease: HCV-induced liver injury. Nat Clin Pract Gastroenterol Hepatol 4 (2007) 622-634
13. Notas G., Kisseleva T., and Brenner D. NK and NKT cellsin liver injury and fibrosis. Clin Immunol 130 (2009) 16-26
14. Ohata M., Lin M., Satre M., and Tsukamoto H. Diminished retinoic acid signaling in hepatic stellate cells in cholestatic liver fibrosis. Am J Physiol Gastrointest Liver Physiol 272 (1997) G589-G596
15. Parola M., Marra F., and Pinzani M. Myofibroblast-like cells and liver fibrogenesis: emerging concepts in a rapidly moving scenario. Mol Aspects Med 29 (2008) 58-66
16. Pinzani M., and Marra F. Cytokine receptors and signalling in hepatic stellate cells. Semin Liver Dis 21 (2001) 397-416
17. Poli G. Pathogenesis of liver fibrosis: role of oxidative stress. Mol Aspects Med 2 (2000) 49-98
18. Ramadori G., and Saile B. Mesenchymal cells in the liver-one cell type or two?. Liver 22 (2002) 283-294
19. Reeves H.L., Burt A.D., Wood S., and Day C.P. Hepatic stellate cell activation occurs in the absence of hepatitis in alcoholic liver disease and correlates with the severity of steatosis. J Hepatol 25 (1996) 677-683
20. Rockey D.C. Hepatic blood flow regulation by stellate cells in normal and injured liver. Semin Liver Dis 21 (2001) 337-350
21. Rubbia-Brandt L., Mentha G., Desmouliere A., Alto Costa A.M., Giostra E., Molas G., et al. Hepatic stellate cells reversibly express alpha-smooth muscle actin during acute hepaticischemia. Transplant Proc 29 (1997) 2390-2395
22. Schmitt-Graeff A., Jing R., Nitschke R., Desmouliere A., and Skalli O. Synemin expression is widespread in liver fibrosis and is induced in proliferating and malignant biliary epithelial cells. Hum Pathol 37 (2006) 1200-1210
23. Schwabe R.F., Bataller R., and Brenner D.A. Human hepatic stellate cells express CCR5 and RANTES to induce proliferation and migration. Am J Physiol Gastrointest Liver Physiol 285 (2003) G949-G958
24. Suskind D.L., and Muench M.O. Searching for common stem cells of the hepatic and hematopoietic systems in the human fetal liver: CD34 + cytokeratin7/8 + cells express markers for stellate cells. J Hepatol 40 (2004) 261-268
25. Wake K. Structure of the sinusoidal wall in the liver. In: Wisse E., Knook D.L., and Wake K. (Eds). Cells of the hepatic sinusoid (1995), The Kupffer Cell Foundation, Leiden pp. 241-246
26. Winau F., Hegasy G., Weiskirchen R., Weber S., Cassan C., Sieling P.A., et al. Ito cells are liver-resident antigen-presenting cells for activating T cell responses. Immunity 26 (2007) 9-10
27. Wirz W., Antoine M., Tag C.G., Gressner A.M., Kor T., Hellerbrand C., et al. Hepatic stellate cells display a functional vascular smooth muscle cell phenotype in a three-dimensional co-culture model with endothelial cells. Differentiation 76 (2008) 784-794