Detecting low-level synthesis impurities in modified phosphorothioate oligonucleotides using liquid chromatography-high resolution mass spectrometry

International Journal of Mass Spectrometry

Volumn 304, Issue 2-3, 2011, Pages 98-104

  Nikcevic, Irena ^a   Wyrzykiewicz, Tadeusz K ^b   Limbach, Patrick A ^a  

^a UNIVERSITY OF CINCINNATI   (United States)

^b Girindus America Inc   (United States)

Author keywords

Accurate mass measurement; High resolution mass spectrometry; LC FTMS; Phosphorothioatediesters; Synthetic oligonucleotides

Indexed keywords

EID: 77956792381     PISSN: 13873806     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijms.2010.06.001     Document Type: Article

References (31)

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