Sensitivity to the satiating effects of exendin 4 is decreased in obesity-prone Osborne-Mendel rats compared to obesity-resistant S5B/Pl rats

International Journal of Obesity

Volumn 34, Issue 9, 2010, Pages 1427-1433

  Primeaux, S D ^a   Barnes, M J ^a   Braymer, H D ^a   Bray, G A ^a  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

Author keywords

exendin 4; GLP 1; High fat diet; obesity prone; obesity resistant; preproglucagon

Indexed keywords

EXENDIN 4; GLUCAGON LIKE PEPTIDE 1; MESSENGER RNA; PREPROGLUCAGON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG SENSITIVITY; FOOD INTAKE; GENE EXPRESSION; ILEUM; LIPID DIET; LOW FAT DIET; MALE; NONHUMAN; OBESITY; OSBORNE MENDEL RAT; OVERNUTRITION; PRIORITY JOURNAL; RAT; RAT STRAIN; S5B PI RAT; SATIETY; WEIGHT GAIN;

ANIMALS; DIETARY FATS; ENERGY INTAKE; GENE EXPRESSION REGULATION; GLUCAGON-LIKE PEPTIDE 1; MALE; OBESITY; PEPTIDES; PROGLUCAGON; RATS; RNA, MESSENGER; SATIATION; VENOMS; WEIGHT GAIN;

RATTUS;

EID: 77956710116     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2010.78     Document Type: Article

References (32)

1. Barnes MJ, Holmes G, Primeaux SD, York DA, Bray GA. Increased expression of mu opioid receptors in animals susceptible to diet-induced obesity. Peptides 2006; 27: 3292-3298.
2. Greenberg D, McCaffery J, Potack JZ, Bray GA, York DA. Differential satiating effects of fats in the small intestine of obesity-resistant and obesity-prone rats. Physiol Behav 1999; 66: 621-626.
3. Ishihara Y, White CL, Kageyama H, Kageyama A, York DA, Bray GA. Effects of diet and time of the day on serum and CSF leptin levels in Osborne-Mendel and S5B/Pl rats. Obes Res 2004; 12: 1067-1076.
4. Liu X, York DA, Bray GA. Regulation of ghrelin gene expression in stomach and feeding response to a ghrelin analogue in two strains of rats. Peptides 2004; 25: 2171-2177.
5. Petrescu O, Cheema AF, Fan X, Bradbury MW, Berk PD. Differences in adipocyte long chain fatty acid uptake in Osborne-Mendel and S5B/Pl rats in response to high-fat diets. Int J Obes 2008; 32: 853-862.
6. Pittman D, Smith KR, Crawley ME, Corbin CH, Hansen DR, Watson KJ et al. Orosensory detection of fatty acids by obesity-prone and obesity-resistant rats: strain and sex differences. Chem Senses 2008; 33: 449-460.
7. Primeaux SD, Barnes MJ, Bray GA. Olfactory bulbectomy increases food intake and hypothalamic neuropeptide Y in obesity-prone, but not obesity-resistant rats. Behav Brain Res 2007; 180: 190-196.
8. White CL, Ishihara Y, York DA, Bray GA. Effect of meta- chlorophenylpiperazine and cholecystokinin on food intake of Osborne-Mendel and S5B/Pl rats. Obesity 2007; 15: 624-631.
9. Chaudhri O, Bloom SR. Gastrointestinal hormones regulating appetite. Philos Trans R Soc Lond B Biol Sci 2006; 361: 1187-1209.
10. Heijboer AC, Piji H, van den Hoek AM, Havekes LM, Romijn JA, Corssmit EP. Gut-brain axis: regulation of glucose metabolism. J Neuroendocrinol 2006; 18: 883-894.
11. Moran TH. Gut peptide signaling in the control of food intake. Obesity 2006; 14 (Suppl 5): 250S-253S.
12. Moran TH. Gut peptides in the control of food intake. Int J Obes 2009; 33: S7-S10.
13. Strader AD, Woods SC. Gastrointestinal hormones and food intake. Gastroenterology 2005; 128: 175-191.
14. Wren AM, Bloom SR. Gut hormones and appetite control. Gastroenterology 2007; 132: 2116-2130.
15. Beglinger C, Degen C. Gastrointestinal satiety signals in humansFphysiologic roles for GLP-1 and PYY? Physiol Behav 2006; 89: 460-464.
16. Druce MR, Small CJ, Bloom SR. Minireview: gut peptides regulating satiety. Endocrinology 2004; 145: 2660-2665.
17. Holst JJ. Glucagonlike peptide 1: a newly discovered gastrointestinal hormone. Gastroenterology 1994; 107: 1848-1855.
18. Moran TH, Dailey MJ. Minireview: gut peptides: targets for antiobesity drug development? Endocrinology 2009; 150: 2526-2530.
19. Naslund E, Hellstrom PM. Glucagon-like peptide-1 in the pathogenesis of obesity. Drug News Perspect 1998; 11: 92-97.
20. Williams DL, Baskin DG, Schwartz MW. Leptin regulation of the anorexic response to glucagon-like peptide-1 receptor stimulation. Diabetes 2006; 55: 3387-3393.
21. Nakagawa A, Satake H, Nakabayashi H, Nishizawa M, Furuya K, Nakano S et al. Receptor gene expression of glucagon-like peptide-1, but not glucose-dependent insulinotropic poly-peptide, in rat nodose ganglion cells. Auton Neurosci 2004; 110: 36-43.
22. Shughrue PJ, Lane MV, Merchenthaler I. Glucagon-like peptide-1 receptor (GLP1-R) mRNA in the rat hypothalamus. Endocrinology 1996; 137: 5159-5162.
23. Turton MD, O'Shea D, Gunn I, Beak SA, Edwards CM, Meeran K et al. A role for glucagon-like peptide-1 in the central regulation of feeding. Nature 1996; 379: 69-72. (Pubitemid 26008136)
24. Davis HR, Mullins DE, Pines JM, Hoos LM, France CF, Compton DS et al. Effect of chronic central administration of glucagon-like peptide 1 (7-36) amide on food consumption and body weight in normal and obese rats. Obes Res 1998; 6: 147-156.
25. Lin L, Chen J, York DA. Chronic ICV enterostatin preferentially reduced fat intake and lowered body weight. Peptides 1997; 18: 657-661.
26. Primeaux SD, York DA, Bray GA. Neuropeptide Y administration into the amygdala alters high fat food intake. Peptides 2006; 27: 1644-1651.
27. Primeaux SD, Blackmon C, Barnes MJ, Braymer HD, Bray GA. Central administration of the RFamide peptides, QRFP-26 and QRFP-43, increases high fat food intake in rats. Peptides 2008; 29: 1994-2000.
28. Drucker DJ. Minireview: the glucagon-like peptides. Endocrinology 2001; 142: 521-527.
29. Lopez LC, Frazier ML, Su CJ, Kumar A, Saunders GF. Mammalian pancreatic preproglucagon contains three glucagon-related pep-tides. Proc Natl Acad Sci USA 1983; 80: 5485-5489.
30. Tang-Christensen M, Vrang N, Larsen PJ. Glucagon-like peptide containing pathways in the regulation of feeding behaviour. Int J Obes Relat Metab Disord 2001; 25 (Suppl 5): S42-S47.
31. Holst JJ. Glucagon-like peptide 1 (GLP-1): an intestinal hormone, signalling nutritional abundance, with an unusual therapeutic potential. Trends Endocrinol Metab 1999; 10: 229-235.
32. Wynne K, Stanley S, McGowan B, Bloom S. Appetite control. J Endocrinol 2005; 184: 291-318.