Challenges in synthetically designing mammalian circadian clocks

Current Opinion in Biotechnology

Volumn 21, Issue 4, 2010, Pages 556-565

  Susaki, Etsuo A ^a,b   Stelling, Jörg ^c   Ueda, Hiroki R ^a,d,e  

^a RIKEN Center for Biosystems Dynamics Research   (Japan)

^b JAPAN SOCIETY FOR THE PROMOTION OF SCIENCE   (Japan)

^c ETH ZURICH   (Switzerland)

^d OSAKA UNIVERSITY   (Japan)

^e KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL CLOCK; BIOLOGICAL COMPONENTS; CIRCADIAN CLOCK; CIRCADIAN SYSTEM; CLINICAL PROBLEMS; DESIGN PRINCIPLES; DYNAMIC BEHAVIORS; DYNAMIC SYSTEMS; POST-TRANSCRIPTIONAL; RATIONAL SYNTHESIS; SLEEP DISORDERS; SUPRACHIASMATIC NUCLEUS; SYNTHETIC BIOLOGY;

BIOLOGICAL SYSTEMS; CONTROL SYSTEM SYNTHESIS; MAMMALS;

CLOCKS;

PROTEIN BMAL1; TRANSCRIPTION FACTOR CLOCK;

BIOENGINEERING; BIOLOGICAL RHYTHM; BRAIN FUNCTION; CIRCADIAN RHYTHM; CIRCADIAN RHYTHM SLEEP DISORDER; HUMAN; HYPOTHALAMUS; MAMMAL; METABOLIC REGULATION; MOLECULAR CLOCK; MOLECULAR DYNAMICS; MOLECULAR MODEL; NEGATIVE FEEDBACK; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NONHUMAN; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROMOTER REGION; REGULATORY MECHANISM; REVIEW; SLEEP WAKING CYCLE; SUPRACHIASMATIC NUCLEUS; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

ANIMALS; CIRCADIAN CLOCKS; MAMMALS; SYSTEMS BIOLOGY; TRANSCRIPTION, GENETIC;

MAMMALIA;

EID: 77956647457     PISSN: 09581669     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.copbio.2010.07.011     Document Type: Review

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