Activity-based selection of HIV-1 reverse transcriptase variants with decreased polymerization fidelity

Biological Chemistry

Volumn 391, Issue 6, 2010, Pages 665-674

  Stumpp, Sascha N ^a   Heyn, Bianca ^a   Brakmann, Susanne ^a  

^a TU DORTMUND UNIVERSITY   (Germany)

Author keywords

Directed evolution; DNA RNA replication; Mutagenesis; Reverse transcriptase; Viruses

Indexed keywords

RNA DIRECTED DNA POLYMERASE; REVERSE TRANSCRIPTASE, HUMAN IMMUNODEFICIENCY VIRUS 1; VIRUS DNA; VIRUS RNA;

ARTICLE; DIRECTED MOLECULAR EVOLUTION; DNA REPLICATION; FRAMESHIFT MUTATION; GENETIC SELECTION; HUMAN IMMUNODEFICIENCY VIRUS 1; MUTATION RATE; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN POLYMERIZATION; RNA REPLICATION; SITE DIRECTED MUTAGENESIS; VIRUS MUTATION; VIRUS REPLICATION; CHEMISTRY; GENETICS; METABOLISM;

HUMAN IMMUNODEFICIENCY VIRUS 1;

DIRECTED MOLECULAR EVOLUTION; DNA, VIRAL; HIV REVERSE TRANSCRIPTASE; MUTAGENESIS, SITE-DIRECTED; RNA, VIRAL;

EID: 77956638741     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2010.067     Document Type: Article

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