Establishment of steady-state metabolism of ethanol in perfused rat liver: The quantitative analysis using kinetic mechanism-based rate equations of alcohol dehydrogenase

Alcohol

Volumn 44, Issue 6, 2010, Pages 541-551

  Yao, Chung Tay ^a,b   Lai, Ching Long ^c   Hsieh, Hsiu Shan ^b   Chi, Chin Wen ^d   Yin, Shih Jiun ^b  

^a CATHAY GENERAL HOSPITAL   (Taiwan)

^b NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^c CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^d TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Acetaldehyde; Acetate; Alcohol dehydrogenase; Aldehyde dehydroenase; Rat liver perfusion; Steady state metabolism of ethanol

Indexed keywords

4 METHYLPYRAZOLE; ACETALDEHYDE; ACETIC ACID; ALCOHOL; ALCOHOL DEHYDROGENASE; ENZYME INHIBITOR; ISOBUTYRAMIDE; LACTIC ACID; PYRUVIC ACID; UNCLASSIFIED DRUG;

ALCOHOL METABOLISM; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVITY; ENZYME KINETICS; EX VIVO STUDY; LIVER BLOOD FLOW; LIVER PERFUSION; MALE; METABOLIC RATE; METABOLITE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; QUALITATIVE RESEARCH; QUANTITATIVE ANALYSIS; RAT; SPRAGUE DAWLEY RAT; STEADY STATE;

ACETALDEHYDE; ALCOHOL DEHYDROGENASE; ANIMALS; BINDING, COMPETITIVE; ENZYME INHIBITORS; ETHANOL; KINETICS; LIVER; MALE; NAD; PERFUSION; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 77956629392     PISSN: 07418329     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.alcohol.2010.07.002     Document Type: Article

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