Clinical and diagnostic implications of monoclonal B-cell lymphocytosis

Best Practice and Research: Clinical Haematology

Volumn 23, Issue 1, 2010, Pages 61-69

  Rawstron, Andy C ^a,b   Hillmen, Peter ^a  

^a ST JAMES S INSTITUTE OF ONCOLOGY   (United Kingdom)

^b UNIVERSITY OF YORK   (United Kingdom)

Author keywords

Chronic Lymphocytic Leukaemia (CLL); Monoclonal B cell Lymphocytosis (MBL)

Indexed keywords

B LYMPHOCYTE RECEPTOR; CD23 ANTIGEN; CD5 ANTIGEN; IMMUNOGLOBULIN HEAVY CHAIN;

ALLOTRANSPLANTATION; ANEMIA; AUTOIMMUNE HEMOLYTIC ANEMIA; B LYMPHOCYTE; BLOOD TRANSFUSION; BONE MARROW DEPRESSION; BONE MARROW EXAMINATION; CHROMOSOME 11Q; CHROMOSOME 13Q; CHROMOSOME 17P; CHROMOSOME ABERRATION; CHROMOSOME DELETION; CHROMOSOME DELETION 13; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL ASSESSMENT; CLINICAL PRACTICE; CYTOPENIA; DIAGNOSTIC PROCEDURE; DISEASE ASSOCIATION; DISEASE CLASSIFICATION; DISEASE COURSE; GENE MUTATION; GERM LINE; HLA MATCHING; HUMAN; IMMUNOGLOBULIN VARIABLE REGION; LYMPHADENOPATHY; LYMPHOCYTE COUNT; LYMPHOCYTOSIS; LYMPHOMA; MONOCLONAL B CELL LYMPHOCYTOSIS; PATHOPHYSIOLOGY; PATIENT MONITORING; PHENOTYPE; PHYSICAL EXAMINATION; PRIORITY JOURNAL; REVIEW; SCREENING TEST; SOMATIC HYPERMUTATION; SPLENOMEGALY; THROMBOCYTOPENIA; TREATMENT INDICATION; TRISOMY 12;

B-LYMPHOCYTES; HUMANS; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; LYMPHOCYTOSIS;

EID: 77956625437     PISSN: 15216926     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.beha.2010.02.002     Document Type: Review

References (31)

1. P. Abrisqueta, A. Pereira, and C. Rozman Improving survival in patients with chronic lymphocytic leukemia (1980-2008): the Hospital Clinic of Barcelona experience Blood 114 10 2009 Sep 3 2044 2050
2. S. Molica, and D. Levato What is changing in the natural history of chronic lymphocytic leukemia? Haematologica 86 1 2001 8 12
3. T.D. Shanafelt, D. Bowen, and C. Venkat Quality of life in chronic lymphocytic leukemia: an international survey of 1482 patients Br J Haematol 139 2 2007 Oct 255 264
4. G.E. Marti, A.C. Rawstron, and P. Ghia Diagnostic criteria for monoclonal B-cell lymphocytosis Br J Haematol 130 3 2005 325 332
5. P. Ghia, G. Prato, and C. Scielzo Monoclonal CD5+ and CD5-B-lymphocyte expansions are frequent in the peripheral blood of the elderly Blood 103 6 2004 2337 2342
6. A.C. Rawstron, M.J. Green, and A. Kuzmicki Monoclonal B lymphocytes with the characteristics of 'indolent' chronic lymphocytic leukemia are present in 3.5% of adults with normal blood counts Blood 100 2 2002 635 639
7. W.G. Nieto, J. Almeida, and A. Romero Increased frequency (12%) of circulating CLL-like B-cell clones in healthy individuals using a high-sensitive multicolor flow cytometry approach Blood 2009 [Internet]. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db= PubMed&dopt=Citation&list-uids=19420353
8. A.C. Rawstron, F. Bennett, and P. Hillmen The biological and clinical relationship between CD5+23+ monoclonal B-cell lymphocytosis and chronic lymphocytic leukaemia Br J Haematol 139 5 2007 724 729
9. A.C. Rawstron, F.L. Bennett, and S.J. O'Connor Monoclonal B-cell lymphocytosis and chronic lymphocytic leukemia N Engl J Med 359 6 2008 575 583
10. T.D. Shanafelt, N.E. Kay, and G. Jenkins B-cell count and survival: differentiating chronic lymphocytic leukemia from monoclonal B-cell lymphocytosis based on clinical outcome Blood 113 18 2009 Apr 30 4188 4196
11. K. Stamatopoulos, C. Belessi, and C. Moreno Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: pathogenetic implications and clinical correlations Blood 109 1 2007 259 270
12. A. Dagklis, C. Fazi, and C. Sala The immunoglobulin gene repertoire of low-count chronic lymphocytic leukemia (CLL)-like monoclonal B lymphocytosis is different from CLL: diagnostic implications for clinical monitoring Blood 114 1 2009 26 32
13. S.S. Fung, K.L. Hillier, and C.S. Leger Clinical progression and outcome of patients with monoclonal B-cell lymphocytosis Leuk Lymphoma 48 6 2007 1087 1091
14. C.S. Mulligan, M.E. Thomas, and S.P. Mulligan Monoclonal B-cell lymphocytosis and chronic lymphocytic leukemia N Engl J Med 359 19 2008 2065 2066 author reply 2066
15. T.D. Shanafelt, N.E. Kay, and K.G. Rabe Brief report: natural history of individuals with clinically recognized monoclonal B-cell lymphocytosis compared with patients with Rai 0 chronic lymphocytic leukemia J Clin Oncol 27 24 2009 Aug 20 3959 3963
16. D. Rossi, E. Sozzi, and A. Puma The prognosis of clinical monoclonal B cell lymphocytosis differs from prognosis of Rai 0 chronic lymphocytic leukaemia and is recapitulated by biological risk factors Br J Haematol 2009 [Internet]. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd= Retrieve&db=PubMed&dopt=Citation&list-uids=19438485
17. T.D. Shanafelt Predicting clinical outcome in CLL: how and why Hematology Am Soc Hematol Educ Program 2009 421 429
18. A.C. Rawstron, R.A. Jones, and C. Ferguson Outreach monitoring service for patients with indolent B-cell and plasma cell disorders: a UK experience Br J Haematol 139 5 2007 845 848
19. J.L. Herrick, T.D. Shanafelt, and N.E. Kay Monoclonal B-cell lymphocytosis (MBL): A bone marrow study of an indolent form of chronic lymphocytic leukemia (CLL) Mod Pathol 21 2008 1173
20. J.M. Rachel, M.L. Zucker, and C.M. Fox Monoclonal B-cell lymphocytosis in blood donors Br J Haematol 139 5 2007 832 836
21. G.E. Marti, P. Carter, and F. Abbasi B-cell monoclonal lymphocytosis and B-cell abnormalities in the setting of familial B-cell chronic lymphocytic leukemia Cytometry B Clin Cytom 52 1 2003 1 12
22. A.C. Rawstron, M.R. Yuille, and J. Fuller Inherited predisposition to CLL is detectable as subclinical monoclonal B-lymphocyte expansion Blood 100 7 2002 2289 2290
23. R. de Tute, M. Yuille, and D. Catovsky Monoclonal B-cell lymphocytosis (MBL) in CLL families: substantial increase in relative risk for young adults Leukemia 20 4 2006 728 729
24. I. Del Giudice, F.R. Mauro, and M.S. De Propris Identification of monoclonal B-cell lymphocytosis among sibling transplant donors for chronic lymphocytic leukemia patients Blood 114 13 2009 Sep 24 2848 2849
25. D.M. Matos, S.J. Ismael, and C.A. Scrideli Monoclonal B-cell lymphocytosis in first-degree relatives of patients with sporadic (non-familial) chronic lymphocytic leukaemia Br J Haematol 147 3 2009 Nov 339 346
26. N.M. Hardy, C. Grady, and R. Pentz Bioethical considerations of monoclonal B-cell lymphocytosis: donor transfer after haematopoietic stem cell transplantation Br J Haematol 139 5 2007 824 831
27. F. Caligaris-Cappio, and P. Ghia Novel insights in chronic lymphocytic leukemia: are we getting closer to understanding the pathogenesis of the disease? J Clin Oncol 26 27 2008 Sep 20 4497 4503
28. N.S. Majhail Old and new cancers after hematopoietic-cell transplantation Hematology Am Soc Hematol Educ Program 2008 142 149
29. D. Amato, D.G. Oscier, and Z. Davis Cytogenetic aberrations and immunoglobulin VH gene mutations in clinically benign CD5- monoclonal B-cell lymphocytosis Am J Clin Pathol 128 2 2007 Aug 333 338
30. A.C. Rawstron, N. Villamor, and M. Ritgen International standardized approach for flow cytometric residual disease monitoring in chronic lymphocytic leukaemia Leukemia 21 5 2007 May 956 964
31. S. Swerdlow, E. Campo, and N. Harris WHO classification of tumours of haematopoietic and lymphoid tissues 2008 WHO Press