Mitochondrial import of PKC is mediated by HSP90: A role in cardioprotection from ischaemia and reperfusion injury

Cardiovascular Research

Volumn 88, Issue 1, 2010, Pages 83-92

  Budas, Grant R ^a   Churchill, Eric N ^a   Disatnik, Marie Hélne ^a   Sun, Lihan ^a   Mochly Rosen, Daria ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Heat shock protein 90; Ischaemia reperfusion; Mitochondria; Protein kinase C epsilon; Protein protein interaction

Indexed keywords

7 AMINO ACID PEPTIDE ACTIVATOR; ALDEHYDE DEHYDROGENASE ISOENZYME 2; AMINO ACID; HEAT SHOCK PROTEIN 90; PROTEIN KINASE C EPSILON; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG; ALDEHYDE DEHYDROGENASE; ALDH2 PROTEIN, RAT; CELL RECEPTOR; ENZYME ACTIVATOR; MITOCHONDRIAL PROTEIN; OLIGOPEPTIDE; PRKCE PROTEIN, RAT; TOM20 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL FRACTIONATION; CELL PERMEABILIZATION; CELL PROTECTION; CONTROLLED STUDY; CYTOSOL; EX VIVO STUDY; HEART INFARCTION; HEART INJURY; HEART PROTECTION; HUMAN; HUMAN CELL; IMMUNOGOLD ELECTRON MICROSCOPY; ISCHEMIA; MALE; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; NECROSIS; NONHUMAN; NUCLEAR IMPORT; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; RAT; REPERFUSION INJURY; SEQUENCE HOMOLOGY; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; CONVALESCENCE; DISEASE MODEL; DRUG DESIGN; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; HEART CONTRACTION; HEART MITOCHONDRION; HEART MUSCLE; METABOLISM; MOLECULAR GENETICS; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION; PROTEIN BINDING; SEQUENCE ALIGNMENT; WISTAR RAT;

ALDEHYDE DEHYDROGENASE; AMINO ACID SEQUENCE; ANIMALS; CYTOPROTECTION; DISEASE MODELS, ANIMAL; DRUG DESIGN; ENZYME ACTIVATION; ENZYME ACTIVATORS; HSP90 HEAT-SHOCK PROTEINS; HUMANS; MALE; MITOCHONDRIA, HEART; MITOCHONDRIAL MEMBRANES; MITOCHONDRIAL PROTEINS; MOLECULAR SEQUENCE DATA; MYOCARDIAL CONTRACTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NECROSIS; OLIGOPEPTIDES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN KINASE C-EPSILON; PROTEIN TRANSPORT; RATS; RATS, WISTAR; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECOVERY OF FUNCTION; SEQUENCE ALIGNMENT;

EID: 77956596656     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvq154     Document Type: Article

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