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Volumn 116, Issue 10, 2010, Pages 1747-1754

High VEGFC expression is associated with unique gene expression profiles and predicts adverse prognosis in pediatric and adult acute myeloid leukemia

Author keywords

[No Author keywords available]

Indexed keywords

VASCULOTROPIN C;

EID: 77956587147     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-03-270991     Document Type: Article
Times cited : (84)

References (53)
  • 2
    • 0030118083 scopus 로고    scopus 로고
    • A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases
    • Joukov V, Pajusola K, Kaipainen A, et al. A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases. EMBO J. 1996;15(2):290-298.
    • (1996) EMBO J , vol.15 , Issue.2 , pp. 290-298
    • Joukov, V.1    Pajusola, K.2    Kaipainen, A.3
  • 3
    • 0033604614 scopus 로고    scopus 로고
    • Signaling via vascular endothelial growth factor receptors
    • Petrova TV, Makinen T, Alitalo K. Signaling via vascular endothelial growth factor receptors. Exp Cell Res. 1999;253(1):117-130.
    • (1999) Exp Cell Res , vol.253 , Issue.1 , pp. 117-130
    • Petrova, T.V.1    Makinen, T.2    Alitalo, K.3
  • 4
    • 0034650802 scopus 로고    scopus 로고
    • Regulation of angiogenesis via vascular endothelial growth factor receptors
    • Veikkola T, Karkkainen M, Claesson-Welsh L, et al. Regulation of angiogenesis via vascular endothelial growth factor receptors. Cancer Res. 2000;60(2):203-212. (Pubitemid 30070735)
    • (2000) Cancer Research , vol.60 , Issue.2 , pp. 203-212
    • Veikkola, T.1    Karkkainen, M.2    Claesson-Welsh, L.3    Alitalo, K.4
  • 5
    • 0030923575 scopus 로고    scopus 로고
    • Expression of FLT4 and its ligand VEGF-C in acute myeloid leukemia
    • Fiedler W, Graeven U, Ergun S, et al. Expression of FLT4 and its ligand VEGF-C in acute myeloid leukemia. Leukemia. 1997;11(8):1234-1237.
    • (1997) Leukemia , vol.11 , Issue.8 , pp. 1234-1237
    • Fiedler, W.1    Graeven, U.2    Ergun, S.3
  • 6
    • 0037085765 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF)-C signaling through FLT-4 (VEGFR-3) mediates leukemic cell proliferation, survival, and resistance to chemotherapy
    • DOI 10.1182/blood.V99.6.2179
    • Dias S, Choy M, Alitalo K, et al. Vascular endothelial growth factor (VEGF)-C signaling through FLT-4 (VEGFR-3) mediates leukemic cell proliferation, survival, and resistance to chemotherapy. Blood. 2002;99(6):2179-2184. (Pubitemid 34525504)
    • (2002) Blood , vol.99 , Issue.6 , pp. 2179-2184
    • Dias, S.1    Choy, M.2    Alitalo, K.3    Rafii, S.4
  • 7
    • 38949171393 scopus 로고    scopus 로고
    • Endogenous vascular endothelial growth factor-C expression is associated with decreased drug responsiveness in childhood acute myeloid leukemia
    • de Jonge HJ, Weidenaar AC, ter Elst A, et al. Endogenous vascular endothelial growth factor-C expression is associated with decreased drug responsiveness in childhood acute myeloid leukemia. Clin Cancer Res. 2008;14(3):924-930.
    • (2008) Clin Cancer Res , vol.14 , Issue.3 , pp. 924-930
    • De Jonge, H.J.1    Weidenaar, A.C.2    Ter Elst, A.3
  • 9
    • 0042967809 scopus 로고    scopus 로고
    • Effect of priming with granulocyte colony-stimulating factor on the outcome of chemotherapy for acute myeloid leukemia
    • Lowenberg B, van Putten W, Theobald M, et al. Effect of priming with granulocyte colony-stimulating factor on the outcome of chemotherapy for acute myeloid leukemia. N Engl J Med. 2003;349(8):743-752.
    • (2003) N Engl J Med , vol.349 , Issue.8 , pp. 743-752
    • Lowenberg, B.1    Van Putten, W.2    Theobald, M.3
  • 10
    • 11144358126 scopus 로고    scopus 로고
    • The value of fludarabine in addition to ARA-C and G-CSF in the treatment of patients with high-risk myelodysplastic syndromes and AML in elderly patients
    • Ossenkoppele GJ, Graveland WJ, Sonneveld P, et al. The value of fludarabine in addition to ARA-C and G-CSF in the treatment of patients with high-risk myelodysplastic syndromes and AML in elderly patients. Blood. 2004;103(8):2908-2913.
    • (2004) Blood , vol.103 , Issue.8 , pp. 2908-2913
    • Ossenkoppele, G.J.1    Graveland, W.J.2    Sonneveld, P.3
  • 11
    • 70449475104 scopus 로고    scopus 로고
    • AML at older age: Age related gene expression profiles reveal a paradoxical down-regulation of p16INK4A mRNA with prognostic significance
    • de Jonge HJ, de Bont ES, Valk PJ, et al. AML at older age: age related gene expression profiles reveal a paradoxical down-regulation of p16INK4A mRNA with prognostic significance. Blood. 2009;114(14):2869-2877.
    • (2009) Blood , vol.114 , Issue.14 , pp. 2869-2877
    • De Jonge, H.J.1    De Bont, E.S.2    Valk, P.J.3
  • 12
    • 11144358111 scopus 로고    scopus 로고
    • Prognostically useful gene-expression profiles in acute myeloid leukemia
    • Valk PJ, Verhaak RG, Beijen MA, et al. Prognostically useful gene-expression profiles in acute myeloid leukemia. N Engl J Med. 2004;350(16):1617-1628.
    • (2004) N Engl J Med , vol.350 , Issue.16 , pp. 1617-1628
    • Valk, P.J.1    Verhaak, R.G.2    Beijen, M.A.3
  • 13
    • 77953291051 scopus 로고    scopus 로고
    • Identification of gene expression signatures accurately predicting cytogenetic subtypes in pediatric acute myeloid leukemia
    • [abstract]. Abstract 1509
    • Balgobind BV, van den Heuvel-Eibrink MM, Menezes RX, et al. Identification of gene expression signatures accurately predicting cytogenetic subtypes in pediatric acute myeloid leukemia [abstract]. Blood. 2008;112(11):Abstract 1509
    • (2008) Blood , vol.112 , Issue.11
    • Balgobind, B.V.1    Van Den Heuvel-Eibrink, M.M.2    Menezes, R.X.3
  • 14
    • 34247325560 scopus 로고    scopus 로고
    • Results of a HOVON/SAKK donor versus nodonor analysis of myeloablative HLA-identical sibling stem cell transplantation in first remission acute myeloid leukemia in young and middle-aged adults: Benefits for whom?
    • Cornelissen JJ, van Putten WL, Verdonck LF, et al. Results of a HOVON/SAKK donor versus nodonor analysis of myeloablative HLA-identical sibling stem cell transplantation in first remission acute myeloid leukemia in young and middle-aged adults: benefits for whom? Blood. 2007;109(9):3658-3666.
    • (2007) Blood , vol.109 , Issue.9 , pp. 3658-3666
    • Cornelissen, J.J.1    Van Putten, W.L.2    Verdonck, L.F.3
  • 15
    • 0032188805 scopus 로고    scopus 로고
    • The importance of diagnostic cytogenetics on outcome in AML: Analysis of 1,612 patients entered into the MRC AML 10 trial
    • The Medical Research Council Adult and Children's Leukaemia Working Parties
    • Grimwade D, Walker H, Oliver F, et al. The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties. Blood. 1998;92(7):2322-2333.
    • (1998) Blood , vol.92 , Issue.7 , pp. 2322-2333
    • Grimwade, D.1    Walker, H.2    Oliver, F.3
  • 16
    • 33845512736 scopus 로고    scopus 로고
    • Various distinctive cytogenetic abnormalities in patients with acute myeloid leukaemia aged 60 years and older express adverse prognostic value: Results from a prospective clinical trial
    • DOI 10.1111/j.1365-2141.2006.06403.x
    • van der Holt B, Breems DA, Berna Beverloo H, et al. Various distinctive cytogenetic abnormalities in patients with acute myeloid leukaemia aged 60 years and older express adverse prognostic value: results from a prospective clinical trial. Br J Haematol. 2007;136(1):96-105. (Pubitemid 44912593)
    • (2007) British Journal of Haematology , vol.136 , Issue.1 , pp. 96-105
    • Van Der Holt, B.1    Breems, D.A.2    Berna Beverloo, H.3    Van Den Berg, E.4    Burnett, A.K.5    Sonneveld, P.6    Lowenberg, B.7
  • 17
    • 34547602163 scopus 로고    scopus 로고
    • GeneTrail - Advanced gene set enrichment analysis
    • Backes C, Keller A, Kuentzer J, et al. GeneTrail - advanced gene set enrichment analysis. Nucleic Acids Res. 2007;35(Web Server issue):W186-W192.
    • (2007) Nucleic Acids Res , vol.35 , Issue.WEB SERVER ISSUE
    • Backes, C.1    Keller, A.2    Kuentzer, J.3
  • 18
    • 28544433482 scopus 로고    scopus 로고
    • Peritumoral lymphatic vessel density and vascular endothelial growth factor C expression in early-stage squamous cell carcinoma of the uterine cervix
    • Gombos Z, Xu X, Chu CS, et al. Peritumoral lymphatic vessel density and vascular endothelial growth factor C expression in early-stage squamous cell carcinoma of the uterine cervix. Clin Cancer Res. 2005;11(23):8364-8371.
    • (2005) Clin Cancer Res , vol.11 , Issue.23 , pp. 8364-8371
    • Gombos, Z.1    Xu, X.2    Chu, C.S.3
  • 19
    • 49249087039 scopus 로고    scopus 로고
    • Antitumor activity and biomarker analysis of sunitinib in patients with bevacizumab-refractory metastatic renal cell carcinoma
    • Rini BI, Michaelson MD, Rosenberg JE, et al. Antitumor activity and biomarker analysis of sunitinib in patients with bevacizumab-refractory metastatic renal cell carcinoma. J Clin Oncol. 2008;26(22):3743-3748.
    • (2008) J Clin Oncol , vol.26 , Issue.22 , pp. 3743-3748
    • Rini, B.I.1    Michaelson, M.D.2    Rosenberg, J.E.3
  • 20
    • 20944436359 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-C expression and invasive phenotype in ovarian carcinomas
    • Ueda M, Hung YC, Terai Y, et al. Vascular endothelial growth factor-C expression and invasive phenotype in ovarian carcinomas. Clin Cancer Res. 2005;11(9):3225-3232.
    • (2005) Clin Cancer Res , vol.11 , Issue.9 , pp. 3225-3232
    • Ueda, M.1    Hung, Y.C.2    Terai, Y.3
  • 21
    • 47149087181 scopus 로고    scopus 로고
    • Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia
    • Tomasson MH, Xiang Z, Walgren R, et al. Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia. Blood. 2008;111(9):4797-4808.
    • (2008) Blood , vol.111 , Issue.9 , pp. 4797-4808
    • Tomasson, M.H.1    Xiang, Z.2    Walgren, R.3
  • 22
    • 0032080604 scopus 로고    scopus 로고
    • Activation of p21-CDC42/Rac-activated kinases by CD28 signaling: P21- Activated kinase (PAK) and MEK kinase 1 (MEKK1) may mediate the interplay between CD3 and CD28 signals
    • Kaga S, Ragg S, Rogers KA, et al. Activation of p21-CDC42/Rac-activated kinases by CD28 signaling: p21-activated kinase (PAK) and MEK kinase 1 (MEKK1) may mediate the interplay between CD3 and CD28 signals. J Immunol. 1998;160(9):4182-4189. (Pubitemid 28217271)
    • (1998) Journal of Immunology , vol.160 , Issue.9 , pp. 4182-4189
    • Kaga, S.1    Ragg, S.2    Rogers, K.A.3    Ochi, A.4
  • 23
    • 2942675416 scopus 로고    scopus 로고
    • PAK is essential for RAS-induced upregulation of cyclin D1 during the G1 to S transition
    • Nheu T, He H, Hirokawa Y, et al. PAK is essential for RAS-induced upregulation of cyclin D1 during the G1 to S transition. Cell Cycle. 2004;3(1):71-74.
    • (2004) Cell Cycle , vol.3 , Issue.1 , pp. 71-74
    • Nheu, T.1    He, H.2    Hirokawa, Y.3
  • 24
    • 34249282040 scopus 로고    scopus 로고
    • MEK1 activation by PAK: A novel mechanism
    • Park ER, Eblen ST, Catling AD, et al. MEK1 activation by PAK: a novel mechanism. Cell Signal. 2007;19(7):1488-1496.
    • (2007) Cell Signal , vol.19 , Issue.7 , pp. 1488-1496
    • Park, E.R.1    Eblen, S.T.2    Catling, A.D.3
  • 25
    • 2442444247 scopus 로고    scopus 로고
    • Vav1 transduces T cell receptor signals to the activation of the Ras/ERK pathway via LAT, Sos, and RasGRP1
    • Reynolds LF, de Bettignies C, Norton T, et al. Vav1 transduces T cell receptor signals to the activation of the Ras/ERK pathway via LAT, Sos, and RasGRP1. J Biol Chem. 2004;279(18):18239-18246.
    • (2004) J Biol Chem , vol.279 , Issue.18 , pp. 18239-18246
    • Reynolds, L.F.1    De Bettignies, C.2    Norton, T.3
  • 27
    • 0036550053 scopus 로고    scopus 로고
    • 3′-phosphoinositide-dependent kinase-1 (PDK-1) in PI 3-kinase signaling
    • Storz P, Toker A. 3′-phosphoinositide-dependent kinase-1 (PDK-1) in PI 3-kinase signaling. Front Biosci. 2002;7:d886-d902.
    • (2002) Front Biosci , vol.7
    • Storz, P.1    Toker, A.2
  • 28
    • 0036527585 scopus 로고    scopus 로고
    • Molecular mechanisms of lymphangiogenesis in health and disease
    • Alitalo K, Carmeliet P. Molecular mechanisms of lymphangiogenesis in health and disease. Cancer Cell. 2002;1(3):219-227.
    • (2002) Cancer Cell , vol.1 , Issue.3 , pp. 219-227
    • Alitalo, K.1    Carmeliet, P.2
  • 30
    • 0030453355 scopus 로고    scopus 로고
    • VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development
    • Kukk E, Lymboussaki A, Taira S, et al. VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development. Development. 1996;122(12):3829-3837.
    • (1996) Development , vol.122 , Issue.12 , pp. 3829-3837
    • Kukk, E.1    Lymboussaki, A.2    Taira, S.3
  • 31
    • 0035122537 scopus 로고    scopus 로고
    • Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis
    • Skobe M, Hawighorst T, Jackson DG, et al. Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis. Nat Med. 2001;7(2):192-198.
    • (2001) Nat Med , vol.7 , Issue.2 , pp. 192-198
    • Skobe, M.1    Hawighorst, T.2    Jackson, D.G.3
  • 32
    • 0036144374 scopus 로고    scopus 로고
    • Lymphatic endothelium: A new frontier of metastasis research
    • DOI 10.1038/ncb0102-e2
    • Karkkainen MJ, Makinen T, Alitalo K. Lymphatic endothelium: a new frontier of metastasis research. Nat Cell Biol. 2002;4(1):E2-E5. (Pubitemid 34071967)
    • (2002) Nature Cell Biology , vol.4 , Issue.1
    • Karkkainen, M.J.1    Makinen, T.2    Alitalo, K.3
  • 33
    • 58149343910 scopus 로고    scopus 로고
    • Vascular endothelial growth factor C stimulates progression of human gastric cancer via both autocrine and paracrine mechanisms
    • Kodama M, Kitadai Y, Tanaka M, et al. Vascular endothelial growth factor C stimulates progression of human gastric cancer via both autocrine and paracrine mechanisms. Clin Cancer Res. 2008;14(22):7205-7214.
    • (2008) Clin Cancer Res , vol.14 , Issue.22 , pp. 7205-7214
    • Kodama, M.1    Kitadai, Y.2    Tanaka, M.3
  • 35
    • 0037401047 scopus 로고    scopus 로고
    • Malignant mesothelioma growth inhibition by agents that target the VEGF and VEGF-C autocrine loops
    • Masood R, Kundra A, Zhu S, et al. Malignant mesothelioma growth inhibition by agents that target the VEGF and VEGF-C autocrine loops. Int J Cancer. 2003;104(5):603-610.
    • (2003) Int J Cancer , vol.104 , Issue.5 , pp. 603-610
    • Masood, R.1    Kundra, A.2    Zhu, S.3
  • 36
    • 68049131465 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-C protects prostate cancer cells from oxidative stress by the activation of mammalian target of rapamycin complex-2 and AKT-1
    • Muders MH, Zhang H, Wang E, et al. Vascular endothelial growth factor-C protects prostate cancer cells from oxidative stress by the activation of mammalian target of rapamycin complex-2 and AKT-1. Cancer Res. 2009;69(15):6042-6048.
    • (2009) Cancer Res , vol.69 , Issue.15 , pp. 6042-6048
    • Muders, M.H.1    Zhang, H.2    Wang, E.3
  • 37
    • 34848908049 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-C and its receptor VEGFR-3 in non-small-cell lung cancer: Concurrent expression in cancer cells from primary tumour and metastatic lymph node
    • Saintigny P, Kambouchner M, Ly M, et al. Vascular endothelial growth factor-C and its receptor VEGFR-3 in non-small-cell lung cancer: concurrent expression in cancer cells from primary tumour and metastatic lymph node. Lung Cancer. 2007;58(2):205-213.
    • (2007) Lung Cancer , vol.58 , Issue.2 , pp. 205-213
    • Saintigny, P.1    Kambouchner, M.2    Ly, M.3
  • 38
    • 33847198622 scopus 로고    scopus 로고
    • The role of the VEGF-C/VEGFR-3 axis in cancer progression
    • Su JL, Yen CJ, Chen PS, et al. The role of the VEGF-C/VEGFR-3 axis in cancer progression. Br J Cancer. 2007;96(4):541-545.
    • (2007) Br J Cancer , vol.96 , Issue.4 , pp. 541-545
    • Su, J.L.1    Yen, C.J.2    Chen, P.S.3
  • 39
    • 35348910755 scopus 로고    scopus 로고
    • Migration-promoting role of VEGF-C and VEGF-C binding receptors in human breast cancer cells
    • DOI 10.1038/sj.bjc.6603993, PII 6603993
    • Timoshenko AV, Rastogi S, Lala PK. Migration-promoting role of VEGF-C and VEGF-C binding receptors in human breast cancer cells. Br J Cancer. 2007;97(8):1090-1098. (Pubitemid 47587011)
    • (2007) British Journal of Cancer , vol.97 , Issue.8 , pp. 1090-1098
    • Timoshenko, A.V.1    Rastogi, S.2    Lala, P.K.3
  • 40
    • 12244311480 scopus 로고    scopus 로고
    • Stage-specific characterization of the vascular endothelial growth factor axis in prostate cancer: Expression of lymphangiogenic markers is associated with advanced-stage disease
    • Kaushal V, Mukunyadzi P, Dennis RA, et al. Stage-specific characterization of the vascular endothelial growth factor axis in prostate cancer: expression of lymphangiogenic markers is associated with advanced-stage disease. Clin Cancer Res. 2005;11(2 Pt 1):584-593.
    • (2005) Clin Cancer Res , vol.11 , Issue.2 PART 1 , pp. 584-593
    • Kaushal, V.1    Mukunyadzi, P.2    Dennis, R.A.3
  • 41
    • 0037936730 scopus 로고    scopus 로고
    • Vascular endothelial growth factor C and vascular endothelial growth factor receptor 3 expression in squamous cell carcinomas of the head and neck
    • Neuchrist C, Erovic BM, Handisurya A, et al. Vascular endothelial growth factor C and vascular endothelial growth factor receptor 3 expression in squamous cell carcinomas of the head and neck. Head Neck. 2003;25(6):464-474.
    • (2003) Head Neck , vol.25 , Issue.6 , pp. 464-474
    • Neuchrist, C.1    Erovic, B.M.2    Handisurya, A.3
  • 42
    • 77953342817 scopus 로고    scopus 로고
    • HER2/neu expression correlates with vascular endothelial growth factor-C and lymphangiogenesis in lymph node-positive breast cancer
    • Schoppmann SF, Tamandl D, Roberts L, et al. HER2/neu expression correlates with vascular endothelial growth factor-C and lymphangiogenesis in lymph node-positive breast cancer. Ann Oncol. 2010;21(5):955-960.
    • (2010) Ann Oncol , vol.21 , Issue.5 , pp. 955-960
    • Schoppmann, S.F.1    Tamandl, D.2    Roberts, L.3
  • 43
    • 33644822574 scopus 로고    scopus 로고
    • The VEGF-C/Flt-4 axis promotes invasion and metastasis of cancer cells
    • Su JL, Yang PC, Shih JY, et al. The VEGF-C/Flt-4 axis promotes invasion and metastasis of cancer cells. Cancer Cell. 2006;9(3):209-223.
    • (2006) Cancer Cell , vol.9 , Issue.3 , pp. 209-223
    • Su, J.L.1    Yang, P.C.2    Shih, J.Y.3
  • 44
    • 40749117992 scopus 로고    scopus 로고
    • Expression of VEGF-C and its receptor VEGFR-3 in the bone marrow of patients with acute myeloid leukaemia
    • DOI 10.1016/j.leukres.2007.10.005, PII S0145212607003992
    • Liersch R, Schliemann C, Bieker R, et al. Expression of VEGF-C and its receptor VEGFR-3 in the bone marrow of patients with acute myeloid leukaemia. Leuk Res. 2008;32(6):954-961. (Pubitemid 351389550)
    • (2008) Leukemia Research , vol.32 , Issue.6 , pp. 954-961
    • Liersch, R.1    Schliemann, C.2    Bieker, R.3    Hintelmann, H.4    Buechner, T.5    Berdel, W.E.6    Mesters, R.M.7
  • 45
    • 0033861874 scopus 로고    scopus 로고
    • Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration
    • Dias S, Hattori K, Zhu Z, et al. Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration. J Clin Invest. 2000;106(4):511-521.
    • (2000) J Clin Invest , vol.106 , Issue.4 , pp. 511-521
    • Dias, S.1    Hattori, K.2    Zhu, Z.3
  • 46
    • 0035845561 scopus 로고    scopus 로고
    • Inhibition of both paracrine and autocrine VEGF/VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemias
    • Dias S, Hattori K, Heissig B, et al. Inhibition of both paracrine and autocrine VEGF/VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemias. Proc Natl Acad Sci U S A. 2001;98(19):10857-10862.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.19 , pp. 10857-10862
    • Dias, S.1    Hattori, K.2    Heissig, B.3
  • 47
    • 20044371963 scopus 로고    scopus 로고
    • Analysis of concerted expression of angiogenic growth factors in acute myeloid leukemia: Expression of angiopoietin-2 represents an independent prognostic factor for overall survival
    • Loges S, Heil G, Bruweleit M, et al. Analysis of concerted expression of angiogenic growth factors in acute myeloid leukemia: expression of angiopoietin-2 represents an independent prognostic factor for overall survival. J Clin Oncol. 2005;23(6):1109-1117.
    • (2005) J Clin Oncol , vol.23 , Issue.6 , pp. 1109-1117
    • Loges, S.1    Heil, G.2    Bruweleit, M.3
  • 49
    • 34249679271 scopus 로고    scopus 로고
    • ABC transporters and drug resistance in leukemia: Was P-gp nothing but the first head of the Hydra?
    • DOI 10.1038/sj.leu.2404692, PII 2404692
    • Steinbach D, Legrand O. ABC transporters and drug resistance in leukemia: was P-gp nothing but the first head of the Hydra? Leukemia. 2007;21(6):1172-1176. (Pubitemid 46831804)
    • (2007) Leukemia , vol.21 , Issue.6 , pp. 1172-1176
    • Steinbach, D.1    Legrand, O.2
  • 50
    • 29344440700 scopus 로고    scopus 로고
    • Expression of multidrug resistance-associated proteins predicts prognosis in childhood and adult acute lymphoblastic leukemia
    • Plasschaert SL, de Bont ES, Boezen M, et al. Expression of multidrug resistance-associated proteins predicts prognosis in childhood and adult acute lymphoblastic leukemia. Clin Cancer Res. 2005;11(24 Pt 1):8661-8668.
    • (2005) Clin Cancer Res , vol.11 , Issue.24 PART 1 , pp. 8661-8668
    • Plasschaert, S.L.1    De Bont, E.S.2    Boezen, M.3
  • 51
    • 0345167873 scopus 로고    scopus 로고
    • The multi-drug resistance-associated protein 3 (MRP3) is associated with a poor outcome in childhood ALL and may account for the worse prognosis in male patients and T-cell immunophenotype
    • Steinbach D, Wittig S, Cario G, et al. The multi-drug resistance-associated protein 3 (MRP3) is associated with a poor outcome in childhood ALL and may account for the worse prognosis in male patients and T-cell immunophenotype. Blood. 2003;102(13):4493-4498.
    • (2003) Blood , vol.102 , Issue.13 , pp. 4493-4498
    • Steinbach, D.1    Wittig, S.2    Cario, G.3
  • 52
    • 13044294031 scopus 로고    scopus 로고
    • MRP3, an organic anion transporter able to transport anti-cancer drugs
    • Kool M, van der Linden M, de Haas M, et al. MRP3, an organic anion transporter able to transport anti-cancer drugs. Proc Natl Acad Sci U S A. 1999;96(12):6914-6919.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , Issue.12 , pp. 6914-6919
    • Kool, M.1    Van Der Linden, M.2    De Haas, M.3
  • 53
    • 0035824674 scopus 로고    scopus 로고
    • Characterization of Drug Transport by the Human Multidrug Resistance Protein 3 (ABCC3)
    • DOI 10.1074/jbc.M107041200
    • Zelcer N, Saeki T, Reid G, et al. Characterization of drug transport by the human multidrug resistance protein 3 (ABCC3). J Biol Chem. 2001;276(49):46400-46407. (Pubitemid 33646920)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.49 , pp. 46400-46407
    • Zelcer, N.1    Saeki, T.2    Reid, G.3    Beijnen, J.H.4    Borst, P.5


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