-
1
-
-
0035925098
-
Tumor hypoxia: Definitions and current clinical, biologic, and molecular aspects
-
Höckel M, Vaupel P. Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects. J Natl Cancer Inst 2001;93:266-76.
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 266-276
-
-
Höckel, M.1
Vaupel, P.2
-
2
-
-
0034037286
-
Microenvironment-induced cancer metastasis
-
Rofstad EK. Microenvironment-induced cancer metastasis. Int J Radiat Biol 2000;76:589-605.
-
(2000)
Int J Radiat Biol
, vol.76
, pp. 589-605
-
-
Rofstad, E.K.1
-
3
-
-
34547121206
-
Hypoxia in cancer: Significance and impact on clinical outcome
-
DOI 10.1007/s10555-007-9055-1, Special issue on Hypoxia and Cancer, Guest Editor: Gregg L. Semenza
-
Vaupel P, Mayer A. Hypoxia in cancer: significance and impact on clinical outcome. Cancer Metastasis Rev 2007;26:225-39. (Pubitemid 47101660)
-
(2007)
Cancer and Metastasis Reviews
, vol.26
, Issue.2
, pp. 225-239
-
-
Vaupel, P.1
Mayer, A.2
-
5
-
-
0032053823
-
The unique physiology of solid tumors: Opportunities (and problems) for cancer therapy
-
Brown JM, Giaccia AJ. The unique physiology of solid tumors: opportunities (and problems) for cancer therapy. Cancer Res 1998;58:1408-16.
-
(1998)
Cancer Res
, vol.58
, pp. 1408-1416
-
-
Brown, J.M.1
Giaccia, A.J.2
-
6
-
-
0029994483
-
Tumor oxygenation: A matter of supply and demand
-
Gulledge CJ, Dewhirst MW. Tumor oxygenation: a matter of supply and demand. Anticancer Res 1996;16:741-9.
-
(1996)
Anticancer Res
, vol.16
, pp. 741-749
-
-
Gulledge, C.J.1
Dewhirst, M.W.2
-
8
-
-
44349157832
-
Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response
-
Dewhirst MW, Cao Y, Möller B. Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response. Nat Rev Cancer 2008;8:425-37.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 425-437
-
-
Dewhirst, M.W.1
Cao, Y.2
Möller, B.3
-
10
-
-
0031878655
-
Concepts of oxygen transport at the microcirculatory level
-
Dewhirst MW. Concepts of oxygen transport at the microcirculatory level. Semin Radiat Oncol 1998;8:143-50.
-
(1998)
Semin Radiat Oncol
, vol.8
, pp. 143-150
-
-
Dewhirst, M.W.1
-
11
-
-
0029123236
-
Nicotinamide and other benzamide analogs as agents for overcoming hypoxic cell radiation resistance in tumours
-
Horsman MR. Nicotinamide and other benzamide analogs as agents for overcoming hypoxic cell radiation resistance in tumours. Acta Oncol 1995;34:571-87.
-
(1995)
Acta Oncol
, vol.34
, pp. 571-587
-
-
Horsman, M.R.1
-
14
-
-
0010170555
-
Hypoxia induces DNA overreplication and enhances metastatic potential of murine tumor cells
-
Young SD, Marshall RS, Hill RP. Hypoxia induces DNA overreplication and enhances metastatic potential of murine tumor cells. Proc Natl Acad Sci USA 1988;85:9533-7.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 9533-9537
-
-
Young, S.D.1
Marshall, R.S.2
Hill, R.P.3
-
15
-
-
0032774194
-
Hypoxia-induced metastasis of human melanoma cells: Involvement of vascular endothelial growth factor-mediated angiogenesis
-
Rofstad EK, Danielsen T. Hypoxia-induced metastasis of human melanoma cells: involvement of vascular endothelial growth factor-mediated angiogenesis. Br J Cancer 1999;80:1697-707.
-
(1999)
Br J Cancer
, vol.80
, pp. 1697-1707
-
-
Rofstad, E.K.1
Danielsen, T.2
-
17
-
-
0035893396
-
Acute (cyclic) hypoxia enhances spontaneous metastasis of KHT murine tumors
-
Cairns RA, Kalliomäki T, Hill RP. Acute (cyclic) hypoxia enhances spontaneous metastasis of KHT murine tumors. Cancer Res 2001;61:8903-8.
-
(2001)
Cancer Res
, vol.61
, pp. 8903-8908
-
-
Cairns, R.A.1
Kalliomäki, T.2
Hill, R.P.3
-
18
-
-
1542405875
-
Acute hypoxia enhances spontaneous lymph node metastasis in an orthotopic murine model of human cervical carcinoma
-
Cairns RA, Hill RP. Acute hypoxia enhances spontaneous lymph node metastasis in an orthotopic murine model of human cervical carcinoma. Cancer Res 2004;64:2054-61.
-
(2004)
Cancer Res
, vol.64
, pp. 2054-2061
-
-
Cairns, R.A.1
Hill, R.P.2
-
19
-
-
45449100940
-
Analysis of the effects of exposure to acute hypoxia on oxidative lesions and tumour progression in a transgenic mouse breast cancer model
-
Kalliomäki TM, McCallum G, Lunt SJ, Wells PG, Hill RP. Analysis of the effects of exposure to acute hypoxia on oxidative lesions and tumour progression in a transgenic mouse breast cancer model. BMC Cancer 2008;8:151.
-
(2008)
BMC Cancer
, vol.8
, pp. 151
-
-
Kalliomäki, T.M.1
McCallum, G.2
Lunt, S.J.3
Wells, P.G.4
Hill, R.P.5
-
20
-
-
67649413123
-
Progression and metastasis in a transgenic mouse breast cancer model: Effects of exposure to in vivo hypoxia
-
Kalliomäki TM, McCallum G, Wells PG, Hill RP. Progression and metastasis in a transgenic mouse breast cancer model: effects of exposure to in vivo hypoxia. Cancer Lett 2009;282:98-108.
-
(2009)
Cancer Lett
, vol.282
, pp. 98-108
-
-
Kalliomäki, T.M.1
McCallum, G.2
Wells, P.G.3
Hill, R.P.4
-
21
-
-
18244390016
-
Hypoxia-associated spontaneous pulmonary metastasis in human melanoma xenografts: Involvement of microvascular hot spots induced in hypoxic foci by interleukin 8
-
Rofstad EK, Halsør EF. Hypoxia-associated spontaneous pulmonary metastasis in human melanoma xenografts: involvement of microvascular hot spots induced in hypoxic foci by interleukin 8. Br J Cancer 2002;86:301-8.
-
(2002)
Br J Cancer
, vol.86
, pp. 301-308
-
-
Rofstad, E.K.1
Halsør, E.F.2
-
22
-
-
0037086083
-
Hypoxia promotes lymph node metastasis in human melanoma xenografts by up-regulating the urokinase-type plasminogen activator receptor
-
Rofstad EK, Rasmussen H, Galappathi K, Mathiesen B, Nilsen K, Graff BA. Hypoxia promotes lymph node metastasis in human melanoma xenografts by up-regulating the urokinase-type plasminogen activator receptor. Cancer Res 2002;62:1847-53.
-
(2002)
Cancer Res
, vol.62
, pp. 1847-1853
-
-
Rofstad, E.K.1
Rasmussen, H.2
Galappathi, K.3
Mathiesen, B.4
Nilsen, K.5
Graff, B.A.6
-
23
-
-
0036468521
-
Pulmonary and lymph node metastasis is associated with primary tumor interstitial fluid pressure in human melanoma xenografts
-
Rofstad EK, Tunheim SH, Mathiesen B, Graff BA, Halsør EF, Nilsen K, Galappathi K. Pulmonary and lymph node metastasis is associated with primary tumor interstitial fluid pressure in human melanoma xenografts. Cancer Res 2002;62:661-4.
-
(2002)
Cancer Res
, vol.62
, pp. 661-664
-
-
Rofstad, E.K.1
Tunheim, S.H.2
Mathiesen, B.3
Graff, B.A.4
Halsør, E.F.5
Nilsen, K.6
Galappathi, K.7
-
24
-
-
0028005442
-
Orthotopic human melanoma xenograft model systems for studies of tumour angiogenesis, pathophysiology, treatment sensitivity and metastatic pattern
-
Rofstad EK. Orthotopic human melanoma xenograft model systems for studies of tumour angiogenesis, pathophysiology, treatment sensitivity and metastatic pattern. Br J Cancer 1994;70:804-12.
-
(1994)
Br J Cancer
, vol.70
, pp. 804-812
-
-
Rofstad, E.K.1
-
25
-
-
62549127298
-
Dynamic contrast-enhanced magnetic resonance imaging of tumor interstitial fluid pressure
-
Gulliksrud K, Brurberg KG, Rofstad EK. Dynamic contrast-enhanced magnetic resonance imaging of tumor interstitial fluid pressure. Radiother Oncol 2009;91:107-13.
-
(2009)
Radiother Oncol
, vol.91
, pp. 107-113
-
-
Gulliksrud, K.1
Brurberg, K.G.2
Rofstad, E.K.3
-
26
-
-
35148824761
-
Assessment of microvascular density, extracellular volume fraction, and radiobiological hypoxia in human melanoma xenografts by dynamic contrast-enhanced MRI
-
Vestvik IK, Egeland TA, Gaustad JV, Mathiesen B, Rofstad EK. Assessment of microvascular density, extracellular volume fraction, and radiobiological hypoxia in human melanoma xenografts by dynamic contrast-enhanced MRI. J Magn Reson Imaging 2007;26:1033-42.
-
(2007)
J Magn Reson Imaging
, vol.26
, pp. 1033-1042
-
-
Vestvik, I.K.1
Egeland, T.A.2
Gaustad, J.V.3
Mathiesen, B.4
Rofstad, E.K.5
-
27
-
-
0028356794
-
Method for the quantitative assessment of contrast agent uptake in dynamic contrast-enhanced MRI
-
Hittmair K, Gomiscek G, Langenberger K, Recht M, Imhof H, Kramer J. Method for the quantitative assessment of contrast agent uptake in dynamic contrast-enhanced MRI. Magn Reson Med 1994;31:567-71. (Pubitemid 24129954)
-
(1994)
Magnetic Resonance in Medicine
, vol.31
, Issue.5
, pp. 567-571
-
-
Hittmair, K.1
Gomiscek, G.2
Langenberger, K.3
Recht, M.4
Imhof, H.5
Kramer, J.6
-
28
-
-
3543119624
-
Assessment of tumor blood perfusion by high-resolution dynamic contrast-enhanced MRI: A preclinical study of human melanoma xenografts
-
Benjaminsen IC, Graff BA, Brurberg KG, Rofstad EK. Assessment of tumor blood perfusion by high-resolution dynamic contrast-enhanced MRI: a preclinical study of human melanoma xenografts. Magn Reson Med 2004;52:269-76.
-
(2004)
Magn Reson Med
, vol.52
, pp. 269-276
-
-
Benjaminsen, I.C.1
Graff, B.A.2
Brurberg, K.G.3
Rofstad, E.K.4
-
29
-
-
0032828135
-
Estimating kinetic parameters from dynamic contrast-enhanced T1-weighted MRI of a diffusable tracer: Standardized quantities and symbols
-
Tofts PS, Brix G, Buckley DL, Evelhoch JL, Henderson E, Knopp MV, Larsson HBW, Lee TY, Mayr NA, Parker GJM, Port RE, Taylor J et al. Estimating kinetic parameters from dynamic contrast-enhanced T1-weighted MRI of a diffusable tracer: standardized quantities and symbols. J Magn Reson Imaging 1999;10:223-32.
-
(1999)
J Magn Reson Imaging
, vol.10
, pp. 223-232
-
-
Tofts, P.S.1
Brix, G.2
Buckley, D.L.3
Evelhoch, J.L.4
Henderson, E.5
Knopp, M.V.6
Larsson, H.B.W.7
Lee, T.Y.8
Mayr, N.A.9
Parker, G.J.M.10
Port, R.E.11
Taylor, J.12
-
30
-
-
70349911870
-
Dynamic contrast-enhanced magnetic resonance imaging of tumors: Preclinical validation of parametric images
-
Egeland TA, Simonsen TG, Gaustad JV, Gulliksrud K, Ellingsen C, Rofstad EK. Dynamic contrast-enhanced magnetic resonance imaging of tumors: preclinical validation of parametric images. Radiat Res 2009;172:339-47.
-
(2009)
Radiat Res
, vol.172
, pp. 339-347
-
-
Egeland, T.A.1
Simonsen, T.G.2
Gaustad, J.V.3
Gulliksrud, K.4
Ellingsen, C.5
Rofstad, E.K.6
-
31
-
-
0032698303
-
Radiobiological and immunohistochemical assessment of hypoxia in human melanoma xenografts: Acute and chronic hypoxia in individual tumours
-
Rofstad EK, Måseide K. Radiobiological and immunohistochemical assessment of hypoxia in human melanoma xenografts: acute and chronic hypoxia in individual tumours. Int J Radiat Biol 1999;75:1377-93.
-
(1999)
Int J Radiat Biol
, vol.75
, pp. 1377-1393
-
-
Rofstad, E.K.1
Måseide, K.2
-
32
-
-
0042575345
-
Temporal heterogeneity in oxygen tension in human melanoma xenografts
-
Brurberg KG, Graff BA, Rofstad EK. Temporal heterogeneity in oxygen tension in human melanoma xenografts. Br J Cancer 2003;89:350-6.
-
(2003)
Br J Cancer
, vol.89
, pp. 350-356
-
-
Brurberg, K.G.1
Graff, B.A.2
Rofstad, E.K.3
-
33
-
-
77951222660
-
Simulation-based comparison of two approaches frequently used for dynamic contrast-enhanced MRI
-
Zwick S, Brix G, Tofts PS, Strecker R, Kopp-Schneider A, Laue H, Semmler W, Kiessling F. Simulation-based comparison of two approaches frequently used for dynamic contrast-enhanced MRI. Eur Radiol 2010;20:432-42.
-
(2010)
Eur Radiol
, vol.20
, pp. 432-442
-
-
Zwick, S.1
Brix, G.2
Tofts, P.S.3
Strecker, R.4
Kopp-Schneider, A.5
Laue, H.6
Semmler, W.7
Kiessling, F.8
-
34
-
-
0028114985
-
The implications of angiogenesis for the biology and therapy of cancer metastasis
-
Fidler IJ, Ellis LM. The implications of angiogenesis for the biology and therapy of cancer metastasis. Cell 1994;79:185-8.
-
(1994)
Cell
, vol.79
, pp. 185-188
-
-
Fidler, I.J.1
Ellis, L.M.2
-
35
-
-
0034283023
-
Vascular endothelial growth factor, interleukin-8, platelet-derived endothelial cell growth factor, and basic fibroblast growth factor promote angiogenesis and metastasis in human melanoma xenografts
-
Rofstad EK, Halsør EF. Vascular endothelial growth factor, interleukin-8, platelet-derived endothelial cell growth factor, and basic fibroblast growth factor promote angiogenesis and metastasis in human melanoma xenografts. Cancer Res 2000;60:4932-8.
-
(2000)
Cancer Res
, vol.60
, pp. 4932-4938
-
-
Rofstad, E.K.1
Halsør, E.F.2
-
36
-
-
3042616216
-
Hypoxia enhances metastatic efficiency by up-regulating Mdm2 in KHT cells and increasing resistance to apoptosis
-
Zhang L, Hill RP. Hypoxia enhances metastatic efficiency by up-regulating Mdm2 in KHT cells and increasing resistance to apoptosis. Cancer Res 2004;64:4180-9.
-
(2004)
Cancer Res
, vol.64
, pp. 4180-4189
-
-
Zhang, L.1
Hill, R.P.2
-
37
-
-
65649136924
-
Increased expression of metastasis-related genes in hypoxic cells sorted from cervical and lymph nodal xenograft tumors
-
Chaudary N, Hill RP. Increased expression of metastasis-related genes in hypoxic cells sorted from cervical and lymph nodal xenograft tumors. Lab Invest 2009;89:587-96.
-
(2009)
Lab Invest
, vol.89
, pp. 587-596
-
-
Chaudary, N.1
Hill, R.P.2
|