Thrombin down-regulates the TGF-β-mediated synthesis of collagen and fibronectin by human proximal tubule epithelial cells through the EPCR-dependent activation of PAR-1

Journal of Cellular Physiology

Volumn 225, Issue 1, 2010, Pages 233-239

  Bae, Jong Sup ^a   Kim, In San ^b   Rezaie, Alireza R ^c  

^a Daegu Haany University   (South Korea)

^b Kyungpook National University School of Medicine   (South Korea)

^c SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; ENDOTHELIAL PROTEIN C RECEPTOR; FIBRONECTIN; INTERLEUKIN 6; INTERLEUKIN 8; PROTEIN C; PROTEINASE ACTIVATED RECEPTOR 1; SCLEROPROTEIN; THROMBIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR;

ARTICLE; CELL ACTIVATION; CELL LINE; COLLAGEN SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANTIGENS, CD; CELLS, CULTURED; COLLAGEN TYPE IV; EPITHELIAL CELLS; EXTRACELLULAR MATRIX PROTEINS; FIBRONECTINS; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; KIDNEY TUBULES, PROXIMAL; PROTEIN C; RECEPTOR, PAR-1; RECEPTORS, CELL SURFACE; THROMBIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 77956506654     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.22249     Document Type: Article

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