-
1
-
-
30744449235
-
Angiogenesis as a therapeutic target
-
10.1038/nature04483, 16355214
-
Ferrara N, Kerbel RS. Angiogenesis as a therapeutic target. Nature 2005, 438(7070):967-974. 10.1038/nature04483, 16355214.
-
(2005)
Nature
, vol.438
, Issue.7070
, pp. 967-974
-
-
Ferrara, N.1
Kerbel, R.S.2
-
2
-
-
34248575149
-
Integrating signals from RTKs to ERK/MAPK
-
10.1038/sj.onc.1210394, 17496910
-
McKay MM, Morrison DK. Integrating signals from RTKs to ERK/MAPK. Oncogene 2007, 26(22):3113-3121. 10.1038/sj.onc.1210394, 17496910.
-
(2007)
Oncogene
, vol.26
, Issue.22
, pp. 3113-3121
-
-
McKay, M.M.1
Morrison, D.K.2
-
3
-
-
0032559228
-
Sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways
-
10.1016/S0092-8674(00)80919-8, 9458049
-
Hacohen N, Kramer S, Sutherland D, Hiromi Y, Krasnow MA. sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways. Cell 1998, 92(2):253-263. 10.1016/S0092-8674(00)80919-8, 9458049.
-
(1998)
Cell
, vol.92
, Issue.2
, pp. 253-263
-
-
Hacohen, N.1
Kramer, S.2
Sutherland, D.3
Hiromi, Y.4
Krasnow, M.A.5
-
4
-
-
0032719944
-
Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed
-
Minowada G, Jarvis LA, Chi CL, Neubuser A, Sun X, Hacohen N, Krasnow MA, Martin GR. Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed. Development 1999, 126(20):4465-4475.
-
(1999)
Development
, vol.126
, Issue.20
, pp. 4465-4475
-
-
Minowada, G.1
Jarvis, L.A.2
Chi, C.L.3
Neubuser, A.4
Sun, X.5
Hacohen, N.6
Krasnow, M.A.7
Martin, G.R.8
-
5
-
-
30444441147
-
Sprouty proteins: multifaceted negative-feedback regulators of receptor tyrosine kinase signaling
-
10.1016/j.tcb.2005.11.004, 16337795
-
Mason JM, Morrison DJ, Basson MA, Licht JD. Sprouty proteins: multifaceted negative-feedback regulators of receptor tyrosine kinase signaling. Trends Cell Biol 2006, 16(1):45-54. 10.1016/j.tcb.2005.11.004, 16337795.
-
(2006)
Trends Cell Biol
, vol.16
, Issue.1
, pp. 45-54
-
-
Mason, J.M.1
Morrison, D.J.2
Basson, M.A.3
Licht, J.D.4
-
6
-
-
41049103244
-
Sprouty proteins, masterminds of receptor tyrosine kinase signaling
-
10.1007/s10456-008-9089-1, 18219583
-
Cabrita MA, Christofori G. Sprouty proteins, masterminds of receptor tyrosine kinase signaling. Angiogenesis 2008, 11(1):53-62. 10.1007/s10456-008-9089-1, 18219583.
-
(2008)
Angiogenesis
, vol.11
, Issue.1
, pp. 53-62
-
-
Cabrita, M.A.1
Christofori, G.2
-
7
-
-
70349310098
-
Intermolecular interactions of Sprouty proteins and their implications in development and disease
-
10.1124/mol.109.055848, 19570949
-
Edwin F, Anderson K, Ying C, Patel TB. Intermolecular interactions of Sprouty proteins and their implications in development and disease. Mol Pharmacol 2009, 76(4):679-691. 10.1124/mol.109.055848, 19570949.
-
(2009)
Mol Pharmacol
, vol.76
, Issue.4
, pp. 679-691
-
-
Edwin, F.1
Anderson, K.2
Ying, C.3
Patel, T.B.4
-
8
-
-
70149089678
-
Sprouty4 deficiency potentiates Ras-independent angiogenic signals and tumor growth
-
10.1111/j.1349-7006.2009.01214.x, 19493272
-
Taniguchi K, Ishizaki T, Ayada T, Sugiyama Y, Wakabayashi Y, Sekiya T, Nakagawa R, Yoshimura A. Sprouty4 deficiency potentiates Ras-independent angiogenic signals and tumor growth. Cancer Sci 2009, 100(9):1648-1654. 10.1111/j.1349-7006.2009.01214.x, 19493272.
-
(2009)
Cancer Sci
, vol.100
, Issue.9
, pp. 1648-1654
-
-
Taniguchi, K.1
Ishizaki, T.2
Ayada, T.3
Sugiyama, Y.4
Wakabayashi, Y.5
Sekiya, T.6
Nakagawa, R.7
Yoshimura, A.8
-
9
-
-
65549111249
-
Suppression of Sproutys has a therapeutic effect for a mouse model of ischemia by enhancing angiogenesis
-
10.1371/journal.pone.0005467, 2674940, 19424491
-
Taniguchi K, Sasaki K, Watari K, Yasukawa H, Imaizumi T, Ayada T, Okamoto F, Ishizaki T, Kato R, Kohno R, et al. Suppression of Sproutys has a therapeutic effect for a mouse model of ischemia by enhancing angiogenesis. PLoS One 2009, 4(5):e5467. 10.1371/journal.pone.0005467, 2674940, 19424491.
-
(2009)
PLoS One
, vol.4
, Issue.5
-
-
Taniguchi, K.1
Sasaki, K.2
Watari, K.3
Yasukawa, H.4
Imaizumi, T.5
Ayada, T.6
Okamoto, F.7
Ishizaki, T.8
Kato, R.9
Kohno, R.10
-
10
-
-
0033573994
-
Opposing actions of intact and N-terminal fragments of the human prolactin/growth hormone family members on angiogenesis: an efficient mechanism for the regulation of angiogenesis
-
10.1073/pnas.96.4.1246, 15448, 9990009
-
Struman I, Bentzien F, Lee H, Mainfroid V, D'Angelo G, Goffin V, Weiner RI, Martial JA. Opposing actions of intact and N-terminal fragments of the human prolactin/growth hormone family members on angiogenesis: an efficient mechanism for the regulation of angiogenesis. Proc Natl Acad Sci USA 1999, 96(4):1246-1251. 10.1073/pnas.96.4.1246, 15448, 9990009.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.4
, pp. 1246-1251
-
-
Struman, I.1
Bentzien, F.2
Lee, H.3
Mainfroid, V.4
D'Angelo, G.5
Goffin, V.6
Weiner, R.I.7
Martial, J.A.8
-
11
-
-
33749267074
-
Prolactin/growth hormone-derived antiangiogenic peptides highlight a potential role of tilted peptides in angiogenesis
-
10.1073/pnas.0606638103, 1599962, 16973751
-
Nguyen NQ, Tabruyn SP, Lins L, Lion M, Cornet AM, Lair F, Rentier-Delrue F, Brasseur R, Martial JA, Struman I. Prolactin/growth hormone-derived antiangiogenic peptides highlight a potential role of tilted peptides in angiogenesis. Proc Natl Acad Sci USA 2006, 103(39):14319-14324. 10.1073/pnas.0606638103, 1599962, 16973751.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.39
, pp. 14319-14324
-
-
Nguyen, N.Q.1
Tabruyn, S.P.2
Lins, L.3
Lion, M.4
Cornet, A.M.5
Lair, F.6
Rentier-Delrue, F.7
Brasseur, R.8
Martial, J.A.9
Struman, I.10
-
12
-
-
0037439683
-
Antitumor activity of the 16-kDa prolactin fragment in prostate cancer
-
Kim J, Luo W, Chen DT, Earley K, Tunstead J, Yu-Lee LY, Lin SH. Antitumor activity of the 16-kDa prolactin fragment in prostate cancer. Cancer Res 2003, 63(2):386-393.
-
(2003)
Cancer Res
, vol.63
, Issue.2
, pp. 386-393
-
-
Kim, J.1
Luo, W.2
Chen, D.T.3
Earley, K.4
Tunstead, J.5
Yu-Lee, L.Y.6
Lin, S.H.7
-
13
-
-
0035476272
-
Expression of the antiangiogenic factor 16 K hPRL in human HCT116 colon cancer cells inhibits tumor growth in Rag1(-/-) mice
-
Bentzien F, Struman I, Martini JF, Martial J, Weiner R. Expression of the antiangiogenic factor 16 K hPRL in human HCT116 colon cancer cells inhibits tumor growth in Rag1(-/-) mice. Cancer Res 2001, 61(19):7356-7362.
-
(2001)
Cancer Res
, vol.61
, Issue.19
, pp. 7356-7362
-
-
Bentzien, F.1
Struman, I.2
Martini, J.F.3
Martial, J.4
Weiner, R.5
-
14
-
-
36348957268
-
Inhibition of tumor growth and metastasis establishment by adenovirus-mediated gene transfer delivery of the antiangiogenic factor 16 K hPRL
-
10.1038/sj.mt.6300294, 17726458
-
Nguyen NQ, Cornet A, Blacher S, Tabruyn SP, Foidart JM, Noel A, Martial JA, Struman I. Inhibition of tumor growth and metastasis establishment by adenovirus-mediated gene transfer delivery of the antiangiogenic factor 16 K hPRL. Mol Ther 2007, 15(12):2094-2100. 10.1038/sj.mt.6300294, 17726458.
-
(2007)
Mol Ther
, vol.15
, Issue.12
, pp. 2094-2100
-
-
Nguyen, N.Q.1
Cornet, A.2
Blacher, S.3
Tabruyn, S.P.4
Foidart, J.M.5
Noel, A.6
Martial, J.A.7
Struman, I.8
-
15
-
-
69549135266
-
Antiangiogenic liposomal gene therapy with 16 K human prolactin efficiently reduces tumor growth
-
10.1016/j.canlet.2009.04.030, 19473755
-
Kinet V, Nguyen NQ, Sabatel C, Blacher S, Noel A, Martial JA, Struman I. Antiangiogenic liposomal gene therapy with 16 K human prolactin efficiently reduces tumor growth. Cancer Lett 2009, 284(2):222-228. 10.1016/j.canlet.2009.04.030, 19473755.
-
(2009)
Cancer Lett
, vol.284
, Issue.2
, pp. 222-228
-
-
Kinet, V.1
Nguyen, N.Q.2
Sabatel, C.3
Blacher, S.4
Noel, A.5
Martial, J.A.6
Struman, I.7
-
16
-
-
3142615282
-
Molecular targeting of antiangiogenic factor 16 K hPRL inhibits oxygen-induced retinopathy in mice
-
10.1167/iovs.03-1001, 15223825
-
Pan H, Nguyen NQ, Yoshida H, Bentzien F, Shaw LC, Rentier-Delrue F, Martial JA, Weiner R, Struman I, Grant MB. Molecular targeting of antiangiogenic factor 16 K hPRL inhibits oxygen-induced retinopathy in mice. Invest Ophthalmol Vis Sci 2004, 45(7):2413-2419. 10.1167/iovs.03-1001, 15223825.
-
(2004)
Invest Ophthalmol Vis Sci
, vol.45
, Issue.7
, pp. 2413-2419
-
-
Pan, H.1
Nguyen, N.Q.2
Yoshida, H.3
Bentzien, F.4
Shaw, L.C.5
Rentier-Delrue, F.6
Martial, J.A.7
Weiner, R.8
Struman, I.9
Grant, M.B.10
-
17
-
-
33846815521
-
A cathepsin D-cleaved 16 kDa form of prolactin mediates postpartum cardiomyopathy
-
10.1016/j.cell.2006.12.036, 17289576
-
Hilfiker-Kleiner D, Kaminski K, Podewski E, Bonda T, Schaefer A, Sliwa K, Forster O, Quint A, Landmesser U, Doerries C, et al. A cathepsin D-cleaved 16 kDa form of prolactin mediates postpartum cardiomyopathy. Cell 2007, 128(3):589-600. 10.1016/j.cell.2006.12.036, 17289576.
-
(2007)
Cell
, vol.128
, Issue.3
, pp. 589-600
-
-
Hilfiker-Kleiner, D.1
Kaminski, K.2
Podewski, E.3
Bonda, T.4
Schaefer, A.5
Sliwa, K.6
Forster, O.7
Quint, A.8
Landmesser, U.9
Doerries, C.10
-
18
-
-
0026566153
-
A specific, high affinity, saturable binding site for the 16-kilodalton fragment of prolactin on capillary endothelial cells
-
10.1210/en.130.3.1380, 1311239
-
Clapp C, Weiner RI. A specific, high affinity, saturable binding site for the 16-kilodalton fragment of prolactin on capillary endothelial cells. Endocrinology 1992, 130(3):1380-1386. 10.1210/en.130.3.1380, 1311239.
-
(1992)
Endocrinology
, vol.130
, Issue.3
, pp. 1380-1386
-
-
Clapp, C.1
Weiner, R.I.2
-
19
-
-
0033768751
-
The antiangiogenic factor 16 K PRL induces programmed cell death in endothelial cells by caspase activation
-
10.1210/me.14.10.1536, 11043570
-
Martini JF, Piot C, Humeau LM, Struman I, Martial JA, Weiner RI. The antiangiogenic factor 16 K PRL induces programmed cell death in endothelial cells by caspase activation. Mol Endocrinol 2000, 14(10):1536-1549. 10.1210/me.14.10.1536, 11043570.
-
(2000)
Mol Endocrinol
, vol.14
, Issue.10
, pp. 1536-1549
-
-
Martini, J.F.1
Piot, C.2
Humeau, L.M.3
Struman, I.4
Martial, J.A.5
Weiner, R.I.6
-
20
-
-
0042835765
-
The antiangiogenic factor 16 K human prolactin induces caspase-dependent apoptosis by a mechanism that requires activation of nuclear factor-kappaB
-
10.1210/me.2003-0132, 12791771
-
Tabruyn SP, Sorlet CM, Rentier-Delrue F, Bours V, Weiner RI, Martial JA, Struman I. The antiangiogenic factor 16 K human prolactin induces caspase-dependent apoptosis by a mechanism that requires activation of nuclear factor-kappaB. Mol Endocrinol 2003, 17(9):1815-1823. 10.1210/me.2003-0132, 12791771.
-
(2003)
Mol Endocrinol
, vol.17
, Issue.9
, pp. 1815-1823
-
-
Tabruyn, S.P.1
Sorlet, C.M.2
Rentier-Delrue, F.3
Bours, V.4
Weiner, R.I.5
Martial, J.A.6
Struman, I.7
-
21
-
-
22444446795
-
The antiangiogenic factor, 16-kDa human prolactin, induces endothelial cell cycle arrest by acting at both the G0-G1 and the G2-M phases
-
10.1210/me.2004-0515, 15746189
-
Tabruyn SP, Nguyen NQ, Cornet AM, Martial JA, Struman I. The antiangiogenic factor, 16-kDa human prolactin, induces endothelial cell cycle arrest by acting at both the G0-G1 and the G2-M phases. Mol Endocrinol 2005, 19(7):1932-1942. 10.1210/me.2004-0515, 15746189.
-
(2005)
Mol Endocrinol
, vol.19
, Issue.7
, pp. 1932-1942
-
-
Tabruyn, S.P.1
Nguyen, N.Q.2
Cornet, A.M.3
Martial, J.A.4
Struman, I.5
-
22
-
-
0033304596
-
16 K human prolactin inhibits vascular endothelial growth factor-induced activation of Ras in capillary endothelial cells
-
10.1210/me.13.5.692, 10319320
-
D'Angelo G, Martini JF, Iiri T, Fantl WJ, Martial J, Weiner RI. 16 K human prolactin inhibits vascular endothelial growth factor-induced activation of Ras in capillary endothelial cells. Mol Endocrinol 1999, 13(5):692-704. 10.1210/me.13.5.692, 10319320.
-
(1999)
Mol Endocrinol
, vol.13
, Issue.5
, pp. 692-704
-
-
D'Angelo, G.1
Martini, J.F.2
Iiri, T.3
Fantl, W.J.4
Martial, J.5
Weiner, R.I.6
-
23
-
-
34250904054
-
The angiostatic 16 K human prolactin overcomes endothelial cell anergy and promotes leukocyte infiltration via nuclear factor-kappaB activation
-
10.1210/me.2007-0021, 17405903
-
Tabruyn SP, Sabatel C, Nguyen NQ, Verhaeghe C, Castermans K, Malvaux L, Griffioen AW, Martial JA, Struman I. The angiostatic 16 K human prolactin overcomes endothelial cell anergy and promotes leukocyte infiltration via nuclear factor-kappaB activation. Mol Endocrinol 2007, 21(6):1422-1429. 10.1210/me.2007-0021, 17405903.
-
(2007)
Mol Endocrinol
, vol.21
, Issue.6
, pp. 1422-1429
-
-
Tabruyn, S.P.1
Sabatel, C.2
Nguyen, N.Q.3
Verhaeghe, C.4
Castermans, K.5
Malvaux, L.6
Griffioen, A.W.7
Martial, J.A.8
Struman, I.9
-
24
-
-
0035809919
-
Mammalian sprouty-1 and -2 are membrane-anchored phosphoprotein inhibitors of growth factor signaling in endothelial cells
-
10.1083/jcb.152.5.1087, 2198812, 11238463
-
Impagnatiello MA, Weitzer S, Gannon G, Compagni A, Cotten M, Christofori G. Mammalian sprouty-1 and -2 are membrane-anchored phosphoprotein inhibitors of growth factor signaling in endothelial cells. J Cell Biol 2001, 152(5):1087-1098. 10.1083/jcb.152.5.1087, 2198812, 11238463.
-
(2001)
J Cell Biol
, vol.152
, Issue.5
, pp. 1087-1098
-
-
Impagnatiello, M.A.1
Weitzer, S.2
Gannon, G.3
Compagni, A.4
Cotten, M.5
Christofori, G.6
-
25
-
-
4444261024
-
Angiogenesis gene expression profiling in xenograft models to study cellular interactions
-
10.1016/j.yexcr.2004.06.014, 15350528
-
Thijssen VL, Brandwijk RJ, Dings RP, Griffioen AW. Angiogenesis gene expression profiling in xenograft models to study cellular interactions. Exp Cell Res 2004, 299(2):286-293. 10.1016/j.yexcr.2004.06.014, 15350528.
-
(2004)
Exp Cell Res
, vol.299
, Issue.2
, pp. 286-293
-
-
Thijssen, V.L.1
Brandwijk, R.J.2
Dings, R.P.3
Griffioen, A.W.4
-
26
-
-
1842484160
-
Role of NF-kappa B in cell survival and transcription of latent membrane protein 1-expressing or Epstein-Barr virus latency III-infected cells
-
10.1128/JVI.78.8.4108-4119.2004, 374271, 15047827
-
Cahir-McFarland ED, Carter K, Rosenwald A, Giltnane JM, Henrickson SE, Staudt LM, Kieff E. Role of NF-kappa B in cell survival and transcription of latent membrane protein 1-expressing or Epstein-Barr virus latency III-infected cells. J Virol 2004, 78(8):4108-4119. 10.1128/JVI.78.8.4108-4119.2004, 374271, 15047827.
-
(2004)
J Virol
, vol.78
, Issue.8
, pp. 4108-4119
-
-
Cahir-McFarland, E.D.1
Carter, K.2
Rosenwald, A.3
Giltnane, J.M.4
Henrickson, S.E.5
Staudt, L.M.6
Kieff, E.7
-
27
-
-
0035824694
-
Mammalian sprouty proteins inhibit cell growth and differentiation by preventing ras activation
-
10.1074/jbc.M108234200, 11585837
-
Gross I, Bassit B, Benezra M, Licht JD. Mammalian sprouty proteins inhibit cell growth and differentiation by preventing ras activation. J Biol Chem 2001, 276(49):46460-46468. 10.1074/jbc.M108234200, 11585837.
-
(2001)
J Biol Chem
, vol.276
, Issue.49
, pp. 46460-46468
-
-
Gross, I.1
Bassit, B.2
Benezra, M.3
Licht, J.D.4
-
28
-
-
34248563290
-
The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition
-
10.1038/sj.onc.1210414, 17496918
-
Meloche S, Pouyssegur J. The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition. Oncogene 2007, 26(22):3227-3239. 10.1038/sj.onc.1210414, 17496918.
-
(2007)
Oncogene
, vol.26
, Issue.22
, pp. 3227-3239
-
-
Meloche, S.1
Pouyssegur, J.2
-
29
-
-
0038052805
-
The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer
-
10.1046/j.1365-2184.2003.00266.x, 12814430
-
Vermeulen K, Van Bockstaele DR, Berneman ZN. The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer. Cell Prolif 2003, 36(3):131-149. 10.1046/j.1365-2184.2003.00266.x, 12814430.
-
(2003)
Cell Prolif
, vol.36
, Issue.3
, pp. 131-149
-
-
Vermeulen, K.1
Van Bockstaele, D.R.2
Berneman, Z.N.3
-
30
-
-
5444225413
-
Cell cycle inhibitors in normal and tumor stem cells
-
10.1038/sj.onc.1207945, 15378085
-
Cheng T. Cell cycle inhibitors in normal and tumor stem cells. Oncogene 2004, 23(43):7256-7266. 10.1038/sj.onc.1207945, 15378085.
-
(2004)
Oncogene
, vol.23
, Issue.43
, pp. 7256-7266
-
-
Cheng, T.1
-
31
-
-
42749091148
-
Inhibition of the ERK phosphorylation plays a role in terbinafine-induced p21 up-regulation and DNA synthesis inhibition in human vascular endothelial cells
-
10.1016/j.taap.2007.12.028, 18272192
-
Ho PY, Hsu SP, Liang YC, Kuo ML, Ho YS, Lee WS. Inhibition of the ERK phosphorylation plays a role in terbinafine-induced p21 up-regulation and DNA synthesis inhibition in human vascular endothelial cells. Toxicol Appl Pharmacol 2008, 229(1):86-93. 10.1016/j.taap.2007.12.028, 18272192.
-
(2008)
Toxicol Appl Pharmacol
, vol.229
, Issue.1
, pp. 86-93
-
-
Ho, P.Y.1
Hsu, S.P.2
Liang, Y.C.3
Kuo, M.L.4
Ho, Y.S.5
Lee, W.S.6
-
32
-
-
0032498640
-
Integrin alphavbeta3 requirement for sustained mitogen-activated protein kinase activity during angiogenesis
-
10.1083/jcb.140.5.1255, 2132684, 9490736
-
Eliceiri BP, Klemke R, Stromblad S, Cheresh DA. Integrin alphavbeta3 requirement for sustained mitogen-activated protein kinase activity during angiogenesis. J Cell Biol 1998, 140(5):1255-1263. 10.1083/jcb.140.5.1255, 2132684, 9490736.
-
(1998)
J Cell Biol
, vol.140
, Issue.5
, pp. 1255-1263
-
-
Eliceiri, B.P.1
Klemke, R.2
Stromblad, S.3
Cheresh, D.A.4
-
33
-
-
0035830916
-
Inhibition of angiogenesis by a mouse sprouty protein
-
10.1074/jbc.M006922200, 11053436
-
Lee SH, Schloss DJ, Jarvis L, Krasnow MA, Swain JL. Inhibition of angiogenesis by a mouse sprouty protein. J Biol Chem 2001, 276(6):4128-4133. 10.1074/jbc.M006922200, 11053436.
-
(2001)
J Biol Chem
, vol.276
, Issue.6
, pp. 4128-4133
-
-
Lee, S.H.1
Schloss, D.J.2
Jarvis, L.3
Krasnow, M.A.4
Swain, J.L.5
-
34
-
-
3142780658
-
The expression of Sprouty1, an inhibitor of fibroblast growth factor signal transduction, is decreased in human prostate cancer
-
10.1158/0008-5472.CAN-03-3759, 15256439
-
Kwabi-Addo B, Wang J, Erdem H, Vaid A, Castro P, Ayala G, Ittmann M. The expression of Sprouty1, an inhibitor of fibroblast growth factor signal transduction, is decreased in human prostate cancer. Cancer Res 2004, 64(14):4728-4735. 10.1158/0008-5472.CAN-03-3759, 15256439.
-
(2004)
Cancer Res
, vol.64
, Issue.14
, pp. 4728-4735
-
-
Kwabi-Addo, B.1
Wang, J.2
Erdem, H.3
Vaid, A.4
Castro, P.5
Ayala, G.6
Ittmann, M.7
-
35
-
-
4344660712
-
The ras/mitogen-activated protein kinase pathway inhibitor and likely tumor suppressor proteins, sprouty 1 and sprouty 2 are deregulated in breast cancer
-
10.1158/0008-5472.CAN-04-1207, 15342396
-
Lo TL, Yusoff P, Fong CW, Guo K, McCaw BJ, Phillips WA, Yang H, Wong ES, Leong HF, Zeng Q, et al. The ras/mitogen-activated protein kinase pathway inhibitor and likely tumor suppressor proteins, sprouty 1 and sprouty 2 are deregulated in breast cancer. Cancer Res 2004, 64(17):6127-6136. 10.1158/0008-5472.CAN-04-1207, 15342396.
-
(2004)
Cancer Res
, vol.64
, Issue.17
, pp. 6127-6136
-
-
Lo, T.L.1
Yusoff, P.2
Fong, C.W.3
Guo, K.4
McCaw, B.J.5
Phillips, W.A.6
Yang, H.7
Wong, E.S.8
Leong, H.F.9
Zeng, Q.10
-
36
-
-
33845609555
-
Inhibition of endothelial cell proliferation by Notch1 signaling is mediated by repressing MAPK and PI3K/Akt pathways and requires MAML1
-
10.1096/fj.05-4880fje, 16571776
-
Liu ZJ, Xiao M, Balint K, Soma A, Pinnix CC, Capobianco AJ, Velazquez OC, Herlyn M. Inhibition of endothelial cell proliferation by Notch1 signaling is mediated by repressing MAPK and PI3K/Akt pathways and requires MAML1. Faseb J 2006, 20(7):1009-1011. 10.1096/fj.05-4880fje, 16571776.
-
(2006)
Faseb J
, vol.20
, Issue.7
, pp. 1009-1011
-
-
Liu, Z.J.1
Xiao, M.2
Balint, K.3
Soma, A.4
Pinnix, C.C.5
Capobianco, A.J.6
Velazquez, O.C.7
Herlyn, M.8
-
37
-
-
0036550697
-
Lack of ERK activation and cell migration in FGF-2-deficient endothelial cells
-
Pintucci G, Moscatelli D, Saponara F, Biernacki PR, Baumann FG, Bizekis C, Galloway AC, Basilico C, Mignatti P. Lack of ERK activation and cell migration in FGF-2-deficient endothelial cells. Faseb J 2002, 16(6):598-600.
-
(2002)
Faseb J
, vol.16
, Issue.6
, pp. 598-600
-
-
Pintucci, G.1
Moscatelli, D.2
Saponara, F.3
Biernacki, P.R.4
Baumann, F.G.5
Bizekis, C.6
Galloway, A.C.7
Basilico, C.8
Mignatti, P.9
-
38
-
-
0035933734
-
The C terminus of sprouty is important for modulation of cellular migration and proliferation
-
10.1074/jbc.M100123200, 11279012
-
Yigzaw Y, Cartin L, Pierre S, Scholich K, Patel TB. The C terminus of sprouty is important for modulation of cellular migration and proliferation. J Biol Chem 2001, 276(25):22742-22747. 10.1074/jbc.M100123200, 11279012.
-
(2001)
J Biol Chem
, vol.276
, Issue.25
, pp. 22742-22747
-
-
Yigzaw, Y.1
Cartin, L.2
Pierre, S.3
Scholich, K.4
Patel, T.B.5
-
39
-
-
4444225412
-
Sprouty regulates cell migration by inhibiting the activation of Rac1 GTPase
-
10.1016/j.bbrc.2004.08.070, 15351707
-
Poppleton HM, Edwin F, Jaggar L, Ray R, Johnson LR, Patel TB. Sprouty regulates cell migration by inhibiting the activation of Rac1 GTPase. Biochem Biophys Res Commun 2004, 323(1):98-103. 10.1016/j.bbrc.2004.08.070, 15351707.
-
(2004)
Biochem Biophys Res Commun
, vol.323
, Issue.1
, pp. 98-103
-
-
Poppleton, H.M.1
Edwin, F.2
Jaggar, L.3
Ray, R.4
Johnson, L.R.5
Patel, T.B.6
-
40
-
-
0035958030
-
Erk is essential for growth, differentiation, integrin expression, and cell function in human osteoblastic cells
-
Lai CF, Chaudhary L, Fausto A, Halstead LR, Ory DS, Avioli LV, Cheng SL. Erk is essential for growth, differentiation, integrin expression, and cell function in human osteoblastic cells. J Biol Chem 2001, 276(17):14443-14450.
-
(2001)
J Biol Chem
, vol.276
, Issue.17
, pp. 14443-14450
-
-
Lai, C.F.1
Chaudhary, L.2
Fausto, A.3
Halstead, L.R.4
Ory, D.S.5
Avioli, L.V.6
Cheng, S.L.7
-
41
-
-
33746257300
-
BCR/ABL and IL-3 activate Rap1 to stimulate the B-Raf/MEK/Erk and Akt signaling pathways and to regulate proliferation, apoptosis, and adhesion
-
10.1038/sj.onc.1209459, 16518411
-
Jin A, Kurosu T, Tsuji K, Mizuchi D, Arai A, Fujita H, Hattori M, Minato N, Miura O. BCR/ABL and IL-3 activate Rap1 to stimulate the B-Raf/MEK/Erk and Akt signaling pathways and to regulate proliferation, apoptosis, and adhesion. Oncogene 2006, 25(31):4332-4340. 10.1038/sj.onc.1209459, 16518411.
-
(2006)
Oncogene
, vol.25
, Issue.31
, pp. 4332-4340
-
-
Jin, A.1
Kurosu, T.2
Tsuji, K.3
Mizuchi, D.4
Arai, A.5
Fujita, H.6
Hattori, M.7
Minato, N.8
Miura, O.9
-
42
-
-
41249098474
-
A novel role of Sprouty 2 in regulating cellular apoptosis
-
10.1074/jbc.M706567200, 2527238, 18070883
-
Edwin F, Patel TB. A novel role of Sprouty 2 in regulating cellular apoptosis. J Biol Chem 2008, 283(6):3181-3190. 10.1074/jbc.M706567200, 2527238, 18070883.
-
(2008)
J Biol Chem
, vol.283
, Issue.6
, pp. 3181-3190
-
-
Edwin, F.1
Patel, T.B.2
-
43
-
-
59449086331
-
Sprouty 2 regulates DNA damage-induced apoptosis in Ras-transformed human fibroblasts
-
10.1074/jbc.M808045200, 2613613, 19008219
-
Lito P, Mets BD, Appledorn DM, Maher VM, McCormick JJ. Sprouty 2 regulates DNA damage-induced apoptosis in Ras-transformed human fibroblasts. J Biol Chem 2009, 284(2):848-854. 10.1074/jbc.M808045200, 2613613, 19008219.
-
(2009)
J Biol Chem
, vol.284
, Issue.2
, pp. 848-854
-
-
Lito, P.1
Mets, B.D.2
Appledorn, D.M.3
Maher, V.M.4
McCormick, J.J.5
-
44
-
-
34548721613
-
Sprouty2 inhibits BDNF-induced signaling and modulates neuronal differentiation and survival
-
10.1038/sj.cdd.4402188, 17599098
-
Gross I, Armant O, Benosman S, de Aguilar JL, Freund JN, Kedinger M, Licht JD, Gaiddon C, Loeffler JP. Sprouty2 inhibits BDNF-induced signaling and modulates neuronal differentiation and survival. Cell Death Differ 2007, 14(10):1802-1812. 10.1038/sj.cdd.4402188, 17599098.
-
(2007)
Cell Death Differ
, vol.14
, Issue.10
, pp. 1802-1812
-
-
Gross, I.1
Armant, O.2
Benosman, S.3
de Aguilar, J.L.4
Freund, J.N.5
Kedinger, M.6
Licht, J.D.7
Gaiddon, C.8
Loeffler, J.P.9
-
45
-
-
0033558798
-
VEGF prevents apoptosis of human microvascular endothelial cells via opposing effects on MAPK/ERK and SAPK/JNK signaling
-
10.1006/excr.1998.4359, 10066377
-
Gupta K, Kshirsagar S, Li W, Gui L, Ramakrishnan S, Gupta P, Law PY, Hebbel RP. VEGF prevents apoptosis of human microvascular endothelial cells via opposing effects on MAPK/ERK and SAPK/JNK signaling. Exp Cell Res 1999, 247(2):495-504. 10.1006/excr.1998.4359, 10066377.
-
(1999)
Exp Cell Res
, vol.247
, Issue.2
, pp. 495-504
-
-
Gupta, K.1
Kshirsagar, S.2
Li, W.3
Gui, L.4
Ramakrishnan, S.5
Gupta, P.6
Law, P.Y.7
Hebbel, R.P.8
-
46
-
-
0029786329
-
Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway
-
10.1074/jbc.271.34.20608, 8702807
-
Lavoie JN, L'Allemain G, Brunet A, Muller R, Pouyssegur J. Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway. J Biol Chem 1996, 271(34):20608-20616. 10.1074/jbc.271.34.20608, 8702807.
-
(1996)
J Biol Chem
, vol.271
, Issue.34
, pp. 20608-20616
-
-
Lavoie, J.N.1
L'Allemain, G.2
Brunet, A.3
Muller, R.4
Pouyssegur, J.5
-
47
-
-
0033569726
-
The Raf-1/MEK/ERK pathway regulates the expression of the p21(Cip1/Waf1) gene in chondrocytes
-
10.1074/jbc.274.42.30273, 10514521
-
Beier F, Taylor AC, LuValle P. The Raf-1/MEK/ERK pathway regulates the expression of the p21(Cip1/Waf1) gene in chondrocytes. J Biol Chem 1999, 274(42):30273-30279. 10.1074/jbc.274.42.30273, 10514521.
-
(1999)
J Biol Chem
, vol.274
, Issue.42
, pp. 30273-30279
-
-
Beier, F.1
Taylor, A.C.2
LuValle, P.3
-
48
-
-
13444283563
-
Fibronectin stimulates human lung carcinoma cell proliferation by suppressing p21 gene expression via signals involving Erk and Rho kinase
-
10.1016/j.canlet.2004.07.040, 15694666
-
Han S, Sidell N, Roman J. Fibronectin stimulates human lung carcinoma cell proliferation by suppressing p21 gene expression via signals involving Erk and Rho kinase. Cancer Lett 2005, 219(1):71-81. 10.1016/j.canlet.2004.07.040, 15694666.
-
(2005)
Cancer Lett
, vol.219
, Issue.1
, pp. 71-81
-
-
Han, S.1
Sidell, N.2
Roman, J.3
-
49
-
-
0022590559
-
Effect of fibroblast growth factor and lipoproteins on the proliferation of endothelial cells derived from bovine adrenal cortex, brain cortex, and corpus luteum capillaries
-
10.1002/jcp.1041270116, 3958059
-
Gospodarowicz D, Massoglia S, Cheng J, Fujii DK. Effect of fibroblast growth factor and lipoproteins on the proliferation of endothelial cells derived from bovine adrenal cortex, brain cortex, and corpus luteum capillaries. J Cell Physiol 1986, 127(1):121-136. 10.1002/jcp.1041270116, 3958059.
-
(1986)
J Cell Physiol
, vol.127
, Issue.1
, pp. 121-136
-
-
Gospodarowicz, D.1
Massoglia, S.2
Cheng, J.3
Fujii, D.K.4
-
50
-
-
2442708026
-
Blocking angiogenesis and tumorigenesis with GFA-116, a synthetic molecule that inhibits binding of vascular endothelial growth factor to its receptor
-
10.1158/0008-5472.CAN-03-2673, 15150116
-
Sun J, Blaskovich MA, Jain RK, Delarue F, Paris D, Brem S, Wotoczek-Obadia M, Lin Q, Coppola D, Choi K, et al. Blocking angiogenesis and tumorigenesis with GFA-116, a synthetic molecule that inhibits binding of vascular endothelial growth factor to its receptor. Cancer Res 2004, 64(10):3586-3592. 10.1158/0008-5472.CAN-03-2673, 15150116.
-
(2004)
Cancer Res
, vol.64
, Issue.10
, pp. 3586-3592
-
-
Sun, J.1
Blaskovich, M.A.2
Jain, R.K.3
Delarue, F.4
Paris, D.5
Brem, S.6
Wotoczek-Obadia, M.7
Lin, Q.8
Coppola, D.9
Choi, K.10
-
51
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
10.1006/meth.2001.1262, 11846609
-
Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25(4):402-408. 10.1006/meth.2001.1262, 11846609.
-
(2001)
Methods
, vol.25
, Issue.4
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
|