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Volumn 28, Issue 41, 2010, Pages 6666-6674

CD8+ T cell response in HLA-A*0201 transgenic mice is elicited by epitopes from SARS-CoV S protein

Author keywords

0201; CTL; HLA A; SARS CoV; Vaccine

Indexed keywords

CD45RB ANTIGEN; EPITOPE; GAMMA INTERFERON; HLA A 0201 RESTRICTED PEPTIDE P19; HLA A 0201 RESTRICTED PEPTIDE P20; HLA A 0201 RESTRICTED PEPTIDE P21; HLA A 0201 RESTRICTED PEPTIDE P22; HLA A 0201 RESTRICTED PEPTIDE P23; HLA A ANTIGEN; INTERLEUKIN 2; L SELECTIN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; PEPTIDE; PLASMID DNA; SEVERE ACUTE RESPIRATORY SYNDROME VACCINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 77956478136     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2010.08.013     Document Type: Article
Times cited : (10)

References (43)
  • 1
    • 0038076030 scopus 로고    scopus 로고
    • A novel coronavirus associated with severe acute respiratory syndrome
    • Ksiazek T.G., Erdman D., Goldsmith C.S., Zaki S.R., Peret T., Emery S., et al. A novel coronavirus associated with severe acute respiratory syndrome. N Engl J Med 2003, 348(20):1953-1966.
    • (2003) N Engl J Med , vol.348 , Issue.20 , pp. 1953-1966
    • Ksiazek, T.G.1    Erdman, D.2    Goldsmith, C.S.3    Zaki, S.R.4    Peret, T.5    Emery, S.6
  • 2
    • 0038523806 scopus 로고    scopus 로고
    • Identification of a novel coronavirus in patients with severe acute respiratory syndrome
    • Drosten C., Gunther S., Preiser W., van der Werf S., Brodt H.R., Becker S., et al. Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N Engl J Med 2003, 348(20):1967-1976.
    • (2003) N Engl J Med , vol.348 , Issue.20 , pp. 1967-1976
    • Drosten, C.1    Gunther, S.2    Preiser, W.3    van der Werf, S.4    Brodt, H.R.5    Becker, S.6
  • 3
    • 0242717589 scopus 로고    scopus 로고
    • Coronavirus as a possible cause of severe acute respiratory syndrome
    • Peiris J.S., Lai S.T., Poon L.L., Guan Y., Yam L.Y., Lim W., et al. Coronavirus as a possible cause of severe acute respiratory syndrome. Lancet 2003, 361(9366):1319-1325.
    • (2003) Lancet , vol.361 , Issue.9366 , pp. 1319-1325
    • Peiris, J.S.1    Lai, S.T.2    Poon, L.L.3    Guan, Y.4    Yam, L.Y.5    Lim, W.6
  • 4
    • 2342436435 scopus 로고    scopus 로고
    • Infectious diseases. Mounting lab accidents raise SARS fears
    • Normile D. Infectious diseases. Mounting lab accidents raise SARS fears. Science 2004, 304(5671):659-661.
    • (2004) Science , vol.304 , Issue.5671 , pp. 659-661
    • Normile, D.1
  • 5
    • 1442305466 scopus 로고    scopus 로고
    • Laboratory-acquired SARS raises worries on biosafety
    • Orellana C. Laboratory-acquired SARS raises worries on biosafety. Lancet Infect Dis 2004, 4(2):64.
    • (2004) Lancet Infect Dis , vol.4 , Issue.2 , pp. 64
    • Orellana, C.1
  • 6
    • 5144233232 scopus 로고    scopus 로고
    • SARS virus returns to China as scientists race to find effective vaccine
    • Fleck F. SARS virus returns to China as scientists race to find effective vaccine. Bull World Health Organ 2004, 82(2):152-153.
    • (2004) Bull World Health Organ , vol.82 , Issue.2 , pp. 152-153
    • Fleck, F.1
  • 7
    • 1442329824 scopus 로고    scopus 로고
    • SARS returns to China
    • Paterson R. SARS returns to China. Lancet Infect Dis 2004, 4(2):64.
    • (2004) Lancet Infect Dis , vol.4 , Issue.2 , pp. 64
    • Paterson, R.1
  • 8
    • 0037561920 scopus 로고    scopus 로고
    • Characterization of a novel coronavirus associated with severe acute respiratory syndrome
    • Rota P.A., Oberste M.S., Monroe S.S., Nix W.A., Campagnoli R., Icenogle J.P., et al. Characterization of a novel coronavirus associated with severe acute respiratory syndrome. Science 2003, 300(5624):1394-1399.
    • (2003) Science , vol.300 , Issue.5624 , pp. 1394-1399
    • Rota, P.A.1    Oberste, M.S.2    Monroe, S.S.3    Nix, W.A.4    Campagnoli, R.5    Icenogle, J.P.6
  • 10
    • 2642534316 scopus 로고    scopus 로고
    • S protein of severe acute respiratory syndrome-associated coronavirus mediates entry into hepatoma cell lines and is targeted by neutralizing antibodies in infected patients
    • Hofmann H., Hattermann K., Marzi A., Gramberg T., Geier M., Krumbiegel M., et al. S protein of severe acute respiratory syndrome-associated coronavirus mediates entry into hepatoma cell lines and is targeted by neutralizing antibodies in infected patients. J Virol 2004, 78(12):6134-6142.
    • (2004) J Virol , vol.78 , Issue.12 , pp. 6134-6142
    • Hofmann, H.1    Hattermann, K.2    Marzi, A.3    Gramberg, T.4    Geier, M.5    Krumbiegel, M.6
  • 11
    • 3042714194 scopus 로고    scopus 로고
    • Contributions of the structural proteins of severe acute respiratory syndrome coronavirus to protective immunity
    • Buchholz U.J., Bukreyev A., Yang L., Lamirande E.W., Murphy B.R., Subbarao K., et al. Contributions of the structural proteins of severe acute respiratory syndrome coronavirus to protective immunity. Proc Natl Acad Sci U S A 2004, 101(26):9804-9809.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.26 , pp. 9804-9809
    • Buchholz, U.J.1    Bukreyev, A.2    Yang, L.3    Lamirande, E.W.4    Murphy, B.R.5    Subbarao, K.6
  • 12
    • 33646894897 scopus 로고    scopus 로고
    • Immunization with SARS-CoV S DNA vaccine generates memory CD4+ and CD8+ T cell immune responses
    • Huang J., Ma R., Wu C.Y. Immunization with SARS-CoV S DNA vaccine generates memory CD4+ and CD8+ T cell immune responses. Vaccine 2006, 24(23):4905-4913.
    • (2006) Vaccine , vol.24 , Issue.23 , pp. 4905-4913
    • Huang, J.1    Ma, R.2    Wu, C.Y.3
  • 13
    • 0037440767 scopus 로고    scopus 로고
    • Memory T cells protect chicks from acute infectious bronchitis virus infection
    • Pei J., Briles W.E., Collisson E.W. Memory T cells protect chicks from acute infectious bronchitis virus infection. Virology 2003, 306(2):376-384.
    • (2003) Virology , vol.306 , Issue.2 , pp. 376-384
    • Pei, J.1    Briles, W.E.2    Collisson, E.W.3
  • 14
    • 1842335725 scopus 로고    scopus 로고
    • The carboxyl-terminal 120-residue polypeptide of infectious bronchitis virus nucleocapsid induces cytotoxic T lymphocytes and protects chickens from acute infection
    • Seo S.H., Wang L., Smith R., Collisson E.W. The carboxyl-terminal 120-residue polypeptide of infectious bronchitis virus nucleocapsid induces cytotoxic T lymphocytes and protects chickens from acute infection. J Virol 1997, 71(10):7889-7894.
    • (1997) J Virol , vol.71 , Issue.10 , pp. 7889-7894
    • Seo, S.H.1    Wang, L.2    Smith, R.3    Collisson, E.W.4
  • 15
    • 0036686332 scopus 로고    scopus 로고
    • Virus clearance and immunopathology by CD8(+) T cells during infection with respiratory syncytial virus are mediated by IFN-gamma
    • Ostler T., Davidson W., Ehl S. Virus clearance and immunopathology by CD8(+) T cells during infection with respiratory syncytial virus are mediated by IFN-gamma. Eur J Immunol 2002, 32(8):2117-2123.
    • (2002) Eur J Immunol , vol.32 , Issue.8 , pp. 2117-2123
    • Ostler, T.1    Davidson, W.2    Ehl, S.3
  • 16
    • 0036742233 scopus 로고    scopus 로고
    • Pulmonary T cells induced by respiratory syncytial virus are functional and can make an important contribution to long-lived protective immunity
    • Ostler T., Ehl S. Pulmonary T cells induced by respiratory syncytial virus are functional and can make an important contribution to long-lived protective immunity. Eur J Immunol 2002, 32(9):2562-2569.
    • (2002) Eur J Immunol , vol.32 , Issue.9 , pp. 2562-2569
    • Ostler, T.1    Ehl, S.2
  • 17
    • 33746089516 scopus 로고    scopus 로고
    • Long-lived effector/central memory T-cell responses to severe acute respiratory syndrome coronavirus (SARS-CoV) S antigen in recovered SARS patients
    • Yang L.T., Peng H., Zhu Z.L., Li G., Huang Z.T., Zhao Z.X., et al. Long-lived effector/central memory T-cell responses to severe acute respiratory syndrome coronavirus (SARS-CoV) S antigen in recovered SARS patients. Clin Immunol 2006, 120(2):171-178.
    • (2006) Clin Immunol , vol.120 , Issue.2 , pp. 171-178
    • Yang, L.T.1    Peng, H.2    Zhu, Z.L.3    Li, G.4    Huang, Z.T.5    Zhao, Z.X.6
  • 18
    • 34548565790 scopus 로고    scopus 로고
    • Priming with SARS CoV S DNA and boosting with SARS CoV S epitopes specific for CD4+ and CD8+ T cells promote cellular immune responses
    • Huang J., Cao Y., Du J., Bu X., Ma R., Wu C. Priming with SARS CoV S DNA and boosting with SARS CoV S epitopes specific for CD4+ and CD8+ T cells promote cellular immune responses. Vaccine 2007, 25(39-40):6981-6991.
    • (2007) Vaccine , vol.25 , Issue.39-40 , pp. 6981-6991
    • Huang, J.1    Cao, Y.2    Du, J.3    Bu, X.4    Ma, R.5    Wu, C.6
  • 19
    • 0029897044 scopus 로고    scopus 로고
    • Practical, biochemical and evolutionary implications of the discovery of HLA class I supermotifs
    • Sidney J., Grey H.M., Kubo R.T., Sette A. Practical, biochemical and evolutionary implications of the discovery of HLA class I supermotifs. Immunol Today 1996, 17(6):261-266.
    • (1996) Immunol Today , vol.17 , Issue.6 , pp. 261-266
    • Sidney, J.1    Grey, H.M.2    Kubo, R.T.3    Sette, A.4
  • 20
    • 2542493298 scopus 로고    scopus 로고
    • Association of HLA class I with severe acute respiratory syndrome coronavirus infection
    • Lin M., Tseng H.K., Trejaut J.A., Lee H.L., Loo J.H., Chu C.C., et al. Association of HLA class I with severe acute respiratory syndrome coronavirus infection. BMC Med Genet 2003, 4:9.
    • (2003) BMC Med Genet , vol.4 , pp. 9
    • Lin, M.1    Tseng, H.K.2    Trejaut, J.A.3    Lee, H.L.4    Loo, J.H.5    Chu, C.C.6
  • 21
    • 33646058584 scopus 로고    scopus 로고
    • HLA-A*0201 T-cell epitopes in severe acute respiratory syndrome (SARS) coronavirus nucleocapsid and spike proteins
    • Tsao Y.P., Lin J.Y., Jan J.T., Leng C.H., Chu C.C., Yang Y.C., et al. HLA-A*0201 T-cell epitopes in severe acute respiratory syndrome (SARS) coronavirus nucleocapsid and spike proteins. Biochem Biophys Res Commun 2006, 344(1):63-71.
    • (2006) Biochem Biophys Res Commun , vol.344 , Issue.1 , pp. 63-71
    • Tsao, Y.P.1    Lin, J.Y.2    Jan, J.T.3    Leng, C.H.4    Chu, C.C.5    Yang, Y.C.6
  • 22
    • 3042792364 scopus 로고    scopus 로고
    • Identification of an HLA-A*0201-restricted CD8+ T-cell epitope SSp-1 of SARS-CoV spike protein
    • Wang B., Chen H., Jiang X., Zhang M., Wan T., Li N., et al. Identification of an HLA-A*0201-restricted CD8+ T-cell epitope SSp-1 of SARS-CoV spike protein. Blood 2004, 104(1):200-206.
    • (2004) Blood , vol.104 , Issue.1 , pp. 200-206
    • Wang, B.1    Chen, H.2    Jiang, X.3    Zhang, M.4    Wan, T.5    Li, N.6
  • 23
    • 72549102507 scopus 로고    scopus 로고
    • Identification of a novel conserved HLA-A*0201-restricted epitope from the spike protein of SARS-CoV
    • Lv Y., Ruan Z., Wang L., Ni B., Wu Y. Identification of a novel conserved HLA-A*0201-restricted epitope from the spike protein of SARS-CoV. BMC Immunol 2009, 10:61.
    • (2009) BMC Immunol , vol.10 , pp. 61
    • Lv, Y.1    Ruan, Z.2    Wang, L.3    Ni, B.4    Wu, Y.5
  • 24
    • 33746898241 scopus 로고    scopus 로고
    • Screening and identification of severe acute respiratory syndrome-associated coronavirus-specific CTL epitopes
    • Zhou M., Xu D., Li X., Li H., Shan M., Tang J., et al. Screening and identification of severe acute respiratory syndrome-associated coronavirus-specific CTL epitopes. J Immunol 2006, 177(4):2138-2145.
    • (2006) J Immunol , vol.177 , Issue.4 , pp. 2138-2145
    • Zhou, M.1    Xu, D.2    Li, X.3    Li, H.4    Shan, M.5    Tang, J.6
  • 25
    • 1842589262 scopus 로고    scopus 로고
    • A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice
    • Yang Z.Y., Kong W.P., Huang Y., Roberts A., Murphy B.R., Subbarao K., et al. A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice. Nature 2004, 428(6982):561-564.
    • (2004) Nature , vol.428 , Issue.6982 , pp. 561-564
    • Yang, Z.Y.1    Kong, W.P.2    Huang, Y.3    Roberts, A.4    Murphy, B.R.5    Subbarao, K.6
  • 26
    • 77956469641 scopus 로고    scopus 로고
    • Bioinformatics and molecular analysis section (BIMAS) HLA peptide bingding predictions
    • Taylor R. Bioinformatics and molecular analysis section (BIMAS) HLA peptide bingding predictions ; 2000. http://bimas.dcrt.nih.gov/molbio/hla_bind/index.htm.
    • (2000)
    • Taylor, R.1
  • 28
    • 0037085808 scopus 로고    scopus 로고
    • ALK as a novel lymphoma-associated tumor antigen: identification of 2 HLA-A2.1-restricted CD8+ T-cell epitopes
    • Passoni L., Scardino A., Bertazzoli C., Gallo B., Coluccia A.M., Lemonnier F.A., et al. ALK as a novel lymphoma-associated tumor antigen: identification of 2 HLA-A2.1-restricted CD8+ T-cell epitopes. Blood 2002, 99(6):2100-2106.
    • (2002) Blood , vol.99 , Issue.6 , pp. 2100-2106
    • Passoni, L.1    Scardino, A.2    Bertazzoli, C.3    Gallo, B.4    Coluccia, A.M.5    Lemonnier, F.A.6
  • 29
    • 0033120573 scopus 로고    scopus 로고
    • Utilization of MHC class I transgenic mice for development of minigene DNA vaccines encoding multiple HLA-restricted CTL epitopes
    • Ishioka G.Y., Fikes J., Hermanson G., Livingston B., Crimi C., Qin M., et al. Utilization of MHC class I transgenic mice for development of minigene DNA vaccines encoding multiple HLA-restricted CTL epitopes. J Immunol 1999, 162(7):3915-3925.
    • (1999) J Immunol , vol.162 , Issue.7 , pp. 3915-3925
    • Ishioka, G.Y.1    Fikes, J.2    Hermanson, G.3    Livingston, B.4    Crimi, C.5    Qin, M.6
  • 30
    • 0034602647 scopus 로고    scopus 로고
    • Prophylactic DNA vaccine for hepatitis C virus (HCV) infection: HCV-specific cytotoxic T lymphocyte induction and protection from HCV-recombinant vaccinia infection in an HLA-A2.1 transgenic mouse model
    • Arichi T., Saito T., Major M.E., Belyakov I.M., Shirai M., Engelhard V.H., et al. Prophylactic DNA vaccine for hepatitis C virus (HCV) infection: HCV-specific cytotoxic T lymphocyte induction and protection from HCV-recombinant vaccinia infection in an HLA-A2.1 transgenic mouse model. Proc Natl Acad Sci U S A 2000, 97(1):297-302.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , Issue.1 , pp. 297-302
    • Arichi, T.1    Saito, T.2    Major, M.E.3    Belyakov, I.M.4    Shirai, M.5    Engelhard, V.H.6
  • 31
    • 0032400965 scopus 로고    scopus 로고
    • Lymphotactin gene-modified bone marrow dendritic cells act as more potent adjuvants for peptide delivery to induce specific antitumor immunity
    • Cao X., Zhang W., He L., Xie Z., Ma S., Tao Q., et al. Lymphotactin gene-modified bone marrow dendritic cells act as more potent adjuvants for peptide delivery to induce specific antitumor immunity. J Immunol 1998, 161(11):6238-6244.
    • (1998) J Immunol , vol.161 , Issue.11 , pp. 6238-6244
    • Cao, X.1    Zhang, W.2    He, L.3    Xie, Z.4    Ma, S.5    Tao, Q.6
  • 32
    • 0042123673 scopus 로고    scopus 로고
    • Protracted protection to Plasmodium berghei malaria is linked to functionally and phenotypically heterogeneous liver memory CD8+ T cells
    • Berenzon D., Schwenk R.J., Letellier L., Guebre-Xabier M., Williams J., Krzych U. Protracted protection to Plasmodium berghei malaria is linked to functionally and phenotypically heterogeneous liver memory CD8+ T cells. J Immunol 2003, 171(4):2024-2034.
    • (2003) J Immunol , vol.171 , Issue.4 , pp. 2024-2034
    • Berenzon, D.1    Schwenk, R.J.2    Letellier, L.3    Guebre-Xabier, M.4    Williams, J.5    Krzych, U.6
  • 33
    • 2442684151 scopus 로고    scopus 로고
    • Memory CD8 T-cell differentiation during viral infection
    • Wherry E.J., Ahmed R. Memory CD8 T-cell differentiation during viral infection. J Virol 2004, 78(11):5535-5545.
    • (2004) J Virol , vol.78 , Issue.11 , pp. 5535-5545
    • Wherry, E.J.1    Ahmed, R.2
  • 34
    • 0142185336 scopus 로고    scopus 로고
    • Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation
    • Betts M.R., Brenchley J.M., Price D.A., De Rosa S.C., Douek D.C., Roederer M., et al. Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation. J Immunol Methods 2003, 281(1-2):65-78.
    • (2003) J Immunol Methods , vol.281 , Issue.1-2 , pp. 65-78
    • Betts, M.R.1    Brenchley, J.M.2    Price, D.A.3    De Rosa, S.C.4    Douek, D.C.5    Roederer, M.6
  • 35
    • 1542308572 scopus 로고    scopus 로고
    • Activated primary and memory CD8 T cells migrate to nonlymphoid tissues regardless of site of activation or tissue of origin
    • Masopust D., Vezys V., Usherwood E.J., Cauley L.S., Olson S., Marzo A.L., et al. Activated primary and memory CD8 T cells migrate to nonlymphoid tissues regardless of site of activation or tissue of origin. J Immunol 2004, 172(8):4875-4882.
    • (2004) J Immunol , vol.172 , Issue.8 , pp. 4875-4882
    • Masopust, D.1    Vezys, V.2    Usherwood, E.J.3    Cauley, L.S.4    Olson, S.5    Marzo, A.L.6
  • 36
    • 32444432815 scopus 로고    scopus 로고
    • Cytotoxic T-lymphocyte epitope vaccination protects against human metapneumovirus infection and disease in mice
    • Herd K.A., Mahalingam S., Mackay I.M., Nissen M., Sloots T.P., Tindle R.W. Cytotoxic T-lymphocyte epitope vaccination protects against human metapneumovirus infection and disease in mice. J Virol 2006, 80(4):2034-2044.
    • (2006) J Virol , vol.80 , Issue.4 , pp. 2034-2044
    • Herd, K.A.1    Mahalingam, S.2    Mackay, I.M.3    Nissen, M.4    Sloots, T.P.5    Tindle, R.W.6
  • 37
    • 4143082811 scopus 로고    scopus 로고
    • A candidate vaccine for severe acute respiratory syndrome
    • Johnston R.E. A candidate vaccine for severe acute respiratory syndrome. N Engl J Med 2004, 351(8):827-828.
    • (2004) N Engl J Med , vol.351 , Issue.8 , pp. 827-828
    • Johnston, R.E.1
  • 38
    • 33748847250 scopus 로고    scopus 로고
    • Antigen-specific CD8+ T cells and the development of central memory during Mycobacterium tuberculosis infection
    • Kamath A., Woodworth J.S., Behar S.M. Antigen-specific CD8+ T cells and the development of central memory during Mycobacterium tuberculosis infection. J Immunol 2006, 177(9):6361-6369.
    • (2006) J Immunol , vol.177 , Issue.9 , pp. 6361-6369
    • Kamath, A.1    Woodworth, J.S.2    Behar, S.M.3
  • 39
    • 1842631484 scopus 로고    scopus 로고
    • Immediate cytotoxicity but not degranulation distinguishes effector and memory subsets of CD8+ T cells
    • Wolint P., Betts M.R., Koup R.A., Oxenius A. Immediate cytotoxicity but not degranulation distinguishes effector and memory subsets of CD8+ T cells. J Exp Med 2004, 199(7):925-936.
    • (2004) J Exp Med , vol.199 , Issue.7 , pp. 925-936
    • Wolint, P.1    Betts, M.R.2    Koup, R.A.3    Oxenius, A.4
  • 40
    • 37549012994 scopus 로고    scopus 로고
    • Localization of CD8+ cells specific for hepatitis B virus surface protein in the liver of immunized mice
    • Qu D., Lanier G., Yuan Z.H., Wen Y.M., Howard C.R., Ahmed R. Localization of CD8+ cells specific for hepatitis B virus surface protein in the liver of immunized mice. J Med Virol 2008, 80(2):225-232.
    • (2008) J Med Virol , vol.80 , Issue.2 , pp. 225-232
    • Qu, D.1    Lanier, G.2    Yuan, Z.H.3    Wen, Y.M.4    Howard, C.R.5    Ahmed, R.6
  • 41
    • 0029961635 scopus 로고    scopus 로고
    • Visualization, characterization, and turnover of CD8+ memory T cells in virus-infected hosts
    • Zimmerman C., Brduscha-Riem K., Blaser C., Zinkernagel R.M., Pircher H. Visualization, characterization, and turnover of CD8+ memory T cells in virus-infected hosts. J Exp Med 1996, 183(4):1367-1375.
    • (1996) J Exp Med , vol.183 , Issue.4 , pp. 1367-1375
    • Zimmerman, C.1    Brduscha-Riem, K.2    Blaser, C.3    Zinkernagel, R.M.4    Pircher, H.5
  • 42
    • 0029123526 scopus 로고
    • Distinct phenotypes of antigen-selected CD8 T cells emerge at different stages of an in vivo immune response
    • Walker P.R., Ohteki T., Lopez J.A., MacDonald H.R., Maryanski J.L. Distinct phenotypes of antigen-selected CD8 T cells emerge at different stages of an in vivo immune response. J Immunol 1995, 155(7):3443-3452.
    • (1995) J Immunol , vol.155 , Issue.7 , pp. 3443-3452
    • Walker, P.R.1    Ohteki, T.2    Lopez, J.A.3    MacDonald, H.R.4    Maryanski, J.L.5
  • 43
    • 15044347193 scopus 로고    scopus 로고
    • A strong CD8+ T cell response is elicited using the synthetic polypeptide from the C-terminus of the circumsporozoite protein of Plasmodium berghei together with the adjuvant QS-21: quantitative and phenotypic comparison with the vaccine model of irradiated sporozoites
    • Meraldi V., Romero J.F., Kensil C., Corradin G. A strong CD8+ T cell response is elicited using the synthetic polypeptide from the C-terminus of the circumsporozoite protein of Plasmodium berghei together with the adjuvant QS-21: quantitative and phenotypic comparison with the vaccine model of irradiated sporozoites. Vaccine 2005, 23(21):2801-2812.
    • (2005) Vaccine , vol.23 , Issue.21 , pp. 2801-2812
    • Meraldi, V.1    Romero, J.F.2    Kensil, C.3    Corradin, G.4


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