Controlled swelling and degradation studies of alginate microbeads in dilute natrium citrate solutions;Ispitivanje mogucnosti kontrolisanog bubrenja i razgradnje alginatnih mikrocestica u razblaženim rastvorima natrijum-citrata

Hemijska Industrija

Volumn 64, Issue 4, 2010, Pages 253-263

  Mitrovic, Dragana D ^a,b   Stojkovska, Jasmina J ^a,c   Obradovic, Bojana M ^a,c  

^a Galenika Ad ^*  (Serbia)

^b Galenika Ad   (Serbia)

^c UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

Alginate; Bioreactor with mechanical stimulation; Controlled release; Hydrogel degradation; Swelling

Indexed keywords

EID: 77956458984     PISSN: 0367598X     EISSN: 0350249X     Source Type: Journal    
DOI: 10.2298/HEMIND100302038M     Document Type: Article

References (38)

1. G.T. Grant, E.R. Morris, D.A. Rees, P.J.C. Smith, D. Thom, Biological Interactions Between Polysaccharides and Divalent Cations: The Egg-Box Model, FEBS Letters 32 (1979) 195-198.
2. J.E. Melvik, M. Dornish, in: V. Nedovic, R.G Willaert (Eds.), Focus on Biotechnology: Fundamentals of Cell Immobilisation Biotechnology, Kluwer Academic Publishers, Dordrecht, 2005, pp. 33-53.
3. A.D. Augst, H.J. Kong, D.J. Mooney, Alginate hydrogels as biomaterials, Macromol. Biosci. 6 (2006) 623-633.
4. L. Lum, J. Elisseeff, in: N. Ashammakhi, P. Ferretti (Eds.), Topics in Tissue Engineering, University of Oulu, Oulu, 2003, pp. 1-25.
5. B. Bugarski, B. Amsden, R. Neufeld, D. Poncelet, M.F.A. Goosen, Efect of electrode geometry and charge on the production of polymer by electrostatics, Can. J. Chem. Eng. 72 (1994) 517-522.
6. D. Poncelet, V.G. Babak, R.J. Neufeld, M.F.A. Goosen, B. Bugarski, Theory of electrostatic dispersion of polymer solution in the production of microgel beads containing biocatalyst, Adv. Colloid Interface Sci. 79 (1999) 213-228.
7. V. Manojlovic, B. Obradovic, V. Nedovic, I. Leskosek- Cukalovic, B. Bugarski, Electrostatic generation of alginate microbeads loaded with brewing yeast, Hem. ind. 58 (2004) 62-64.
8. A. Osmokrovic, B. Obradovic, D. Bugarski, B. Bugarski, G. Vunjak-Novakovic, Development of a packed bed bioreactor system aimed for cartilage tissue engineering, FME Trans. 34 (2006) 65-70.
9. B. Obradovic, A. Osmokrovic, B. Bugarski, D. Bugarski, G. Vunjak-Novakovic, Alginate microbeads as cell support for cartilage tissue engineering: bioreactor studies, Mat. Sc. Forum 555 (2007) 417-422.
10. D.E. Orr, K.J.L. Burg, Design of a modular bioreactor to incorporate both perfusion flow and hydrostatic compression for tissue engineering applications, Ann. Biomed. Eng. 36 (2008) 1228-1241.
11. O. Smidrod, G. Skjak-Bræk, Alginate as immobilization matrix for cells, TIBTECH 8 (1990) 71-78.
12. A. B. Lansdown, M. J. Payne, An evaluation of the local reaction and biodegradation of calcium sodium alginate (Kaltostat) following subcutaneous implantation in the rat, J. Roy. Coll. Surg. Edinb. 34 (1994) 284-288.
13. P. Prang, R. Muller, A. Eljaouhari, K. Heckmann, W. Kunz, T. Weber, C. Faber, M. Vroemen, U. Bogdahn, N. Weidner, The promotion of oriented axonal regrowth in the injured spinal cord by alginate-based anisotropic capillary hydrogels, Biomaterials 27 (2006) 3560-3569.
14. R.E.J. Forster, F. Thurmer, C. Wallrapp, A.W. Lloyd, W. Macfarlane, G.J. Phillips, J.-P. Boutrand, A.L. Lewis, Characterisation of physico-mechanical properties and degradation potential of calcium alginate beads for use in embolisation, J. Mater. Sci: Mater. Med. (2010), DOI 10.1007/s10856-010-4080-y
15. P. Sriamornsak, R.A. Kennedy, Effect of a small molecule on diffusion and swelling properties of selected polysaccharide gel beads, Carbohydr. Polym. 79 (2010) 219-223.
16. M. Davidovich-Pinhas, H. Bianco-Peled, A quantitative analysis of alginate swelling, Carbohydr. Polym. 79 (2010) 1020-1027.
17. I. Donati, Y.A. Morch, B.L. Strand, G. Skjak-Bræk, S. Paoletti, Effect of elongation of alternating sequences on swelling behavior and large deformation properties of natural alginate gels, J. Phys. Chem. B 113 (2009) 12916-12922.
18. H.J. Kong, K.Y. Lee, D.J. Mooney, Nondestructively probing the cross-linking density of polymeric hydrogels, Macromolecules 36 (2003) 7887-7890.
19. 2+ on water solubility, particle release and swelling properties of magnetic alginate films, J. Magn. Magn. Mater. 305 (2006) 221-227.
20. 2+ ions, React. Funct. Polym. 59 (2004) 129-140.
21. J. Qin, Gel swelling properties of alginate fibers, J. Appl. Polymer. Sci. 91 (2004) 1641-1645.
22. V. Pillay, R. Fassihi, In vitro release modulation from crosslinked pellets for site-specific drug delivery to the gastrointestinal tract I. Comparison of pH-responsive drug release and associated kinetics, J. Control. Release 59 (1999) 229-242.
23. A. Rajendran, S.K. Basu, Alginate-chitosan particulate system for sustained release of nimodipine, Trop. J. Pharm. Res. 8 (2009) 433-440.
24. M.M. Elnashar, M.A. Yassin, A.E.-F.A. Moneim, E.M.A. Bary, Surprising performance of alginate beads for the release of low-molecular-weight drugs, J. Appl. Polym. Sci. 116 (2010) 3021-3026.
25. J. Zhang, Q. Wang, A. Wang, In situ generation of sodium alginate/hydroxyapatite nanocomposite beads as drug-controlled release matrices, Acta Biomater. 6 (2010) 445-454.
26. J.L. Doublier, B. Launay, G. Cuvelier, in: M.A Rao, J.F Steffe (Eds.), Viscoelastic properties of food, Elsevier Applied Science, London, 1992, pp. 371-434.
27. M. Mancini, M. Moresi, R. Rancini, Mechanical properties of alginate gels: empirical characterization, J. Food Eng. 39 (1999) 369-378.
28. M. Mancini, M. Moresi, R. Rancini, Uniaxial compression and relaxation tests on alginate gels, J. Texture. Stud. 30 (1999) 639-657.
29. M.A. LeRoux, F. Guilak, L.A. Setton, Compressive and shear properties of alginate gel: effects of sodium ions and alginate concentration, J. Biomed. Mater. Res. 47 (1999) 46-53.
30. J. Stojkovska, B. Bugarski, B. Obradovic, u: Knjiga apstrakata, Osma konferencija mladih istraživaca Nauka i inženjerstvo novih materijala, Beograd, 2009, p. 22.
31. V.A. Nedović, B. Obradovic, C.I. Leskošek., O. Trifunovic, R. Pešic, B. Bugarski, Electrostatic generation of alginate microbeads loaded with brewing yeast, Process Biochem. 37 (2001) 17-22.
32. V. Manojlovic, N. Rajic, J. Djonlagic, B. Obradovic, V. Nedovic, B. Bugarski, Application of electrostatic extrusion - flavour encapsulation and controlled release, Sensors 8 (2008) 1488-1496.
33. B. Obradovic, D. Bugarski, M. Petakov, G. Jovcic, N. Stojanovic, B. Bugarski, G. Vunjak-Novakovic, Cell support studies aimed for cartilage tissue engineering in perfused bioreactors, Mat. Sc. Forum. 453-454 (2004) 549-554.
34. M. Petrovic, D. Mitrakovic, B. Bugarski, D. Vonwil, I. Martin, B. Obradovic, A novel bioreactor with mechanical stimulation for skeletal tissue engineering, Chem. Ind. Chem. Eng. Q. 15 (2009) 41-44.
35. D. Bugarski, B. Obradovic, M. Petakov, G. Jovcic, N. Stojanovic, B. Bugarski, Alginate Microbeads as Potential Support for Cultivation of Bone Marrow Stromal Cells, Mat. Sci. Forum 494 (2005) 525-530.
36. A. Osmokrovic, Razvoj bioreaktorskog sistema sa pakovanim slojem alginatnih mikrocestica za bioinženjering tkiva hrskavice, Multidisciplinarne postdiplomske studije, Univerzitet u Beogradu, 2009.
37. 3 microparticle composite gel structures, Chem. Eng. J. 145 (2009) 514-521.
38. M.M. Stevens, H.F. Qanadilo, R. Langer, V.P. Shastri, A rapid-curing alginate gel system: utility in periosteumderived cartilage tissue engineering, Biomaterials 25 (2004) 887-894.