메뉴 건너뛰기




Volumn 38, Issue 5, 2010, Pages 995-1004

Tanshinone IIA increases mRNA expression of efflux transporters in cultured human intestinal cell

Author keywords

Bioavailability; Caco 2 Cell; Tanshinone IIA; Transporter

Indexed keywords

MESSENGER RNA; TANSHINONE IIA;

EID: 77956450390     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X1000841X     Document Type: Article
Times cited : (9)

References (33)
  • 1
    • 0031977003 scopus 로고    scopus 로고
    • Drug exsorption from blood into the gastrointestinal tract
    • Arimori, K. and M. Nakano. Drug exsorption from blood into the gastrointestinal tract. Pharm. Res. 15: 371-376, 1998.
    • (1998) Pharm. Res. , vol.15 , pp. 371-376
    • Arimori, K.1    Nakano, M.2
  • 2
    • 0025804183 scopus 로고
    • Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells
    • Artursson, P. and J. Karlsson. Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells. Biochem. Biophys. Res. Commun. 175: 880-885, 1991.
    • (1991) Biochem. Biophys. Res. Commun. , vol.175 , pp. 880-885
    • Artursson, P.1    Karlsson, J.2
  • 3
    • 70449409308 scopus 로고    scopus 로고
    • The role of ABC transporters in protecting cells from bilirubin toxicity
    • Bellarosa, C., G. Bortolussi and C. Tiribelli. The role of ABC transporters in protecting cells from bilirubin toxicity. Curr. Pharm. Des. 15: 2884-2892, 2009.
    • (2009) Curr. Pharm. Des. , vol.15 , pp. 2884-2892
    • Bellarosa, C.1    Bortolussi, G.2    Tiribelli, C.3
  • 4
    • 33751301012 scopus 로고    scopus 로고
    • Pharmacophore-based discovery of ligands for drug transporters
    • Chang, C., S. Ekins, P. Bahadduri and P.W. Swaan. Pharmacophore-based discovery of ligands for drug transporters. Adv. Drug Deliv. Rev. 58: 1431-1450, 2006.
    • (2006) Adv. Drug Deliv. Rev. , vol.58 , pp. 1431-1450
    • Chang, C.1    Ekins, S.2    Bahadduri, P.3    Swaan, P.W.4
  • 5
    • 45949101019 scopus 로고    scopus 로고
    • Prediction of oral drug absorption in humans-from cultured cell lines and experimental animals
    • Cheng, K.C., C. Li and A.S. Uss. Prediction of oral drug absorption in humans-from cultured cell lines and experimental animals. Expert Opin. Drug Metab. Toxicol. 4: 581-590, 2008.
    • (2008) Expert Opin. Drug Metab. Toxicol. , vol.4 , pp. 581-590
    • Cheng, K.C.1    Li, C.2    Uss, A.S.3
  • 6
    • 62549108159 scopus 로고    scopus 로고
    • ABC transporters, drug resistance, and cancer stem cells
    • Dean, M. ABC transporters, drug resistance, and cancer stem cells. J. Mammary Gland Biol. Neoplasia 14: 3-9, 2009.
    • (2009) J. Mammary Gland Biol. Neoplasia , vol.14 , pp. 3-9
    • Dean, M.1
  • 7
    • 24644488751 scopus 로고    scopus 로고
    • The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis
    • Elsharkawy, A.M., F. Oakley and D.A. Mann. The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis. Apoptosis 10: 927-939, 2005.
    • (2005) Apoptosis , vol.10 , pp. 927-939
    • Elsharkawy, A.M.1    Oakley, F.2    Mann., D.A.3
  • 8
    • 33750723755 scopus 로고    scopus 로고
    • Testosterone increases lactate transport, monocarboxylate transporter (MCT) 1 and MCT4 in rat skeletal muscle
    • Enoki, T., Y. Yoshida, J. Lally, H. Hatta and A. Bonen. Testosterone increases lactate transport, monocarboxylate transporter (MCT) 1 and MCT4 in rat skeletal muscle. J. Physiol. 577: 433-443, 2006.
    • (2006) J. Physiol. , vol.577 , pp. 433-443
    • Enoki, T.1    Yoshida, Y.2    Lally, J.3    Hatta, H.4    Bonen., A.5
  • 9
    • 0035662969 scopus 로고    scopus 로고
    • MCT1-mediated transport of L-lactic acid at the inner blood-retinal barrier: A possible route for delivery of monocarboxylic acid drugs to the retina
    • Hosoya, K., T. Kondo, M. Tomi, H. Takanaga, S. Ohtsuki and T. Terasaki. MCT1-mediated transport of L-lactic acid at the inner blood-retinal barrier: a possible route for delivery of monocarboxylic acid drugs to the retina. Pharm. Res. 18: 1669-1676, 2001.
    • (2001) Pharm. Res. , vol.18 , pp. 1669-1676
    • Hosoya, K.1    Kondo, T.2    Tomi, M.3    Takanaga, H.4    Ohtsuki, S.5    Terasaki, T.6
  • 10
    • 0043212075 scopus 로고    scopus 로고
    • Biological, pharmaceutical, and analytical considerations with respect to the transport media used in the absorption screening system
    • Ingels, F.M. and P.F. Augustijns. Biological, pharmaceutical, and analytical considerations with respect to the transport media used in the absorption screening system, Caco-2. J. Pharm. Sci. 92: 1545-1558, 2003.
    • (2003) Caco-2. J. Pharm. Sci. , vol.92 , pp. 1545-1558
    • Ingels, F.M.1    Augustijns, P.F.2
  • 11
    • 67349162433 scopus 로고    scopus 로고
    • Tanshinone IIA sodium sulfonate protects against cardiotoxicity induced by doxorubicin in vitro and in vitro
    • Jiang, B., L. Zhang, Y. Wang, M. Li, W. Wu, S. Guan, X. Liu, M. Yang, J. Wang and D.A. Guo. Tanshinone IIA sodium sulfonate protects against cardiotoxicity induced by doxorubicin in vitro and in vitro. Food Chem. Toxicol. 47: 1538-1544, 2009.
    • (2009) Food Chem. Toxicol. , vol.47 , pp. 1538-1544
    • Jiang, B.1    Zhang, L.2    Wang, Y.3    Li, M.4    Wu, W.5    Guan, S.6    Liu, X.7    Yang, M.8    Wang, J.9    Guo, D.A.10
  • 12
    • 0031838805 scopus 로고    scopus 로고
    • CDNA cloning and inducible expression of human multidrug resistance associated protein 3 (MRP3)
    • Kiuchi, Y., H. Suzuki, T. Hirohashi, C.A. Tyson and Y. Sugiyama. cDNA cloning and inducible expression of human multidrug resistance associated protein 3 (MRP3). FEBS Lett. 433: 149-152, 1998.
    • (1998) FEBS Lett. , vol.433 , pp. 149-152
    • Kiuchi, Y.1    Suzuki, H.2    Hirohashi, T.3    Tyson, C.A.4    Sugiyama, Y.5
  • 13
    • 18644378003 scopus 로고    scopus 로고
    • Expression and localization of human multidrugy resistance protein (ABCC) family members in pancreatic carcinoma
    • Konig, J., M. Hartel, A.T. Nies, M.E. Martignoni, J. Guo, M.W. Buchler, H. Friess and D. Keppler. Expression and localization of human multidrugy resistance protein (ABCC) family members in pancreatic carcinoma. Int. J. Cancer 115: 359-367, 2005.
    • (2005) Int. J. Cancer , vol.115 , pp. 359-367
    • Konig, J.1    Hartel, M.2    Nies, A.T.3    Martignoni, M.E.4    Guo, J.5    Buchler, M.W.6    Friess, H.7    Keppler., D.8
  • 14
    • 35649009910 scopus 로고    scopus 로고
    • Intestinal permeability and its relevance for absorption and elimination
    • Lennernas, H. Intestinal permeability and its relevance for absorption and elimination. Xenobiotica 37: 1015-1051, 2007.
    • (2007) Xenobiotica , vol.37 , pp. 1015-1051
    • Lennernas, H.1
  • 15
    • 35349007415 scopus 로고    scopus 로고
    • Situ intestinal absorption behaviors of Tanshinone IIA from its inclusion complex with hydroxypropyl-beta-cyclodextrin
    • Ling, W., L.C. Rui and J.X. Hua. In situ intestinal absorption behaviors of Tanshinone IIA from its inclusion complex with hydroxypropyl-beta- cyclodextrin. Biol. Pharm. Bull. 30: 1918-1922, 2007.
    • (2007) Biol. Pharm. Bull. , vol.30 , pp. 1918-1922
    • Ling, W.1    Rui, L.C.2    Hua, J.X.3
  • 16
    • 47949093788 scopus 로고    scopus 로고
    • Plasma and urinary tanshinol from Salvia miltiorrhiza (Danshen) can be used as pharmacokinetic markers for cardiotonic pills, a cardiovascular herbal medicine
    • Lu, T., J. Yang, X. Gao, P. Chen, F. Du, Y. Sun, F. Wang, F. Xu, H. Shang, Y. Huang, Y. Wang, R. Wan, C. Liu, B. Zhang and C. Li. Plasma and urinary tanshinol from Salvia miltiorrhiza (Danshen) can be used as pharmacokinetic markers for cardiotonic pills, a cardiovascular herbal medicine. Drug Metab. Dispos. 36: 1578-1586, 2008.
    • (2008) Drug Metab. Dispos. , vol.36 , pp. 1578-1586
    • Lu, T.1    Yang, J.2    Gao, X.3    Chen, P.4    Du, F.5    Sun, Y.6    Wang, F.7    Xu, F.8    Shang, H.9    Huang, Y.10    Wang, Y.11    Wan, R.12    Liu, C.13    Zhang, B.14    Li, C.15
  • 17
    • 0028786481 scopus 로고
    • The human intestinal epithelial cell line Caco-2; Pharmacological and pharmacokinetic applications
    • Meunier, V., M. Bourrié, Y. Berger and G. Fabre. The human intestinal epithelial cell line Caco-2; pharmacological and pharmacokinetic applications. Cell Biol. Toxicol. 11: 187-194, 1995.
    • (1995) Cell Biol. Toxicol. , vol.11 , pp. 187-194
    • Meunier, V.1    Bourrié, M.2    Berger, Y.3    Fabre, G.4
  • 18
    • 63349094264 scopus 로고    scopus 로고
    • Drug transport across the blood-brain barrier and the impact of breast cancer resistance protein (ABCG2)
    • Nicolazzo, J.A. and K. Katneni. Drug transport across the blood-brain barrier and the impact of breast cancer resistance protein (ABCG2). Curr. Top. Med. Chem. 9: 130-147, 2009.
    • (2009) Curr. Top. Med. Chem. , vol.9 , pp. 130-147
    • Nicolazzo, J.A.1    Katneni, K.2
  • 19
    • 61749098274 scopus 로고    scopus 로고
    • The biological and clinical role of drug transporters at the intestinal barrier
    • Oostendorp, R.L., J.H. Beijnen and J.H. Schellens. The biological and clinical role of drug transporters at the intestinal barrier. Cancer Treat. Rev. 35: 137-147, 2009.
    • (2009) Cancer Treat. Rev. , vol.35 , pp. 137-147
    • Oostendorp, R.L.1    Beijnen, J.H.2    Schellens, J.H.3
  • 20
    • 64649100965 scopus 로고    scopus 로고
    • Drug transport mechanism of the AcrB efflux pump
    • Pos, K.M. Drug transport mechanism of the AcrB efflux pump. Biochim. Biophys. Acta 1794: 782-793, 2009.
    • (2009) Biochim. Biophys. Acta , vol.1794 , pp. 782-793
    • Pos, K.M.1
  • 21
    • 60749091589 scopus 로고    scopus 로고
    • Permeability for intestinal absorption: Caco-2 assay and related issues
    • Press, B. and D. Di Grandi. Permeability for intestinal absorption: Caco-2 assay and related issues. Curr. Drug Metab. 9: 893-900, 2008.
    • (2008) Curr. Drug Metab. , vol.9 , pp. 893-900
    • Press, B.1    Di Grandi, D.2
  • 22
    • 41349107158 scopus 로고    scopus 로고
    • Multidrug resistance protein 4 (MRP4/ ABCC4): A versatile efflux transporter for drugs and signaling molecules
    • Russel, F.G., J.B. Koenderink and R. Masereeuw. Multidrug resistance protein 4 (MRP4/ ABCC4): a versatile efflux transporter for drugs and signaling molecules. Trends Pharmacol. Sci. 29: 200-207, 2008.
    • (2008) Trends Pharmacol. Sci. , vol.29 , pp. 200-207
    • Russel, F.G.1    Koenderink, J.B.2    Masereeuw, R.3
  • 24
    • 64649090980 scopus 로고    scopus 로고
    • Molecular basis of multidrug transport by ABC transporters
    • Seeger, M.A. and H.W. van Veen. Molecular basis of multidrug transport by ABC transporters. Biochim. Biophys. Acta 1794: 725-737, 2009.
    • (2009) Biochim. Biophys. Acta , vol.1794 , pp. 725-737
    • Seeger, M.A.1    Van Veen, H.W.2
  • 25
    • 13444288036 scopus 로고    scopus 로고
    • Breast cancer resistance protein (BCRP/ABCG2)
    • Staud, F. and P. Pavek. Breast cancer resistance protein (BCRP/ABCG2). Int. J. Biochem. Cell Biol. 37: 720-725, 2005.
    • (2005) Int. J. Biochem. Cell Biol. , vol.37 , pp. 720-725
    • Staud, F.1    Pavek, P.2
  • 26
    • 2942750350 scopus 로고    scopus 로고
    • ATP-binding cassette (ABC) transporters in human metabolism and diseases
    • Stefkova, J., R. Poledne and J.A. Hubacek. ATP-binding cassette (ABC) transporters in human metabolism and diseases. Physiol. Res. 53: 235-243, 2004.
    • (2004) Physiol. Res. , vol.53 , pp. 235-243
    • Stefkova, J.1    Poledne, R.2    Hubacek, J.A.3
  • 27
    • 0028786196 scopus 로고
    • Effects of hypoxic endothelial cell conditioned medium on proliferation and collagen synthesis of smooth muscle cells and inhibitory effects of radix salviae miltiorrhizae
    • Sun, B., Y. Yuan, W. Zhang and D. Che. Effects of hypoxic endothelial cell conditioned medium on proliferation and collagen synthesis of smooth muscle cells and inhibitory effects of radix salviae miltiorrhizae. Chin. Med. J. 108: 855-858, 1995.
    • (1995) Chin. Med. J. , vol.108 , pp. 855-858
    • Sun, B.1    Yuan, Y.2    Zhang, W.3    Che, D.4
  • 28
    • 33745748312 scopus 로고    scopus 로고
    • The functions and structure of ABC transporters: Implications for the design of new inhibitors of Pgp and MRP1 to control multidrug resistance (MDR)
    • Teodori, E., S. Dei, C. Martelli, S. Scapecchi and F. Gualtieri. The functions and structure of ABC transporters: implications for the design of new inhibitors of Pgp and MRP1 to control multidrug resistance (MDR). Curr. Drug Targets 7: 893-909, 2006.
    • (2006) Curr. Drug Targets , vol.7 , pp. 893-909
    • Teodori, E.1    Dei, S.2    Martelli, C.3    Scapecchi, S.4    Gualtieri., F.5
  • 29
  • 30
    • 69949127756 scopus 로고    scopus 로고
    • Mutagenesis and cysteine scanning of transmembrane domain 10 of the human dipeptide transporter
    • Xu, L., I.S. Haworth, A.A. Kulkarni. M.B. Bolger and D.L. Davies. Mutagenesis and cysteine scanning of transmembrane domain 10 of the human dipeptide transporter. Pharm. Res. 26: 2358-2366, 2009.
    • (2009) Pharm. Res. , vol.26 , pp. 2358-2366
    • Xu, L.1    Haworth, I.S.2    Kulkarni, M.B.3    Bolger, A.A.4    Davies, D.L.5
  • 31
    • 36949010980 scopus 로고    scopus 로고
    • Multidrug resistance associated proteins as determining factors of pharmacokinetics and pharmacodynamics of drugs
    • Yu, X.Q., C.C. Xue, G. Wang and S.F. Zhou. Multidrug resistance associated proteins as determining factors of pharmacokinetics and pharmacodynamics of drugs. Curr. Drug Metab. 8: 787-802, 2007.
    • (2007) Curr. Drug Metab. , vol.8 , pp. 787-802
    • Yu, X.Q.1    Xue, C.C.2    Wang, G.3    Zhou, S.F.4
  • 32
    • 53349117254 scopus 로고    scopus 로고
    • Substrates and inhibitors of human multidrug resistance associated proteins and the implications in drug development
    • Zhou, S.F., L.L. Wang, Y.M. Di, C.C. Xue, W. Duan, C.G. Li and Y. Li. Substrates and inhibitors of human multidrug resistance associated proteins and the implications in drug development. Curr. Med. Chem. 15: 1981-2039, 2008.
    • (2008) Curr. Med. Chem. , vol.15 , pp. 1981-2039
    • Zhou, S.F.1    Wang, L.L.2    Di, Y.M.3    Xue, C.C.4    Duan, W.5    Li, C.G.6    Li, Y.7
  • 33
    • 13444252326 scopus 로고    scopus 로고
    • Mapping of multidrug resistance gene 1 and multidrug resistance- associated protein isoform 1 to 5 mRNA expression along the human intestinal tract
    • Zimmermann, C., H. Gutmann, P. Hruz, J.P. Gutzwiller, C. Beglinger and J. Drewe. Mapping of multidrug resistance gene 1 and multidrug resistance-associated protein isoform 1 to 5 mRNA expression along the human intestinal tract. Drug Metab. Dispos. 33: 219-224, 2005.
    • (2005) Drug Metab. Dispos. , vol.33 , pp. 219-224
    • Zimmermann, C.1    Gutmann, H.2    Hruz, P.3    Gutzwiller, J.P.4    Beglinger, C.5    Drewe, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.