Physiological definition of upper airway obstructions in mouse model for Rett syndrome

Respiratory Physiology and Neurobiology

Volumn 173, Issue 2, 2010, Pages 146-156

  Voituron, Nicolas ^a   Menuet, Clément ^a   Dutschmann, Mathias ^a,b   Hilaire, Gérard ^a  

^a University of Mediterranée   (France)

^b UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

EMG; MeCP2; Obstructive apnoeas; Plethysmography; Upper airway

Indexed keywords

METHYL CPG BINDING PROTEIN 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; APNEA; ARTICLE; ELECTROMYOGRAM; LUNG VENTILATION; MALE; MOUSE; NONHUMAN; PLETHYSMOGRAPHY; PRIORITY JOURNAL; RESPIRATION LOAD; RESPIRATORY AIRFLOW; RESPIRATORY FUNCTION; RETT SYNDROME; SPIROGRAPHY; UPPER RESPIRATORY TRACT OBSTRUCTION;

AGE FACTORS; AIRWAY OBSTRUCTION; ANIMALS; DISEASE MODELS, ANIMAL; ELECTROMYOGRAPHY; MALE; METHYL-CPG-BINDING PROTEIN 2; MICE; MICE, KNOCKOUT; PLETHYSMOGRAPHY; PULMONARY VENTILATION; RESPIRATORY MECHANICS; RESPIRATORY MUSCLES; RETT SYNDROME;

EID: 77956435735     PISSN: 15699048     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.resp.2010.07.006     Document Type: Article

References (51)

1. Abdala A.P., Dutschmann M., Bissonnette J.M., Paton J.F. Suppression of expiratory activity in a mouse model of Rett syndrome follows blockade of GABA reuptake and activation of serotonin type 1a receptors. FASEB J. 2010, 24. 613.9.
2. Abdala A.P., Rybak I.A., Smith J.C., Zoccal D.B., Machado B.H., St-John W.M., Paton J.F. Multiple pontomedullary mechanisms of respiratory rhythmogenesis. Respir. Physiol. Neurobiol. 2009, 168:19-25.
3. Adachi M., Autry A.E., Covington H.E., Monteggia L.M. MeCP2-mediated transcription repression in the basolateral amygdala may underlie heightened anxiety in a mouse model of Rett syndrome. J. Neurosci. 2009, 29:4218-4227.
4. Amiel J., Dubreuil V., Ramanantsoa N., Fortin G., Gallego J., Brunet J.F., Goridis C. PHOX2B in respiratory control: lessons from congenital central hypoventilation syndrome and its mouse models. Respir. Physiol. Neurobiol. 2009, 168:125-132.
5. Amir R.E., Van den Veyver I.B., Wan M., Tran C.Q., Francke U., Zoghbi H.Y. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat. Genet. 1999, 23:185-188.
6. Angell-James J.E., Elsner R., De Burgh Daly M. Lung inflation: effects on heart rate, respiration, and vagal afferent activity in seals. Am. J. Physiol. 1981, 240:H190-H198.
7. Baekey D.M., Feng P., Decker M.J., Strohl K.P. Breathing and sleep: measurement methods, genetic influences, and developmental impacts. ILAR J. 2009, 50:248-261.
8. Bianchi A.L., Gestreau C. The brainstem respiratory network: an overview of a half century of research. Respir. Physiol. Neurobiol. 2009, 168:4-12.
9. Budden S., Meek M., Henighan C. Communication and oral-motor function in Rett syndrome. Dev. Med. Child Neurol. 1990, 32:51-55.
10. Butler P.J., Jones D.R. Physiology of diving of birds and mammals. Physiol. Rev. 1997, 77:837-899.
11. Dutschmann M., Paton J.F. Inhibitory synaptic mechanisms regulating upper airway patency. Respir. Physiol. Neurobiol. 2002, 131:57-63.
12. Dutschmann M., Paton J.F. Influence of nasotrigeminal afferents on medullary respiratory neurones and upper airway patency in the rat. Pflugers Arch. 2002, 444:227-235.
13. Dutschmann M., Morschel M., Reuter J., Zhang W., Gestreau C., Stettner G.M., Kron M. Postnatal emergence of synaptic plasticity associated with dynamic adaptation of the respiratory motor pattern. Respir. Physiol. Neurobiol. 2008, 164:72-79.
14. Dutschmann M., Morschel M., Rybak I.A., Dick T.E. Learning to breathe: control of the inspiratory-expiratory phase transition shifts from sensory- to central-dominated during postnatal development in rats. J. Physiol. 2009, 587:4931-4948.
15. Dutschmann M., Menuet C., Stettner G.M., Gestreau C., Borghgraef P., Devijver H., Gielis L., Hilaire G., Van Leuven F. Upper airway dysfunction of Tau-P301L mice correlates with tauopathy in midbrain and ponto-medullary brainstem nuclei. J. Neurosci. 2010, 30:1810-1821.
16. Feldman J.L., Del Negro C.A. Looking for inspiration: new perspectives on respiratory rhythm. Nat. Rev. Neurosci. 2006, 7:232-242.
17. Fyffe S.L., Neul J.L., Samaco R.C., Chao H.T., Ben-Shachar S., Moretti P., McGill B.E., Goulding E.H., Sullivan E., Tecott L.H., Zoghbi H.Y. Deletion of Mecp2 in Sim1-expressing neurons reveals a critical role for MeCP2 in feeding behavior, aggression, and the response to stress. Neuron 2008, 59:947-958.
18. Gaultier C., Gallego J. Neural control of breathing: insights from genetic mouse models. J. Appl. Physiol. 2008, 104:1522-1530.
19. Gray P.A. Transcription factors and the genetic organization of brain stem respiratory neurons. J. Appl. Physiol. 2008, 104:1513-1521.
20. Guy J., Hendrich B., Holmes M., Martin J.E., Bird A. A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome. Nat. Genet. 2001, 27:322-326.
21. Hilaire G., Duron B. Maturation of the mammalian respiratory system. Physiol. Rev. 1999, 79:325-360.
22. Holstege G., Bandler R., Saper C.B. The emotional motor system. Prog. Brain Res. 1996, 107:3-6.
23. Ide S., Itoh M., Goto Y. Defect in normal developmental increase of the brain biogenic amine concentrations in the mecp2-null mouse. Neurosci. Lett. 2005, 386:14-17.
24. Katz D.M., Dutschmann M., Ramirez J.M., Hilaire G. Breathing disorders in Rett syndrome: progressive neurochemical dysfunction in the respiratory network after birth. Respir. Physiol. Neurobiol. 2009, 168:101-108.
25. Kurihara M., Kumagai K., Nakae Y. Effect of diazepam on apnea attacks in a 6-year-old girl with Rett syndrome: a polysomnographic study. No To Hattatsu 2001, 33:58-62.
26. McCulloch P.F., Dinovo K.M., Connolly T.M. The cardiovascular and endocrine responses to voluntary and forced diving in trained and untrained rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2010, 298:R224-R234.
27. McGill B.E., Bundle S.F., Yaylaoglu M.B., Carson J.P., Thaller C., Zoghbi H.Y. Enhanced anxiety and stress-induced corticosterone release are associated with increased Crh expression in a mouse model of Rett syndrome. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:18267-18272.
28. Medrihan L., Tantalaki E., Aramuni G., Sargsyan V., Dudanova I., Missler M., Zhang W. Early defects of GABAergic synapses in the brain stem of a MeCP2 mouse model of Rett syndrome. J. Neurophysiol. 2008, 99:112-121.
29. Morschel M., Dutschmann M. Pontine respiratory activity involved in inspiratory/expiratory phase transition. Philos. Trans. R. Soc. Lond. B: Biol. Sci. 2009, 364:2517-2526.
30. Morton R.E., Bonas R., Minford J., Kerr A., Ellis R.E. Feeding ability in Rett syndrome. Dev. Med. Child Neurol. 1997, 39:331-335.
31. Morton R.E., Bonas R., Minford J., Tarrant S.C., Ellis R.E. Respiration patterns during feeding in Rett syndrome. Dev. Med. Child Neurol. 1997, 39:607-613.
32. Motil K.J., Schultz R.J., Browning K., Trautwein L., Glaze D.G. Oropharyngeal dysfunction and gastroesophageal dysmotility are present in girls and women with Rett syndrome. J. Pediatr. Gastroenterol. Nutr. 1999, 29:31-37.
33. Ogier M., Katz D.M. Breathing dysfunction in Rett syndrome: understanding epigenetic regulation of the respiratory network. Respir. Physiol. Neurobiol. 2008, 164:55-63.
34. Onimaru H., Homma I. A novel functional neuron group for respiratory rhythm generation in the ventral medulla. J. Neurosci. 2003, 23:1478-1486.
35. Onimaru H., Ikeda K., Kawakami K. Phox2b, RTN/pFRG neurons and respiratory rhythmogenesis. Respir. Physiol. Neurobiol. 2009, 168:13-18.
36. Perry A., Sarlo-McGarvey N., Factor D.C. Stress and family functioning in parents of girls with Rett syndrome. J. Autism Dev. Disord. 1992, 22:235-248.
37. Reves J.G., Fragen R.J., Vinik H.R., Greenblatt D.J. Midazolam: pharmacology and uses. Anesthesiology 1985, 62:310-324.
38. Roux J.C., Panayotis N., Dura E., Villard L. Progressive noradrenergic deficits in the locus coeruleus of Mecp2 deficient mice. J. Neurosci. Res. 2009.
39. Shiba K., Satoh I., Kobayashi N., Hayashi F. Multifunctional laryngeal motoneurons: an intracellular study in the cat. J. Neurosci. 1999, 19:2717-2727.
40. Smith J.C., Abdala A.P., Koizumi H., Rybak I.A., Paton J.F. Spatial and functional architecture of the mammalian brain stem respiratory network: a hierarchy of three oscillatory mechanisms. J. Neurophysiol. 2007, 98:3370-3387.
41. Smith J.C., Abdala A.P., Rybak I.A., Paton J.F. Structural and functional architecture of respiratory networks in the mammalian brainstem. Philos. Trans. R. Soc. Lond. B: Biol. Sci. 2009, 364:2577-2587.
42. -/y knockout mice. J. Physiol. 2007, 579:863-876.
43. Stettner G.M., Zanella S., Huppke P., Gartner J., Hilaire G., Dutschmann M. Spontaneous central apneas occur in the C57BL/6J mouse strain. Respir. Physiol. Neurobiol. 2008, 160:21-27.
44. Sun Q.J., Berkowitz R.G., Pilowsky P.M. GABA A mediated inhibition and post-inspiratory pattern of laryngeal constrictor motoneurons in rat. Respir. Physiol. Neurobiol. 2008, 162:41-47.
45. Taneja P., Ogier M., Brooks-Harris G., Schmid D.A., Katz D.M., Nelson S.B. Pathophysiology of locus ceruleus neurons in a mouse model of Rett syndrome. J. Neurosci. 2009, 29:12187-12195.
46. Thoby-Brisson M., Karlen M., Wu N., Charnay P., Champagnat J., Fortin G. Genetic identification of an embryonic parafacial oscillator coupling to the preBotzinger complex. Nat. Neurosci. 2009, 12:1028-1035.
47. Viemari J.C., Roux J.C., Tryba A.K., Saywell V., Burnet H., Pena F., Zanella S., Bevengut M., Barthelemy-Requin M., Herzing L.B., Moncla A., Mancini J., Ramirez J.M., Villard L., Hilaire G. Mecp2 deficiency disrupts norepinephrine and respiratory systems in mice. J. Neurosci. 2005, 25:11521-11530.
48. Voituron N., Zanella S., Menuet C., Dutschmann M., Hilaire G. Early breathing defects after moderate hypoxia or hypercapnia in a mouse model of Rett syndrome. Respir. Physiol. Neurobiol. 2009, 168:109-118.
49. Voituron N., Zanella S., Menuet C., Lajard A.M., Dutschmann M., Hilaire G. Early abnormalities of post-sigh breathing in a mouse model of Rett syndrome. Respir. Physiol. Neurobiol. 2010, 170:173-182.
50. Wu S.H., Camarena V. MeCP2 function in the basolateral amygdala in Rett syndrome. J. Neurosci. 2009, 29:9941-9942.
51. Zanella S., Mebarek S., Lajard A.M., Picard N., Dutschmann M., Hilaire G. Oral treatment with desipramine improves breathing and life span in Rett syndrome mouse model. Respir. Physiol. Neurobiol. 2008, 160:116-121.