Oral treatment with desipramine improves breathing and life span in Rett syndrome mouse model

Respiratory Physiology and Neurobiology

Volumn 160, Issue 1, 2008, Pages 116-121

  Zanella, Sébastien ^a   Mebarek, Saida ^a   Lajard, Anne Marie ^a   Picard, Nathalie ^a   Dutschmann, Mathias ^b   Hilaire, Gérard ^a  

^a CNRS   (France)

^b Deutsche Forschungsgemeinschaft   (Germany)

Author keywords

Control of breathing; Desipramine; Disease; Mecp2 KO mice; Mice; Norepinephrine; Pharmacology; Rett Syndrome; Treatment

Indexed keywords

DESIPRAMINE; METHYL CPG BINDING PROTEIN 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREATHING; C57BL 6 MOUSE; CONTROLLED STUDY; DRUG EFFECT; LIFESPAN; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; RETT SYNDROME; STATISTICAL SIGNIFICANCE; SYMPTOM;

ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; APNEA; DESIPRAMINE; FEMALE; LOCOMOTION; LONGEVITY; MEDULLA OBLONGATA; METHYL-CPG-BINDING PROTEIN 2; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROCEPHALY; NOREPINEPHRINE; PLETHYSMOGRAPHY; RESPIRATORY MECHANICS; RETT SYNDROME;

EID: 36849075300     PISSN: 15699048     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.resp.2007.08.009     Document Type: Article

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