-
1
-
-
0034597794
-
Telomere states and cell fates
-
10.1038/35040500. 11081503
-
Telomere states and cell fates. E Blackburn, Nature 2000 408 6808 53 56 10.1038/35040500 11081503
-
(2000)
Nature
, vol.408
, Issue.6808
, pp. 53-56
-
-
Blackburn, E.1
-
2
-
-
0025731583
-
Structure and function of telomeres
-
10.1038/350569a0. 1708110
-
Structure and function of telomeres. EH Blackburn, Nature 1991 350 6319 569 573 10.1038/350569a0 1708110
-
(1991)
Nature
, vol.350
, Issue.6319
, pp. 569-573
-
-
Blackburn, E.H.1
-
3
-
-
0025279931
-
Telomeres shorten during ageing of human fibroblasts
-
10.1038/345458a0. 2342578
-
Telomeres shorten during ageing of human fibroblasts. CB Harley AB Futcher CW Greider, Nature 1990 345 6274 458 460 10.1038/345458a0 2342578
-
(1990)
Nature
, vol.345
, Issue.6274
, pp. 458-460
-
-
Harley, C.B.1
Futcher, A.B.2
Greider, C.W.3
-
4
-
-
0028564951
-
Specific association of human telomerase activity with immortal cells and cancer
-
10.1126/science.7605428. 7605428
-
Specific association of human telomerase activity with immortal cells and cancer. NW Kim MA Piatyszek KR Prowse CB Harley MD West PL Ho GM Coviello WE Wright SL Weinrich JW Shay, Science 1994 266 5193 2011 2015 10.1126/science. 7605428 7605428
-
(1994)
Science
, vol.266
, Issue.5193
, pp. 2011-2015
-
-
Kim, N.W.1
Piatyszek, M.A.2
Prowse, K.R.3
Harley, C.B.4
West, M.D.5
Ho, P.L.6
Coviello, G.M.7
Wright, W.E.8
Weinrich, S.L.9
Shay, J.W.10
-
5
-
-
22444447447
-
Novel antitumor and neuroprotective substances discovered by characteristic screenings based on specific molecular targets
-
10.1271/bbb.69.867. 15914903
-
Novel antitumor and neuroprotective substances discovered by characteristic screenings based on specific molecular targets. K Shin-Ya, Biosci Biotechnol Biochem 2005 69 5 867 872 10.1271/bbb.69.867 15914903
-
(2005)
Biosci Biotechnol Biochem
, vol.69
, Issue.5
, pp. 867-872
-
-
Shin-Ya, K.1
-
6
-
-
0346336773
-
Telomerase inhibition with an oligonucleotide telomerase template antagonist: In vitro and in vivo studies in multiple myeloma and lymphoma
-
10.1182/blood-2003-02-0546. 12969977
-
Telomerase inhibition with an oligonucleotide telomerase template antagonist: in vitro and in vivo studies in multiple myeloma and lymphoma. ES Wang K Wu AC Chin S Chen-Kiang K Pongracz S Gryaznov MA Moore, Blood 2004 103 1 258 266 10.1182/blood-2003-02-0546 12969977
-
(2004)
Blood
, vol.103
, Issue.1
, pp. 258-266
-
-
Wang, E.S.1
Wu, K.2
Chin, A.C.3
Chen-Kiang, S.4
Pongracz, K.5
Gryaznov, S.6
Moore, M.A.7
-
7
-
-
0037359032
-
Evolution of target specificity in R1 clade non-LTR retrotransposons
-
10.1093/molbev/msg031. 12644555
-
Evolution of target specificity in R1 clade non-LTR retrotransposons. K Kojima H Fujiwara, Mol Biol Evol 2003 20 3 351 361 10.1093/molbev/msg031 12644555
-
(2003)
Mol Biol Evol
, vol.20
, Issue.3
, pp. 351-361
-
-
Kojima, K.1
Fujiwara, H.2
-
8
-
-
0029069498
-
Structural analysis of TRAS1, a novel family of telomeric repeat-associated retrotransposons in the silkworm, Bombyx mori
-
7623845
-
Structural analysis of TRAS1, a novel family of telomeric repeat-associated retrotransposons in the silkworm, Bombyx mori. S Okazaki H Ishikawa H Fujiwara, Mol Cell Biol 1995 15 8 4545 4552 7623845
-
(1995)
Mol Cell Biol
, vol.15
, Issue.8
, pp. 4545-4552
-
-
Okazaki, S.1
Ishikawa, H.2
Fujiwara, H.3
-
9
-
-
0034747801
-
Sequence-specific recognition and cleavage of telomeric repeat (TTAGG)(n) by endonuclease of non-long terminal repeat retrotransposon TRAS1
-
10.1128/MCB.21.1.100-108.2001. 11113185
-
Sequence-specific recognition and cleavage of telomeric repeat (TTAGG)(n) by endonuclease of non-long terminal repeat retrotransposon TRAS1. T Anzai H Takahashi H Fujiwara, Mol Cell Biol 2001 21 1 100 108 10.1128/MCB.21.1.100-108. 2001 11113185
-
(2001)
Mol Cell Biol
, vol.21
, Issue.1
, pp. 100-108
-
-
Anzai, T.1
Takahashi, H.2
Fujiwara, H.3
-
10
-
-
0036470563
-
Transplantation of target site specificity by swapping the endonuclease domains of two LINEs
-
10.1093/emboj/21.3.408. 11823433
-
Transplantation of target site specificity by swapping the endonuclease domains of two LINEs. H Takahashi H Fujiwara, EMBO J 2002 21 3 408 417 10.1093/emboj/21.3.408 11823433
-
(2002)
EMBO J
, vol.21
, Issue.3
, pp. 408-417
-
-
Takahashi, H.1
Fujiwara, H.2
-
11
-
-
4644364681
-
Crystal structure of the endonuclease domain encoded by the telomere-specific long interspersed nuclear element, TRAS1
-
10.1074/jbc.M406556200. 15247245
-
Crystal structure of the endonuclease domain encoded by the telomere-specific long interspersed nuclear element, TRAS1. N Maita T Anzai H Aoyagi H Mizuno H Fujiwara, J Biol Chem 2004 279 39 41067 41076 10.1074/jbc.M406556200 15247245
-
(2004)
J Biol Chem
, vol.279
, Issue.39
, pp. 41067-41076
-
-
Maita, N.1
Anzai, T.2
Aoyagi, H.3
Mizuno, H.4
Fujiwara, H.5
-
12
-
-
34547624835
-
Characterization of the sequence specificity of the R1Bm endonuclease domain by structural and biochemical studies
-
10.1093/nar/gkm397. 17537809
-
Characterization of the sequence specificity of the R1Bm endonuclease domain by structural and biochemical studies. N Maita H Aoyagi M Osanai M Shirakawa H Fujiwara, Nucleic Acids Res 2007 35 12 3918 3927 10.1093/nar/gkm397 17537809
-
(2007)
Nucleic Acids Res
, vol.35
, Issue.12
, pp. 3918-3927
-
-
Maita, N.1
Aoyagi, H.2
Osanai, M.3
Shirakawa, M.4
Fujiwara, H.5
-
13
-
-
0032478313
-
Retrotransposon R1Bm endonuclease cleaves the target sequence
-
10.1073/pnas.95.5.2083. 9482842
-
Retrotransposon R1Bm endonuclease cleaves the target sequence. Q Feng G Schumann J Boeke, Proc Natl Acad Sci USA 1998 95 5 2083 2088 10.1073/pnas.95.5.2083 9482842
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.5
, pp. 2083-2088
-
-
Feng, Q.1
Schumann, G.2
Boeke, J.3
-
14
-
-
33745278855
-
Computational redesign of endonuclease DNA binding and cleavage specificity
-
10.1038/nature04818. 16738662
-
Computational redesign of endonuclease DNA binding and cleavage specificity. J Ashworth JJ Havranek CM Duarte D Sussman RJ Monnat Jr BL Stoddard D Baker, Nature 2006 441 7093 656 659 10.1038/nature04818 16738662
-
(2006)
Nature
, vol.441
, Issue.7093
, pp. 656-659
-
-
Ashworth, J.1
Havranek, J.J.2
Duarte, C.M.3
Sussman, D.4
Monnat Jr., R.J.5
Stoddard, B.L.6
Baker, D.7
-
15
-
-
34547873144
-
Determinants for DNA target structure selectivity of the human LINE-1 retrotransposon endonuclease
-
10.1093/nar/gkm516. 17626046
-
Determinants for DNA target structure selectivity of the human LINE-1 retrotransposon endonuclease. K Repanas N Zingler L Layer G Schumann A Perrakis O Weichenrieder, Nucleic Acids Res 2007 35 14 4914 4926 10.1093/nar/gkm516 17626046
-
(2007)
Nucleic Acids Res
, vol.35
, Issue.14
, pp. 4914-4926
-
-
Repanas, K.1
Zingler, N.2
Layer, L.3
Schumann, G.4
Perrakis, A.5
Weichenrieder, O.6
-
16
-
-
84984775429
-
Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2
-
10.1038/ng1097-231. 9326950
-
Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2. D Broccoli A Smogorzewska L Chong T de Lange, Nat Genet 1997 17 2 231 235 10.1038/ng1097-231 9326950
-
(1997)
Nat Genet
, vol.17
, Issue.2
, pp. 231-235
-
-
Broccoli, D.1
Smogorzewska, A.2
Chong, L.3
De Lange, T.4
-
17
-
-
0031027618
-
Control of telomere length by the human telomeric protein TRF1
-
10.1038/385740a0. 9034193
-
Control of telomere length by the human telomeric protein TRF1. B van Steensel T de Lange, Nature 1997 385 6618 740 743 10.1038/385740a0 9034193
-
(1997)
Nature
, vol.385
, Issue.6618
, pp. 740-743
-
-
Van Steensel, B.1
De Lange, T.2
-
18
-
-
0030032063
-
Hybrid restriction enzymes: Zinc finger fusions to FokI cleavage domain
-
10.1073/pnas.93.3.1156. 8577732
-
Hybrid restriction enzymes: zinc finger fusions to FokI cleavage domain. YG Kim J Cha S Chandrasegaran, Proc Natl Acad Sci USA 1996 93 3 1156 1160 10.1073/pnas.93.3.1156 8577732
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, Issue.3
, pp. 1156-1160
-
-
Kim, Y.G.1
Cha, J.2
Chandrasegaran, S.3
-
19
-
-
0034788744
-
Design of the linkers which effectively separate domains of a bifunctional fusion protein
-
10.1093/protein/14.8.529. 11579220
-
Design of the linkers which effectively separate domains of a bifunctional fusion protein. R Arai H Ueda A Kitayama N Kamiya T Nagamune, Protein Eng 2001 14 8 529 532 10.1093/protein/14.8.529 11579220
-
(2001)
Protein Eng
, vol.14
, Issue.8
, pp. 529-532
-
-
Arai, R.1
Ueda, H.2
Kitayama, A.3
Kamiya, N.4
Nagamune, T.5
-
20
-
-
0027398943
-
Alteration of the cleavage distance of FokI restriction endonuclease by insertion mutagenesis
-
10.1073/pnas.90.7.2764. 8464886
-
Alteration of the cleavage distance of FokI restriction endonuclease by insertion mutagenesis. L Li S Chandrasegaran, Proc Natl Acad Sci USA 1993 90 7 2764 2768 10.1073/pnas.90.7.2764 8464886
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, Issue.7
, pp. 2764-2768
-
-
Li, L.1
Chandrasegaran, S.2
-
21
-
-
0031013459
-
Comparison of the human and mouse genes encoding the telomeric protein, TRF1: Chromosomal localization, expression and conserved protein domains
-
10.1093/hmg/6.1.69. 9002672
-
Comparison of the human and mouse genes encoding the telomeric protein, TRF1: chromosomal localization, expression and conserved protein domains. D Broccoli L Chong S Oelmann A Fernald N Marziliano B van Steensel D Kipling M Le Beau T de Lange, Hum Mol Genet 1997 6 1 69 76 10.1093/hmg/6.1.69 9002672
-
(1997)
Hum Mol Genet
, vol.6
, Issue.1
, pp. 69-76
-
-
Broccoli, D.1
Chong, L.2
Oelmann, S.3
Fernald, A.4
Marziliano, N.5
Van Steensel, B.6
Kipling, D.7
Le Beau, M.8
De Lange, T.9
-
22
-
-
0042420304
-
DNA damage foci at dysfunctional telomeres
-
10.1016/S0960-9822(03)00542-6. 12956959
-
DNA damage foci at dysfunctional telomeres. H Takai A Smogorzewska T de Lange, Curr Biol 2003 13 17 1549 1556 10.1016/S0960-9822(03)00542-6 12956959
-
(2003)
Curr Biol
, vol.13
, Issue.17
, pp. 1549-1556
-
-
Takai, H.1
Smogorzewska, A.2
De Lange, T.3
-
23
-
-
0034749425
-
DNA damage-dependent nuclear dynamics of the Mre11 complex
-
10.1128/MCB.21.1.281-288.2001. 11113202
-
DNA damage-dependent nuclear dynamics of the Mre11 complex. O Mirzoeva J Petrini, Mol Cell Biol 2001 21 1 281 288 10.1128/MCB.21.1.281-288.2001 11113202
-
(2001)
Mol Cell Biol
, vol.21
, Issue.1
, pp. 281-288
-
-
Mirzoeva, O.1
Petrini, J.2
-
24
-
-
26444602415
-
P16INK4a as a second effector of the telomere damage pathway
-
16177573
-
p16INK4a as a second effector of the telomere damage pathway. J Jacobs T de Lange, Cell Cycle 2005 4 10 1364 1368 16177573
-
(2005)
Cell Cycle
, vol.4
, Issue.10
, pp. 1364-1368
-
-
Jacobs, J.1
De Lange, T.2
-
25
-
-
44349136891
-
Telomere dysfunction and tumour suppression: The senescence connection
-
10.1038/nrc2393. 18500246
-
Telomere dysfunction and tumour suppression: the senescence connection. Y Deng S Chan S Chang, Nat Rev Cancer 2008 8 6 450 458 10.1038/nrc2393 18500246
-
(2008)
Nat Rev Cancer
, vol.8
, Issue.6
, pp. 450-458
-
-
Deng, Y.1
Chan, S.2
Chang, S.3
-
26
-
-
2942569579
-
Telomere-bound TRF1 and TRF2 stall the replication fork at telomeric repeats
-
10.1093/nar/gkh309. 15007108
-
Telomere-bound TRF1 and TRF2 stall the replication fork at telomeric repeats. R Ohki F Ishikawa, Nucleic Acids Res 2004 32 5 1627 1637 10.1093/nar/gkh309 15007108
-
(2004)
Nucleic Acids Res
, vol.32
, Issue.5
, pp. 1627-1637
-
-
Ohki, R.1
Ishikawa, F.2
-
27
-
-
35548993664
-
Catalytic domain of restriction endonuclease BmrI as a cleavage module for engineering endonucleases with novel substrate specificities
-
10.1093/nar/gkm665. 17855396
-
Catalytic domain of restriction endonuclease BmrI as a cleavage module for engineering endonucleases with novel substrate specificities. S Chan Y Bao E Ciszak S Laget S Xu, Nucleic Acids Res 2007 35 18 6238 6248 10.1093/nar/gkm665 17855396
-
(2007)
Nucleic Acids Res
, vol.35
, Issue.18
, pp. 6238-6248
-
-
Chan, S.1
Bao, Y.2
Ciszak, E.3
Laget, S.4
Xu, S.5
-
28
-
-
47349097567
-
Rapid 'open-source' engineering of customized zinc-finger nucleases for highly efficient gene modification
-
10.1016/j.molcel.2008.06.016. 18657511
-
Rapid 'open-source' engineering of customized zinc-finger nucleases for highly efficient gene modification. ML Maeder S Thibodeau-Beganny A Osiak DA Wright RM Anthony M Eichtinger T Jiang JE Foley RJ Winfrey JA Townsend E Unger-Wallace JD Sander F Müller-Lerch F Fu J Pearlberg C Göbel JP Dassie SM Pruett-Miller MH Porteus DC Sgroi AJ Iafrate D Dobbs PB McCray Jr T Cathomen DF Voytas JK Joung, Mol Cell 2008 31 2 294 301 10.1016/j.molcel.2008. 06.016 18657511
-
(2008)
Mol Cell
, vol.31
, Issue.2
, pp. 294-301
-
-
Maeder, M.L.1
Thibodeau-Beganny, S.2
Osiak, A.3
Wright, D.A.4
Anthony, R.M.5
Eichtinger, M.6
Jiang, T.7
Foley, J.E.8
Winfrey, R.J.9
Townsend, J.A.10
Unger-Wallace, E.11
Sander, J.D.12
Muller-Lerch, F.13
Fu, F.14
Pearlberg, J.15
Gobel, C.16
Dassie, J.P.17
Pruett- Miller, S.M.18
Porteus, M.H.19
Sgroi, D.C.20
Iafrate, A.J.21
Dobbs, D.22
McCray Jr., P.B.23
Cathomen, T.24
Voytas, D.F.25
Joung, J.K.26
more..
-
29
-
-
38549136058
-
Custom-designed zinc finger nucleases: What is next?
-
10.1007/s00018-007-7206-8. 17763826
-
Custom-designed zinc finger nucleases: what is next? J Wu K Kandavelou S Chandrasegaran, Cell Mol Life Sci 2007 64 22 2933 2944 10.1007/s00018-007-7206-8 17763826
-
(2007)
Cell Mol Life Sci
, vol.64
, Issue.22
, pp. 2933-2944
-
-
Wu, J.1
Kandavelou, K.2
Chandrasegaran, S.3
-
30
-
-
55549129245
-
Progress and prospects: Zinc-finger nucleases as gene therapy agents
-
10.1038/gt.2008.145. 18784746
-
Progress and prospects: zinc-finger nucleases as gene therapy agents. D Carroll, Gene Ther 2008 15 22 1463 1468 10.1038/gt.2008.145 18784746
-
(2008)
Gene Ther
, vol.15
, Issue.22
, pp. 1463-1468
-
-
Carroll, D.1
-
31
-
-
0037350830
-
Telomerase inhibition enhances apoptosis in human acute leukemia cells: Possibility of antitelomerase therapy
-
10.1038/sj.leu.2402825. 12646945
-
Telomerase inhibition enhances apoptosis in human acute leukemia cells: possibility of antitelomerase therapy. A Nakajima T Tauchi G Sashida M Sumi K Abe K Yamamoto J Ohyashiki K Ohyashiki, Leukemia 2003 17 3 560 567 10.1038/sj.leu.2402825 12646945
-
(2003)
Leukemia
, vol.17
, Issue.3
, pp. 560-567
-
-
Nakajima, A.1
Tauchi, T.2
Sashida, G.3
Sumi, M.4
Abe, K.5
Yamamoto, K.6
Ohyashiki, J.7
Ohyashiki, K.8
-
32
-
-
50549093286
-
Gene transfer: The challenge of regulated gene expression
-
10.1016/j.molmed.2008.07.003. 18692441
-
Gene transfer: the challenge of regulated gene expression. Z Guo Q Li D Bartlett J Yang B Fang, Trends Mol Med 2008 14 9 410 418 10.1016/j.molmed.2008. 07.003 18692441
-
(2008)
Trends Mol Med
, vol.14
, Issue.9
, pp. 410-418
-
-
Guo, Z.1
Li, Q.2
Bartlett, D.3
Yang, J.4
Fang, B.5
-
33
-
-
0034604552
-
Sequence-specific DNA recognition by the Myb-like domain of plant telomeric protein RTBP1
-
10.1074/jbc.M003250200. 10811811
-
Sequence-specific DNA recognition by the Myb-like domain of plant telomeric protein RTBP1. EY Yu SE Kim JH Kim JH Ko MH Cho IK Chung, J Biol Chem 2000 275 31 24208 24214 10.1074/jbc.M003250200 10811811
-
(2000)
J Biol Chem
, vol.275
, Issue.31
, pp. 24208-24214
-
-
Yu, E.Y.1
Kim, S.E.2
Kim, J.H.3
Ko, J.H.4
Cho, M.H.5
Chung, I.K.6
-
34
-
-
0031055468
-
Construction of adenovirus vectors through Cre-lox recombination
-
9032314
-
Construction of adenovirus vectors through Cre-lox recombination. S Hardy M Kitamura T Harris-Stansil Y Dai M Phipps, J Virol 1997 71 3 1842 1849 9032314
-
(1997)
J Virol
, vol.71
, Issue.3
, pp. 1842-1849
-
-
Hardy, S.1
Kitamura, M.2
Harris-Stansil, T.3
Dai, Y.4
Phipps, M.5
-
35
-
-
33845792555
-
CellProfiler: Image analysis software for identifying and quantifying cell phenotypes
-
10.1186/gb-2006-7-10-r100. 17076895
-
CellProfiler: image analysis software for identifying and quantifying cell phenotypes. AE Carpenter TR Jones MR Lamprecht C Clarke IH Kang O Friman DA Guertin JH Chang RA Lindquist J Moffat P Golland DM Sabatini, Genome Biol 2006 7 10 100 10.1186/gb-2006-7-10-r100 17076895
-
(2006)
Genome Biol
, vol.7
, Issue.10
, pp. 18100
-
-
Carpenter, A.E.1
Jones, T.R.2
Lamprecht, M.R.3
Clarke, C.4
Kang, I.H.5
Friman, O.6
Guertin, D.A.7
Chang, J.H.8
Lindquist, R.A.9
Moffat, J.10
Golland, P.11
Sabatini, D.M.12
-
36
-
-
0029047362
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
-
10.1073/pnas.92.20.9363. 7568133
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo. G Dimri X Lee G Basile M Acosta G Scott C Roskelley E Medrano M Linskens I Rubelj O Pereira-Smith, Proc Natl Acad Sci USA 1995 92 20 9363 9367 10.1073/pnas.92.20.9363 7568133
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, Issue.20
, pp. 9363-9367
-
-
Dimri, G.1
Lee, X.2
Basile, G.3
Acosta, M.4
Scott, G.5
Roskelley, C.6
Medrano, E.7
Linskens, M.8
Rubelj, I.9
Pereira-Smith, O.10
|