Suppression of homodimerization of toll-like receptor 4 by isoliquiritigenin

Phytochemistry

Volumn 71, Issue 14-15, 2010, Pages 1736-1740

  Park, Se Jeong ^a   Youn, Hyung Sun ^a  

^a Soonchunhyang University   (South Korea)

Author keywords

Dimerization; Isoliquiritigenin; Lipopolysaccharide; NF B; Toll like receptors

Indexed keywords

CHALCONE DERIVATIVE; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERFERON REGULATORY FACTOR 3; IRF3 PROTEIN, HUMAN; ISOLIQUIRITIGENIN; LIPOPOLYSACCHARIDE; TOLL LIKE RECEPTOR 4;

ANIMAL; ARTICLE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; GLYCYRRHIZA; HUMAN; MACROPHAGE; METABOLISM; MOUSE; PLANT ROOT;

ANIMALS; CHALCONES; CYCLOOXYGENASE 2; GLYCYRRHIZA; HUMANS; INTERFERON REGULATORY FACTOR-3; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PLANT ROOTS; TOLL-LIKE RECEPTOR 4;

GLYCYRRHIZA;

EID: 77956345011     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phytochem.2010.07.008     Document Type: Article

References (30)

1. S.I. Ahn, J.K. Lee, and H.S. Youn Inhibition of homodimerization of toll-like receptor 4 by 6-shogaol Mol. Cells 27 2009 211 215
2. S. Akira, and K. Takeda Toll-like receptor signalling Nat. Rev. Immunol. 4 2004 499 511
3. Z. Cao, W.J. Henzel, and X. Gao IRAK: a kinase associated with the interleukin-1 receptor Science 271 1996 1128 1131
4. V. Fintelmann Modern phytotherapy and its uses in gastrointestinal conditions Planta Med. 57 1991 S48 S52
5. Hacker, H., Karin, M., 2006. Regulation and function of IKK and IKK-related kinases. Sci. STKE 2006, re13.
6. E.G. Haggag, M.A. Abou-Moustafa, W. Boucher, and T.C. Theoharides The effect of a herbal water-extract on histamine release from mast cells and on allergic asthma J. Herb. Pharmacother. 3 2003 41 54
7. K. Hoebe, X. Du, P. Georgel, E. Janssen, K. Tabeta, S.O. Kim, J. Goode, P. Lin, N. Mann, S. Mudd, K. Crozat, S. Sovath, J. Han, and B. Beutler Identification of Lps2 as a key transducer of MyD88-independent TIR signalling Nature 424 2003 743 748
8. H. Kakegawa, H. Matsumoto, and T. Satoh Inhibitory effects of some natural products on the activation of hyaluronidase and their anti-allergic actions Chem. Pharm. Bull. (Tokyo) 40 1992 1439 1442
9. T. Kawai, and S. Akira Signaling to NF-kappaB by toll-like receptors Trends Mol. Med. 13 2007 460 469
10. S. Kumar, A. Sharma, B. Madan, V. Singhal, and B. Ghosh Isoliquiritigenin inhibits IkappaB kinase activity and ROS generation to block TNF-alpha induced expression of cell adhesion molecules on human endothelial cells Biochem. Pharmacol. 73 2007 1602 1612
11. R. Medzhitov, P. Preston-Hurlburt, and C.A. Janeway Jr. A human homologue of the Drosophila toll protein signals activation of adaptive immunity Nature 388 1997 394 397
12. H.K. Na, and Y.J. Surh Transcriptional regulation via cysteine thiol modification: a novel molecular strategy for chemoprevention and cytoprotection Mol. Carcinog. 45 2006 368 380
13. C. Ospelt, and S. Gay TLRs and chronic inflammation Int. J. Biochem. Cell Biol. 42 2009 495 505
14. S.J. Park, H.Y. Song, and H.S. Youn Suppression of the TRIF-dependent signaling pathway of toll-like receptors by isoliquiritigenin in RAW264.7 macrophages Mol. Cells. 28 2009 365 368
15. S.J. Park, S.M. Yun, A.N. Lee, S.I. Ahn, M.Y. Lee, and H.S. Youn Costunolide inhibits cyclooxygenase-2 expression induced by Toll-like receptor 3 or 4 agonist Toxicol. Environ. Health Sci. 1 2009 122 126
16. S. Saitoh, S. Akashi, T. Yamada, N. Tanimura, M. Kobayashi, K. Konno, F. Matsumoto, K. Fukase, S. Kusumoto, Y. Nagai, Y. Kusumoto, A. Kosugi, and K. Miyake Lipid A antagonist, lipid IVa, is distinct from lipid A in interaction with Toll-like receptor 4 (TLR4)-MD-2 and ligand-induced TLR4 oligomerization Int. Immunol. 16 2004 961 969
17. N. Suzuki, S. Ohno, T. Kamei, Y. Yoshiki, Y. Kikuchi, K. Okubo, T. Ohta, S. Shimizu, S. Koshimura, A. Taru, and M. Inoue Complementary and alternative medicine in Japan Adv. Exp. Med. Biol. 546 2004 9 25
18. T. Takahashi, N. Takasuka, M. Iigo, M. Baba, H. Nishino, H. Tsuda, and T. Okuyama Isoliquiritigenin, a flavonoid from licorice, reduces prostaglandin E2 and nitric oxide, causes apoptosis, and suppresses aberrant crypt foci development Cancer Sci. 95 2004 448 453
19. K. Takeda, and S. Akira Microbial recognition by Toll-like receptors J. Dermatol. Sci. 34 2004 73 82
20. K. Takeda, and S. Akira Toll-like receptors in innate immunity Int. Immunol. 17 2005 1 14
21. K. Takeda, T. Kaisho, and S. Akira Toll-like receptors Annu. Rev. Immunol. 21 2003 335 376
22. S. Tamir, M. Eizenberg, D. Somjen, S. Izrael, and J. Vaya Estrogen-like activity of glabrene and other constituents isolated from licorice root J. Steroid. Biochem. Mol. Biol. 78 2001 291 298
23. M. Tawata, K. Aida, T. Noguchi, Y. Ozaki, S. Kume, H. Sasaki, M. Chin, and T. Onaya Anti-platelet action of isoliquiritigenin, an aldose reductase inhibitor in licorice Eur. J. Pharmacol. 212 1992 87 92
24. J. Vaya, P.A. Belinky, and M. Aviram Antioxidant constituents from licorice roots: isolation, structure elucidation and antioxidative capacity toward LDL oxidation Free Radic. Biol. Med. 23 1997 302 313
25. M. Yamamoto, S. Sato, H. Hemmi, K. Hoshino, T. Kaisho, H. Sanjo, O. Takeuchi, M. Sugiyama, M. Okabe, K. Takeda, and S. Akira Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway Science 301 2003 640 643
26. H.S. Youn, J.Y. Lee, S.I. Saitoh, K. Miyake, and D.H. Hwang Auranofin, as an anti-rheumatic gold compound, suppresses LPS-induced homodimerization of TLR4 Biochem. Biophys. Res. Commun. 350 2006 866 871
27. H.S. Youn, S.I. Saitoh, K. Miyake, and D.H. Hwang Inhibition of homodimerization of Toll-like receptor 4 by curcumin Biochem. Pharmacol. 72 2006 62 69
28. H.S. Youn, J.K. Lee, Y.J. Choi, S.I. Saitoh, K. Miyake, D.H. Hwang, and J.Y. Lee Cinnamaldehyde suppresses toll-like receptor 4 activation mediated through the inhibition of receptor oligomerization Biochem. Pharmacol. 75 2008 494 502
29. H.S. Youn, S.I. Ahn, and B.Y. Lee Guggulsterone suppresses the activation of transcription factor IRF3 induced by TLR3 or TLR4 agonists Int. Immunopharmacol. 9 2009 108 112
30. H.S. Youn, Y.S. Kim, Z.Y. Park, S.Y. Kim, N.Y. Choi, S.M. Joung, J.A. Seo, K.M. Lim, M.K. Kwak, D.H. Hwang, and J.Y. Lee Sulforaphane suppresses oligomerization of TLR4 in a thiol-dependent manner J. Immunol. 184 2009 411 419