Combined effect of tumor necrosis factor (TNF)-α and heat shock protein (HSP)-70 in reducing apoptotic injury in hypoxia: A cell culture study

Neuroscience Letters

Volumn 483, Issue 3, 2010, Pages 162-166

  Goel, Gunjan ^a   Guo, Miao ^b   Ding, Jamie ^c   Dornbos, David ^a   Ali, Ahmer ^a   Shenaq, Mohammed ^a   Guthikonda, Murali ^a   Ding, Yuchuan ^a,b  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c PRINCETON UNIVERSITY   (United States)

Author keywords

Cell culture; Hypoxia; Preconditioning; Pro anti apoptotic protein

Indexed keywords

APOPTOSIS INDUCING FACTOR; HEAT SHOCK PROTEIN 70; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN CELL; CELL CULTURE; EMBRYO; ENZYME PHOSPHORYLATION; HYPOXIA; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY;

ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; APOPTOSIS INDUCING FACTOR; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; CELL HYPOXIA; CELLS, CULTURED; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; EMBRYO, MAMMALIAN; GENE EXPRESSION REGULATION; HSP70 HEAT-SHOCK PROTEINS; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEURONS; NEUROPROTECTIVE AGENTS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77956293597     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.07.069     Document Type: Article

References (42)

1. Brewer G.J., Torricelli J.R., Evege E.K., Price P.J. Optimized survival of hippocampal neurons in B27-supplemented neurobasal, a new serum-free medium combination. J. Neurosci. Res. 1993, 35:567-576.
2. Bruce A.J., Boling W., Kindy M.S., Peschon J., Kraemer P.J., Carpenter M.K., Holtsberg F.W., Mattson M.P. Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors. Nat. Med. 1996, 2:788-794.
3. Cao G., Clark R.S., Pei W., Yin W., Zhang F., Sun F.Y., Graham S.H., Chen J. Translocation of apoptosis-inducing factor in vulnerable neurons after transient cerebral ischemia and in neuronal cultures after oxygen-glucose deprivation. J. Cereb. Blood Flow Metab. 2003, 23:1137-1150.
4. Chan P.H. Mitochondria and neuronal death/survival signaling pathways in cerebral ischemia. Neurochem. Res. 2004, 29:1943-1949.
5. Chen J., Graham S.H., Zhu R.L., Simon R.P. Stress proteins and tolerance to focal cerebral ischemia. J. Cereb. Blood Flow Metab. 1996, 16:566-577.
6. Chen J., Simon R. Ischemic tolerance in the brain. Neurology 1997, 48:306-311.
7. Cheng B., Christakos S., Mattson M.P. Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis. Neuron 1994, 12:139-153.
8. Chu C.T., Levinthal D.J., Kulich S.M., Chalovich E.M., DeFranco D.B. Oxidative neuronal injury. The dark side of ERK1/2. Eur. J. Biochem. 2004, 271:2060-2066.
9. Ding Y.H., Mrizek M., Lai Q., Wu Y., Reyes R., Li J., Davis W.W., Ding Y. Exercise preconditioning reduces brain damage and inhibits TNF-alpha receptor expression after hypoxia/reoxygenation: an in vivo and in vitro study. Curr. Neurovasc. Res. 2006, 3:263-271.
10. Ding Y.H., Young C.N., Luan X., Li J., Rafols J.A., Clark J.C., McAllister J.P., Ding Y. Exercise preconditioning ameliorates inflammatory injury in ischemic rats during reperfusion. Acta Neuropathol. 2005, 109:237-246.
11. Giffard R.G., Yenari M.A. Many mechanisms for hsp70 protection from cerebral ischemia. J. Neurosurg. Anesthesiol. 2004, 16:53-61.
12. Ginis I., Jaiswal R., Klimanis D., Liu J., Greenspon J., Hallenbeck J.M. TNF-alpha-induced tolerance to ischemic injury involves differential control of NF-kappaB transactivation: the role of NF-kappaB association with p300 adaptor. J. Cereb. Blood Flow Metab. 2002, 22:142-152.
13. Ginis I., Schweizer U., Brenner M., Liu J., Azzam N., Spatz M., Hallenbeck J.M. TNF-alpha pretreatment prevents subsequent activation of cultured brain cells with TNF-alpha and hypoxia via ceramide. Am. J. Physiol. 1999, 276:C1171-C1183.
14. Gortz B., Hayer S., Tuerck B., Zwerina J., Smolen J.S., Schett G. Tumour necrosis factor activates the mitogen-activated protein kinases p38alpha and ERK in the synovial membrane in vivo. Arthritis Res. Ther. 2005, 7:R1140-1147.
15. Guo M., Lin V., Davis W., Huang T., Carranza A., Sprague S., Reyes R., Jimenez D., Ding Y. Preischemic induction of TNF-alpha by physical exercise reduces blood-brain barrier dysfunction in stroke. J. Cereb. Blood Flow Metab. 2008, 28:1422-1430.
16. Hamilton K.L., Staib J.L., Phillips T., Hess A., Lennon S.L., Powers S.K. Exercise, antioxidants, and HSP72: protection against myocardial ischemia/reperfusion. Free Radic. Biol. Med. 2003, 34:800-809.
17. He Y., Hua Y., Liu W., Hu H., Keep R.F., Xi G. Effects of cerebral ischemia on neuronal hemoglobin. J. Cereb. Blood Flow Metab. 2009, 29:596-605.
18. Hung T.H., Skepper J.N., Burton G.J. In vitro ischemia-reperfusion injury in term human placenta as a model for oxidative stress in pathological pregnancies. Am. J. Pathol. 2001, 159:1031-1043.
19. Joza N., Susin S.A., Daugas E., Stanford W.L., Cho S.K., Li C.Y., Sasaki T., Elia A.J., Cheng H.Y., Ravagnan L., Ferri K.F., Zamzami N., Wakeham A., Hakem R., Yoshida H., Kong Y.Y., Mak T.W., Zuniga-Pflucker J.C., Kroemer G., Penninger J.M. Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death. Nature 2001, 410:549-554.
20. Kirino T., Tsujita Y., Tamura A. Induced tolerance to ischemia in gerbil hippocampal neurons. J. Cereb. Blood Flow Metab. 1991, 11:299-307.
21. Lecour S., Suleman N., Deuchar G.A., Somers S., Lacerda L., Huisamen B., Opie L.H. Pharmacological preconditioning with tumor necrosis factor-alpha activates signal transducer and activator of transcription-3 at reperfusion without involving classic prosurvival kinases (Akt and extracellular signal-regulated kinase). Circulation 2005, 112:3911-3918.
22. Lee J.E., Yenari M.A., Sun G.H., Xu L., Emond M.R., Cheng D., Steinberg G.K., Giffard R.G. Differential neuroprotection from human heat shock protein 70 overexpression in in vitro and in vivo models of ischemia and ischemia-like conditions. Exp. Neurol. 2001, 170:129-139.
23. Lee S.E., Chung W.J., Kwak H.B., Chung C.H., Kwack K.B., Lee Z.H., Kim H.H. Tumor necrosis factor-alpha supports the survival of osteoclasts through the activation of Akt and ERK. J. Biol. Chem. 2001, 276:49343-49349.
24. Lee S.H., Kim M., Yoon B.W., Kim Y.J., Ma S.J., Roh J.K., Lee J.S., Seo J.S. Targeted hsp70.1 disruption increases infarction volume after focal cerebral ischemia in mice. Stroke 2001, 32:2905-2912.
25. Liebelt B., Papapetrou P., Ali A., Guo M., Ji X., Peng C., Rogers R., Curry A., Jimenez D., Ding Y. Exercise preconditioning reduces neuronal apoptosis in stroke by up-regulating heat shock protein-70 (heat shock protein-72) and extracellular-signal-regulated-kinase 1/2. Neuroscience 2010, 166:1091-1100.
26. Liu J., Ginis I., Spatz M., Hallenbeck J.M. Hypoxic preconditioning protects cultured neurons against hypoxic stress via TNF-alpha and ceramide. Am. J. Physiol. Cell Physiol. 2000, 278:C144-C153.
27. Luo X., Zuo X., Zhou Y., Zhang B., Shi Y., Liu M., Wang K., McMillian D.R., Xiao X. Extracellular heat shock protein 70 inhibits tumour necrosis factor-alpha induced proinflammatory mediator production in fibroblast-like synoviocytes. Arthritis Res. Ther. 2008, 10:R41.
28. Masada T., Hua Y., Xi G., Ennis S.R., Keep R.F. Attenuation of ischemic brain edema and cerebrovascular injury after ischemic preconditioning in the rat. J. Cereb. Blood Flow Metab. 2001, 21:22-33.
29. Matsumori Y., Hong S.M., Aoyama K., Fan Y., Kayama T., Sheldon R.A., Vexler Z.S., Ferriero D.M., Weinstein P.R., Liu J. Hsp70 overexpression sequesters AIF and reduces neonatal hypoxic/ischemic brain injury. J. Cereb. Blood Flow Metab. 2005, 25:899-910.
30. Mori M., Uchida M., Watanabe T., Kirito K., Hatake K., Ozawa K., Komatsu N. Activation of extracellular signal-regulated kinases ERK1 and ERK2 induces Bcl-xL up-regulation via inhibition of caspase activities in erythropoietin signaling. J. Cell. Physiol. 2003, 195:290-297.
31. Nawashiro H., Martin D., Hallenbeck J.M. Inhibition of tumor necrosis factor and amelioration of brain infarction in mice. J. Cereb. Blood Flow Metab. 1997, 17:229-232.
32. Nawashiro H., Tasaki K., Ruetzler C.A., Hallenbeck J.M. TNF-alpha pretreatment induces protective effects against focal cerebral ischemia in mice. J. Cereb. Blood Flow Metab. 1997, 17:483-490.
33. Ohtsuka K., Suzuki T. Roles of molecular chaperones in the nervous system. Brain Res. Bull. 2000, 53:141-146.
34. Ostrakhovitch E.A., Cherian M.G. Inhibition of extracellular signal regulated kinase (ERK) leads to apoptosis inducing factor (AIF) mediated apoptosis in epithelial breast cancer cells: the lack of effect of ERK in p53 mediated copper induced apoptosis. J. Cell. Biochem. 2005, 95:1120-1134.
35. Sawatzky D.A., Willoughby D.A., Colville-Nash P.R., Rossi A.G. The involvement of the apoptosis-modulating proteins ERK 1/2, Bcl-xL and Bax in the resolution of acute inflammation in vivo. Am. J. Pathol. 2006, 168:33-41.
36. Seo H.R., Chung D.Y., Lee Y.J., Lee D.H., Kim J.I., Bae S., Chung H.Y., Lee S.J., Jeoung D., Lee Y.S. Heat shock protein 25 or inducible heat shock protein 70 activates heat shock factor 1: dephosphorylation on serine 307 through inhibition of ERK1/2 phosphorylation. J. Biol. Chem. 2006, 281:17220-17227.
37. Sharony R., Pintucci G., Saunders P.C., Grossi E.A., Baumann F.G., Galloway A.C., Mignatti P. Matrix metalloproteinase expression in vein grafts: role of inflammatory mediators and extracellular signal-regulated kinases-1 and -2. Am. J. Physiol. Heart Circ. Physiol. 2006, 290:H1651-1659.
38. Tsuchiya D., Hong S., Matsumori Y., Shiina H., Kayama T., Swanson R.A., Dillman W.H., Liu J., Panter S.S., Weinstein P.R. Overexpression of rat heat shock protein 70 is associated with reduction of early mitochondrial cytochrome C release and subsequent DNA fragmentation after permanent focal ischemia. J. Cereb. Blood Flow Metab. 2003, 23:718-727.
39. Upcroft J.A., Upcroft P. Drug susceptibility testing of anaerobic protozoa. Antimicrob. Agents Chemother. 2001, 45:1810-1814.
40. Wu C., Fujihara H., Yao J., Qi S., Li H., Shimoji K., Baba H. Different expression patterns of Bcl-2, Bcl-xl, and Bax proteins after sublethal forebrain ischemia in C57Black/Crj6 mouse striatum. Stroke 2003, 34:1803-1808.
41. Yu Z., Liu J., Guo S., Xing C., Fan X., Ning M., Yuan J.C., Lo E.H., Wang X. Neuroglobin-overexpression alters hypoxic response gene expression in primary neuron culture following oxygen glucose deprivation. Neuroscience 2009, 162:396-403.
42. Zhuang S., Schnellmann R.G. A death-promoting role for extracellular signal-regulated kinase. J. Pharmacol. Exp. Ther. 2006, 319:991-997.