메뉴 건너뛰기




Volumn 7, Issue 9, 2010, Pages 3143-3152

Efficacy and Safety of Mirodenafil in Men Taking Antihypertensive Medications

Author keywords

Antihypertensives; Erectile dysfunction; Mirodenafil; PDE5 inhibitor

Indexed keywords

ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; MIRODENAFIL; PHOSPHODIESTERASE V INHIBITOR; PLACEBO; UNCLASSIFIED DRUG;

EID: 77956289068     PISSN: 17436095     EISSN: 17436109     Source Type: Journal    
DOI: 10.1111/j.1743-6109.2010.01926.x     Document Type: Article
Times cited : (17)

References (33)
  • 1
    • 2442476233 scopus 로고    scopus 로고
    • The prevalence of hypertension, hyperlipidemia, diabetes mellitus and depression in men with erectile dysfunction
    • Seftel AD, Sun P, Swindle R. The prevalence of hypertension, hyperlipidemia, diabetes mellitus and depression in men with erectile dysfunction. J Urol 2004, 171:2341-5.
    • (2004) J Urol , vol.171 , pp. 2341-2345
    • Seftel, A.D.1    Sun, P.2    Swindle, R.3
  • 3
    • 84942949401 scopus 로고
    • Impotence. NIH Consensus Development Panel on Impotence
    • NIH Consensus Conference
    • Impotence. NIH Consensus Development Panel on Impotence. JAMA 1993, 270:83-90. NIH Consensus Conference
    • (1993) JAMA , vol.270 , pp. 83-90
  • 5
    • 0028036149 scopus 로고
    • Impotence and its medical and psychosocial correlates: Results of the Massachusetts Male Aging Study
    • Feldman HA, Goldstein I, Hatzichristou DG, Krane RJ, McKinlay JB. Impotence and its medical and psychosocial correlates: Results of the Massachusetts Male Aging Study. J Urol 1994, 151:54-61.
    • (1994) J Urol , vol.151 , pp. 54-61
    • Feldman, H.A.1    Goldstein, I.2    Hatzichristou, D.G.3    Krane, R.J.4    McKinlay, J.B.5
  • 7
    • 0033944586 scopus 로고    scopus 로고
    • Erectile dysfunction in general medicine practice: Prevalence and clinical correlates
    • Chew KK, Earle CM, Stuckey BG, Jamrozik K, Keogh EJ. Erectile dysfunction in general medicine practice: Prevalence and clinical correlates. Int J Impot Res 2000, 12:41-5.
    • (2000) Int J Impot Res , vol.12 , pp. 41-45
    • Chew, K.K.1    Earle, C.M.2    Stuckey, B.G.3    Jamrozik, K.4    Keogh, E.J.5
  • 8
    • 0028837352 scopus 로고
    • Physiology of penile erection
    • Andersson K-E WG. Physiology of penile erection. Physiol Rev 1995, 75:191-236.
    • (1995) Physiol Rev , vol.75 , pp. 191-236
    • Andersson K-E, W.G.1
  • 9
    • 0031456945 scopus 로고    scopus 로고
    • Endothelial dysfunction in essential hypertension
    • Panza JA. Endothelial dysfunction in essential hypertension. Clin Cardiol 1997, 20:26-33.
    • (1997) Clin Cardiol , vol.20 , pp. 26-33
    • Panza, J.A.1
  • 10
    • 0031872742 scopus 로고    scopus 로고
    • Role of nitric oxide in cardiovascular disease: Focus on the endothelium
    • Cannon ROI. Role of nitric oxide in cardiovascular disease: Focus on the endothelium. Clin Chem 1998, 44:1809-19.
    • (1998) Clin Chem , vol.44 , pp. 1809-1819
    • Cannon, R.O.I.1
  • 11
    • 0033663846 scopus 로고    scopus 로고
    • Effect of sildenafil citrate on blood pressure and heart rate in men with erectile dysfunction taking concomitant antihypertensive medication. Sildenafil Study Group
    • Zusman RM, Prisant LM, Brown MJ. Effect of sildenafil citrate on blood pressure and heart rate in men with erectile dysfunction taking concomitant antihypertensive medication. Sildenafil Study Group. J Hypertens 2000, 18:1865-9.
    • (2000) J Hypertens , vol.18 , pp. 1865-1869
    • Zusman, R.M.1    Prisant, L.M.2    Brown, M.J.3
  • 12
    • 0035139921 scopus 로고    scopus 로고
    • Effect of sildenafil in patients with erectile dysfunction taking antihypertensive therapy. Sildenafil Study Group
    • Kloner RA, Brown M, Prisant LM, Collins M. Effect of sildenafil in patients with erectile dysfunction taking antihypertensive therapy. Sildenafil Study Group. Am J Hypertens 2001, 14:70-3.
    • (2001) Am J Hypertens , vol.14 , pp. 70-73
    • Kloner, R.A.1    Brown, M.2    Prisant, L.M.3    Collins, M.4
  • 13
    • 0242460582 scopus 로고    scopus 로고
    • Cardiovascular effects of tadalafil in patients on common antihypertensive therapies
    • Kloner RA, Mitchell M, Emmick JT. Cardiovascular effects of tadalafil in patients on common antihypertensive therapies. Am J Cardiol 2003, 92:47M-57M.
    • (2003) Am J Cardiol , vol.92
    • Kloner, R.A.1    Mitchell, M.2    Emmick, J.T.3
  • 14
    • 28444494448 scopus 로고    scopus 로고
    • Efficacy and safety of vardenafil, a selective phosphodiesterase 5 inhibitor, in men with erectile dysfunction on antihypertensive therapy
    • Porst H, Padma-Nathan H, Thibonnier M, Eardley I. Efficacy and safety of vardenafil, a selective phosphodiesterase 5 inhibitor, in men with erectile dysfunction on antihypertensive therapy. Eur Urol 2002, 152:599.
    • (2002) Eur Urol , vol.152 , pp. 599
    • Porst, H.1    Padma-Nathan, H.2    Thibonnier, M.3    Eardley, I.4
  • 15
    • 28444487883 scopus 로고    scopus 로고
    • Safety and efficacy of vardenafil, a selective phosphodiesterase 5 inhibitor, in patients with erectile dysfunction and arterial hypertension treated with multiple antihypertensives
    • van Ahlen H, Wahle K, Kupper W, Yassin A, Reblin T, Neureither M. Safety and efficacy of vardenafil, a selective phosphodiesterase 5 inhibitor, in patients with erectile dysfunction and arterial hypertension treated with multiple antihypertensives. J Sex Med 2005, 2:856-64.
    • (2005) J Sex Med , vol.2 , pp. 856-864
    • van Ahlen, H.1    Wahle, K.2    Kupper, W.3    Yassin, A.4    Reblin, T.5    Neureither, M.6
  • 16
    • 33845479238 scopus 로고    scopus 로고
    • Synthesis of 5-ethyl-2-{5-[4-(2-hydroxyethyl)piperazin-1-ylsulfonyl]-2-npropoxyphenyl}-7-n-propyl-3,5-dihydro-4H-pyrrolo[3,2-d]-[2-14C]pyrimidin-4-one·2HCl (14CSK3530. 2 HCl)
    • Shin HI, Lee J, Kim DK. Synthesis of 5-ethyl-2-{5-[4-(2-hydroxyethyl)piperazin-1-ylsulfonyl]-2-npropoxyphenyl}-7-n-propyl-3,5-dihydro-4H-pyrrolo[3,2-d]-[2-14C]pyrimidin-4-one·2HCl (14CSK3530. 2 HCl). J Labelled Comp Radiopharm 2006, 49:1141-9.
    • (2006) J Labelled Comp Radiopharm , vol.49 , pp. 1141-1149
    • Shin, H.I.1    Lee, J.2    Kim, D.K.3
  • 17
    • 33947721586 scopus 로고    scopus 로고
    • Metabolism and excretion of 5 ethyl-2-{5-[4-(2-hydroxyethyl) piperazine-1-sulfonyl]-2-propoxyphenyl}-7-propyl-3,5-dihydropyrrolo[3,2-d]-pyrimidin-4-one (SK 3530) in rats
    • Lee J, Yoo HH, Rhim KJ, Sohn DR, Kim DH. Metabolism and excretion of 5 ethyl-2-{5-[4-(2-hydroxyethyl) piperazine-1-sulfonyl]-2-propoxyphenyl}-7-propyl-3,5-dihydropyrrolo[3,2-d]-pyrimidin-4-one (SK 3530) in rats. Rapid Commun Mass Spectrom 2007, 21:1139-49.
    • (2007) Rapid Commun Mass Spectrom , vol.21 , pp. 1139-1149
    • Lee, J.1    Yoo, H.H.2    Rhim, K.J.3    Sohn, D.R.4    Kim, D.H.5
  • 19
    • 0030926566 scopus 로고    scopus 로고
    • The international index of erectile function (IIEF): A multidimensional scale for assessment of erectile dysfunction
    • Rosen RC, Riley A, Wagner G, Osterloh IH, Kirkpatrick J, Mishra A. The international index of erectile function (IIEF): A multidimensional scale for assessment of erectile dysfunction. Urology 1997, 49:822-30.
    • (1997) Urology , vol.49 , pp. 822-830
    • Rosen, R.C.1    Riley, A.2    Wagner, G.3    Osterloh, I.H.4    Kirkpatrick, J.5    Mishra, A.6
  • 21
    • 53549087228 scopus 로고    scopus 로고
    • An open-label, multicenter, flexible dose study to evaluate the efficacy and safety of Viagra (sildenafil citrate) in Korean men with erectile dysfunction and arterial hypertension who are taking antihypertensive agents
    • Park HJ, Park NC, Shim HB, Park JK, Lee SW, Park K, Kim SW, Moon KH, Lee DH, Yoon SJ. An open-label, multicenter, flexible dose study to evaluate the efficacy and safety of Viagra (sildenafil citrate) in Korean men with erectile dysfunction and arterial hypertension who are taking antihypertensive agents. J Sex Med 2008, 5:2405-13.
    • (2008) J Sex Med , vol.5 , pp. 2405-2413
    • Park, H.J.1    Park, N.C.2    Shim, H.B.3    Park, J.K.4    Lee, S.W.5    Park, K.6    Kim, S.W.7    Moon, K.H.8    Lee, D.H.9    Yoon, S.J.10
  • 22
    • 30744463281 scopus 로고    scopus 로고
    • Efficacy of tadalafil in the treatment of erectile dysfunction in hypertensive men on concomitant thiazide diuretic therapy
    • Kloner RA, Sadovsky R, Johnson EG, Mo D, Ahuja S. Efficacy of tadalafil in the treatment of erectile dysfunction in hypertensive men on concomitant thiazide diuretic therapy. Int J Impot Res 2005, 17:450-4.
    • (2005) Int J Impot Res , vol.17 , pp. 450-454
    • Kloner, R.A.1    Sadovsky, R.2    Johnson, E.G.3    Mo, D.4    Ahuja, S.5
  • 23
    • 70649084279 scopus 로고    scopus 로고
    • The efficacy and safety of Udenafil [zydena] for the treatment of erectile dysfunction in hypersensitive men taking concomitant antihypertensive agents
    • Paick JS, Kim SW, Park YK, Hyun JS, Park NC, Lee SW, Park K, Moon KH, Chung WS. The efficacy and safety of Udenafil [zydena] for the treatment of erectile dysfunction in hypersensitive men taking concomitant antihypertensive agents. J Sex Med 2009, 6:3166-76.
    • (2009) J Sex Med , vol.6 , pp. 3166-3176
    • Paick, J.S.1    Kim, S.W.2    Park, Y.K.3    Hyun, J.S.4    Park, N.C.5    Lee, S.W.6    Park, K.7    Moon, K.H.8    Chung, W.S.9
  • 24
    • 0033522244 scopus 로고    scopus 로고
    • Sildenafil citrate and blood-pressure-lowering drugs: Results of drug interaction studies with an organic nitrate and a calcium antagonist
    • Webb DJ, Freestone S, Allen MJ, Muirhead GJ. Sildenafil citrate and blood-pressure-lowering drugs: Results of drug interaction studies with an organic nitrate and a calcium antagonist. Am J Cardiol 1999, 83:21C-8C.
    • (1999) Am J Cardiol , vol.83
    • Webb, D.J.1    Freestone, S.2    Allen, M.J.3    Muirhead, G.J.4
  • 25
    • 0011049813 scopus 로고    scopus 로고
    • Influence of vardenafil on blood pressure and pharmacokinetics in hypertensive patients on nifedipine therapy. [Abstract]
    • Rohde G, Jordaan P. Influence of vardenafil on blood pressure and pharmacokinetics in hypertensive patients on nifedipine therapy. [Abstract]. Pharmacotherapy 2002, 22:418.
    • (2002) Pharmacotherapy , vol.22 , pp. 418
    • Rohde, G.1    Jordaan, P.2
  • 26
    • 0036242933 scopus 로고    scopus 로고
    • Effects of sildenafil citrate (viagra) on blood pressure in normotensive and hypertensive men
    • Vardi Y, Klein L, Nassar S, Sprecher E, Gruenwald I. Effects of sildenafil citrate (viagra) on blood pressure in normotensive and hypertensive men. Urology 2002, 59:747-52.
    • (2002) Urology , vol.59 , pp. 747-752
    • Vardi, Y.1    Klein, L.2    Nassar, S.3    Sprecher, E.4    Gruenwald, I.5
  • 27
    • 33747081117 scopus 로고    scopus 로고
    • Influence of a single dose of 20 mg tadalafil, a phosphodiesterase 5 inhibitor, on ambulatory blood pressure in subjects with hypertension
    • Patterson D, McInnes GT, Webster J, Mitchell MM, Macdonald TM. Influence of a single dose of 20 mg tadalafil, a phosphodiesterase 5 inhibitor, on ambulatory blood pressure in subjects with hypertension. Br J Clin Pharmacol 2006, 62:280-7.
    • (2006) Br J Clin Pharmacol , vol.62 , pp. 280-287
    • Patterson, D.1    McInnes, G.T.2    Webster, J.3    Mitchell, M.M.4    Macdonald, T.M.5
  • 28
    • 0035907009 scopus 로고    scopus 로고
    • Ethanol inhibits L-arginine uptake and enhances NO formation in human placenta
    • Acevedo CG, Carrasco G, Burotto M, Rojas S, Bravo I. Ethanol inhibits L-arginine uptake and enhances NO formation in human placenta. Life Sci 2001, 68:2893-903.
    • (2001) Life Sci , vol.68 , pp. 2893-2903
    • Acevedo, C.G.1    Carrasco, G.2    Burotto, M.3    Rojas, S.4    Bravo, I.5
  • 29
    • 68649115304 scopus 로고    scopus 로고
    • Influence of alcohol on the hemodynamic effects and pharmacokinetic properties of mirodenafil: A single-dose, randomized-sequence, open-label, crossover study in healthy male volunteers in Korea
    • Kim BH, Yi S, Kim J, Lim KS, Kim KP, Lee B, Shin SG, Jang IJ, Yu KS. Influence of alcohol on the hemodynamic effects and pharmacokinetic properties of mirodenafil: A single-dose, randomized-sequence, open-label, crossover study in healthy male volunteers in Korea. Clin Ther 2009, 31:1234-43.
    • (2009) Clin Ther , vol.31 , pp. 1234-1243
    • Kim, B.H.1    Yi, S.2    Kim, J.3    Lim, K.S.4    Kim, K.P.5    Lee, B.6    Shin, S.G.7    Jang, I.J.8    Yu, K.S.9
  • 31
    • 0033044323 scopus 로고    scopus 로고
    • Sexual dysfunction related to antihypertensive agents: Results from the animal model
    • Srilatha B, Adaikan PG, Arulkumaran S, Ng SC. Sexual dysfunction related to antihypertensive agents: Results from the animal model. Int J Impot Res 1999, 11:107-13.
    • (1999) Int J Impot Res , vol.11 , pp. 107-113
    • Srilatha, B.1    Adaikan, P.G.2    Arulkumaran, S.3    Ng, S.C.4
  • 32
    • 1642458256 scopus 로고    scopus 로고
    • Effect of the angiotensin II antagonist valsartan on sexual function in hypertensive men
    • Düsing R. Effect of the angiotensin II antagonist valsartan on sexual function in hypertensive men. Blood Press Suppl 2003, 2:29-34.
    • (2003) Blood Press Suppl , vol.2 , pp. 29-34
    • Düsing, R.1
  • 33
    • 0035142782 scopus 로고    scopus 로고
    • Sexual activity in hypertensive men treated with valsartan or carvedilol: A crossover study
    • Fogari R, Zoppi A, Poletti L, Marasi G, Mugellini A, Corradi L. Sexual activity in hypertensive men treated with valsartan or carvedilol: A crossover study. Am J Hypertens 2001, 14:27-31.
    • (2001) Am J Hypertens , vol.14 , pp. 27-31
    • Fogari, R.1    Zoppi, A.2    Poletti, L.3    Marasi, G.4    Mugellini, A.5    Corradi, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.