Efficacy of tadalafil in the treatment of erectile dysfunction in hypertensive men on concomitant thiazide diuretic therapy

International Journal of Impotence Research

Volumn 17, Issue 5, 2005, Pages 450-454

  Kloner, R A ^a,d   Sadovsky, R ^b   Johnson, E G ^c   Mo, D ^c   Ahuja, S ^c  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b SUNY DOWNSTATE MEDICAL CENTER   (United States)

^c ELI LILLY AND COMPANY   (United States)

^d GOOD SAMARITAN HOSPITAL   (United States)

Author keywords

Erectile dysfunction; Hypertension; Tadalafil; Thiazide diuretics

Indexed keywords

BENDROFLUMETHIAZIDE; CHLOROTHIAZIDE; CHLORTALIDONE; HYDROCHLOROTHIAZIDE; INDAPAMIDE; METOLAZONE; PLACEBO; TADALAFIL; THIAZIDE DIURETIC AGENT; TRICHLORMETHIAZIDE;

ANTIHYPERTENSIVE THERAPY; ARTICLE; BACKACHE; CLINICAL TRIAL; COMORBIDITY; COMPARATIVE STUDY; COUGHING; DIZZINESS; DRUG EFFICACY; DYSPEPSIA; ERECTILE DYSFUNCTION; FLUSHING; HEADACHE; HUMAN; HYPERTENSION; HYPOTENSION; LIMB PAIN; MYALGIA; NOSE CONGESTION; ORTHOSTATIC HYPOTENSION; PRIORITY JOURNAL; QUESTIONNAIRE; RANDOMIZATION; SEXUAL INTERCOURSE; SIDE EFFECT; SYNCOPE; TREATMENT OUTCOME; TREATMENT RESPONSE; UNCONSCIOUSNESS; UPPER RESPIRATORY TRACT INFECTION;

ADULT; AGED; AGED, 80 AND OVER; CARBOLINES; HUMANS; HYPERTENSION; IMPOTENCE; MALE; MIDDLE AGED; SODIUM CHLORIDE SYMPORTER INHIBITORS; TREATMENT OUTCOME;

EID: 30744463281     PISSN: 09559930     EISSN: 14765489     Source Type: Journal    
DOI: 10.1038/sj.ijir.3901360     Document Type: Article

References (10)

1. Chobanian AV et al. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA 2003; 289: 2560-2572.
2. Weiss RJ. Effects of antihypertensive agents on sexual function. Am Fam Physician 1991; 44: 2075-2082.
3. Chang SW et al. The impact of diuretic therapy on reported sexual function. Arch Intern Med 1991; 151: 2402-2408.
4. Grimm Jr RH et al. Long-term effects on sexual function of five antihypertensive drugs and nutritional hygienic treatment in hypertensive men and women. Treatment of Mild Hypertension Study (TOMHS). Hypertension 1997; 29: 8-14.
5. Wassertheil-Smoller S et al. Effect of antihypertensives on sexual function and quality of life: the TAIM Study. Ann Intern Med 1991; 114: 613-620.
6. Keene LC, Davies PH. Drug-related erectile dysfunction. Adverse Drug React Toxicol Rev 1999; 18: 5-24.
7. The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). JAMA 2002; 288: 2981-2997.
8. Cappelleri JC et al. Diagnostic evaluation of the erectile function domain of the International Index of Erectile Function. Urology 1999; 5: 346.
9. Brock GB et al. Efficacy and safety of tadalafil in the treatment of erectile dysfunction: results of integrated analyses. J Urol 2002; 168: 1332-1336.
10. Carson CC et al. The efficacy and safety of tadalafil: an update. Br J Urol Int 2004; 93: 1276-1281.