메뉴 건너뛰기




Volumn 31, Issue 9, 2010, Pages 1642-1649

Pilot study on the effects of dietary conjugated linoleic acid on tumorigenesis and gene expression in PyMT transgenic mice

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CONJUGATED LINOLEIC ACID; FORMALDEHYDE; PARAFFIN; RNA; UVOMORULIN;

EID: 77956285064     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgq148     Document Type: Article
Times cited : (12)

References (51)
  • 1
    • 84909421035 scopus 로고    scopus 로고
    • National Cancer Institute USA
    • National Cancer Institute USA. (2008) National Cancer Institute Factbook. http://www.cancer.gov/cancertopics/types/breast.
    • (2008) National Cancer Institute Factbook
  • 2
    • 33747356530 scopus 로고    scopus 로고
    • Chemoprevention of breast cancer in postmenopausal women
    • Geller,B.A. et al. (2005) Chemoprevention of breast cancer in postmenopausal women. Breast Dis., 24, 79-92.
    • (2005) Breast Dis. , vol.24 , pp. 79-92
    • Geller, B.A.1
  • 3
    • 0028021474 scopus 로고
    • Conjugated linoleic acid. A powerful anticarcinogen from animal fat sources
    • Ip,C. et al. (1994) Conjugated linoleic acid. A powerful anticarcinogen from animal fat sources. Cancer, 74, 1050-1054.
    • (1994) Cancer , vol.74 , pp. 1050-1054
    • Ip, C.1
  • 4
    • 0034964992 scopus 로고    scopus 로고
    • The biologically active isomers of conjugated linoleic acid
    • Pariza,M.W. et al. (2001) The biologically active isomers of conjugated linoleic acid. Prog. Lipid Res., 40, 283-298.
    • (2001) Prog. Lipid Res. , vol.40 , pp. 283-298
    • Pariza, M.W.1
  • 5
    • 0034069602 scopus 로고    scopus 로고
    • Conjugated linoleic acid and disease prevention: a review of current knowledge
    • MacDonald,H.B. (2000) Conjugated linoleic acid and disease prevention: a review of current knowledge. J. Am. Coll. Nutr., 19, 111S-118S.
    • (2000) J. Am. Coll. Nutr. , vol.19
    • MacDonald, H.B.1
  • 6
    • 0021760488 scopus 로고
    • Identification of a diene conjugated component of human lipid as octadeca-9, 11-dienoic acid
    • Iversen,S.A. et al. (1984) Identification of a diene conjugated component of human lipid as octadeca-9,11-dienoic acid. FEBS Lett., 171, 320-324.
    • (1984) FEBS Lett. , vol.171 , pp. 320-324
    • Iversen, S.A.1
  • 7
    • 0017023687 scopus 로고
    • Distribution of isomeric octadecenoic fatty acids in milk fat
    • Parodi,P.W. (1976) Distribution of isomeric octadecenoic fatty acids in milk fat. J. Dairy Sci., 59, 1870-1873.
    • (1976) J. Dairy Sci. , vol.59 , pp. 1870-1873
    • Parodi, P.W.1
  • 8
    • 37149029741 scopus 로고    scopus 로고
    • Conjugated linoleic acid isomers and cancer
    • Kelley,N.S. et al. (2007) Conjugated linoleic acid isomers and cancer. J. Nutr., 137, 2599-2607.
    • (2007) J. Nutr. , vol.137 , pp. 2599-2607
    • Kelley, N.S.1
  • 9
    • 0031408652 scopus 로고    scopus 로고
    • Retention of conjugated linoleic acid in the mammary gland is associated with tumor inhibition during the post-initiation phase of carcinogenesis
    • Ip,C. et al. (1997) Retention of conjugated linoleic acid in the mammary gland is associated with tumor inhibition during the post-initiation phase of carcinogenesis. Carcinogenesis, 18, 755-759.
    • (1997) Carcinogenesis , vol.18 , pp. 755-759
    • Ip, C.1
  • 10
    • 0028221810 scopus 로고
    • Conjugated linoleic acid suppresses mammary carcinogenesis and proliferative activity of the mammary gland in the rat
    • Ip,C. et al. (1994) Conjugated linoleic acid suppresses mammary carcinogenesis and proliferative activity of the mammary gland in the rat. Cancer Res., 54, 1212-1215.
    • (1994) Cancer Res. , vol.54 , pp. 1212-1215
    • Ip, C.1
  • 11
    • 0032720394 scopus 로고    scopus 로고
    • Conjugated linoleic acid-enriched butter fat alters mammary gland morphogenesis and reduces cancer risk in rats
    • Ip,C. et al. (1999) Conjugated linoleic acid-enriched butter fat alters mammary gland morphogenesis and reduces cancer risk in rats. J. Nutr., 129, 2135-2142.
    • (1999) J. Nutr. , vol.129 , pp. 2135-2142
    • Ip, C.1
  • 12
    • 0030889624 scopus 로고    scopus 로고
    • Conjugated linoleic acid suppresses the growth of human breast adenocarcinoma cells in SCID mice
    • Visonneau,S. et al. (1997) Conjugated linoleic acid suppresses the growth of human breast adenocarcinoma cells in SCID mice. Anticancer Res., 17, 969-973.
    • (1997) Anticancer Res. , vol.17 , pp. 969-973
    • Visonneau, S.1
  • 13
    • 8644229499 scopus 로고    scopus 로고
    • An overview of the effect of linoleic and conjugated-linoleic acids on the growth of several human tumor cell lines
    • Maggiora,M. et al. (2004) An overview of the effect of linoleic and conjugated-linoleic acids on the growth of several human tumor cell lines. Int. J. Cancer, 112, 909-919.
    • (2004) Int. J. Cancer , vol.112 , pp. 909-919
    • Maggiora, M.1
  • 14
    • 0242576963 scopus 로고    scopus 로고
    • Conjugated linoleic acid inhibits cell proliferation through a p53-dependent mechanism: effects on the expression of G1-restriction points in breast and colon cancer cells
    • Kemp,M.Q. et al. (2003) Conjugated linoleic acid inhibits cell proliferation through a p53-dependent mechanism: effects on the expression of G1-restriction points in breast and colon cancer cells. J. Nutr., 133, 3670-3677.
    • (2003) J. Nutr. , vol.133 , pp. 3670-3677
    • Kemp, M.Q.1
  • 15
    • 33645003644 scopus 로고    scopus 로고
    • Conjugated linoleic acid induces apoptosis in MDA-MB-231 breast cancer cells through ERK/MAPK signalling and mitochondrial pathway
    • Miglietta,A. et al. (2006) Conjugated linoleic acid induces apoptosis in MDA-MB-231 breast cancer cells through ERK/MAPK signalling and mitochondrial pathway. Cancer Lett., 234, 149-157.
    • (2006) Cancer Lett. , vol.234 , pp. 149-157
    • Miglietta, A.1
  • 16
    • 34047155557 scopus 로고    scopus 로고
    • The t10, c12 isomer of conjugated linoleic acid stimulates mammary tumorigenesis in transgenic mice over-expressing erbB2 in the mammary epithelium
    • Ip,M.M. et al. (2007) The t10, c12 isomer of conjugated linoleic acid stimulates mammary tumorigenesis in transgenic mice over-expressing erbB2 in the mammary epithelium. Carcinogenesis, 28, 1269-1276.
    • (2007) Carcinogenesis , vol.28 , pp. 1269-1276
    • Ip, M.M.1
  • 17
    • 47249098385 scopus 로고    scopus 로고
    • t10, c12-Conjugated linoleic acid stimulates mammary tumor progression in Her2/ErbB2 mice through activation of both proliferative and survival pathways
    • Meng,X. et al. (2008) t10, c12-Conjugated linoleic acid stimulates mammary tumor progression in Her2/ErbB2 mice through activation of both proliferative and survival pathways. Carcinogenesis, 29, 1013-1021.
    • (2008) Carcinogenesis , vol.29 , pp. 1013-1021
    • Meng, X.1
  • 18
    • 34547119309 scopus 로고    scopus 로고
    • Transforming growth factor alpha dependent cancer progression is modulated by Muc1
    • Pochampalli,M.R. et al. (2007) Transforming growth factor alpha dependent cancer progression is modulated by Muc1. Cancer Res., 67, 6591-6598.
    • (2007) Cancer Res. , vol.67 , pp. 6591-6598
    • Pochampalli, M.R.1
  • 19
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipides from animal tissues
    • Folch,J. et al. (1957) A simple method for the isolation and purification of total lipides from animal tissues. J. Biol. Chem., 226, 497-509.
    • (1957) J. Biol. Chem. , vol.226 , pp. 497-509
    • Folch, J.1
  • 20
    • 5644233725 scopus 로고    scopus 로고
    • Effects of specific conjugated linoleic acid isomers on growth characteristics in obese Zucker rats
    • Sanders,S.R. et al. (2004) Effects of specific conjugated linoleic acid isomers on growth characteristics in obese Zucker rats. Lipids, 39, 537-543.
    • (2004) Lipids , vol.39 , pp. 537-543
    • Sanders, S.R.1
  • 21
    • 0142244181 scopus 로고    scopus 로고
    • Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases
    • Lin,E.Y. et al. (2003) Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases. Am. J. Pathol., 163, 2113-2126.
    • (2003) Am. J. Pathol. , vol.163 , pp. 2113-2126
    • Lin, E.Y.1
  • 22
    • 0034696279 scopus 로고    scopus 로고
    • The mammary pathology of genetically engineered mice: the consensus report and recommendations from the Annapolis meeting
    • Cardiff,R.D. et al. (2000) The mammary pathology of genetically engineered mice: the consensus report and recommendations from the Annapolis meeting. Oncogene, 19, 968-988.
    • (2000) Oncogene , vol.19 , pp. 968-988
    • Cardiff, R.D.1
  • 23
    • 0142121516 scopus 로고    scopus 로고
    • Exploration, normalization, and summaries of high density oligonucleotide array probe level data
    • Irizarry,R.A. et al. (2003) Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics, 4, 249-264.
    • (2003) Biostatistics , vol.4 , pp. 249-264
    • Irizarry, R.A.1
  • 24
    • 4344571581 scopus 로고    scopus 로고
    • Rank products: a simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments
    • Breitling,R. et al. (2004) Rank products: a simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments. FEBS Lett., 573, 83-92.
    • (2004) FEBS Lett. , vol.573 , pp. 83-92
    • Breitling, R.1
  • 25
    • 0020519557 scopus 로고
    • Polyoma virus transforming protein associates with the product of the c-src cellular gene
    • Courtneidge,S.A. et al. (1983) Polyoma virus transforming protein associates with the product of the c-src cellular gene. Nature, 303, 435-439.
    • (1983) Nature , vol.303 , pp. 435-439
    • Courtneidge, S.A.1
  • 26
    • 0027954475 scopus 로고
    • Activation of the c-Src tyrosine kinase is required for the induction of mammary tumors in transgenic mice
    • Guy,C.T. et al. (1994) Activation of the c-Src tyrosine kinase is required for the induction of mammary tumors in transgenic mice. Genes Dev., 8, 23-32.
    • (1994) Genes Dev. , vol.8 , pp. 23-32
    • Guy, C.T.1
  • 27
    • 0031948388 scopus 로고    scopus 로고
    • Requirement for both Shc and phosphatidylinositol 3′ kinase signaling pathways in polyomavirus middle T-mediated mammary tumorigenesis
    • Webster,M.A. et al. (1998) Requirement for both Shc and phosphatidylinositol 3′ kinase signaling pathways in polyomavirus middle T-mediated mammary tumorigenesis. Mol. Cell. Biol., 18, 2344-2359.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2344-2359
    • Webster, M.A.1
  • 28
    • 33747360733 scopus 로고    scopus 로고
    • MEKK1 controls matrix degradation and tumor cell dissemination during metastasis of polyoma middle-T driven mammary cancer
    • Cuevas,B.D. et al. (2006) MEKK1 controls matrix degradation and tumor cell dissemination during metastasis of polyoma middle-T driven mammary cancer. Oncogene, 25, 4998-5010.
    • (2006) Oncogene , vol.25 , pp. 4998-5010
    • Cuevas, B.D.1
  • 29
    • 0026649553 scopus 로고
    • Immunohistochemical evaluation of E-cadherin adhesion molecule expression in human gastric cancer
    • Oka,H. et al. (1992) Immunohistochemical evaluation of E-cadherin adhesion molecule expression in human gastric cancer. Virchows Arch. A Pathol. Anat. Histopathol., 421, 149-156.
    • (1992) Virchows Arch. A Pathol. Anat. Histopathol. , vol.421 , pp. 149-156
    • Oka, H.1
  • 30
    • 0030888322 scopus 로고    scopus 로고
    • Co-ordinated changes in expression of cell adhesion molecules in prostate cancer
    • Murant,S.J. et al. (1997) Co-ordinated changes in expression of cell adhesion molecules in prostate cancer. Eur. J. Cancer, 33, 263-271.
    • (1997) Eur. J. Cancer , vol.33 , pp. 263-271
    • Murant, S.J.1
  • 31
    • 0030852218 scopus 로고    scopus 로고
    • Reduced expression of the cadherin-catenin complex in oesophageal adenocarcinoma correlates with poor prognosis
    • Krishnadath,K.K. et al. (1997) Reduced expression of the cadherin-catenin complex in oesophageal adenocarcinoma correlates with poor prognosis. J. Pathol., 182, 331-338.
    • (1997) J. Pathol. , vol.182 , pp. 331-338
    • Krishnadath, K.K.1
  • 32
    • 35349019235 scopus 로고    scopus 로고
    • Cdc42 is crucial for the establishment of epithelial polarity during early mammalian development
    • Wu,X. et al. (2007) Cdc42 is crucial for the establishment of epithelial polarity during early mammalian development. Dev. Dyn., 236, 2767-2778.
    • (2007) Dev. Dyn. , vol.236 , pp. 2767-2778
    • Wu, X.1
  • 33
    • 33644751815 scopus 로고    scopus 로고
    • Cdc42 controls progenitor cell differentiation and betacatenin turnover in skin
    • Wu,X. et al. (2006) Cdc42 controls progenitor cell differentiation and betacatenin turnover in skin. Genes Dev., 20, 571-585.
    • (2006) Genes Dev. , vol.20 , pp. 571-585
    • Wu, X.1
  • 34
    • 34047139914 scopus 로고    scopus 로고
    • Conjugated linoleic acid induces apoptosis of murine mammary tumor cells via Bcl-2 loss
    • Ou,L. et al. (2007) Conjugated linoleic acid induces apoptosis of murine mammary tumor cells via Bcl-2 loss. Biochem. Biophys. Res. Commun., 356, 1044-1049.
    • (2007) Biochem. Biophys. Res. Commun. , vol.356 , pp. 1044-1049
    • Ou, L.1
  • 35
    • 0036682019 scopus 로고    scopus 로고
    • Inhibition of angiogenesis by the cancer chemopreventive agent conjugated linoleic acid
    • Masso-Welch,P.A. et al. (2002) Inhibition of angiogenesis by the cancer chemopreventive agent conjugated linoleic acid. Cancer Res., 62, 4383-4389.
    • (2002) Cancer Res. , vol.62 , pp. 4383-4389
    • Masso-Welch, P.A.1
  • 36
    • 24344450669 scopus 로고    scopus 로고
    • Inhibition of colon cancer cell proliferation by the dietary compound conjugated linoleic acid is mediated by the CDK inhibitor p21CIP1/WAF1
    • Lim,D.Y. et al. (2005) Inhibition of colon cancer cell proliferation by the dietary compound conjugated linoleic acid is mediated by the CDK inhibitor p21CIP1/WAF1. J. Cell. Physiol., 205, 107-113.
    • (2005) J. Cell. Physiol. , vol.205 , pp. 107-113
    • Lim, D.Y.1
  • 37
    • 33750612531 scopus 로고    scopus 로고
    • trans-10, cis-12 conjugated linoleic acid inhibits the G1-S cell cycle progression in DU145 human prostate carcinoma cells
    • Kim,E.J. et al. (2006) trans-10, cis-12 conjugated linoleic acid inhibits the G1-S cell cycle progression in DU145 human prostate carcinoma cells. J. Med. Food, 9, 293-299.
    • (2006) J. Med. Food , vol.9 , pp. 293-299
    • Kim, E.J.1
  • 38
    • 32444444171 scopus 로고    scopus 로고
    • Conjugated linoleic acid attenuates cyclooxygenase-2 transcriptional activity via an anti-AP-1 mechanism in MCF-7 breast cancer cells
    • Degner,S.C. et al. (2006) Conjugated linoleic acid attenuates cyclooxygenase-2 transcriptional activity via an anti-AP-1 mechanism in MCF-7 breast cancer cells. J. Nutr., 136, 421-427.
    • (2006) J. Nutr. , vol.136 , pp. 421-427
    • Degner, S.C.1
  • 39
    • 33646197169 scopus 로고    scopus 로고
    • Conjugated linoleic acid stimulates an antitumorigenic protein NAG-1 in an isomer specific manner
    • Lee,S.H. et al. (2006) Conjugated linoleic acid stimulates an antitumorigenic protein NAG-1 in an isomer specific manner. Carcinogenesis, 27, 972-981.
    • (2006) Carcinogenesis , vol.27 , pp. 972-981
    • Lee, S.H.1
  • 40
    • 0032796505 scopus 로고    scopus 로고
    • Conjugated linoleic acid is a potent naturally occurring ligand and activator of PPARalpha
    • Moya-Camarena,S.Y. et al. (1999) Conjugated linoleic acid is a potent naturally occurring ligand and activator of PPARalpha. J. Lipid Res., 40, 1426-1433.
    • (1999) J. Lipid Res. , vol.40 , pp. 1426-1433
    • Moya-Camarena, S.Y.1
  • 41
    • 27544496982 scopus 로고    scopus 로고
    • Anti-estrogenic effects of conjugated linoleic acid through modulation of estrogen receptor phosphorylation
    • Liu,J. et al. (2005) Anti-estrogenic effects of conjugated linoleic acid through modulation of estrogen receptor phosphorylation. Breast Cancer Res. Treat., 94, 161-169.
    • (2005) Breast Cancer Res. Treat. , vol.94 , pp. 161-169
    • Liu, J.1
  • 42
    • 33645003644 scopus 로고    scopus 로고
    • Conjugated linoleic acid induces apoptosis in MDA-MB-231 breast cancer cells through ERK/MAPK signalling and mitochondrial pathway
    • Miglietta,A. et al. (2006) Conjugated linoleic acid induces apoptosis in MDA-MB-231 breast cancer cells through ERK/MAPK signalling and mitochondrial pathway. Cancer Lett., 234, 149-157.
    • (2006) Cancer Lett. , vol.234 , pp. 149-157
    • Miglietta, A.1
  • 43
    • 0038586230 scopus 로고    scopus 로고
    • Conjugated linoleic acid inhibits cell proliferation and ErbB3 signaling in HT-29 human colon cell line
    • Cho,H.J. et al. (2003) Conjugated linoleic acid inhibits cell proliferation and ErbB3 signaling in HT-29 human colon cell line. Am. J. Physiol. Gastrointest. Liver Physiol., 284, G996-G1005.
    • (2003) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.284
    • Cho, H.J.1
  • 44
    • 0026319061 scopus 로고
    • Mammary cancer prevention by conjugated dienoic derivative of linoleic acid
    • Ip,C. et al. (1991) Mammary cancer prevention by conjugated dienoic derivative of linoleic acid. Cancer Res., 51, 6118-6124.
    • (1991) Cancer Res. , vol.51 , pp. 6118-6124
    • Ip, C.1
  • 45
    • 0142219884 scopus 로고    scopus 로고
    • Shc proteins are strong, independent prognostic markers for both node-negative and node-positive primary breast cancer
    • Davol,P.A. et al. (2003) Shc proteins are strong, independent prognostic markers for both node-negative and node-positive primary breast cancer. Cancer Res., 63, 6772-6783.
    • (2003) Cancer Res. , vol.63 , pp. 6772-6783
    • Davol, P.A.1
  • 46
    • 0030791050 scopus 로고    scopus 로고
    • Effect of conjugated linoleic acid on body composition in mice
    • Park,Y. et al. (1997) Effect of conjugated linoleic acid on body composition in mice. Lipids, 32, 853-858.
    • (1997) Lipids , vol.32 , pp. 853-858
    • Park, Y.1
  • 47
    • 34250376883 scopus 로고    scopus 로고
    • Involvement of PPAR gamma and E-cadherin/betacatenin pathway in the antiproliferative effect of conjugated linoleic acid in MCF-7 cells
    • Bocca,C. et al. (2007) Involvement of PPAR gamma and E-cadherin/betacatenin pathway in the antiproliferative effect of conjugated linoleic acid in MCF-7 cells. Int. J. Cancer, 121, 248-256.
    • (2007) Int. J. Cancer , vol.121 , pp. 248-256
    • Bocca, C.1
  • 48
    • 33947520304 scopus 로고    scopus 로고
    • Total and high-molecular-weight adiponectin in breast cancer: in vitro and in vivo studies
    • Korner,A. et al. (2007) Total and high-molecular-weight adiponectin in breast cancer: in vitro and in vivo studies. J. Clin. Endocrinol. Metab., 92, 1041-1048.
    • (2007) J. Clin. Endocrinol. Metab. , vol.92 , pp. 1041-1048
    • Korner, A.1
  • 49
    • 12144285739 scopus 로고    scopus 로고
    • Adiponectin and breast cancer risk
    • Mantzoros,C. et al. (2004) Adiponectin and breast cancer risk. J. Clin. Endocrinol. Metab., 89, 1102-1107.
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 1102-1107
    • Mantzoros, C.1
  • 50
    • 30344437854 scopus 로고    scopus 로고
    • Caveolin-1 deficiency (-/-) conveys premalignant alterations in mammary epithelia, with abnormal lumen formation, growth factor independence, and cell invasiveness
    • Sotgia,F. et al. (2006) Caveolin-1 deficiency (-/-) conveys premalignant alterations in mammary epithelia, with abnormal lumen formation, growth factor independence, and cell invasiveness. Am. J. Pathol., 168, 292-309.
    • (2006) Am. J. Pathol. , vol.168 , pp. 292-309
    • Sotgia, F.1
  • 51
    • 55849132170 scopus 로고    scopus 로고
    • Dog as model for down-expression of E-cadherin and b-catenin in tubular epithelial cells in renal fibrosis
    • Aresu,L. et al. (2008) Dog as model for down-expression of E-cadherin and b-catenin in tubular epithelial cells in renal fibrosis. Virchows Arch., 453, 617-625.
    • (2008) Virchows Arch. , vol.453 , pp. 617-625
    • Aresu, L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.