Mitochondrial remodeling following fission inhibition by 15d-PGJ2 involves molecular changes in mitochondrial fusion protein OPA1

Biochemical and Biophysical Research Communications

Volumn 399, Issue 4, 2010, Pages 548-554

  Kar, Rekha ^a   Mishra, Nandita ^a   Singha, Prajjal K ^a   Venkatachalam, Manjeri A ^a   Saikumar, Pothana ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

15d PGJ2; Mitochondrial fission; Mitochondrial fusion; Mitofusin; OPA1; Ubiquitination

Indexed keywords

DRP1 PROTEIN; MEMBRANE FUSION PROTEIN; MEMBRANE PROTEIN; MITOCHONDRIAL FUSION PROTEIN OPA1; MITOCHONDRIAL PROTEIN; MITOFUSIN 1; MITOFUSIN 2; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; 15-DEOXYPROSTAGLANDIN J2; APOPTOSIS REGULATORY PROTEIN; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; DEATH ASSOCIATED PROTEIN KINASE; GUANOSINE TRIPHOSPHATASE; MFN1 PROTEIN, MOUSE; MFN2 PROTEIN, MOUSE; OPA1 PROTEIN (GTPASE), MOUSE; PROSTAGLANDIN D2;

ANIMAL CELL; ARTICLE; CELL ELONGATION; CONTROLLED STUDY; INHIBITION KINETICS; MITOCHONDRION; MITOCHONDRION SWELLING; MOLECULAR DYNAMICS; NONHUMAN; PLASTICITY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RAT; RIGIDITY; UBIQUITINATION; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; ENZYMOLOGY; GENETICS; KNOCKOUT MOUSE; METABOLISM; MOUSE;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASES; GTP PHOSPHOHYDROLASES; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MITOCHONDRIAL SWELLING; PROSTAGLANDIN D2; RATS; UBIQUITINATION; DEATH-ASSOCIATED PROTEIN KINASES;

EID: 77956267202     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.07.108     Document Type: Article

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