Rac1 is required for epithelial stem cell function during dermal and oral mucosal wound healing but not for tissue homeostasis in mice

PLoS ONE

Volumn 5, Issue 5, 2010, Pages

  Castilho, Rogerio M ^a,c   Squarize, Cristiane H ^a,c   Leelahavanichkul, Kantima ^a   Zheng, Yi ^b   Bugge, Thomas ^a   Gutkind, J Silvio ^a  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^b UNIVERSITY OF CINCINNATI   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RAC1 PROTEIN; BIOLOGICAL MARKER; CYTOKERATIN 6;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL FUNCTION; CELL MIGRATION; CELL POPULATION; CELL PROLIFERATION; CONTROLLED STUDY; EPITHELIZATION; GENE EXPRESSION; HAIR FOLLICLE; HUMAN; HUMAN CELL; HUMAN TISSUE; KERATINOCYTE; MOUSE; NONHUMAN; ORAL MUCOSAL DISEASE; PROTEIN FUNCTION; SKIN INJURY; STEM CELL; WOUND CLOSURE; WOUND HEALING; ANIMAL; C57BL MOUSE; CELL MOTION; DERMIS; ENZYMOLOGY; EPIDERMIS; EPITHELIUM CELL; GENE SILENCING; GENETICS; HOMEOSTASIS; METABOLISM; MOUTH MUCOSA; PATHOLOGY; REGENERATION; TONGUE;

MUS;

ANIMALS; BIOLOGICAL MARKERS; CELL MOVEMENT; CELL PROLIFERATION; DERMIS; EPIDERMIS; EPITHELIAL CELLS; GENE KNOCKDOWN TECHNIQUES; HOMEOSTASIS; HUMANS; KERATIN-6; KERATINOCYTES; MICE; MICE, INBRED C57BL; MOUTH MUCOSA; RAC1 GTP-BINDING PROTEIN; REGENERATION; STEM CELLS; TONGUE; WOUND HEALING;

EID: 77956260879     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0010503     Document Type: Article

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