-
1
-
-
0036695338
-
The impossible task of developing a new treatment for heart failure
-
M. Packer The impossible task of developing a new treatment for heart failure J Card Fail 8 2002 193 196
-
(2002)
J Card Fail
, vol.8
, pp. 193-196
-
-
Packer, M.1
-
2
-
-
0019191911
-
High efficiency transformation by direct microinjection of DNA into cultured mammalian cells
-
M.R. Capecchi High efficiency transformation by direct microinjection of DNA into cultured mammalian cells Cell 22 1980 479 488
-
(1980)
Cell
, vol.22
, pp. 479-488
-
-
Capecchi, M.R.1
-
3
-
-
2642616518
-
A transmissible retrovirus expressing human hypoxanthine phosphoribosyltransferase (HPRT): Gene transfer into cells obtained from humans deficient in HPRT
-
D.A. Miller, D.J. Jolly, T. Friedmann, and I.M. Verma A transmissible retrovirus expressing human hypoxanthine phosphoribosyltransferase (HPRT): gene transfer into cells obtained from humans deficient in HPRT Proc Natl Acad Sci U S A 80 1983 4709 4713
-
(1983)
Proc Natl Acad Sci U S A
, vol.80
, pp. 4709-4713
-
-
Miller, D.A.1
Jolly, D.J.2
Friedmann, T.3
Verma, I.M.4
-
4
-
-
0021194048
-
Expression of a retrovirus encoding human HPRT in mice
-
A.D. Miller, R.J. Eckner, D.J. Jolly, T. Friedmann, and I.M. Verma Expression of a retrovirus encoding human HPRT in mice Science 225 1984 630 632
-
(1984)
Science
, vol.225
, pp. 630-632
-
-
Miller, A.D.1
Eckner, R.J.2
Jolly, D.J.3
Friedmann, T.4
Verma, I.M.5
-
5
-
-
0025607319
-
Expression of recombinant genes in myocardium in vivo after direct injection of DNA
-
H. Lin, M.S. Parmacek, G. Morle, S. Bolling, and J.M. Leiden Expression of recombinant genes in myocardium in vivo after direct injection of DNA Circulation 82 1990 2217 2221
-
(1990)
Circulation
, vol.82
, pp. 2217-2221
-
-
Lin, H.1
Parmacek, M.S.2
Morle, G.3
Bolling, S.4
Leiden, J.M.5
-
6
-
-
33748155036
-
Angiogenic gene therapy in patients with nonrevascularizable ischemic heart disease: A phase 2 randomized, controlled trial of AdVEGF(121) (AdVEGF121) versus maximum medical treatment
-
D.J. Stewart, J.D. Hilton, and J.M. Arnold Angiogenic gene therapy in patients with nonrevascularizable ischemic heart disease: a phase 2 randomized, controlled trial of AdVEGF(121) (AdVEGF121) versus maximum medical treatment Gene Ther 13 2006 1503 1511
-
(2006)
Gene Ther
, vol.13
, pp. 1503-1511
-
-
Stewart, D.J.1
Hilton, J.D.2
Arnold, J.M.3
-
7
-
-
68549122767
-
Hepatocyte growth factor plays a critical role in the regulation of cytokine production and induction of endothelial progenitor cell mobilization: A pilot gene therapy study in patients with coronary heart disease
-
Z.J. Yang, S.L. Xu, and B. Chen Hepatocyte growth factor plays a critical role in the regulation of cytokine production and induction of endothelial progenitor cell mobilization: a pilot gene therapy study in patients with coronary heart disease Clin Exp Pharmacol Physiol 36 2009 790 796
-
(2009)
Clin Exp Pharmacol Physiol
, vol.36
, pp. 790-796
-
-
Yang, Z.J.1
Xu, S.L.2
Chen, B.3
-
8
-
-
67349287066
-
VEGF gene therapy fails to improve perfusion of ischemic myocardium in patients with advanced coronary disease: Results of the NORTHERN trial
-
D.J. Stewart, M.J. Kutryk, and D. Fitchett VEGF gene therapy fails to improve perfusion of ischemic myocardium in patients with advanced coronary disease: results of the NORTHERN trial Mol Ther 17 2009 1109 1115
-
(2009)
Mol Ther
, vol.17
, pp. 1109-1115
-
-
Stewart, D.J.1
Kutryk, M.J.2
Fitchett, D.3
-
9
-
-
0034988491
-
Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells
-
K.A. Jackson, S.M. Majka, and H. Wang Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells J Clin Invest 107 2001 1395 1402
-
(2001)
J Clin Invest
, vol.107
, pp. 1395-1402
-
-
Jackson, K.A.1
Majka, S.M.2
Wang, H.3
-
10
-
-
0035044085
-
Neovascularization of ischemic myocardium by human bone-marrow derived angioblasts prevents cardiomyocyte apoptosis, reduces remodelling and improves cardiac function
-
A.A. Kocher, M.D. Schuster, and M.J. Szaboles Neovascularization of ischemic myocardium by human bone-marrow derived angioblasts prevents cardiomyocyte apoptosis, reduces remodelling and improves cardiac function Nat Med 7 2001 430 436
-
(2001)
Nat Med
, vol.7
, pp. 430-436
-
-
Kocher, A.A.1
Schuster, M.D.2
Szaboles, M.J.3
-
11
-
-
0035956699
-
Myoblast transplantation for heart failure
-
P. Menasche, A.A. Hagege, and M. Scorsin Myoblast transplantation for heart failure Lancet 357 2001 279 280
-
(2001)
Lancet
, vol.357
, pp. 279-280
-
-
Menasche, P.1
Hagege, A.A.2
Scorsin, M.3
-
12
-
-
0035810240
-
Bone marrow cells regenerate infarcted myocardium
-
D. Orlic, J. Kajstura, and S. Chimenti Bone marrow cells regenerate infarcted myocardium Nature 410 2001 701 705
-
(2001)
Nature
, vol.410
, pp. 701-705
-
-
Orlic, D.1
Kajstura, J.2
Chimenti, S.3
-
13
-
-
0029041775
-
Myocardial regeneration. Transplanting satellite cells into damaged myocardium
-
P.D. Yoon, R.L. Kao, and G.J. Magovern Myocardial regeneration. Transplanting satellite cells into damaged myocardium Tex Heart Inst J 22 1995 119 125
-
(1995)
Tex Heart Inst J
, vol.22
, pp. 119-125
-
-
Yoon, P.D.1
Kao, R.L.2
Magovern, G.J.3
-
14
-
-
2042538384
-
Recruitment of bone-marrow-derived cells by skeletal and cardiac muscle in adult dystrophic mdx mice
-
R.E. Bittner, C. Schöfer, and K. Weipoltshammer Recruitment of bone-marrow-derived cells by skeletal and cardiac muscle in adult dystrophic mdx mice Anat Embryol 199 1999 391 396
-
(1999)
Anat Embryol
, vol.199
, pp. 391-396
-
-
Bittner, R.E.1
Schöfer, C.2
Weipoltshammer, K.3
-
15
-
-
0344672626
-
Autologous transplantation of bone marrow cells improves damaged heart function
-
S. Tomita, R.K. Li, and R.D. Weisel Autologous transplantation of bone marrow cells improves damaged heart function Circulation 100 1999 II247 II256
-
(1999)
Circulation
, vol.100
-
-
Tomita, S.1
Li, R.K.2
Weisel, R.D.3
-
16
-
-
0033678140
-
Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep
-
K.W. Liechty, T.C. MacKenzie, and A.F. Shaaban Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep Nat Med 6 2000 1282 1286
-
(2000)
Nat Med
, vol.6
, pp. 1282-1286
-
-
Liechty, K.W.1
MacKenzie, T.C.2
Shaaban, A.F.3
-
17
-
-
58149169162
-
Cardiogenic differentiation and transdifferentiation of progenitor cells
-
H. Reinecke, E. Minami, W.Z. Zhu, and M.A. Laflamme Cardiogenic differentiation and transdifferentiation of progenitor cells Circ Res 103 2008 1058 1071
-
(2008)
Circ Res
, vol.103
, pp. 1058-1071
-
-
Reinecke, H.1
Minami, E.2
Zhu, W.Z.3
Laflamme, M.A.4
-
18
-
-
68349111684
-
Transplantation of progenitor cells and regeneration of damaged myocardium: More facts or doubts? Insights from experimental and clinical studies
-
M.F. Piepoli Transplantation of progenitor cells and regeneration of damaged myocardium: more facts or doubts? Insights from experimental and clinical studies J Cardiovasc Med 10 2009 624 634
-
(2009)
J Cardiovasc Med
, vol.10
, pp. 624-634
-
-
Piepoli, M.F.1
-
20
-
-
67650718346
-
Intracoronary autologous bone marrow stem cells transfer for patients with acute myocardial infarction: A meta-analysis of randomised controlled trials
-
S.N. Zhang, A.J. Sun, and J.B. Ge Intracoronary autologous bone marrow stem cells transfer for patients with acute myocardial infarction: A meta-analysis of randomised controlled trials Int J Cardiol 136 2009 178 185
-
(2009)
Int J Cardiol
, vol.136
, pp. 178-185
-
-
Zhang, S.N.1
Sun, A.J.2
Ge, J.B.3
-
21
-
-
70349947234
-
Intracoronary infusion of bone marrow-derived mononuclear cells abrogates adverse left ventricular remodelling post-acute myocardial infarction: Insights from the reinfusion of enriched progenitor cells and infarct remodelling in acute myocardial infarction (REPAIR-AMI) trial
-
V. Schächinger, B. Assmus, and S. Erbs Intracoronary infusion of bone marrow-derived mononuclear cells abrogates adverse left ventricular remodelling post-acute myocardial infarction: insights from the reinfusion of enriched progenitor cells and infarct remodelling in acute myocardial infarction (REPAIR-AMI) trial Eur J Heart Fail 11 2009 973 979
-
(2009)
Eur J Heart Fail
, vol.11
, pp. 973-979
-
-
Schächinger, V.1
Assmus, B.2
Erbs, S.3
-
22
-
-
11144356049
-
Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts
-
C.E. Murry, M.H. Soonpaa, H. Reinecke, and H. Schleyer Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts Nature 428 2004 654 668
-
(2004)
Nature
, vol.428
, pp. 654-668
-
-
Murry, C.E.1
Soonpaa, M.H.2
Reinecke, H.3
Schleyer, H.4
-
23
-
-
41149106402
-
The Myoblast Autologous Grafting in Ischemic Cardiomyopathy (MAGIC) trial: First randomized placebo-controlled study of myoblast transplantation
-
P. Menasché, O. Alfieri, and S. Janssens The Myoblast Autologous Grafting in Ischemic Cardiomyopathy (MAGIC) trial: first randomized placebo-controlled study of myoblast transplantation Circulation 117 2008 1189 1200
-
(2008)
Circulation
, vol.117
, pp. 1189-1200
-
-
Menasché, P.1
Alfieri, O.2
Janssens, S.3
-
24
-
-
33847145871
-
Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens
-
R.R. Smith, L. Barile, and H.C. Cho Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens Circulation 115 2007 896 908
-
(2007)
Circulation
, vol.115
, pp. 896-908
-
-
Smith, R.R.1
Barile, L.2
Cho, H.C.3
-
25
-
-
74949120679
-
Intracoronary administration of cardiac progenitor cells alleviates left ventricular dysfunction in rats with a 30-day-old infarction
-
X.L. Tang, G. Rokosh, and S.K. Sanganalmath Intracoronary administration of cardiac progenitor cells alleviates left ventricular dysfunction in rats with a 30-day-old infarction Circulation 121 2010 293 305
-
(2010)
Circulation
, vol.121
, pp. 293-305
-
-
Tang, X.L.1
Rokosh, G.2
Sanganalmath, S.K.3
-
26
-
-
70549103270
-
A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (prochymal) after acute myocardial infarction
-
J.M. Hare, J.H. Traverse, and T.D. Henry A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (prochymal) after acute myocardial infarction J Am Coll Cardiol 54 2009 2277 2286
-
(2009)
J Am Coll Cardiol
, vol.54
, pp. 2277-2286
-
-
Hare, J.M.1
Traverse, J.H.2
Henry, T.D.3
-
27
-
-
75149151470
-
Adipose tissue: A new source for cardiovascular repair
-
R. Madonna, and R. De Caterina Adipose tissue: a new source for cardiovascular repair J Cardiovasc Med 11 2010 71 80
-
(2010)
J Cardiovasc Med
, vol.11
, pp. 71-80
-
-
Madonna, R.1
De Caterina, R.2
-
28
-
-
34347269599
-
Hyaluronan mixed esters of butyric and retinoic Acid drive cardiac and endothelial fate in term placenta human mesenchymal stem cells and enhance cardiac repair in infarcted rat hearts
-
C. Ventura, S. Cantoni, and F. Bianchi Hyaluronan mixed esters of butyric and retinoic Acid drive cardiac and endothelial fate in term placenta human mesenchymal stem cells and enhance cardiac repair in infarcted rat hearts J Biol Chem 282 2007 14243 14252
-
(2007)
J Biol Chem
, vol.282
, pp. 14243-14252
-
-
Ventura, C.1
Cantoni, S.2
Bianchi, F.3
-
29
-
-
48249116367
-
Gene therapy in heart failure
-
L.E. Vinge, P.W. Raake, and W.J. Koch Gene therapy in heart failure Circ Res 102 2008 1458 1470
-
(2008)
Circ Res
, vol.102
, pp. 1458-1470
-
-
Vinge, L.E.1
Raake, P.W.2
Koch, W.J.3
-
30
-
-
56349118816
-
Recirculating cardiac delivery of AAV2/1SERCA2a improves myocardial function in an experimental model of heart failure in large animals
-
M.J. Byrne, J.M. Power, A. Preovolos, J.A. Mariani, R.J. Hajjar, and D.M. Kaye Recirculating cardiac delivery of AAV2/1SERCA2a improves myocardial function in an experimental model of heart failure in large animals Gene Ther 15 2008 1550 1557
-
(2008)
Gene Ther
, vol.15
, pp. 1550-1557
-
-
Byrne, M.J.1
Power, J.M.2
Preovolos, A.3
Mariani, J.A.4
Hajjar, R.J.5
Kaye, D.M.6
-
31
-
-
76649092318
-
Constitutively active phosphatase inhibitor-1 improves cardiac contractility in young mice but is deleterious after catecholaminergic stress and with aging
-
K. Wittköpper, L. Fabritz, and S. Neef Constitutively active phosphatase inhibitor-1 improves cardiac contractility in young mice but is deleterious after catecholaminergic stress and with aging J Clin Invest 120 2010 617 626
-
(2010)
J Clin Invest
, vol.120
, pp. 617-626
-
-
Wittköpper, K.1
Fabritz, L.2
Neef, S.3
-
32
-
-
68049086486
-
Protein kinase C{alpha}, but not PKC{beta} or PKC{gamma}, regulates contractility and heart failure susceptibility: Implications for ruboxistaurin as a novel therapeutic approach
-
Q. Liu, X. Chen, and S.M. Macdonnell Protein kinase C{alpha}, but not PKC{beta} or PKC{gamma}, regulates contractility and heart failure susceptibility: implications for ruboxistaurin as a novel therapeutic approach Circ Res 105 2009 194 200
-
(2009)
Circ Res
, vol.105
, pp. 194-200
-
-
Liu, Q.1
Chen, X.2
MacDonnell, S.M.3
-
33
-
-
62649133817
-
Calcium upregulation by percutaneous administration of gene therapy in cardiac disease (CUPID Trial), a first-in-human phase 1/2 clinical trial
-
B.E. Jaski, M.L. Jessup, and D.M. Mancini Calcium upregulation by percutaneous administration of gene therapy in cardiac disease (CUPID Trial), a first-in-human phase 1/2 clinical trial J Card Fail 15 2009 171 181
-
(2009)
J Card Fail
, vol.15
, pp. 171-181
-
-
Jaski, B.E.1
Jessup, M.L.2
Mancini, D.M.3
-
34
-
-
0141796313
-
Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts
-
A.A. Mangi, N. Noiseux, and D. Kong Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts Nat Med 9 2003 1195 1201
-
(2003)
Nat Med
, vol.9
, pp. 1195-1201
-
-
Mangi, A.A.1
Noiseux, N.2
Kong, D.3
-
35
-
-
20144382339
-
Vascular endothelial growth factor-expressing mesenchymal stem cell transplantation for the treatment of acute myocardial infarction
-
R. Matsumoto, T. Omura, and M. Yoshiyama Vascular endothelial growth factor-expressing mesenchymal stem cell transplantation for the treatment of acute myocardial infarction Arterioscler Thromb Vasc Biol 25 2005 1168 1173
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 1168-1173
-
-
Matsumoto, R.1
Omura, T.2
Yoshiyama, M.3
-
36
-
-
77955886412
-
Lentiviral gene therapy of murine hematopoietic stem cells ameliorates the Pompe disease phenotype
-
N.P. van Til, M. Stok, and F.S. Aerts Kaya Lentiviral gene therapy of murine hematopoietic stem cells ameliorates the Pompe disease phenotype Blood 115 2010 5329 5337
-
(2010)
Blood
, vol.115
, pp. 5329-5337
-
-
Van Til, N.P.1
Stok, M.2
Aerts Kaya, F.S.3
-
37
-
-
58149347238
-
Paracrine mechanisms in adult stem cell signaling and therapy
-
M. Gnecchi, Z. Zhang, A. Ni, and V.J. Dzau Paracrine mechanisms in adult stem cell signaling and therapy Circ Res 103 2008 1204 1219
-
(2008)
Circ Res
, vol.103
, pp. 1204-1219
-
-
Gnecchi, M.1
Zhang, Z.2
Ni, A.3
Dzau, V.J.4
-
38
-
-
67349206322
-
Role of paracrine factors in stem and progenitor cell mediated cardiac repair and tissue fibrosis
-
J.S. Burchfield, and S. Dimmeler Role of paracrine factors in stem and progenitor cell mediated cardiac repair and tissue fibrosis Fibrogenesis Tissue Repair 1 2008 4
-
(2008)
Fibrogenesis Tissue Repair
, vol.1
, pp. 4
-
-
Burchfield, J.S.1
Dimmeler, S.2
-
39
-
-
33646128955
-
Adeno-associated virus-mediated transduction of VEGF165 improves cardiac tissue viability and functional recovery after permanent coronary occlusion in conscious dogs
-
M. Ferrarini, N. Arsic, and F.A. Recchia Adeno-associated virus-mediated transduction of VEGF165 improves cardiac tissue viability and functional recovery after permanent coronary occlusion in conscious dogs Circ Res 98 2006 954 961
-
(2006)
Circ Res
, vol.98
, pp. 954-961
-
-
Ferrarini, M.1
Arsic, N.2
Recchia, F.A.3
-
40
-
-
77952294182
-
Cardiomyocyte VEGFR-1 activation by VEGF-B induces compensatory hypertrophy and preserves cardiac function after myocardial infarction
-
L. Zentilin, U. Puligadda, and V. Lionetti Cardiomyocyte VEGFR-1 activation by VEGF-B induces compensatory hypertrophy and preserves cardiac function after myocardial infarction FASEB J 24 2010 1467 1478
-
(2010)
FASEB J
, vol.24
, pp. 1467-1478
-
-
Zentilin, L.1
Puligadda, U.2
Lionetti, V.3
-
41
-
-
77954214321
-
Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy
-
M. Pepe, M. Mamdani, and L. Zentilin Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy Circ Res 106 2010 1893 1903
-
(2010)
Circ Res
, vol.106
, pp. 1893-1903
-
-
Pepe, M.1
Mamdani, M.2
Zentilin, L.3
-
42
-
-
70149089882
-
Cardiac transplantation in the United States: An analysis of the UNOS registry
-
M.J. Everly Cardiac transplantation in the United States: an analysis of the UNOS registry Clin Transpl 2008 35 43
-
(2008)
Clin Transpl
, pp. 35-43
-
-
Everly, M.J.1
-
43
-
-
68049102296
-
Silencing the myotrophin gene by RNA interference leads to the regression of cardiac hypertrophy
-
S. Gupta, R. Maitra, D. Young, A. Gupta, and S. Sen Silencing the myotrophin gene by RNA interference leads to the regression of cardiac hypertrophy Am J Physiol Heart Circ Physiol 297 2009 H627 H636
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.297
-
-
Gupta, S.1
Maitra, R.2
Young, D.3
Gupta, A.4
Sen, S.5
-
44
-
-
63649117394
-
Long-term cardiac-targeted RNA interference for the treatment of heart failure restores cardiac function and reduces pathological hypertrophy
-
L. Suckau, H. Fechner, and E. Chemaly Long-term cardiac-targeted RNA interference for the treatment of heart failure restores cardiac function and reduces pathological hypertrophy Circulation 119 2009 1241 1252
-
(2009)
Circulation
, vol.119
, pp. 1241-1252
-
-
Suckau, L.1
Fechner, H.2
Chemaly, E.3
-
45
-
-
77954766181
-
Downregulation of microRNA-29 by antisense inhibitors and a PPAR-{gamma} agonist protects against myocardial ischaemia-reperfusion injury
-
Y. Ye, Z. Hu, Y. Lin, C. Zhang, and J.R. Perez-Polo Downregulation of microRNA-29 by antisense inhibitors and a PPAR-{gamma} agonist protects against myocardial ischaemia-reperfusion injury Cardiovasc Res 2010 Mar 13 [Epub ahead of print]
-
(2010)
Cardiovasc Res
-
-
Ye, Y.1
Hu, Z.2
Lin, Y.3
Zhang, C.4
Perez-Polo, J.R.5
-
46
-
-
69249163009
-
Intracoronary injection of in situ forming alginate hydrogel reverses left ventricular remodeling after myocardial infarction in Swine
-
J. Leor, S. Tuvia, and V. Guetta Intracoronary injection of in situ forming alginate hydrogel reverses left ventricular remodeling after myocardial infarction in Swine J Am Coll Cardiol 54 2009 1014 1023
-
(2009)
J Am Coll Cardiol
, vol.54
, pp. 1014-1023
-
-
Leor, J.1
Tuvia, S.2
Guetta, V.3
-
47
-
-
77951238396
-
Hyaluronan mixed esters of butyric and retinoic acid affording myocardial survival and repair without stem cell transplantation
-
V. Lionetti, S. Cantoni, and C. Cavallini Hyaluronan mixed esters of butyric and retinoic acid affording myocardial survival and repair without stem cell transplantation J Biol Chem 285 2010 9949 9961
-
(2010)
J Biol Chem
, vol.285
, pp. 9949-9961
-
-
Lionetti, V.1
Cantoni, S.2
Cavallini, C.3
|