Mefloquine induces oxidative stress and neurodegeneration in primary rat cortical neurons

NeuroToxicology

Volumn 31, Issue 5, 2010, Pages 518-523

  Hood, Jonathan E ^a   Jenkins, Jerry W ^b   Milatovic, Dejan ^c   Rongzhu, Lu ^d   Aschner, Michael ^c  

^a CFD RESEARCH CORPORATION   (United States)

^b HUDSONALPHA INSTITUTE FOR BIOTECHNOLOGY   (United States)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^d JIANGSU UNIVERSITY   (China)

Author keywords

Glutathione; Isoprostane; Mefloquine; Neurodegeneration; Oxidative stress

Indexed keywords

GLUTATHIONE; ISOPROSTANE DERIVATIVE; MEFLOQUINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CELL STRUCTURE; CELL VIABILITY; CONCENTRATION RESPONSE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DENDRITIC SPINE; EMBRYO; ION MONITORING; MASS FRAGMENTOGRAPHY; NERVE CELL CULTURE; NERVE CELL DEGENERATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANALYSIS OF VARIANCE; ANIMALS; ANTIMALARIALS; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; DENDRITIC SPINES; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO, MAMMALIAN; F2-ISOPROSTANES; GLUTATHIONE; L-LACTATE DEHYDROGENASE; MEFLOQUINE; NERVE DEGENERATION; NEURONS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 77956226033     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuro.2010.05.005     Document Type: Article

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