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Volumn 27, Issue 7, 2010, Pages 426-443

Urapidil, a dual-acting antihypertensive agent: Current usage considerations

(1)  Buch, Jan a  

a NONE   (Denmark)

Author keywords

alpha 1 adrenoreceptor antagonists; blood pressure; hypertension

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CAPTOPRIL; DIHYDRALAZINE; ENALAPRILAT; HYDROCHLOROTHIAZIDE; METOPROLOL; NIFEDIPINE; NITROPRUSSIDE SODIUM; PLACEBO; PRAZOSIN; SEROTONIN 1A RECEPTOR; THIAZIDE DIURETIC AGENT; URAPIDIL;

EID: 77956209594     PISSN: 0741238X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12325-010-0039-0     Document Type: Review
Times cited : (40)

References (89)
  • 2
    • 69349103215 scopus 로고    scopus 로고
    • Shattuck Lecture. The hypertension paradox - More uncontrolled disease despite improved therapy
    • 10.1056/NEJMsa0903829 19710486 1:CAS:528:DC%2BD1MXhtVKhtL3I
    • A.V. Chobanian 2009 Shattuck Lecture. The hypertension paradox - more uncontrolled disease despite improved therapy N Engl J Med 361 878 887 10.1056/NEJMsa0903829 19710486 1:CAS:528:DC%2BD1MXhtVKhtL3I
    • (2009) N Engl J Med , vol.361 , pp. 878-887
    • Chobanian, A.V.1
  • 3
    • 9144248446 scopus 로고    scopus 로고
    • Hypertension treatment and control in five European countries, Canada, and the United States
    • 10.1161/01.HYP.0000103630.72812.10 14638619 1:CAS:528: DC%2BD3sXpvVeqtr8%3D
    • K. Wolf-Maier R.S. Cooper H. Kramer 2004 Hypertension treatment and control in five European countries, Canada, and the United States Hypertension 43 10 17 10.1161/01.HYP.0000103630.72812.10 14638619 1:CAS:528: DC%2BD3sXpvVeqtr8%3D
    • (2004) Hypertension , vol.43 , pp. 10-17
    • Wolf-Maier, K.1    Cooper, R.S.2    Kramer, H.3
  • 4
    • 77951124073 scopus 로고    scopus 로고
    • Antihypertensive drug therapy and blood pressure control in men and women: An international perspective
    • 10.1038/jhh.2009.76 1:CAS:528:DC%2BC3cXkvVGjt74%3D
    • M. Thoenes H.R. Neuberger M. Volpe B.V. Khan W. Kirch M. Böhm 2010 Antihypertensive drug therapy and blood pressure control in men and women: an international perspective J Hum Hypertens 24 536 544 10.1038/jhh.2009.76 1:CAS:528:DC%2BC3cXkvVGjt74%3D
    • (2010) J Hum Hypertens , vol.24 , pp. 536-544
    • Thoenes, M.1    Neuberger, H.R.2    Volpe, M.3    Khan, B.V.4    Kirch, W.5    Böhm, M.6
  • 5
    • 33646095234 scopus 로고    scopus 로고
    • WHO MONICA Project. Trends in the prevalence, awareness, treatment and control of hypertension: The WHO MONICA roject
    • 10.1097/00149831-200602000-00004 16449860
    • R.L. Antikainen V.A. Moltchanov C. Chukwuma Sr 2006 WHO MONICA Project. Trends in the prevalence, awareness, treatment and control of hypertension: the WHO MONICA roject Eur J Cardiovasc Prev Rehabil 13 13 29 10.1097/00149831- 200602000-00004 16449860
    • (2006) Eur J Cardiovasc Prev Rehabil , vol.13 , pp. 13-29
    • Antikainen, R.L.1    Moltchanov, V.A.2    Chukwuma Sr., C.3
  • 6
    • 61749091927 scopus 로고    scopus 로고
    • Continued improvement in hypertension management in England: Results from the Health Survey for England 2006
    • 10.1161/HYPERTENSIONAHA.108.125617 19204180 1:CAS:528: DC%2BD1MXhs1CntLc%3D
    • E. Falaschetti M. Chaudhury J. Mindell N. Poulter 2009 Continued improvement in hypertension management in England: results from the Health Survey for England 2006 Hypertension 53 480 486 10.1161/HYPERTENSIONAHA.108. 125617 19204180 1:CAS:528:DC%2BD1MXhs1CntLc%3D
    • (2009) Hypertension , vol.53 , pp. 480-486
    • Falaschetti, E.1    Chaudhury, M.2    Mindell, J.3    Poulter, N.4
  • 7
    • 34547615709 scopus 로고    scopus 로고
    • 2007 Guidelines for the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)
    • 17562668
    • G. Mancia G. De Backer A. Dominiczak 2007 2007 Guidelines for the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC) Eur Heart J 28 1462 1536 17562668
    • (2007) Eur Heart J , vol.28 , pp. 1462-1536
    • Mancia, G.1    De Backer, G.2    Dominiczak, A.3
  • 8
    • 67650082354 scopus 로고    scopus 로고
    • Use of blood pressure lowering drugs in the prevention of cardiovascular disease: Meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies
    • doi: 10.1136/bmj.b1665
    • Law MR, Morris JK, Wald NJ. Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies. BMJ 2009;338:(doi: 10.1136/bmj.b1665).
    • (2009) BMJ , pp. 338
    • Law, M.R.1    Morris, J.K.2    Wald, N.J.3
  • 9
    • 33646862150 scopus 로고    scopus 로고
    • The prevalence of concomitant hypertension and hypercholesterolaemia in the general population
    • D. De Bacquer G. De Backer 2006 The prevalence of concomitant hypertension and hypercholesterolaemia in the general population Int J Hypertens 110 217 223
    • (2006) Int J Hypertens , vol.110 , pp. 217-223
    • De Bacquer, D.1    De Backer, G.2
  • 10
    • 77950177443 scopus 로고    scopus 로고
    • Blood pressure lowering efficacy of alpha blockers for primary hypertension
    • 19821331
    • B.S. Heran B.P. Galm J.M. Wright 2009 Blood pressure lowering efficacy of alpha blockers for primary hypertension Cochrane Database Syst Rev 4 CD004643 19821331
    • (2009) Cochrane Database Syst Rev , vol.4 , pp. 004643
    • Heran, B.S.1    Galm, B.P.2    Wright, J.M.3
  • 11
    • 0033983621 scopus 로고    scopus 로고
    • The role of alpha 1-blockers in combination therapy for hypertension
    • 10750258 1:CAS:528:DC%2BD3cXhsVeiu7Y%3D
    • R.M. Zusman 2000 The role of alpha 1-blockers in combination therapy for hypertension Int J Clin Pract 54 36 40 10750258 1:CAS:528:DC%2BD3cXhsVeiu7Y%3D
    • (2000) Int J Clin Pract , vol.54 , pp. 36-40
    • Zusman, R.M.1
  • 12
    • 0025690689 scopus 로고
    • Pharmacological profile of antihypertensive drugs with serotonin receptor and alpha-adrenoceptor activity
    • 10.2165/00003495-199000404-00003 1982649
    • P.A. van Zwieten G.J. Blauw P. van Brummelen 1990 Pharmacological profile of antihypertensive drugs with serotonin receptor and alpha-adrenoceptor activity Drugs 40 suppl.4 1 8 10.2165/00003495-199000404-00003 1982649
    • (1990) Drugs , vol.40 , Issue.SUPPL. 4 , pp. 1-8
    • Van Zwieten, P.A.1    Blauw, G.J.2    Van Brummelen, P.3
  • 13
    • 0031728965 scopus 로고    scopus 로고
    • Urapidil. A reappraisal of its use in the management of hypertension
    • 10.2165/00003495-199856050-00016 9829161 1:CAS:528:DyaK1cXns12rsbs%3D
    • M. Dooley K.L. Goa 1998 Urapidil. A reappraisal of its use in the management of hypertension Drugs 56 929 955 10.2165/00003495-199856050-00016 9829161 1:CAS:528:DyaK1cXns12rsbs%3D
    • (1998) Drugs , vol.56 , pp. 929-955
    • Dooley, M.1    Goa, K.L.2
  • 14
    • 0028869120 scopus 로고
    • Addition of urapidil or metoprolol to the treatment of hypertensive non-responders to nifedipine monotherapy: Efficacy and metabolic effects. Italian Urapidil Study Group
    • 8535541 1:STN:280:DyaK287is1Knsg%3D%3D
    • A. Zanchetti 1995 Addition of urapidil or metoprolol to the treatment of hypertensive non-responders to nifedipine monotherapy: efficacy and metabolic effects. Italian Urapidil Study Group Blood Press Suppl 3 38 46 8535541 1:STN:280:DyaK287is1Knsg%3D%3D
    • (1995) Blood Press Suppl , vol.3 , pp. 38-46
    • Zanchetti, A.1
  • 15
    • 0025768857 scopus 로고
    • Antihypertensive effectiveness of urapidil alone and in combination with nifedipine in mild to moderate essential hypertension
    • K. Mizuno S. Fukuchi 1991 Antihypertensive effectiveness of urapidil alone and in combination with nifedipine in mild to moderate essential hypertension Curr Ther Res 50 274 281
    • (1991) Curr Ther Res , vol.50 , pp. 274-281
    • Mizuno, K.1    Fukuchi, S.2
  • 16
    • 0025636467 scopus 로고
    • Antihypertensive efficacy of urapidil versus hydrochlorothiazide alone in patients with mild to moderate essential hypertension and of their combination in nonresponders to monotherapy
    • 10.2165/00003495-199000404-00017 2092970
    • R. Fariello C. Dal Palu A. Pessina 1990 Antihypertensive efficacy of urapidil versus hydrochlorothiazide alone in patients with mild to moderate essential hypertension and of their combination in nonresponders to monotherapy Drugs 40 suppl.4 60 62 10.2165/00003495-199000404-00017 2092970
    • (1990) Drugs , vol.40 , Issue.SUPPL. 4 , pp. 60-62
    • Fariello, R.1    Dal Palu, C.2    Pessina, A.3
  • 17
    • 17944394173 scopus 로고
    • Double-blind comparison of urapidil and prazosin in the treatment of patients with essential hypertension
    • 10.2165/00003495-198800356-00021 3042355
    • Y. Kaneko 1988 Double-blind comparison of urapidil and prazosin in the treatment of patients with essential hypertension Drugs 35 suppl.6 156 163 10.2165/00003495-198800356-00021 3042355
    • (1988) Drugs , vol.35 , Issue.SUPPL. 6 , pp. 156-163
    • Kaneko, Y.1
  • 18
    • 0024274464 scopus 로고
    • Urapidil in patients with severe hypertension and in long-term treatment
    • 2906699 1:STN:280:DyaL1M7lslWnsw%3D%3D
    • T. Takeda Y. Kaneko H. Shionoiri 1988 Urapidil in patients with severe hypertension and in long-term treatment J Hypertens Suppl 6 S37 42 2906699 1:STN:280:DyaL1M7lslWnsw%3D%3D
    • (1988) J Hypertens Suppl , vol.6 , pp. 37-42
    • Takeda, T.1    Kaneko, Y.2    Shionoiri, H.3
  • 19
    • 29244436688 scopus 로고    scopus 로고
    • New-onset diabetes and antihypertensive drugs
    • 10.1097/01.hjh.0000194119.42722.21 16331092 1:CAS:528:DC%2BD2MXht1yitLzE
    • G. Mancia G. Grassi A. Zanchetti 2006 New-onset diabetes and antihypertensive drugs J Hypertens 24 3 10 10.1097/01.hjh.0000194119.42722.21 16331092 1:CAS:528:DC%2BD2MXht1yitLzE
    • (2006) J Hypertens , vol.24 , pp. 3-10
    • Mancia, G.1    Grassi, G.2    Zanchetti, A.3
  • 20
    • 33846294746 scopus 로고    scopus 로고
    • Incident diabetes in clinical trials of antihypertensive drugs: A network metaanalysis
    • 10.1016/S0140-6736(07)60108-1 17240286 1:CAS:528:DC%2BD2sXntlCnsA%3D%3D
    • W.J. Elliott P.M. Meyer 2007 Incident diabetes in clinical trials of antihypertensive drugs: a network metaanalysis Lancet 369 201 207 10.1016/S0140-6736(07)60108-1 17240286 1:CAS:528:DC%2BD2sXntlCnsA%3D%3D
    • (2007) Lancet , vol.369 , pp. 201-207
    • Elliott, W.J.1    Meyer, P.M.2
  • 21
    • 0026780402 scopus 로고
    • Influence of a new multifactorial antihypertensive on blood pressure and metabolic profile in essential hypertension associated with non-insulin- dependent diabetes mellitus
    • R. Fariello E. Boni L. Corda A. Zaninelli A. Noseda A. Spinazzi 1992 Influence of a new multifactorial antihypertensive on blood pressure and metabolic profile in essential hypertension associated with non-insulin- dependent diabetes mellitus Eur Heart J 13suppl.A 65 69
    • (1992) Eur Heart J , vol.13 , pp. 65-69
    • Fariello, R.1    Boni, E.2    Corda, L.3    Zaninelli, A.4    Noseda, A.5    Spinazzi, A.6
  • 22
    • 0029985408 scopus 로고    scopus 로고
    • Efficacy and tolerability of slow release urapidil (ebrantil) in hypertensive patients with non-insulin dependent diabetes mellitus (NIDDM)
    • 8867567 1:STN:280:DyaK2s%2FitFajtQ%3D%3D
    • S. Oren S. Turkot E. Paran O. Flandra L. Slezak B. Hof 1996 Efficacy and tolerability of slow release urapidil (ebrantil) in hypertensive patients with non-insulin dependent diabetes mellitus (NIDDM) J Hum Hypertens 10 123 127 8867567 1:STN:280:DyaK2s%2FitFajtQ%3D%3D
    • (1996) J Hum Hypertens , vol.10 , pp. 123-127
    • Oren, S.1    Turkot, S.2    Paran, E.3    Flandra, O.4    Slezak, L.5    Hof, B.6
  • 23
    • 0026625728 scopus 로고
    • Effects of sustained-release urapidil on essential hypertension and hyperlipidaemia: A multicenter clinical trial
    • Y. Goto 1992 Effects of sustained-release urapidil on essential hypertension and hyperlipidaemia: a multicenter clinical trial Curr Ther Res 51 870 876
    • (1992) Curr Ther Res , vol.51 , pp. 870-876
    • Goto, Y.1
  • 25
    • 77956197722 scopus 로고
    • Effect of urapidil treatment on lipid metabolism in patients with hypertension
    • J.W. Pattenier F.C. von Heusinger 1992 Effect of urapidil treatment on lipid metabolism in patients with hypertension Royal Soc Med Int Congr Symp 196 61 67
    • (1992) Royal Soc Med Int Congr Symp , vol.196 , pp. 61-67
    • Pattenier, J.W.1    Von Heusinger, F.C.2
  • 26
    • 0022392373 scopus 로고
    • Cardiovascular and metabolic profile during intervention with urapidil in humans
    • 3908316 1:STN:280:DyaL28%2FosVegug%3D%3D
    • A. Gerber P. Weidmann C. Marone D. Uehlinger W. Riesen 1985 Cardiovascular and metabolic profile during intervention with urapidil in humans Hypertension 7 963 971 3908316 1:STN:280:DyaL28%2FosVegug%3D%3D
    • (1985) Hypertension , vol.7 , pp. 963-971
    • Gerber, A.1    Weidmann, P.2    Marone, C.3    Uehlinger, D.4    Riesen, W.5
  • 27
    • 77956199792 scopus 로고
    • Effects of long-term antihypertensive therapy with Urapidil (EbrantilR) on lipometabolism
    • K. Held P. Cremer E. Hundertmark D. Seidel 1985 Effects of long-term antihypertensive therapy with Urapidil (EbrantilR) on lipometabolism Hochdruck 5 2
    • (1985) Hochdruck , vol.5 , pp. 2
    • Held, K.1    Cremer, P.2    Hundertmark, E.3    Seidel, D.4
  • 28
    • 0024283739 scopus 로고
    • Metabolically neutral therapy of hypertension. An open, multicenter, prospective long-term study of the tolerance, safety and effectiveness of urapidil
    • 3148534 1:STN:280:DyaL1M7nt1Gquw%3D%3D
    • H. Liebau W. Wurst I. Harder P. Solleder 1988 Metabolically neutral therapy of hypertension. An open, multicenter, prospective long-term study of the tolerance, safety and effectiveness of urapidil Fortschr Med 106 651 654 3148534 1:STN:280:DyaL1M7nt1Gquw%3D%3D
    • (1988) Fortschr Med , vol.106 , pp. 651-654
    • Liebau, H.1    Wurst, W.2    Harder, I.3    Solleder, P.4
  • 29
    • 0029816562 scopus 로고    scopus 로고
    • Urapidil treatment decreases plasma fibrinogen concentration in essential hypertension
    • 10.1016/S0026-0495(96)90239-5 8843176 1:CAS:528:DyaK28XmtFGitrk%3D
    • A. Haenni H. Lithell 1996 Urapidil treatment decreases plasma fibrinogen concentration in essential hypertension Metabolism 45 1221 1229 10.1016/S0026-0495(96)90239-5 8843176 1:CAS:528:DyaK28XmtFGitrk%3D
    • (1996) Metabolism , vol.45 , pp. 1221-1229
    • Haenni, A.1    Lithell, H.2
  • 30
    • 0027153282 scopus 로고
    • Fibrinogen as a cardiovascular risk factor: A meta-analysis and review of the literature
    • 8489110 1:STN:280:DyaK3s3ls1ertQ%3D%3D
    • E. Ernst K.L. Resch 1993 Fibrinogen as a cardiovascular risk factor: a meta-analysis and review of the literature Ann Intern Med 118 956 963 8489110 1:STN:280:DyaK3s3ls1ertQ%3D%3D
    • (1993) Ann Intern Med , vol.118 , pp. 956-963
    • Ernst, E.1    Resch, K.L.2
  • 31
    • 84926426742 scopus 로고    scopus 로고
    • Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: An individual participant meta-analysis
    • 10.1001/jama.294.14.1799 16219884 1:CAS:528:DC%2BD2MXhtFWgsLnM
    • J. Danesh S. Lewington S.G. Thompson 2005 Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis JAMA 294 1799 1809 10.1001/jama.294.14.1799 16219884 1:CAS:528:DC%2BD2MXhtFWgsLnM
    • (2005) JAMA , vol.294 , pp. 1799-1809
    • Danesh, J.1    Lewington, S.2    Thompson, S.G.3
  • 32
    • 0025073827 scopus 로고
    • Acute effect of urapidil on peripheral serotonin metabolism
    • 2225876 1:STN:280:DyaK3M%2FjtVKiuw%3D%3D
    • K. Sebekova V. Fedelesova P. Blazicek R. Dzurik 1990 Acute effect of urapidil on peripheral serotonin metabolism Cor Vasa 32 274 281 2225876 1:STN:280:DyaK3M%2FjtVKiuw%3D%3D
    • (1990) Cor Vasa , vol.32 , pp. 274-281
    • Sebekova, K.1    Fedelesova, V.2    Blazicek, P.3    Dzurik, R.4
  • 33
    • 0025683212 scopus 로고
    • Platelet in vitro responses to urapidil and prazosin
    • 10.2165/00003495-199000404-00013 2092966 1:CAS:528:DyaK3MXkt1Wqsr8%3D
    • C.C. Smith D.J. Betteridge B.N. Prichard 1990 Platelet in vitro responses to urapidil and prazosin Drugs 40 suppl.4 48 51 10.2165/00003495-199000404- 00013 2092966 1:CAS:528:DyaK3MXkt1Wqsr8%3D
    • (1990) Drugs , vol.40 , Issue.SUPPL. 4 , pp. 48-51
    • Smith, C.C.1    Betteridge, D.J.2    Prichard, B.N.3
  • 34
    • 0025006871 scopus 로고
    • Effects of urapidil on 5-hydroxytryptamine induced platelet aggregation and on 14C-5-hydroxytryptamine uptake in platelets
    • 2387654 1:CAS:528:DyaK3cXls1Giu70%3D
    • J. Storck J.G. Ochs R. Kirsten 1990 Effects of urapidil on 5-hydroxytryptamine induced platelet aggregation and on 14C-5-hydroxytryptamine uptake in platelets Int J Clin Pharmacol Ther Toxicol 28 303 308 2387654 1:CAS:528:DyaK3cXls1Giu70%3D
    • (1990) Int J Clin Pharmacol Ther Toxicol , vol.28 , pp. 303-308
    • Storck, J.1    Ochs, J.G.2    Kirsten, R.3
  • 35
    • 0027537885 scopus 로고
    • Effect on urapidil on benign prostatic hypertrophy: A multicenter, double-blind study
    • 10.1159/000282443 7679532 1:STN:280:DyaK3s7ms1Gqug%3D%3D
    • K. Kawabe S. Tsuchida J. Shimazaki T. Morita K. Yasuda S. Kageyama 1993 Effect on urapidil on benign prostatic hypertrophy: a multicenter, double-blind study Urol Int 50 27 32 10.1159/000282443 7679532 1:STN:280:DyaK3s7ms1Gqug%3D%3D
    • (1993) Urol Int , vol.50 , pp. 27-32
    • Kawabe, K.1    Tsuchida, S.2    Shimazaki, J.3    Morita, T.4    Yasuda, K.5    Kageyama, S.6
  • 36
    • 0029776050 scopus 로고    scopus 로고
    • The effect of urapidil on neurogenic bladder: A placebo controlled double-blind study
    • 10.1016/S0022-5347(01)65723-9 8709324 1:CAS:528:DyaK28Xltlahsrc%3D
    • K. Yasuda T. Yamanishi K. Kawabe H. Ohshima T. Morita 1996 The effect of urapidil on neurogenic bladder: a placebo controlled double-blind study J Urol 156 1125 1130 10.1016/S0022-5347(01)65723-9 8709324 1:CAS:528:DyaK28Xltlahsrc%3D
    • (1996) J Urol , vol.156 , pp. 1125-1130
    • Yasuda, K.1    Yamanishi, T.2    Kawabe, K.3    Ohshima, H.4    Morita, T.5
  • 37
    • 0033039037 scopus 로고    scopus 로고
    • A multicenter placebo-controlled, double-blind trial of urapidil, an alpha-blocker, on neurogenic bladder dysfunction
    • 10.1159/000019818 9933794 1:CAS:528:DyaK1MXhvVSitLY%3D
    • T. Yamanishi K. Yasuda Y. Homma K. Kawabe T. Morita 1999 A multicenter placebo-controlled, double-blind trial of urapidil, an alpha-blocker, on neurogenic bladder dysfunction Eur Urol 35 45 51 10.1159/000019818 9933794 1:CAS:528:DyaK1MXhvVSitLY%3D
    • (1999) Eur Urol , vol.35 , pp. 45-51
    • Yamanishi, T.1    Yasuda, K.2    Homma, Y.3    Kawabe, K.4    Morita, T.5
  • 38
    • 1442326127 scopus 로고    scopus 로고
    • Combination of a cholinergic drug and an alpha-blocker is more effective than monotherapy for the treatment of voiding difficulty in patients with underactive detrusor
    • 10.1111/j.1442-2042.2004.00753.x 14706012 1:CAS:528:DC%2BD2cXislalsLw%3D
    • T. Yamanishi K. Yasuda T. Kamai 2004 Combination of a cholinergic drug and an alpha-blocker is more effective than monotherapy for the treatment of voiding difficulty in patients with underactive detrusor Int J Urol 11 88 96 10.1111/j.1442-2042.2004.00753.x 14706012 1:CAS:528:DC%2BD2cXislalsLw%3D
    • (2004) Int J Urol , vol.11 , pp. 88-96
    • Yamanishi, T.1    Yasuda, K.2    Kamai, T.3
  • 39
    • 7844225375 scopus 로고
    • Clinical evaluation of urapidil in hypertensive patients with renal failure
    • Y. Ikeda N. Takagi K. Takeda 1992 Clinical evaluation of urapidil in hypertensive patients with renal failure Shinyaku to Rinsho 41 622 631
    • (1992) Shinyaku to Rinsho , vol.41 , pp. 622-631
    • Ikeda, Y.1    Takagi, N.2    Takeda, K.3
  • 40
    • 0023721064 scopus 로고
    • Renal haemodynamic and neurohumoral responses to urapidil in hypertensive man
    • 10.2165/00003495-198800356-00010 2900132
    • P.W. de Leeuw P.N. van Es H.A. de Bruyn W.H. Birkenhäger 1988 Renal haemodynamic and neurohumoral responses to urapidil in hypertensive man Drugs 35 suppl.6 74 77 10.2165/00003495-198800356-00010 2900132
    • (1988) Drugs , vol.35 , Issue.SUPPL. 6 , pp. 74-77
    • De Leeuw, P.W.1    Van Es, P.N.2    De Bruyn, H.A.3    Birkenhäger, W.H.4
  • 41
    • 0033941525 scopus 로고    scopus 로고
    • Renal haemodynamics and sodium excretory capacity during urapidil treatment in patients with essential hypertension
    • 10.1097/00004872-200018070-00019 10930195 1:CAS:528:DC%2BD3cXlsFGmtr8%3D
    • A.T. Lavrijssen A.A. Kroon M. Fuss-Lejeune P.M. Schiffers P.W. de Leeuw 2000 Renal haemodynamics and sodium excretory capacity during urapidil treatment in patients with essential hypertension J Hypertens 18 963 969 10.1097/00004872-200018070-00019 10930195 1:CAS:528:DC%2BD3cXlsFGmtr8%3D
    • (2000) J Hypertens , vol.18 , pp. 963-969
    • Lavrijssen, A.T.1    Kroon, A.A.2    Fuss-Lejeune, M.3    Schiffers, P.M.4    De Leeuw, P.W.5
  • 42
    • 0024283739 scopus 로고
    • Metabolically neutral therapy of hypertension. An open, multicenter, prospective long-term study of the tolerance, safety and effectiveness of urapidil
    • 3148534 1:STN:280:DyaL1M7nt1Gquw%3D%3D
    • H. Liebau W. Wurst I. Harder P. Solleder 1988 Metabolically neutral therapy of hypertension. An open, multicenter, prospective long-term study of the tolerance, safety and effectiveness of urapidil Fortschr Med 106 651 654 3148534 1:STN:280:DyaL1M7nt1Gquw%3D%3D
    • (1988) Fortschr Med , vol.106 , pp. 651-654
    • Liebau, H.1    Wurst, W.2    Harder, I.3    Solleder, P.4
  • 43
    • 0025716538 scopus 로고
    • Long-term antihypertensive therapy with urapidil. A 3-year open, multicenter trial of tolerance, safety and effectiveness
    • 2118878 1:STN:280:DyaK3cznsFWmtA%3D%3D
    • H. Liebau P. Solleder I. Harder W. Wurst 1990 Long-term antihypertensive therapy with urapidil. A 3-year open, multicenter trial of tolerance, safety and effectiveness Fortschr Med 108 325 328 2118878 1:STN:280:DyaK3cznsFWmtA%3D%3D
    • (1990) Fortschr Med , vol.108 , pp. 325-328
    • Liebau, H.1    Solleder, P.2    Harder, I.3    Wurst, W.4
  • 44
    • 0021932229 scopus 로고
    • Treatment of primary and secondary hypertension. Long-term use of urapidil (Ebrantil®)
    • R. Haerlin 1985 Treatment of primary and secondary hypertension. Long-term use of urapidil (Ebrantil®) Clinical Trials J 22 215 225
    • (1985) Clinical Trials J , vol.22 , pp. 215-225
    • Haerlin, R.1
  • 45
    • 0036460172 scopus 로고    scopus 로고
    • Management of patients with hypertensive urgencies and emergencies: A systematic review of the literature
    • 10.1046/j.1525-1497.2002.20389.x 12472930
    • D. Cherney S. Straus 2002 Management of patients with hypertensive urgencies and emergencies: a systematic review of the literature J Gen Intern Med 17 937 945 10.1046/j.1525-1497.2002.20389.x 12472930
    • (2002) J Gen Intern Med , vol.17 , pp. 937-945
    • Cherney, D.1    Straus, S.2
  • 46
    • 44949243115 scopus 로고    scopus 로고
    • Pharmacological interventions for hypertensive emergencies
    • 18254026
    • M.I. Perez V.M. Musini 2008 Pharmacological interventions for hypertensive emergencies Cochrane Database Syst Rev 1 CD003653 18254026
    • (2008) Cochrane Database Syst Rev , vol.1 , pp. 003653
    • Perez, M.I.1    Musini, V.M.2
  • 48
    • 84868364988 scopus 로고    scopus 로고
    • Agence Française de Sécurité Sanitaire Des Produits de Santé (AFSSAPS). Poussees hypertensives de l'adulte: elevation tensionnelle sans souffrance viscerale immediate et urgences hypertensives [in French]. Agence Française de Sécurité Sanitaire Des Produits de Santé, Saint Denis, France, May 2002. Available at
    • Agence Française de Sécurité Sanitaire Des Produits de Santé (AFSSAPS). Poussees hypertensives de l'adulte: elevation tensionnelle sans souffrance viscerale immediate et urgences hypertensives [in French]. Agence Française de Sécurité Sanitaire Des Produits de Santé, Saint Denis, France, May 2002. Available at
  • 49
    • 33947409549 scopus 로고    scopus 로고
    • Klassifikation, Diagnostik und Therapie der Hypertonie 2007 - Empfehlungen der Österreichischen Gesellschaft für Hypertensiologie
    • J. Slany D. Magometschnigg G. Mayer 2007 Klassifikation, Diagnostik und Therapie der Hypertonie 2007 - Empfehlungen der Österreichischen Gesellschaft für Hypertensiologie J Hypertonie 11 7 11
    • (2007) J Hypertonie , vol.11 , pp. 7-11
    • Slany, J.1    Magometschnigg, D.2    Mayer, G.3
  • 50
    • 0021235805 scopus 로고
    • Therapy of the hypertensive crisis with urapidil. Various effects on patients with or without coronary disease
    • 6469170
    • J. Zähringer M. Klepzig J. Greif B. Ludwig B. Strauer 1984 Therapy of the hypertensive crisis with urapidil. Various effects on patients with or without coronary disease Fortschr Med 102 624 628 6469170
    • (1984) Fortschr Med , vol.102 , pp. 624-628
    • Zähringer, J.1    Klepzig, M.2    Greif, J.3    Ludwig, B.4    Strauer, B.5
  • 51
    • 0029554190 scopus 로고
    • Evaluation of the antihypertensive efficacy of urapidil in the treatment of hypertension emergencies [in Polish]
    • 8618814
    • K. Błaszyk S. Grajek W. Skorupski 1995 Evaluation of the antihypertensive efficacy of urapidil in the treatment of hypertension emergencies [in Polish] Pol Arch Med Wewn 94 512 517 8618814
    • (1995) Pol Arch Med Wewn , vol.94 , pp. 512-517
    • Błaszyk, K.1    Grajek, S.2    Skorupski, W.3
  • 52
    • 0035092933 scopus 로고    scopus 로고
    • Effectiveness and safety of prehospital urapidil for hypertensive emergencies
    • 10.1053/ajem.2001.20008 11239257 1:STN:280:DC%2BD3M7psl2ltw%3D%3D
    • J. Alijotas-Reig I. Bove-Farre F. de Cabo-Frances R. Angles-Coll 2001 Effectiveness and safety of prehospital urapidil for hypertensive emergencies Am J Emerg Med 19 130 133 10.1053/ajem.2001.20008 11239257 1:STN:280: DC%2BD3M7psl2ltw%3D%3D
    • (2001) Am J Emerg Med , vol.19 , pp. 130-133
    • Alijotas-Reig, J.1    Bove-Farre, I.2    De Cabo-Frances, F.3    Angles-Coll, R.4
  • 53
    • 77956216294 scopus 로고    scopus 로고
    • Hypertensive crisis. Efficacy and safe of urapidil based protocol in out-of-hospital settings
    • B. Jelakovic M. Grba-Bujevic I. Bosan-Kilibarda 2009 Hypertensive crisis. Efficacy and safe of urapidil based protocol in out-of-hospital settings J Hypertens 27 suppl.4 S122
    • (2009) J Hypertens , vol.27 , Issue.SUPPL. 4 , pp. 122
    • Jelakovic, B.1    Grba-Bujevic, M.2    Bosan-Kilibarda, I.3
  • 54
    • 0027495348 scopus 로고
    • Intravenous urapidil versus sublingual nifedipine in the treatment of hypertensive urgencies
    • 10.1016/0735-6757(93)90026-8 8240575 1:STN:280:DyaK2c%2FlvFamtQ%3D%3D
    • M.M. Hirschl D. Seidler A. Zeiner 1993 Intravenous urapidil versus sublingual nifedipine in the treatment of hypertensive urgencies Am J Emerg Med 11 653 656 10.1016/0735-6757(93)90026-8 8240575 1:STN:280:DyaK2c%2FlvFamtQ%3D%3D
    • (1993) Am J Emerg Med , vol.11 , pp. 653-656
    • Hirschl, M.M.1    Seidler, D.2    Zeiner, A.3
  • 55
    • 0029763541 scopus 로고    scopus 로고
    • Efficacy of different antihypertensive drugs in the emergency department
    • 8872847
    • M.M. Hirschl D. Seidler M. Müllner 1996 Efficacy of different antihypertensive drugs in the emergency department J Hum Hypertens 10 suppl.3 S143 146 8872847
    • (1996) J Hum Hypertens , vol.10 , Issue.SUPPL. 3 , pp. 143-146
    • Hirschl, M.M.1    Seidler, D.2    Müllner, M.3
  • 56
    • 0030760447 scopus 로고    scopus 로고
    • Safety and efficacy of urapidil and sodium nitroprusside in the treatment of hypertensive emergencies
    • 10.1007/s001340050426 9310807 1:STN:280:DyaK2svls1ymsw%3D%3D
    • M.M. Hirschl M. Binder A. Bur 1997 Safety and efficacy of urapidil and sodium nitroprusside in the treatment of hypertensive emergencies Intensive Care Med 23 885 888 10.1007/s001340050426 9310807 1:STN:280:DyaK2svls1ymsw%3D%3D
    • (1997) Intensive Care Med , vol.23 , pp. 885-888
    • Hirschl, M.M.1    Binder, M.2    Bur, A.3
  • 57
    • 33747665560 scopus 로고    scopus 로고
    • Comparison of intravenous urapidil and oral captopril in patients with hypertensive urgencies
    • 10.1038/sj.jhh.1002063 16826189 1:CAS:528:DC%2BD28XosVSjsr0%3D
    • C. Woisetschläger A. Bur M. Vlcek U. Derhaschnig A.N. Laggner M.M. Hirschl 2006 Comparison of intravenous urapidil and oral captopril in patients with hypertensive urgencies J Hum Hypertens 20 707 709 10.1038/sj.jhh.1002063 16826189 1:CAS:528:DC%2BD28XosVSjsr0%3D
    • (2006) J Hum Hypertens , vol.20 , pp. 707-709
    • Woisetschläger, C.1    Bur, A.2    Vlcek, M.3    Derhaschnig, U.4    Laggner, A.N.5    Hirschl, M.M.6
  • 58
    • 0025613324 scopus 로고
    • Acute haemodynamic effects of urapidil and nifedipine in hypertensive urgencies and emergencies
    • 10.2165/00003495-199000404-00016 2092969
    • F. Späh K.D. Grosser G. Thieme 1990 Acute haemodynamic effects of urapidil and nifedipine in hypertensive urgencies and emergencies Drugs 40 suppl.4 58 59 10.2165/00003495-199000404-00016 2092969
    • (1990) Drugs , vol.40 , Issue.SUPPL. 4 , pp. 58-59
    • Späh, F.1    Grosser, K.D.2    Thieme, G.3
  • 59
    • 0031965412 scopus 로고    scopus 로고
    • Treatment of hypertension in patients with preeclampsia: A prospective parallel-group study comparing dihydralazine with urapidil
    • 10.1093/ndt/13.2.316 9509441 1:CAS:528:DyaK1cXhsF2ksbo%3D
    • J. Wacker P. Werner I. Walter-Sack G. Bastert 1998 Treatment of hypertension in patients with preeclampsia: a prospective parallel-group study comparing dihydralazine with urapidil Nephrol Dial Transplant 13 318 325 10.1093/ndt/13.2.316 9509441 1:CAS:528:DyaK1cXhsF2ksbo%3D
    • (1998) Nephrol Dial Transplant , vol.13 , pp. 318-325
    • Wacker, J.1    Werner, P.2    Walter-Sack, I.3    Bastert, G.4
  • 60
    • 33747047580 scopus 로고    scopus 로고
    • Antihypertensive therapy in patients with preeclampsia: A prospective randomised multicentre study comparing dihydralazine with urapidil
    • 10.1016/j.ejogrb.2005.09.013 16253414 1:CAS:528:DC%2BD28XotV2nurc%3D
    • J.R. Wacker B.K. Wagner V. Briese 2006 Antihypertensive therapy in patients with preeclampsia: A prospective randomised multicentre study comparing dihydralazine with urapidil Eur J Obstet Gynecol Reprod Biol 127 160 165 10.1016/j.ejogrb.2005.09.013 16253414 1:CAS:528:DC%2BD28XotV2nurc%3D
    • (2006) Eur J Obstet Gynecol Reprod Biol , vol.127 , pp. 160-165
    • Wacker, J.R.1    Wagner, B.K.2    Briese, V.3
  • 61
    • 0034780095 scopus 로고    scopus 로고
    • Effect of Urapidil in antihypertensive therapy of preeclampsia on newborns [in German]
    • 10.1055/s-2001-18226 11709746 1:STN:280:DC%2BD3MnmtlWitA%3D%3D
    • M. Schulz J. Wacker G. Bastert 2001 Effect of Urapidil in antihypertensive therapy of preeclampsia on newborns [in German] Zentralbl Gynakol 123 529 533 10.1055/s-2001-18226 11709746 1:STN:280: DC%2BD3MnmtlWitA%3D%3D
    • (2001) Zentralbl Gynakol , vol.123 , pp. 529-533
    • Schulz, M.1    Wacker, J.2    Bastert, G.3
  • 62
    • 84868350106 scopus 로고    scopus 로고
    • DHLR - Deutsche Hypertonie Gesellschaft
    • Deutsche Hochdruckliga e.V Heidelberg, Germany Available at: Accessed:May24,2010
    • Deutsche Hochdruckliga e.V. DHLR - Deutsche Hypertonie Gesellschaft. Leitlinien zur behandlung der arteriellen hypertonie. Heidelberg, Germany, 2008. Available at: www.hochdruckliga.de. Accessed: May 24, 2010.
    • (2008) Leitlinien Zur Behandlung der Arteriellen Hypertonie
  • 63
    • 14344279862 scopus 로고    scopus 로고
    • Efficacy of a single dose of urapidil for preventing arterial hypertension during the pre-bypass period in coronary surgery
    • 11103114 1:STN:280:DC%2BD3M%2FosFWjsg%3D%3D
    • M. Olmos M.A. Vidarte J.A. Ballester J. Lasuen A. Escobar 2000 Efficacy of a single dose of urapidil for preventing arterial hypertension during the pre-bypass period in coronary surgery Rev Esp Anestesiol Reanim 47 337 342 11103114 1:STN:280:DC%2BD3M%2FosFWjsg%3D%3D
    • (2000) Rev Esp Anestesiol Reanim , vol.47 , pp. 337-342
    • Olmos, M.1    Vidarte, M.A.2    Ballester, J.A.3    Lasuen, J.4    Escobar, A.5
  • 64
    • 0019480940 scopus 로고
    • Control of hypertension during cardiopulmonary bypass with urapidil and phentolamine
    • 7197959 1:STN:280:DyaL38%2FmvVKrsA%3D%3D
    • E. Gob A. Barankay J.A. Richter 1981 Control of hypertension during cardiopulmonary bypass with urapidil and phentolamine Arzneimittelforschung 31 1479 1481 7197959 1:STN:280:DyaL38%2FmvVKrsA%3D%3D
    • (1981) Arzneimittelforschung , vol.31 , pp. 1479-1481
    • Gob, E.1    Barankay, A.2    Richter, J.A.3
  • 65
    • 0025606687 scopus 로고
    • Urapidil versus clonidine. Acute haemodynamic effects during control of intraoperative hypertensive episodes
    • 10.2165/00003495-199000404-00024 2092976
    • W. Hess 1990 Urapidil versus clonidine. Acute haemodynamic effects during control of intraoperative hypertensive episodes Drugs 40 suppl.4 77 79 10.2165/00003495-199000404-00024 2092976
    • (1990) Drugs , vol.40 , Issue.SUPPL. 4 , pp. 77-79
    • Hess, W.1
  • 66
    • 0022362216 scopus 로고
    • Comparison of phentolamine and urapidil in controlling acute intra-operative hypertension in patients subjected to coronary artery bypass surgery
    • 3874774 1:STN:280:DyaL2M3lslGmtw%3D%3D
    • W. Hess U. Schulte-Sasse J. Tarnow S. Veit 1985 Comparison of phentolamine and urapidil in controlling acute intra-operative hypertension in patients subjected to coronary artery bypass surgery Eur J Anaesthesiol 2 21 27 3874774 1:STN:280:DyaL2M3lslGmtw%3D%3D
    • (1985) Eur J Anaesthesiol , vol.2 , pp. 21-27
    • Hess, W.1    Schulte-Sasse, U.2    Tarnow, J.3    Veit, S.4
  • 67
    • 0028947493 scopus 로고
    • The influence of ketanserin or urapidil on haemodynamics, stress response and kidney function during operations for myocardial revascularisation
    • 10.1111/j.1365-2044.1995.tb04606.x 7747847 1:STN:280:DyaK2M3ms1Ojsw%3D%3D
    • A. Petry H. Wulf M. Baumgartel 1995 The influence of ketanserin or urapidil on haemodynamics, stress response and kidney function during operations for myocardial revascularisation Anaesthesia 50 312 316 10.1111/j.1365-2044. 1995.tb04606.x 7747847 1:STN:280:DyaK2M3ms1Ojsw%3D%3D
    • (1995) Anaesthesia , vol.50 , pp. 312-316
    • Petry, A.1    Wulf, H.2    Baumgartel, M.3
  • 68
    • 0027991094 scopus 로고
    • Comparison of the effects of urapidil and nitroprusside on hemodynamics and myocardial function in hypertension following cardiac surgery
    • 7804510
    • J.G. van der Stroom H.B. Van Wezel J.J. Koolen C.A. Visser P.A. Van Zwieten 1994 Comparison of the effects of urapidil and nitroprusside on hemodynamics and myocardial function in hypertension following cardiac surgery Blood Press Suppl 4 31 38 7804510
    • (1994) Blood Press Suppl , vol.4 , pp. 31-38
    • Van Der Stroom, J.G.1    Van Wezel, H.B.2    Koolen, J.J.3    Visser, C.A.4    Van Zwieten, P.A.5
  • 69
    • 12644255695 scopus 로고    scopus 로고
    • A randomized multicenter double-blind comparison of urapidil and ketanserin in hypertensive patients after coronary artery surgery
    • 10.1016/S1053-0770(97)90166-X 9327314
    • J.G. van der Stroom H.B. van Wezel J.J. Langemeijer 1997 A randomized multicenter double-blind comparison of urapidil and ketanserin in hypertensive patients after coronary artery surgery J Cardiothorac Vasc Anesth 11 729 736 10.1016/S1053-0770(97)90166-X 9327314
    • (1997) J Cardiothorac Vasc Anesth , vol.11 , pp. 729-736
    • Van Der Stroom, J.G.1    Van Wezel, H.B.2    Langemeijer, J.J.3
  • 70
    • 9244255240 scopus 로고    scopus 로고
    • Comparison of the effects of urapidil and sodium nitroprusside on haemodynamic state, myocardial metabolism and function in patients during coronary artery surgery
    • 8688263
    • J.G. van der Stroom H.B. van Wezel I. Vergroesen 1996 Comparison of the effects of urapidil and sodium nitroprusside on haemodynamic state, myocardial metabolism and function in patients during coronary artery surgery Br J Anaesth 76 645 651 8688263
    • (1996) Br J Anaesth , vol.76 , pp. 645-651
    • Van Der Stroom, J.G.1    Van Wezel, H.B.2    Vergroesen, I.3
  • 71
    • 0025252176 scopus 로고
    • Effects of urapidil, ketanserin and sodium nitroprusside on venous admixture and arterial oxygenation following coronary artery bypass grafting
    • 10.1093/bja/64.4.493 2334625 1:STN:280:DyaK3c3ktFOksw%3D%3D
    • T. Mollhoff H. Van Aken J.P. Mulier E. Muller P. Lauwers 1990 Effects of urapidil, ketanserin and sodium nitroprusside on venous admixture and arterial oxygenation following coronary artery bypass grafting Br J Anaesth 64 493 497 10.1093/bja/64.4.493 2334625 1:STN:280:DyaK3c3ktFOksw%3D%3D
    • (1990) Br J Anaesth , vol.64 , pp. 493-497
    • Mollhoff, T.1    Van Aken, H.2    Mulier, J.P.3    Muller, E.4    Lauwers, P.5
  • 72
    • 0027241928 scopus 로고
    • Blood pressure management during aortic surgery - Urapidil compared to isosorbide dinitrate
    • 10.1016/1053-0770(93)90004-5 8518372
    • J. van Hemelrijck P. Waets H. van Aken H. Lacroix A. Nevelsteen R. Suy 1993 Blood pressure management during aortic surgery - Urapidil compared to isosorbide dinitrate J Cardiothorac Vasc Anesth 7 273 278 10.1016/1053-0770(93) 90004-5 8518372
    • (1993) J Cardiothorac Vasc Anesth , vol.7 , pp. 273-278
    • Van Hemelrijck, J.1    Waets, P.2    Van Aken, H.3    Lacroix, H.4    Nevelsteen, A.5    Suy, R.6
  • 73
    • 77956222465 scopus 로고
    • Urapidil as a supplement to neuroleptanalgesia during neuroanaesthesia
    • J. Zander C. Puchstein H. van Aken P. Lawin 1984 Urapidil as a supplement to neuroleptanalgesia during neuroanaesthesia Br J Anaesth 56 1304 1305
    • (1984) Br J Anaesth , vol.56 , pp. 1304-1305
    • Zander, J.1    Puchstein, C.2    Van Aken, H.3    Lawin, P.4
  • 74
    • 0021235468 scopus 로고
    • The use of urapidil in the postoperative period
    • 6465511 1:STN:280:DyaL2c3nvVeitQ%3D%3D
    • C. Puchstein H. Van Aken J. Zander P. Lawin 1984 The use of urapidil in the postoperative period Anaesthesist 33 224 227 6465511 1:STN:280: DyaL2c3nvVeitQ%3D%3D
    • (1984) Anaesthesist , vol.33 , pp. 224-227
    • Puchstein, C.1    Van Aken, H.2    Zander, J.3    Lawin, P.4
  • 75
    • 69549126226 scopus 로고    scopus 로고
    • Preparation for surgery of phaeochromocytoma by blockade of alpha-adrenergic receptors with urapidil: What dose
    • 10.1038/jhh.2008.172 19225531 1:CAS:528:DC%2BD1MXhtValtr3E
    • P. Gosse P. Tauzin-Fin M.B. Sesay A. Sautereau P. Ballanger 2009 Preparation for surgery of phaeochromocytoma by blockade of alpha-adrenergic receptors with urapidil: what dose J Hum Hypertens 23 605 609 10.1038/jhh.2008.172 19225531 1:CAS:528:DC%2BD1MXhtValtr3E
    • (2009) J Hum Hypertens , vol.23 , pp. 605-609
    • Gosse, P.1    Tauzin-Fin, P.2    Sesay, M.B.3    Sautereau, A.4    Ballanger, P.5
  • 76
    • 0028808759 scopus 로고
    • Potential beneficial effects of urapidil in primary and secondary prevention of stroke
    • 8535545 1:STN:280:DyaK287is1KnsQ%3D%3D
    • F. Spah S.O. Walsemann 1995 Potential beneficial effects of urapidil in primary and secondary prevention of stroke Blood Press Suppl 3 62 67 8535545 1:STN:280:DyaK287is1KnsQ%3D%3D
    • (1995) Blood Press Suppl , vol.3 , pp. 62-67
    • Spah, F.1    Walsemann, S.O.2
  • 77
    • 0025216542 scopus 로고
    • Der einfluss von nifidepin und urapidil auf die autoregulation der zerebralen durchbtuling in gegenwart einer intrakraniellen raumforderung
    • 10.1055/s-2007-1001037 2360708 1:STN:280:DyaK3c3pslekug%3D%3D
    • R. Wusten J. Hemelrijck M. Mattheussen T. Lauvers C. Anger H. van Aken 1990 Der einfluss von nifidepin und urapidil auf die autoregulation der zerebralen durchbtuling in gegenwart einer intrakraniellen raumforderung Anasth Intensivther Notfallmed 25 140 145 10.1055/s-2007-1001037 2360708 1:STN:280:DyaK3c3pslekug%3D%3D
    • (1990) Anasth Intensivther Notfallmed , vol.25 , pp. 140-145
    • Wusten, R.1    Hemelrijck, J.2    Mattheussen, M.3    Lauvers, T.4    Anger, C.5    Van Aken, H.6
  • 78
    • 0026003258 scopus 로고
    • Neuroprotective properties of 5-HT1A receptor agonists in rodent models of focal and global cerebral ischemia
    • 10.1016/0014-2999(91)90717-5 1800118 1:CAS:528:DyaK38XhsFKrug%3D%3D
    • J.H. Prehn C. Backhauss C. Karkoutly 1991 Neuroprotective properties of 5-HT1A receptor agonists in rodent models of focal and global cerebral ischemia Eur J Pharmacol 203 213 222 10.1016/0014-2999(91)90717-5 1800118 1:CAS:528:DyaK38XhsFKrug%3D%3D
    • (1991) Eur J Pharmacol , vol.203 , pp. 213-222
    • Prehn, J.H.1    Backhauss, C.2    Karkoutly, C.3
  • 79
    • 10744221456 scopus 로고    scopus 로고
    • European Stroke Initiative Recommendations for Stroke Management-update 2003
    • European Stroke Initiative Executive Committee. 10.1159/000072554
    • European Stroke Initiative Executive Committee. 2003 European Stroke Initiative Recommendations for Stroke Management-update 2003 Cerebrovasc Dis 16 311 337 10.1159/000072554
    • (2003) Cerebrovasc Dis , vol.16 , pp. 311-337
  • 80
    • 41949133660 scopus 로고    scopus 로고
    • Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): A randomised pilot trial
    • 10.1016/S1474-4422(08)70069-3 18396107
    • C.S. Anderson Y. Huang J.G. Wang 2008 Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomised pilot trial Lancet Neurol 7 391 399 10.1016/S1474-4422(08)70069-3 18396107
    • (2008) Lancet Neurol , vol.7 , pp. 391-399
    • Anderson, C.S.1    Huang, Y.2    Wang, J.G.3
  • 81
    • 0034685403 scopus 로고    scopus 로고
    • Major cardiovascular events in hypertensive patients randomized to doxazosin vs. chlorthalidone: The antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT)
    • ALLHAT Collaborative Research Group. 10.1001/jama.283.15.1967
    • ALLHAT Collaborative Research Group. 2000 Major cardiovascular events in hypertensive patients randomized to doxazosin vs. chlorthalidone: the antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT) JAMA 283 1967 1975 10.1001/jama.283.15.1967
    • (2000) JAMA , vol.283 , pp. 1967-1975
  • 82
    • 0042835370 scopus 로고    scopus 로고
    • Diuretics versus alpha blockers as first-step antihypertensive therapy
    • ALLHAT officerscoordinators for the ALLHAT Collaborative Research Group. 10.1161/01.HYP.0000086521.95630.5A 1:CAS:528:DC%2BD3sXmslSju70%3D
    • ALLHAT officerscoordinators for the ALLHAT Collaborative Research Group. 2003 Diuretics versus alpha blockers as first-step antihypertensive therapy Hypertension 42 239 246 10.1161/01.HYP.0000086521.95630.5A 1:CAS:528: DC%2BD3sXmslSju70%3D
    • (2003) Hypertension , vol.42 , pp. 239-246
  • 83
    • 0347423198 scopus 로고    scopus 로고
    • Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure
    • Joint National Committee on Prevention, Detection, Evaluation,Treatment of High Blood Pressure. National Heart, Lung,Blood Institute; National High Blood Pressure Education Program Coordinating Committee. 10.1161/01.HYP. 0000107251.49515.c2 14656957 1:CAS:528:DC%2BD3sXpsVGisL4%3D
    • A.V. Chobanian G.L. Bakris H.R. Black Joint National Committee on Prevention, Detection, Evaluation,Treatment of High Blood Pressure. National Heart, Lung,Blood Institute; National High Blood Pressure Education Program Coordinating Committee 2003 Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure Hypertension 42 1206 1252 10.1161/01.HYP.0000107251.49515.c2 14656957 1:CAS:528:DC%2BD3sXpsVGisL4%3D
    • (2003) Hypertension , vol.42 , pp. 1206-1252
    • Chobanian, A.V.1    Bakris, G.L.2    Black, H.R.3
  • 84
    • 50949084105 scopus 로고    scopus 로고
    • Effect of doxazosin gastrointestinal therapeutic system as third-line antihypertensive therapy on blood pressure and lipids in the Anglo-Scandinavian Cardiac Outcomes Trial
    • 10.1161/CIRCULATIONAHA.107.737957 18559700 1:CAS:528:DC%2BD1cXnsFKqsrY%3D
    • N. Chapman C.L. Chang B. Dahlöf 2008 Effect of doxazosin gastrointestinal therapeutic system as third-line antihypertensive therapy on blood pressure and lipids in the Anglo-Scandinavian Cardiac Outcomes Trial Circulation 118 42 48 10.1161/CIRCULATIONAHA.107.737957 18559700 1:CAS:528:DC%2BD1cXnsFKqsrY%3D
    • (2008) Circulation , vol.118 , pp. 42-48
    • Chapman, N.1    Chang, C.L.2    Dahlöf, B.3
  • 85
    • 69249147910 scopus 로고    scopus 로고
    • Safety and efficacy of doxazosin as "add-on" antihypertensive therapy in mild to moderate heart failure patients
    • 10.2143/AC.64.4.2041613 19725441
    • R. Spoladore R. Roccaforte G. Fragasso 2009 Safety and efficacy of doxazosin as "add-on" antihypertensive therapy in mild to moderate heart failure patients Acta Cardiol 64 485 491 10.2143/AC.64.4.2041613 19725441
    • (2009) Acta Cardiol , vol.64 , pp. 485-491
    • Spoladore, R.1    Roccaforte, R.2    Fragasso, G.3
  • 86
    • 0022410483 scopus 로고
    • Dynamic responses to intravenous urapidil and dihydralazine in normal subjects
    • 3880685 1:CAS:528:DyaL2MXhtVGqtb4%3D
    • G.G. Belz J.H. Matthews D. Graf 1985 Dynamic responses to intravenous urapidil and dihydralazine in normal subjects Clin Pharmacol Ther 37 48 54 3880685 1:CAS:528:DyaL2MXhtVGqtb4%3D
    • (1985) Clin Pharmacol Ther , vol.37 , pp. 48-54
    • Belz, G.G.1    Matthews, J.H.2    Graf, D.3
  • 88
    • 33846923855 scopus 로고    scopus 로고
    • Differential effects of urapidil and doxazosin on heart rate
    • 10.1007/s00228-006-0256-2 17225141 1:CAS:528:DC%2BD2sXhsV2juro%3D
    • K. Stoschitzky G. Stoschitzky M. Wonisch H. Brussee 2007 Differential effects of urapidil and doxazosin on heart rate Eur J Clin Pharmacol 63 259 262 10.1007/s00228-006-0256-2 17225141 1:CAS:528:DC%2BD2sXhsV2juro%3D
    • (2007) Eur J Clin Pharmacol , vol.63 , pp. 259-262
    • Stoschitzky, K.1    Stoschitzky, G.2    Wonisch, M.3    Brussee, H.4
  • 89
    • 0028808324 scopus 로고
    • Review of studies with urapidil in elderly hypertensives
    • 8535538 1:STN:280:DyaK287is1KgtQ%3D%3D
    • L. Hansson A. Petitet 1995 Review of studies with urapidil in elderly hypertensives Blood Press Suppl 3 21 25 8535538 1:STN:280:DyaK287is1KgtQ%3D%3D
    • (1995) Blood Press Suppl , vol.3 , pp. 21-25
    • Hansson, L.1    Petitet, A.2


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