Thermogenesis in CD-1 mice after combined chronic hypoxia and cold acclimation

Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology

Volumn 157, Issue 3, 2010, Pages 301-309

  Beaudry, Jacqueline L ^a   McClelland, Grant B ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Altitude; Brown adipose tissue; Non shivering thermogenesis; Oxygen consumption; PPAR gamma co activator 1?; Uncoupling protein

Indexed keywords

NORADRENALIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; UNCOUPLING PROTEIN 1; UNCOUPLING PROTEIN 2; UNCOUPLING PROTEIN 3; CITRATE SYNTHASE; CYTOCHROME C OXIDASE; ION CHANNEL; MESSENGER RNA; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN 3;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY TEMPERATURE; BROWN ADIPOSE TISSUE; COLD ACCLIMATIZATION; CONTROLLED STUDY; HYPOBARISM; HYPOXIA; MALE; MITOCHONDRION; MOUSE; NONHUMAN; NONSHIVERING THERMOGENESIS; NUCLEOTIDE SEQUENCE; OXYGEN CONSUMPTION; PRIORITY JOURNAL; SKELETAL MUSCLE; ACCLIMATIZATION; ANIMAL; ANOXIA; BODY COMPOSITION; CALORIMETRY; COLD; COMPLICATION; INBRED MOUSE STRAIN; METABOLISM; THERMOGENESIS;

MAMMALIA; MUS;

ACCLIMATIZATION; ADIPOSE TISSUE, BROWN; ANIMALS; ANOXIA; BODY COMPOSITION; BODY TEMPERATURE; CALORIMETRY; CITRATE (SI)-SYNTHASE; COLD TEMPERATURE; ELECTRON TRANSPORT COMPLEX IV; ION CHANNELS; MALE; MICE; MICE, INBRED STRAINS; MITOCHONDRIAL PROTEINS; MUSCLE, SKELETAL; RNA, MESSENGER; THERMOGENESIS;

EID: 77956191622     PISSN: 10964959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbpb.2010.07.004     Document Type: Article

References (41)

1. Aparecida de Franca S., Dos Santos M.P., Garofalo M.A., Navegantes L.C., Kettelhut Ido C., Lopes C.F., Kawashita N.H. Low protein diet changes the energetic balance and sympathetic activity in brown adipose tissue of growing rats. Nutrition 2009, 25:1186-1192.
2. Arany Z. PGC-1 coactivators and skeletal muscle adaptations in health and disease. Curr. Opin. Genet. Dev. 2008, 18:426-434.
3. Arany Z., Foo S.Y., Ma Y., Ruas J.L., Bommi-Reddy A., Girnun G., Cooper M., Laznik D., Chinsomboon J., Rangwala S.M., Baek K.H., Rosenzweig A., Spiegelman B.M. HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1alpha. Nature 2008, 451:1008-1012.
4. Barnd T., Skala J., Lindberg O. Changes in interscapular brown adipose tissue of the rat during perinatal and early postnatal development and after cold acclimation. I. Activities of some respiratory enzymes in the tissue. Comp. Biochem. Physiol. 1970, 33:499-508.
5. Barros R.C., Zimmer M.E., Branco L.G., Milsom W.K. Hypoxic metabolic response of the golden-mantled ground squirrel. J. Appl. Physiol. 2001, 91:603-612.
6. Biggers J.D., Ashoub M.R., McLaren A., Michie D. The growth and development of mice in three climatic environments. J. Exp. Biol. 1957, 35:144-155.
7. Bishop B., Silva G., Krasney J., Nakano H., Roberts A., Farkas G., Rifkin D., Shucard D. Ambient temperature modulates hypoxic-induced changes in rat body temperature and activity differentially. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2001, 280:R1190-R1196.
8. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72:248-254.
9. Cannon B., Nedergaard J. Brown adipose tissue: function and physiological significance. Physiol. Rev. 2004, 84:277-359.
10. Chappell M.A. Maximum oxygen consumption during exercise and cold exposure in deer mice, Peromyscus maniculatus. Respir. Physiol. 1984, 55:367-377.
11. Chappell M.A., Hammond K.A. Maximal aerobic performance of deer mice in combined cold and exercise challenges. J. Comp. Physiol. B 2004, 174:41-48.
12. Cline G.W. Tough love: left out in the cold, but not abandoned, by UCP3. J. Appl. Physiol. 2006, 101:12-13.
13. Depocas F., Hart J.S., Heroux O. Cold acclimation and the electromyogram of unanesthetized rats. J. Appl. Physiol. 1956, 9:404-408.
14. Foster D.O. Quantitative contribution of brown adipose tissue thermogenesis to overall metabolism. Can. J. Biochem. Cell Biol. 1984, 62:618-622.
15. Fukuda R., Zhang H., Kim J.W., Shimoda L., Dang C.V., Semenza G.L. HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells. Cell 2007, 129:111-122.
16. Gautier H., Bonora M., M'Barek S.B., Sinclair J.D. Effects of hypoxia and cold acclimation on thermoregulation in the rat. J. Appl. Physiol. 1991, 71:1355-1363.
17. Gusztak R.W., Macarthur R.A., Campbell K.L. Bioenergetics and thermal physiology of American water shrews (Sorex palustris). J. Comp. Physiol. B 2005, 175:87-95.
18. Hemingway A. Shivering. Physiol. Rev. 1963, 43:397-422.
19. Himms-Hagen J. Brown adipose tissue metabolism and thermogenesis. Annu. Rev. Nutr. 1985, 5:69-94.
20. Johnson E. Seasonal Changes in the Skin of Mammals 1977, 39:373-404.
21. Klaus S., Munzberg H., Truloff C., Heldmaier G. Physiology of transgenic mice with brown fat ablation: obesity is due to lowered body temperature. Am. J. Physiol. 1998, 274:R287-R293.
22. Lin B., Coughlin S., Pilch P.F. Bidirectional regulation of uncoupling protein-3 and GLUT-4 mRNA in skeletal muscle by cold. Am. J. Physiol. 1998, 275:E386-E391.
23. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2-deltadelta Ct method. Methods 2001, 25:402-408.
24. Lowell B.B., Spiegelman B.M. Towards a molecular understanding of adaptive thermogenesis. Nature 2000, 404:652-660.
25. Madden C.J., Morrison S.F. Hypoxic activation of arterial chemoreceptors inhibits sympathetic outflow to brown adipose tissue in rats. J. Physiol. 2005, 566:559-573.
26. Madsen L., Pedersen L.M., Lillefosse H.H., Fjaere E., Bronstad I., Hao Q., Petersen R.K., Hallenborg P., Ma T., De Matteis R., Araujo P., Mercader J., Bonet M.L., Hansen J.B., Cannon B., Nedergaard J., Wang J., Cinti S., Voshol P., Døskeland S.O., Kristiansen K. UCP1 induction during recruitment of brown adipocytes in white adipose tissue is dependent on cyclooxygenase activity. PLoS ONE 2010, 5:E11391.
27. McClelland G.B., Hochachka P.W., Weber J.M. Carbohydrate utilization during exercise after high-altitude acclimation: a new perspective. Proc. Natl Acad. Sci. USA 1998, 95:10288-10293.
28. Monemdjou S., Kozak L.P., Harper M.E. Mitochondrial proton leak in brown adipose tissue mitochondria of UCP1-deficient mice is GDP insensitive. Am. J. Physiol. 1999, 276:E1073-E1082.
29. Mortola J.P., Seifert E.L. Hypoxic depression of circadian rhythms in adult rats. J. Appl. Physiol. 2000, 88:365-368.
30. Mortola J.P., Naso L. Thermogenesis in newborn rats after prenatal or postnatal hypoxia. J. Appl. Physiol. 1998, 85:84-90.
31. Mousel M.R., Stroup W.W., Nielsen M.K. Locomotor activity, core body temperature, and circadian rhythms in mice selected for high or low heat loss. J. Anim. Sci. 2001, 79:861-868.
32. Ray A.D., Roberts A.J., Lee S.D., Farkas G.A., Michlin C., Rifkin D.I., Ostrow P.T., Krasney J.A. Exercise delays the hypoxic thermal response in rats. J. Appl. Physiol. 2003, 95:272-278.
33. Rezende E.L., Chappell M.A., Hammond K.A. Cold-acclimation in peromyscus: temporal effects and individual variation in maximum metabolism and ventilatory traits. J. Exp. Biol. 2004, 207:295-305.
34. Romanovsky A.A., Ivanov A.I., Shimansky Y.P. Selected contribution: ambient temperature for experiments in rats: a new method for determining the zone of thermal neutrality. J. Appl. Physiol. 2002, 92:2667-2679.
35. Tattersall G.J., Milsom W.K. Hypoxia reduces the hypothalamic thermogenic threshold and thermosensitivity. J. Physiol. 2009, 587:5259-5274.
36. Vaillancourt E., Haman F., Weber J.M. Fuel selection in Wistar rats exposed to cold: Shivering thermogenesis diverts fatty acids from re-esterification to oxidation. J. Physiol. 2009, 587:4349-4359.
37. Wickler S.J. Seasonal changes in enzymes of aerobic heat production in the white-footed mouse. Am. J. Physiol. 1981, 240:R289-R294.
38. 2, and evaporative water loss with a flow-through mask. J. Appl. Physiol. 1977, 42:120-123.
39. Wu Z., Puigserver P., Andersson U., Zhang C., Adelmant G., Mootha V., Troy A., Cinti S., Lowell B., Scarpulla R.C., Spiegelman B.M. Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell 1999, 98:115-124.
40. Wunder B.A., Gettinger R.D. Effects of body mass and temperature acclimation on the non-shivering thermogenic response of small mammals. Adaptation to the Cold 1996, 131-139. University of New England Press, 131-139. F. Geiser, A.J. Hulbert, S.C. Nicol (Eds.).
41. Zhou F., Zhu X., Castellani R.J., Stimmelmayr R., Perry G., Smith M.A., Drew K.L. Hibernation, a model of neuroprotection. Am. J. Pathol. 2001, 158:2145-2151.