Thermogenesis in newborn rats after prenatal or postnatal hypoxia

Journal of Applied Physiology

Volumn 85, Issue 1, 1998, Pages 84-90

  Mortola, Jacopo P ^a   Naso, Lina ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Brown adipose tissue; Hypercapnia; Perinatal hypoxia; Uncoupling protein thermogenin; Undernourishment

Indexed keywords

CARBON DIOXIDE; MUSCLE PROTEIN; OXYGEN; UNCOUPLING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; ENVIRONMENTAL TEMPERATURE; HYPERCAPNIA; MITOCHONDRIAL RESPIRATION; NEWBORN; NEWBORN HYPOXIA; NONHUMAN; OXYGEN BLOOD LEVEL; OXYGEN CONSUMPTION; PERINATAL PERIOD; PRENATAL PERIOD; PRIORITY JOURNAL; RAT; THERMOGENESIS;

EID: 0031829971     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1998.85.1.84     Document Type: Article

References (37)

1. Alberts, J. R. Huddling by rat pups: group behavioral mechanisms of temperature regulation and energy conservation. J. Comp. Physiol. Psychol. 92: 231-245, 1978.
2. Benedek, G., M. Szikszay, and F. Obal. Stress-related changes of opiate sensitivity in thermoregulation. Life Sci. 33, Suppl. 1: 591-593, 1983.
3. Bertin, R., F. De Marco, I. Mouroux, and R. Portet. Postnatal development of nonshivering thermogenesis in rats: effects of rearing temperature. J. Dev. Physiol. (Eynsham) 19: 9-15, 1993.
4. Briese, E. Emotional hyperthermia and performance in humans. Physiol. Behav. 58: 615-618, 1995.
5. Brück, K. Neonatal thermal regulation. In: Fetal and Neonatal Physiology, edited by R. A. Polin and W. W. Fox. Philadelphia, PA: Saunders, 1992, chapt. 48, p. 488-515.
6. Bukowiecki, L., A. J. Collet, N. Follea, G. Guay, and L. Jahjah. Brown adipose tissue hyperplasia: a fundamental mechanism of adaptation to cold and hyperphagia. Am. J. Physiol. 242 (Endocrinol. Metab. 5): E353-E359, 1982.
7. Bukowiecki, L. J., A. Géloën, and A. J. Collet. Proliferation and differentiation of brown adipocytes from interstitial cells during cold acclimation. Am. J. Physiol. 250 (Cell Physiol. 19): C880-C887, 1986.
8. Cannon, B., and J. Nedergaard. Biochemical aspects of acclimation to cold. J. Therm. Biol. 8: 85-90, 1983.
9. Desautels, M., R. A. Dulos, and B. Mozaffari. Selective loss of uncoupling protein from mitochondria of surgically denervated brown adipose tissue of cold-acclimated mice. Biochem. Cell Biol. 64: 1125-1134, 1986.
10. Dotta, A., and J. P. Mortola. Effects of hyperoxia on the metabolic response to cold of the newborn rat. J. Dev. Physiol. (Eynsham) 17: 247-250, 1992.
11. Frappell, P., C. Lanthier, R. V. Baudinette, and J. P. Mortola. Metabolism and ventilation in acute hypoxia: a comparative analysis in small mammalian species. Am. J. Physiol. 262 (Regulatory Integrative Comp. Physiol. 31): R1040-R1046, 1992.
12. Gleed, R. D., and J. P. Mortola. Ventilation in newborn rats after gestation at simulated high altitude. J. Appl. Physiol. 70: 1146-1151, 1991.
13. Markussen, N. H., and N. A. Oristland. Metabolic depression and heat balance in starving Wistar rats. Comp. Biochem. Physiol. A 84: 771-776, 1986.
14. Morroni, M., G. Barbatelli, M. C. Zingaretti, and S. Cinti. Immunohistochemical, ultrastructural and morphometric evidence for brown adipose tissue recruitment due to cold acclimation in old rats. Int. J. Obes. 19: 126-131, 1995.
15. Mortola, J. P., and A. Dotta. Effects of hypoxia and ambient temperature on gaseous metabolism of newborn rats. Am. J. Physiol. 263 (Regulatory Integrative Comp. Physiol. 32): R267-R272, 1992.
16. Mortola, J. P., P. B. Frappell, A. Dotta, T. Matsuoka, G. Fox, S. Weeks, and D. Mayer. Ventilatory and metabolic responses to acute hyperoxia in newborns. Am. Rev. Respir. Dis. 146: 11-15, 1992.
17. Mortola, J. P., and H. Gautier. Interaction between metabolism and ventilation: effects of respiratory gases and temperature. In: Regulation of Breathing (2nd ed.), edited by J. A. Dempsey and A. I. Pack. New York: Dekker, 1995, vol. 79, chapt. 23, p. 1011-1064. (Lung Biol. Health Dis. Ser.)
18. Mortola, J. P., C. A. Morgan, and V. Virgona. Respiratory adaptation to chronic hypoxia in newborn rats. J. Appl. Physiol. 61: 1329-1336, 1986.
19. Mortola, J. P., and L. Naso. Electrophoretic analysis of contractile proteins of the diaphragm in chronically hypoxic rats. Am. J. Physiol. 269 (Lung Cell. Mol. Physiol. 13): L371-L376, 1995.
20. Mortola, J. P., and L. Naso. Brown adipose tissue and its uncoupling protein in chronically hypoxic rats. Clin. Sci. (Colch.) 93: 349-354, 1997.
21. Mortola, J. P., and S. M. Tenney. Effects of hyperoxia on ventilatory and metabolic rates in newborn mice. Respir. Physiol. 63: 267-274, 1986.
22. Mortola, J. P., L. Xu, and A.-M. Lauzon. Body weight, lung and heart weight, and DNA content in newborn rats exposed to different levels of chronic hypoxia. Can. J. Physiol. Pharmacol. 68: 1590-1594, 1990.
23. Puigserver, P., D. Herron, M. Gianotti, A. Palou, B. Cannon, and J. Nedergaard. Induction and degradation of the uncoupling protein thermogenin in brown adipocytes in vitro and in vivo. Biochem. J. 284: 393-398, 1992.
24. Rohlicek, C. V., C. Saiki, T. Matsuoka, and J. P. Mortola. Oxygen transport in conscious newborn dogs during hypoxic hypometabolism. J. Appl. Physiol. 84: 763-768, 1998.
25. Rothwell, N. J., and M. J. Stock. Effect of chronic food restriction on energy balance, thermogenic capacity, and brown-adipose-tissue activity in the rat. Biosci. Rep. 2: 543-549, 1982.
26. 2 on the metabolic and ventilatory responses to ambient temperature in conscious adult and newborn rats. J. Physiol. (Lond.) 491: 261-269, 1996.
27. Schneider, W. C. Determination of nucleic acids by pentose analysis. Methods Enzymol. 3: 680-684, 1957.
28. Siyamak, A. Y., and I. A. Macdonald. Sub-acute underfeeding but not acute starvation reduces noradrenaline induced thermogenesis in the conscious rat. Int. J. Obes. 16: 113-117, 1992.
29. Skála, J., and P. Hahn. Changes in interscapular brown adipose tissue of the rat during perinatal and early postnatal development after cold acclimation. VI. Effect of hormones and ambient temperature. Int. J. Biochem. 5: 95-106, 1974
30. Soppela, P., M. Nieminen, S. Saarela, J. S. Keith, J. N. Morrison, and P. Trayhurn. Development of uncoupling protein in adipose tissues of reindeer. Biochem. Soc. Trans. 18: 1270-1271, 1990.
31. Soppela, P., R. Sormunen, S. Saarela, P. Huttunen, and M. Nieminen. Localization, cellular morphology and respiratory capacity of "brown" adipose tissue in newborn reindeer. Comp. Biochem. Physiol. A 101A: 281-293, 1992.
32. Talan, M. I., S. A. Kirov, L. A. Clow, and N. A. Kosheleva. Cold acclimation-associated changes in brown adipose tissue do not necessarily indicate an increase of nonshivering thermogenesis in C57BL/6J mice. Physiol. Behav. 60: 1285-1289, 1996.
33. Taylor, P. M. Oxygen consumption in new-born rats. J. Physiol. (Lond.) 154: 153-168, 1960.
34. Tornatzky, W., and K. A. Miczek. Long-term impairment of autonomie circadian rhythms after brief intermittent social stress. Physiol. Behav. 53: 983-993, 1993.
35. Vellucci, S. V., and R. F. Parrott. Prostaglandin-dependent c-Fos expression in the median preoptic nucleus of pigs subjected to restraint: correlation with hyperthermia. Neurosci. Lett. 198: 49-51, 1995.
36. Yoshida, T., N. Sakane, T. Umekawa, and M. Kondo. Effect of nicotine on sympathetic nervous system activity of mice subjected to immobilization stress. Physiol. Behav. 55: 53-57, 1994.
37. Zethof, T. J., J. A. Van der Heyden, J. T. Tolboom, and B. Olivier. Stress-induced hyperthermia in mice: a methodological study. Physiol. Behav. 55: 109-115, 1994.