Effectiveness of budesonide-succinate-dextran conjugate as a novel prodrug of budesonide against acetic acid-induced colitis in rats

International Journal of Colorectal Disease

Volumn 25, Issue 10, 2010, Pages 1159-1165

  Varshosaz, Jaleh ^a   Emami, Jaber ^a   Fassihi, Afshin ^a   Tavakoli, Naser ^a   Minaiyan, Mohsen ^a   Ahmadi, Fatemeh ^a   Mahzouni, Parvin ^a   Dorkoosh, Farid ^b  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Budesonide; Colon drug delivery; Experimental colitis; Prodrugs

Indexed keywords

ACETIC ACID; BUDESONIDE; BUDESONIDE SUCCINATE DEXTRAN CONJUGATE; ENEMA; GASTROINTESTINAL AGENT; HYDROCORTISONE ACETATE; MESALAZINE; PREDNISOLONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOODY DIARRHEA; COLITIS; CONTROLLED STUDY; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG FORMULATION; HISTOPATHOLOGY; IN VIVO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TREATMENT RESPONSE; ULCERATIVE COLITIS;

ACETIC ACID; ANIMALS; ANTI-INFLAMMATORY AGENTS; BUDESONIDE; COLITIS; DEXTRANS; HYDROCORTISONE; MALE; PREDNISOLONE; PRODRUGS; RATS; RATS, WISTAR; SUCCINIC ACID;

EID: 77956191062     PISSN: 01791958     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00384-010-1026-2     Document Type: Article

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