-
1
-
-
0028832474
-
Approaches and opportunities in colon-spenlic drug delivery
-
Rubinstein A. Approaches and opportunities in colon-spenlic drug delivery. Crit Rev Ther Drug Currier Syst 1995; 12: 101-49.
-
(1995)
Crit Rev Ther Drug Currier Syst
, vol.12
, pp. 101-149
-
-
Rubinstein, A.1
-
3
-
-
0026186292
-
Colon-specific drug delivery
-
Friend DR. Colon-specific drug delivery. Adv Drug Del Rev 1991; 7: 149-99.
-
(1991)
Adv Drug del Rev
, vol.7
, pp. 149-199
-
-
Friend, D.R.1
-
4
-
-
0001359381
-
Specific delivery to the gastrointestinal tract
-
Domb AJ. ed. Chichester: John Wiley & Sons Ltd.
-
Rubinstein A, Friend DR. Specific delivery to the gastrointestinal tract. In: Domb AJ. ed. Polymeric Site-Specific Pharmacotherapy. Chichester: John Wiley & Sons Ltd. 1994: 267-313.
-
(1994)
Polymeric Site-Specific Pharmacotherapy
, pp. 267-313
-
-
Rubinstein, A.1
Friend, D.R.2
-
6
-
-
0025050623
-
Microbially controlled drug delivery to the colon
-
Rubinstein A. Microbially controlled drug delivery to the colon. Biopharm Drug Dispos 1990; 11: 465-75.
-
(1990)
Biopharm Drug Dispos
, vol.11
, pp. 465-475
-
-
Rubinstein, A.1
-
7
-
-
0020576357
-
Clinical appearance at diagnosis of ulcerative colities and Crohn's disease in a regional patient group
-
Both H. Torp-Pedersen K. Kreiner S. et al. Clinical appearance at diagnosis of ulcerative colities and Crohn's disease in a regional patient group. Scand J Gastroenterol 1983; 18: 987-91.
-
(1983)
Scand J Gastroenterol
, vol.18
, pp. 987-991
-
-
Both, H.1
Torp-Pedersen, K.2
Kreiner, S.3
-
9
-
-
0023338533
-
Biochemistry, molecular biology, and physiology of the glucocorticoid receptor
-
Gustafsson J-A. Carlstedt-Duke J. Poellinger L. et al. Biochemistry, molecular biology, and physiology of the glucocorticoid receptor. Endocr Rev 1987; 8: 185-234.
-
(1987)
Endocr Rev
, vol.8
, pp. 185-234
-
-
Gustafsson, J.-A.1
Carlstedt-Duke, J.2
Poellinger, L.3
-
10
-
-
0024523089
-
Recent insights into the structure and function of the glucocorticoid receptor
-
Distelhorst CW. Recent insights into the structure and function of the glucocorticoid receptor. J Lab Clin Med 1989; 113: 404-12.
-
(1989)
J Lab Clin Med
, vol.113
, pp. 404-412
-
-
Distelhorst, C.W.1
-
11
-
-
0017275912
-
Glucocorticosteroid therapy: Mechanisms of action and clinical considerations
-
Fauci AS. Glucocorticosteroid therapy: Mechanisms of action and clinical considerations. Ann Intern Med 1976; 84: 304-15.
-
(1976)
Ann Intern Med
, vol.84
, pp. 304-315
-
-
Fauci, A.S.1
-
12
-
-
0025067444
-
Effects of glucocorticosteroids on inflammatory cells relevant to their therapeutic applications in asthma
-
Schleimer RP. Effects of glucocorticosteroids on inflammatory cells relevant to their therapeutic applications in asthma. Am Respir Dis 1990; 141 (Suppl.): 50-60.
-
(1990)
Am Respir Dis
, vol.141
, Issue.SUPPL.
, pp. 50-60
-
-
Schleimer, R.P.1
-
14
-
-
0022545017
-
Cell-mediated immunity in gastrointestinal disease
-
MacDermoll RP. Cell-mediated immunity in gastrointestinal disease. Hum Pathol 1986; 17: 219-33.
-
(1986)
Hum Pathol
, vol.17
, pp. 219-233
-
-
MacDermoll, R.P.1
-
16
-
-
77049183727
-
Cortisone in ulcerative colitis. Preliminary report on a therapeutic trial
-
Truelove SC, Witts LJ. Cortisone in ulcerative colitis. Preliminary report on a therapeutic trial. Br Med J 1954; 2: 375-8.
-
(1954)
Br Med J
, vol.2
, pp. 375-378
-
-
Truelove, S.C.1
Witts, L.J.2
-
17
-
-
0000206329
-
An assessment of prednisolone. salazopyrin. and topical hydrocortisone hemisuecutate used as out-patient treatment of ulcerative colitis
-
Lennard-Jones JE. Longmore AJ. Newell AC. et al. An assessment of prednisolone. salazopyrin. and topical hydrocortisone hemisuecutate used as out-patient treatment of ulcerative colitis. Gut 1960; 1: 217-222.
-
(1960)
Gut
, vol.1
, pp. 217-222
-
-
Lennard-Jones, J.E.1
Longmore, A.J.2
Newell, A.C.3
-
18
-
-
0018777782
-
Clinical pharmacokineties of prednisone and prednisolone
-
Pickup ME. Clinical pharmacokineties of prednisone and prednisolone. Clin Pharmacokinet 1979; 4: 111-28.
-
(1979)
Clin Pharmacokinet
, vol.4
, pp. 111-128
-
-
Pickup, M.E.1
-
19
-
-
0018129292
-
Corticosteroids: Clinical pharmacology and therapeutic use
-
Swartz S. Dluhy R. Corticosteroids: clinical pharmacology and therapeutic use. Drugs 1978; 16: 238-55.
-
(1978)
Drugs
, vol.16
, pp. 238-255
-
-
Swartz, S.1
Dluhy, R.2
-
20
-
-
0026781164
-
Steroid complications in patients with ulcerative colitis
-
Kusunoki M. Möeslein G. Shoji Y. et al. Steroid complications in patients with ulcerative colitis. Dis Colon Rectum 1992: 35: 1003-9.
-
(1992)
Dis Colon Rectum
, vol.35
, pp. 1003-1009
-
-
Kusunoki, M.1
Möeslein, G.2
Shoji, Y.3
-
21
-
-
0018887725
-
Rectally administered prednisolone evidence for a predominantly local action
-
Lee DAH, Taylor M, James VTH, et al. Rectally administered prednisolone evidence for a predominantly local action. Gut 1980; 21: 215-18.
-
(1980)
Gut
, vol.21
, pp. 215-218
-
-
Lee, D.A.H.1
Taylor, M.2
James, V.T.H.3
-
22
-
-
0022577874
-
Effect of glucorticoids on rectal transport in normal subjects and patients with ulcerative colitis
-
Sandle GI, Hayslett JP, Binder HJ. Effect of glucorticoids on rectal transport in normal subjects and patients with ulcerative colitis. Gut 1986; 27: 309-16.
-
(1986)
Gut
, vol.27
, pp. 309-316
-
-
Sandle, G.I.1
Hayslett, J.P.2
Binder, H.J.3
-
23
-
-
7344260729
-
A comparative review of available rectal steroids in the treatment of distal disease
-
Peña AS. A comparative review of available rectal steroids in the treatment of distal disease. Res Clin Forums 1993; 15: 57-64.
-
(1993)
Res Clin Forums
, vol.15
, pp. 57-64
-
-
Peña, A.S.1
-
24
-
-
7344258867
-
Intrarectal treatment of 100 cases of ulcerative colitis with prednisolone 21-phosphate enemata
-
Flavell Matts SG, Intrarectal treatment of 100 cases of ulcerative colitis with prednisolone 21-phosphate enemata. Br Med J 1961; 2: 165-8.
-
(1961)
Br Med J
, vol.2
, pp. 165-168
-
-
Flavell Matts, S.G.1
-
25
-
-
0017235592
-
Plasma prednisolone levels after administration of prednisolone-21-phosphate as a retention enema in colitis
-
Powell-Tuck J. Lennard-Jones JE, May CS. et al. Plasma prednisolone levels after administration of prednisolone-21-phosphate as a retention enema in colitis. Br Med J 1976; 1:193-5.
-
(1976)
Br Med J
, vol.1
, pp. 193-195
-
-
Powell-Tuck, J.1
Lennard-Jones, J.E.2
May, C.S.3
-
26
-
-
0026015975
-
A controlled trial of beclomethasone versus betamethasone enemas in distal ulcerative colitis
-
Halpern Z. Sold O. Baratz M. et al. A controlled trial of beclomethasone versus betamethasone enemas in distal ulcerative colitis. J Clin Gastroenterol 1991; 13: 38-41.
-
(1991)
J Clin Gastroenterol
, vol.13
, pp. 38-41
-
-
Halpern, Z.1
Sold, O.2
Baratz, M.3
-
27
-
-
0020033314
-
Beclomethasone dipropionate enemas for treating inflammatory bowel disease without producing Cushing's syndrome or hypothalamic pituitary-adrenal suppression
-
Kumana CR, Seaton T. Casteli M. et al. Beclomethasone dipropionate enemas for treating inflammatory bowel disease without producing Cushing's syndrome or hypothalamic pituitary-adrenal suppression. Lancet 1982; 1: 579-83.
-
(1982)
Lancet
, vol.1
, pp. 579-583
-
-
Kumana, C.R.1
Seaton, T.2
Casteli, M.3
-
28
-
-
0023090478
-
Treatment of distal ulcerative colitis with beclomethasone enemas: High therapeutic efficacy without endocrine side effects
-
Bansky G. Buhler H. Stamm B. et al. Treatment of distal ulcerative colitis with beclomethasone enemas: High therapeutic efficacy without endocrine side effects. Dis Colon Rectum 1987; 30: 288-92.
-
(1987)
Dis Colon Rectum
, vol.30
, pp. 288-292
-
-
Bansky, G.1
Buhler, H.2
Stamm, B.3
-
29
-
-
0021875335
-
Therapeutic benefits from a poorly absorbed prednisolone enema in distal colitis
-
McIntyre PB. Macrae FA, Berghouse L. et al. Therapeutic benefits from a poorly absorbed prednisolone enema in distal colitis. Gut 1985; 26: 822-4.
-
(1985)
Gut
, vol.26
, pp. 822-824
-
-
McIntyre, P.B.1
Macrae, F.A.2
Berghouse, L.3
-
30
-
-
0001071854
-
Treatment of ulcerative colitis with local hydrocortisone
-
Truelove SC. Treatment of ulcerative colitis with local hydrocortisone. Br Med J 1956; 2: 1267-72.
-
(1956)
Br Med J
, vol.2
, pp. 1267-1272
-
-
Truelove, S.C.1
-
31
-
-
7344219842
-
Betamethasone enemata in ulcerative colitis
-
Matts S. Betamethasone enemata in ulcerative colitis. Gut 1962; 3: 312-14.
-
(1962)
Gut
, vol.3
, pp. 312-314
-
-
Matts, S.1
-
32
-
-
7344262518
-
Experience with short and long term courses of local adrenal steroid therapy in ulcerative colitis
-
Spencer J. Kirsner JB. Experience with short and long term courses of local adrenal steroid therapy in ulcerative colitis. Gastroenterology 1962; 6: 669-77.
-
(1962)
Gastroenterology
, vol.6
, pp. 669-677
-
-
Spencer, J.1
Kirsner, J.B.2
-
33
-
-
0014848395
-
Treatment of ulcerative colitis with hydrocortisone enemas: Relationship of hydrocortisone absorption. adrenal suppression and clinical response
-
Farmer RG. Schumacher OP. Treatment of ulcerative colitis with hydrocortisone enemas: relationship of hydrocortisone absorption. adrenal suppression and clinical response. Dis Colon Rectum 1970; 13: 355-61.
-
(1970)
Dis Colon Rectum
, vol.13
, pp. 355-361
-
-
Farmer, R.G.1
Schumacher, O.P.2
-
34
-
-
0027962564
-
Pharmacokinetics and retrograde colonic spread of budesonide enemas in patients with distal ulcerative colitis
-
Nyman-Pantelidis N. Nilsson A. Wagner ZG. et al. Pharmacokinetics and retrograde colonic spread of budesonide enemas in patients with distal ulcerative colitis. Aliment Pharmacol Ther 1994; 8: 617-22.
-
(1994)
Aliment Pharmacol Ther
, vol.8
, pp. 617-622
-
-
Nyman-Pantelidis, N.1
Nilsson, A.2
Wagner, Z.G.3
-
35
-
-
0027048907
-
Spread and distribution of 5-ASA colonic foam and 5-ASA enema in patients with ulcerative colitis
-
Campieri M. Corbelli C. Giochetti P. et al. Spread and distribution of 5-ASA colonic foam and 5-ASA enema in patients with ulcerative colitis. Dig Dis Sci 1992; 37: 1890-7.
-
(1992)
Dig Dis Sci
, vol.37
, pp. 1890-1897
-
-
Campieri, M.1
Corbelli, C.2
Giochetti, P.3
-
36
-
-
0019128167
-
Treatment of distal ulcerative colitis (proctosidmoiditis) in relapse, comparison of hydrocortisone enemas and rectal hydrocortisone foam
-
Ruddel WSJ. Dickinson RJ. Dixon MF. et al. Treatment of distal ulcerative colitis (proctosidmoiditis) in relapse, comparison of hydrocortisone enemas and rectal hydrocortisone foam. Gut 1980; 21: 885-9.
-
(1980)
Gut
, vol.21
, pp. 885-889
-
-
Ruddel, W.S.J.1
Dickinson, R.J.2
Dixon, M.F.3
-
38
-
-
0025690782
-
Overview of newer glucocorticosteroid preparations for inflammatory bowel disease
-
Brattsand R. Overview of newer glucocorticosteroid preparations for inflammatory bowel disease. Can J Gastroenterol 1990; 4: 407-14.
-
(1990)
Can J Gastroenterol
, vol.4
, pp. 407-414
-
-
Brattsand, R.1
-
40
-
-
0028096152
-
A novel dextranglucocorticosteroid prodrug accelerates healing with limited adrenal suppression in experimental colitis in rats
-
McLeod AD. Cui N. Friend DR. et al. A novel dextranglucocorticosteroid prodrug accelerates healing with limited adrenal suppression in experimental colitis in rats. Gastroenterology 1994; 106: 405-13.
-
(1994)
Gastroenterology
, vol.106
, pp. 405-413
-
-
McLeod, A.D.1
Cui, N.2
Friend, D.R.3
-
41
-
-
0027997464
-
A budesonide prodrug accelerates treatment of colitis in rats
-
Fedorak RN. Cui N. Friend DR. A budesonide prodrug accelerates treatment of colitis in rats. Gut 1994; 35: 1439-46.
-
(1994)
Gut
, vol.35
, pp. 1439-1446
-
-
Fedorak, R.N.1
Cui, N.2
Friend, D.R.3
-
42
-
-
0029020655
-
Colonic delivery of dexamethasone from a prodrug accelerates healing of experimental colitis without adrenal suppression
-
Fedorak RN. Haeberlin B. Empey I., et al. Colonic delivery of dexamethasone from a prodrug accelerates healing of experimental colitis without adrenal suppression. Gastroenterology 1995; 108: 1688-99.
-
(1995)
Gastroenterology
, vol.108
, pp. 1688-1699
-
-
Fedorak, R.N.1
Haeberlin, B.2
Empey, I.3
-
43
-
-
0020584826
-
Tixicortole pivalate. a corticosteroid with no systemic glucocorticoid effect after oral. intrarectal. and intranasal application
-
Larochelle P. DuSouich P, Bolte E. et al. Tixicortole pivalate. a corticosteroid with no systemic glucocorticoid effect after oral. intrarectal. and intranasal application. Clin Pharmacol Ther 1983; 33: 343-50.
-
(1983)
Clin Pharmacol Ther
, vol.33
, pp. 343-350
-
-
Larochelle, P.1
DuSouich, P.2
Bolte, E.3
-
44
-
-
0023239074
-
Liver metabolism of budesonide in rat. mouse. and man. Comparative aspects
-
Edsbacker S, Andersson P, Lindberg C. et al. Liver metabolism of budesonide in rat. mouse. and man. Comparative aspects. Drug Metab Dispos 1985; 15: 403-11.
-
(1985)
Drug Metab Dispos
, vol.15
, pp. 403-411
-
-
Edsbacker, S.1
Andersson, P.2
Lindberg, C.3
-
45
-
-
0021049061
-
Metabolic pathways of the topical glucocorticoid budesonide in man
-
Edsbacker S. Jonsson S. Lindberg C. et al. Metabolic pathways of the topical glucocorticoid budesonide in man. Drug Metab Dispos 1983; 11: 590-6.
-
(1983)
Drug Metab Dispos
, vol.11
, pp. 590-596
-
-
Edsbacker, S.1
Jonsson, S.2
Lindberg, C.3
-
46
-
-
0020409435
-
Pharmacokinetics and metabolism of budesonide. a selective glucocorticoid
-
Ryrfeldt A. Andersson P. Edsbacker S. et al. Pharmacokinetics and metabolism of budesonide. a selective glucocorticoid. Eur J Resp Dis 1982: 63 (Suppl. 122): 86-95.
-
(1982)
Eur J Resp Dis
, vol.63
, Issue.122 SUPPL.
, pp. 86-95
-
-
Ryrfeldt, A.1
Andersson, P.2
Edsbacker, S.3
-
47
-
-
0028841979
-
Budesonide. a review of its pharmacological and therapeutic efficacy in inflammatory bowel disease
-
Spencer CM. McTavish D. Budesonide. a review of its pharmacological and therapeutic efficacy in inflammatory bowel disease. Drugs 1995; 50: 854-72.
-
(1995)
Drugs
, vol.50
, pp. 854-872
-
-
Spencer, C.M.1
McTavish, D.2
-
48
-
-
0026731958
-
Budesonide. an updated review of its pharmacological properties and therapeutic efficacy in asthma and rhinitis
-
Borgden RN. McTavish D. Budesonide. an updated review of its pharmacological properties and therapeutic efficacy in asthma and rhinitis. Drugs 1992; 44: 375-407.
-
(1992)
Drugs
, vol.44
, pp. 375-407
-
-
Borgden, R.N.1
McTavish, D.2
-
49
-
-
0021702476
-
Budesonide: A preliminary review of its pharmacodynamic properties and therapeutic efficacy in asthma and rhinitis
-
Clissold SP. Heel RC. Budesonide: a preliminary review of its pharmacodynamic properties and therapeutic efficacy in asthma and rhinitis. Drugs 1984; 28: 485-518.
-
(1984)
Drugs
, vol.28
, pp. 485-518
-
-
Clissold, S.P.1
Heel, R.C.2
-
50
-
-
9344230405
-
Oral budesonide versus prednisolone in patients with active extensive and left-sided ulcerative colitis
-
Löfberg R. Danielsson A. Suhr O. et al. Oral budesonide versus prednisolone in patients with active extensive and left-sided ulcerative colitis. Gastroenterology 1996; 110: 17135-18.
-
(1996)
Gastroenterology
, vol.110
, pp. 17135-17218
-
-
Löfberg, R.1
Danielsson, A.2
Suhr, O.3
-
51
-
-
4243250168
-
Immunopharmacology of budesonide inhibition of pro-inflammatory cytokine secretion by IBD mononuclear phagocytes
-
Schreiber S. Schottelius A. Baumann J. et al. Immunopharmacology of budesonide inhibition of pro-inflammatory cytokine secretion by IBD mononuclear phagocytes. Gastroenterology 1996; 112: A1011.
-
(1996)
Gastroenterology
, vol.112
-
-
Schreiber, S.1
Schottelius, A.2
Baumann, J.3
-
52
-
-
7344229326
-
Pharmacokinetics and -dynamics of budesonide (BUD) after oral topical administration
-
Tromm A. Möllmann HW. Schwegler U. et al. Pharmacokinetics and -dynamics of budesonide (BUD) after oral topical administration. Gastroenterology 1995; 104: A792.
-
(1995)
Gastroenterology
, vol.104
-
-
Tromm, A.1
Möllmann, H.W.2
Schwegler, U.3
-
53
-
-
7344243186
-
Multiple oral application of budesonide (BUD) in sustained release capsules and tablets: Results of a pharmacokinetic and -dynamic study in healthy volunteers
-
Tromm A. Möllmann HW. Barth J. et al. Multiple oral application of budesonide (BUD) in sustained release capsules and tablets: Results of a pharmacokinetic and -dynamic study in healthy volunteers. Gastroenterology 1994; 106: A784.
-
(1994)
Gastroenterology
, vol.106
-
-
Tromm, A.1
Möllmann, H.W.2
Barth, J.3
-
54
-
-
0000535525
-
Oral budesonide competes favorably with prednisolone in active Crohn's disease
-
Campieri M. Ferguson A. Doe W. Oral budesonide competes favorably with prednisolone in active Crohn's disease. Gastroenterology 1995; 108: A790.
-
(1995)
Gastroenterology
, vol.108
-
-
Campieri, M.1
Ferguson, A.2
Doe, W.3
-
55
-
-
1842553953
-
Oral budesonide as maintenance treatment for Crohn's disease
-
Greenberg GR, Feagan BG, Martin F, et al. Oral budesonide as maintenance treatment for Crohn's disease. Gastroenterology 1995; 108: A827.
-
(1995)
Gastroenterology
, vol.108
-
-
Greenberg, G.R.1
Feagan, B.G.2
Martin, F.3
-
56
-
-
0027259123
-
The oral systemic availability of flucticasone propionate in man - Preliminary data
-
Bye A. The oral systemic availability of flucticasone propionate in man - preliminary data. Br J Clin Pharmacol 1993; 36: 136-7.
-
(1993)
Br J Clin Pharmacol
, vol.36
, pp. 136-137
-
-
Bye, A.1
-
57
-
-
0025132348
-
The human pharmacology of fluticasone propionate
-
Harding SM. The human pharmacology of fluticasone propionate. Resp Med 1990; 84 (Suppl. A): 25-9.
-
(1990)
Resp Med
, vol.84
, Issue.SUPPL. A
, pp. 25-29
-
-
Harding, S.M.1
-
58
-
-
0030048729
-
Pharmacodynamics and pharmacokinetics of inhaled glucocorticoids
-
Johnson M. Pharmacodynamics and pharmacokinetics of inhaled glucocorticoids. J Allergy Clin Immunol 1996; 97: 169-76.
-
(1996)
J Allergy Clin Immunol
, vol.97
, pp. 169-176
-
-
Johnson, M.1
-
60
-
-
0027469243
-
Double blind trial of oral tluticasone versus prednisolone in the treatment of active ulcerative colitis
-
Hawthorne AB, Record CO. Holdsworth MH, et al. Double blind trial of oral tluticasone versus prednisolone in the treatment of active ulcerative colitis. Gut 1993; 34: 125-8.
-
(1993)
Gut
, vol.34
, pp. 125-128
-
-
Hawthorne, A.B.1
Record, C.O.2
Holdsworth, M.H.3
-
61
-
-
0026504164
-
Oral tluticasone propionate in active distal ulcerative colitis
-
Angus P, Snook JA, Reid MI, et al. Oral tluticasone propionate in active distal ulcerative colitis. Gut 1993; 33: 711-14.
-
(1993)
Gut
, vol.33
, pp. 711-714
-
-
Angus, P.1
Snook, J.A.2
Reid, M.I.3
-
62
-
-
0029849213
-
Dynamic modeling of cortisol reduction after inhaled administration of fluticasone propionate
-
Rohatagi S, Bye A, Falcoz C, et al. Dynamic modeling of cortisol reduction after inhaled administration of fluticasone propionate. J Clin Pharmacol 1996; 36: 938-41.
-
(1996)
J Clin Pharmacol
, vol.36
, pp. 938-941
-
-
Rohatagi, S.1
Bye, A.2
Falcoz, C.3
-
63
-
-
0028117637
-
The in vivo behaviour of a colonic delivery system: A pilot study in man
-
Steed KP, Hooper G, Ventura P, et al. The in vivo behaviour of a colonic delivery system: a pilot study in man. Int J Pharm 1994; 112: 199-206.
-
(1994)
Int J Pharm
, vol.112
, pp. 199-206
-
-
Steed, K.P.1
Hooper, G.2
Ventura, P.3
-
64
-
-
0023693299
-
Measurement of gastrointestinal pH profiles in normal ambulant human subjects
-
Evans DF, Pye G, Bramley R, et al. Measurement of gastrointestinal pH profiles in normal ambulant human subjects. Gut 1988; 29: 1035-41.
-
(1988)
Gut
, vol.29
, pp. 1035-1041
-
-
Evans, D.F.1
Pye, G.2
Bramley, R.3
-
66
-
-
0027490263
-
Very low intraluminal colonic pH in patients with active ulcerative colitis
-
Fallingborg J. Christensen LA. Ascanius B. et al. Very low intraluminal colonic pH in patients with active ulcerative colitis. Dig Dis Sci 1993; 38: 1989-93.
-
(1993)
Dig Dis Sci
, vol.38
, pp. 1989-1993
-
-
Fallingborg, J.1
Christensen, L.A.2
Ascanius, B.3
-
67
-
-
0031032409
-
Improved localizing method of radiopill in measurement of entire gastrointestinal pH profiles: Colonic luminal pH in normal subjects and patients with Crohn's disease
-
Sasaki Y, Hada R, Nakajima H, et al. Improved localizing method of radiopill in measurement of entire gastrointestinal pH profiles: Colonic luminal pH in normal subjects and patients with Crohn's disease. Am J Gastroenterol 1997; 92: 114-18.
-
(1997)
Am J Gastroenterol
, vol.92
, pp. 114-118
-
-
Sasaki, Y.1
Hada, R.2
Nakajima, H.3
-
68
-
-
0027157424
-
An in vitro investigation into the suitability of pH-dependent polymers for colon targeting
-
Ashford M. Fell JT. Attwood D. et al. An in vitro investigation into the suitability of pH-dependent polymers for colon targeting. Int J Pharm 1993; 91: 241-5.
-
(1993)
Int J Pharm
, vol.91
, pp. 241-245
-
-
Ashford, M.1
Fell, J.T.2
Attwood, D.3
-
69
-
-
0027254453
-
An in vivo investigation into the suitability of pH dependent polymers for colonic targeting
-
Ashford A. Fell AT. Attwood D. et al. An in vivo investigation into the suitability of pH dependent polymers for colonic targeting. Int J Pharm 1993; 95: 193-9.
-
(1993)
Int J Pharm
, vol.95
, pp. 193-199
-
-
Ashford, A.1
Fell, A.T.2
Attwood, D.3
-
70
-
-
0007883915
-
Gastrointestinal-physiological variables affecting the performance of oral sustained release dosage forms
-
Yacobi A. Halperin-Walega E, eds. New York: Pergamon Press
-
Rubinstein A, Li VHK, Gruber P, et al. Gastrointestinal-physiological variables affecting the performance of oral sustained release dosage forms. In: Yacobi A. Halperin-Walega E, eds. Oral Sustained Release Formulations: Design and Evaluation. New York: Pergamon Press. 1988; 125-56.
-
(1988)
Oral Sustained Release Formulations: Design and Evaluation
, pp. 125-156
-
-
Rubinstein, A.1
Li, V.H.K.2
Gruber, P.3
-
71
-
-
0025824433
-
Correlation of the gastric emptying of nondisintegrating tablets with gastrointestinal motility
-
Coupe AJ, Davis SS, Evans DF, et al. Correlation of the gastric emptying of nondisintegrating tablets with gastrointestinal motility. Pharm Res 1991; 8: 1281-85.
-
(1991)
Pharm Res
, vol.8
, pp. 1281-1285
-
-
Coupe, A.J.1
Davis, S.S.2
Evans, D.F.3
-
72
-
-
0022538998
-
Transit of pharmaceutical dosage forms through the small intestine
-
Davis SS. Hardy J. Fara JW Transit of pharmaceutical dosage forms through the small intestine. Gut 1986; 27: 886-92.
-
(1986)
Gut
, vol.27
, pp. 886-892
-
-
Davis, S.S.1
Hardy, J.2
Fara, J.W.3
-
73
-
-
0024949034
-
pH-profile and regional transit times of the normal gut measured by a radiotelemetry device
-
Fallingborg J. Christensen LA. Ingeman-Nielsen M. et al. pH-profile and regional transit times of the normal gut measured by a radiotelemetry device. Aliment Pharmacol Ther 1989; 5: 605-13.
-
(1989)
Aliment Pharmacol Ther
, vol.5
, pp. 605-613
-
-
Fallingborg, J.1
Christensen, L.A.2
Ingeman-Nielsen, M.3
-
74
-
-
0022971457
-
The effect of density on gastric emptying of single and multiple unit dosage forms
-
Davis SS. Stockwell MJ. Taylor MJ. et al. The effect of density on gastric emptying of single and multiple unit dosage forms. Pharm Res 1986; 3: 208-13.
-
(1986)
Pharm Res
, vol.3
, pp. 208-213
-
-
Davis, S.S.1
Stockwell, M.J.2
Taylor, M.J.3
-
75
-
-
0001593487
-
Gastrointestinal transit of nondisintegrating tablets in fed subjects
-
Khosla R. Feely LC. Davis SS. Gastrointestinal transit of nondisintegrating tablets in fed subjects. Int J Pharm 1989; 53: 107-17.
-
(1989)
Int J Pharm
, vol.53
, pp. 107-117
-
-
Khosla, R.1
Feely, L.C.2
Davis, S.S.3
-
76
-
-
0025955683
-
Scintigraphic and pharmacokinelic assessment of a multiparticulate sustained release formulation of diltiazem
-
Wilding IR. Hardy JG. Maccari M. et al. Scintigraphic and pharmacokinelic assessment of a multiparticulate sustained release formulation of diltiazem. Int J Pharm 1991; 76: 133-43.
-
(1991)
Int J Pharm
, vol.76
, pp. 133-143
-
-
Wilding, I.R.1
Hardy, J.G.2
Maccari, M.3
-
78
-
-
0027472867
-
Colonic transit of different size tablets in healthy subjects
-
Adkin DA. Davis SS. Sparrow RA. et al. Colonic transit of different size tablets in healthy subjects. J Controlled Rel 1993; 23: 147-56.
-
(1993)
J Controlled Rel
, vol.23
, pp. 147-156
-
-
Adkin, D.A.1
Davis, S.S.2
Sparrow, R.A.3
-
79
-
-
0024424730
-
Human gastric emptying and colonic filling of solids characterized by a new method
-
Camilleri M. Colemont LJ. Phillips SF. et al. Human gastric emptying and colonic filling of solids characterized by a new method. Am J Physiol 1989; 257: G284-90.
-
(1989)
Am J Physiol
, vol.257
-
-
Camilleri, M.1
Colemont, L.J.2
Phillips, S.F.3
-
80
-
-
0022443728
-
Colonic transit scintigraphy. A physiologic approach to the quantitative measurement of colonic transit in humans
-
Krevsky B. Malmud LS. F. D'Ercole F. et al. Colonic transit scintigraphy. A physiologic approach to the quantitative measurement of colonic transit in humans. Gastroenterologv 1986; 91: 1102-12.
-
(1986)
Gastroenterologv
, vol.91
, pp. 1102-1112
-
-
Krevsky, B.1
Malmud, L.S.2
F. D'Ercole, F.3
-
81
-
-
0025350430
-
Transit of solids through the human colon: Regional quantification in the unprepared bowel
-
Proano M. Camilleri M. Phillips SF. et al. Transit of solids through the human colon: regional quantification in the unprepared bowel. Am J Physiol 1990; 258: G856-62.
-
(1990)
Am J Physiol
, vol.258
-
-
Proano, M.1
Camilleri, M.2
Phillips, S.F.3
-
82
-
-
0021216921
-
The in vivo evaluation of an osmotic device (Osmet) using gamma scintigraphy
-
Davis SS, Hardy JG, Taylor MJ. et al. The in vivo evaluation of an osmotic device (Osmet) using gamma scintigraphy. J Pharm Pharmacol 1984; 36: 740-2.
-
(1984)
J Pharm Pharmacol
, vol.36
, pp. 740-742
-
-
Davis, S.S.1
Hardy, J.G.2
Taylor, M.J.3
-
83
-
-
0021205310
-
A comparative study of the gastrointestinal transit of a pellet and tablet formulalion
-
Davis SS. Hardy JG, Taylor MJ. et al. A comparative study of the gastrointestinal transit of a pellet and tablet formulalion. Int J Pharm 1984; 21: 167-77.
-
(1984)
Int J Pharm
, vol.21
, pp. 167-177
-
-
Davis, S.S.1
Hardy, J.G.2
Taylor, M.J.3
-
86
-
-
0000543508
-
The intestinal transit of capsules and pellets
-
Hardy JG. Wood E, Wilson CG. The intestinal transit of capsules and pellets. Dig Dis Sci 1985; 30: 772.
-
(1985)
Dig Dis Sci
, vol.30
, pp. 772
-
-
Hardy, J.G.1
Wood, E.2
Wilson, C.G.3
-
87
-
-
0016422829
-
Medical and dietary management
-
Eastwood MA. Medical and dietary management. Clinics Gastroenterol 1975; 4: 85-97.
-
(1975)
Clinics Gastroenterol
, vol.4
, pp. 85-97
-
-
Eastwood, M.A.1
-
88
-
-
0001863361
-
Pathophysiology of symptoms and clinical features of inflammatory bowel disease
-
Kirshner JB. Shorter RG. eds. Baltimore: Williams and Wilkens
-
Sandborn WJ. Philips SF. Pathophysiology of symptoms and clinical features of inflammatory bowel disease. In: Kirshner JB. Shorter RG. eds. Inflammatory Bowel Disease (4th edn). Baltimore: Williams and Wilkens, 1995; 407-36.
-
(1995)
Inflammatory Bowel Disease (4th Edn).
, pp. 407-436
-
-
Sandborn, W.J.1
Philips, S.F.2
-
89
-
-
0000614893
-
Serum electrolytes and colonic transfer of water and electrolytes in chronic ulcerative colitis
-
Duthie HL. Watts JM. Dedombal FT. et al. Serum electrolytes and colonic transfer of water and electrolytes in chronic ulcerative colitis. Gastroenterology 1964; 47: 525.
-
(1964)
Gastroenterology
, vol.47
, pp. 525
-
-
Duthie, H.L.1
Watts, J.M.2
Dedombal, F.T.3
-
90
-
-
0023514333
-
Studies on the mechanism of bowel disturbance in ulcerative colitis
-
Rao SSC. Read MW. Brown C, et al. Studies on the mechanism of bowel disturbance in ulcerative colitis. Gastroenterology 1987; 93: 934-40.
-
(1987)
Gastroenterology
, vol.93
, pp. 934-940
-
-
Rao, S.S.C.1
Read, M.W.2
Brown, C.3
-
91
-
-
0018078245
-
Some parameters of large bowel motility in normal man
-
Martelli H. Devroede G. Arhan P. et al. Some parameters of large bowel motility in normal man. Gastroenterology 1978; 75: 612-18.
-
(1978)
Gastroenterology
, vol.75
, pp. 612-618
-
-
Martelli, H.1
Devroede, G.2
Arhan, P.3
-
92
-
-
0026032218
-
Gastrointestinal transit of a multiparticulate tablet formulation in patients with active ulcerative colitis
-
Davis SS. Robertson C. Wilding IR. Gastrointestinal transit of a multiparticulate tablet formulation in patients with active ulcerative colitis. Int J Pharm 1991; 68: 199-204.
-
(1991)
Int J Pharm
, vol.68
, pp. 199-204
-
-
Davis, S.S.1
Robertson, C.2
Wilding, I.R.3
-
93
-
-
0023931794
-
Symptoms and stool patterns in patients with ulcerative colitis
-
Rao SSC, Holdsworth CD. Read NW. Symptoms and stool patterns in patients with ulcerative colitis. Gut 1988; 29: 342-5.
-
(1988)
Gut
, vol.29
, pp. 342-345
-
-
Rao, S.S.C.1
Holdsworth, C.D.2
Read, N.W.3
-
95
-
-
0025939784
-
The assessment of faecal flora with inflammatory bowel disease by a simplified bacteriological technique
-
Giaffer MH, Holdsworth CD. Duerden BI. The assessment of faecal flora with inflammatory bowel disease by a simplified bacteriological technique. J Med Microbiol 1991; 35: 238-43.
-
(1991)
J Med Microbiol
, vol.35
, pp. 238-243
-
-
Giaffer, M.H.1
Holdsworth, C.D.2
Duerden, B.I.3
-
96
-
-
0345101888
-
Role of intestinal microflora in ulcerative colitis
-
Henteges DJ. ed. New York: Academic Press
-
Onderdonk AB. Role of intestinal microflora in ulcerative colitis. In: Henteges DJ. ed. Human Intestinal Microflora in Health and Disease. New York: Academic Press, 1983: 481-93.
-
(1983)
Human Intestinal Microflora in Health and Disease
, pp. 481-493
-
-
Onderdonk, A.B.1
-
97
-
-
0026585423
-
The rectal mucosa-associated microflora in patients with ulcerative colitis
-
Gillian Hartley, Hudson MJ. Swarbrick ET. et al. The rectal mucosa-associated microflora in patients with ulcerative colitis. J Med Microbiol 1992; 36: 96-103.
-
(1992)
J Med Microbiol
, vol.36
, pp. 96-103
-
-
Hartley, G.1
Hudson, M.J.2
Swarbrick, E.T.3
-
98
-
-
0025953875
-
Growth and activities of sulphate-reducing bacteria in gut contents of healthy subjects and patients with ulcerative colitis
-
Gibson GR, Cummings JH, Macfarlane GT. Growth and activities of sulphate-reducing bacteria in gut contents of healthy subjects and patients with ulcerative colitis. FEMS Microbiol Ecol 1991; 86: 103-12.
-
(1991)
FEMS Microbiol Ecol
, vol.86
, pp. 103-112
-
-
Gibson, G.R.1
Cummings, J.H.2
Macfarlane, G.T.3
-
99
-
-
0027178903
-
Functional alterations of the microflora in patients with ulcerative colitis
-
Benno P. Leijonmarck C-E. Monsen U. et al. Functional alterations of the microflora in patients with ulcerative colitis. Scand J Gastroenterol 1993; 28: 839-44.
-
(1993)
Scand J Gastroenterol
, vol.28
, pp. 839-844
-
-
Benno, P.1
Leijonmarck, C.-E.2
Monsen, U.3
-
101
-
-
0014139660
-
A quantitative comparison of the faecal Ilora of patients with ulcerative colitis and that of normal persons
-
Cooke EM. A quantitative comparison of the faecal Ilora of patients with ulcerative colitis and that of normal persons. J Path Bact 1967; 9: 439-44.
-
(1967)
J Path Bact
, vol.9
, pp. 439-444
-
-
Cooke, E.M.1
-
102
-
-
0014274253
-
Studies of intestinal microllora V. Fecal microbial ecology in ulcerative colitis and regional enteritis: Relationship to severity of disease and chemotherapy
-
Gorbach SL. Nahas L. Plaut AG, et al. Studies of intestinal microllora V. Fecal microbial ecology in ulcerative colitis and regional enteritis: relationship to severity of disease and chemotherapy. Gastroenterology 1968; 54: 575-87.
-
(1968)
Gastroenterology
, vol.54
, pp. 575-587
-
-
Gorbach, S.L.1
Nahas, L.2
Plaut, A.G.3
-
103
-
-
0020960851
-
Anaerobic Gram-negative faecal flora in patients with Crohn's disease and healthy subjects
-
Ruseler-van Embden JGH, Both-Patoir HC. Anaerobic Gram-negative faecal flora in patients with Crohn's disease and healthy subjects. Ant Leeuwen 1983; 49: 125-32.
-
(1983)
Ant Leeuwen
, vol.49
, pp. 125-132
-
-
Ruseler-van Embden, J.G.H.1
Both-Patoir, H.C.2
-
105
-
-
0018222160
-
Influence of inflammatory bowel disease on intestinal microflora
-
Keighley MRB. Arabi Y. Dimock F. et al. Influence of inflammatory bowel disease on intestinal microflora. Gut 1978; 19: 1099-104.
-
(1978)
Gut
, vol.19
, pp. 1099-1104
-
-
Keighley, M.R.B.1
Arabi, Y.2
Dimock, F.3
-
106
-
-
0023234298
-
Increased fecal glycosidases on patients with Crohn's disease
-
Ruseler-van Embden JGH. Van Lieshout LMC. Increased fecal glycosidases on patients with Crohn's disease. Digestion 1987; 37: 43-50.
-
(1987)
Digestion
, vol.37
, pp. 43-50
-
-
Ruseler-van Embden, J.G.H.1
Van Lieshout, L.M.C.2
-
107
-
-
0026702404
-
Decreased fecal exoglycosidase activities identify a subset of patients with active Crohn's disease
-
El Yamni J. Mizon C. Capon C. et al. Decreased fecal exoglycosidase activities identify a subset of patients with active Crohn's disease. Clin Sci 1992; 83: 409-15.
-
(1992)
Clin Sci
, vol.83
, pp. 409-415
-
-
El Yamni, J.1
Mizon, C.2
Capon, C.3
-
108
-
-
0027720205
-
L'activite beta-galactosidascique fecale est diminuce as cours de la maladie de Crohn
-
Canva-Delcambre V. Soenen V. Mizon A. et al. L'activite beta-galactosidascique fecale est diminuce as cours de la maladie de Crohn. Gastroenterol Clin Biol 1993; 17: 718-22.
-
(1993)
Gastroenterol Clin Biol
, vol.17
, pp. 718-722
-
-
Canva-Delcambre, V.1
Soenen, V.2
Mizon, A.3
-
109
-
-
0021810593
-
Faecal mucus degrading glycosidases in ulcerative colitis and Crohn's disease
-
Rhodes JM. Gallimore R. Elias E. et al. Faecal mucus degrading glycosidases in ulcerative colitis and Crohn's disease. Gut 1985; 26: 761-5.
-
(1985)
Gut
, vol.26
, pp. 761-765
-
-
Rhodes, J.M.1
Gallimore, R.2
Elias, E.3
-
110
-
-
0029610175
-
Bacterial enzymes used for colon-specific drug delivery are decreased in active Crohn's disease
-
Carrette O, Favier C, Mizon C. et al. Bacterial enzymes used for colon-specific drug delivery are decreased in active Crohn's disease. Dig Dis Sci 1995; 40: 2641-46.
-
(1995)
Dig Dis Sci
, vol.40
, pp. 2641-2646
-
-
Carrette, O.1
Favier, C.2
Mizon, C.3
-
111
-
-
0028906632
-
Estimation of agitation intensity in the G1 tract in humans and dogs based on in vitro/in vivo correlation
-
Katori N. Aoyagi N. Terao T. Estimation of agitation intensity in the G1 tract in humans and dogs based on in vitro/in vivo correlation. Pharm Res 1995; 12: 237-43.
-
(1995)
Pharm Res
, vol.12
, pp. 237-243
-
-
Katori, N.1
Aoyagi, N.2
Terao, T.3
-
112
-
-
0029019419
-
Oral solid controlled release dosage forms role of G1-mechanical destructive forces and colonic release in drug absorption under fasted and fed conditions in humans
-
Shameen M. Katori N. Aoyagi N. et al. Oral solid controlled release dosage forms role of G1-mechanical destructive forces and colonic release in drug absorption under fasted and fed conditions in humans. Pharm Res 1995; 12: 1049-54.
-
(1995)
Pharm Res
, vol.12
, pp. 1049-1054
-
-
Shameen, M.1
Katori, N.2
Aoyagi, N.3
-
113
-
-
0030796952
-
Gastrointestinal drug absorption: Is it time to consider herterogeniety as well as homogeniety
-
Macheras P. Argyrakis P. Gastrointestinal drug absorption: Is it time to consider herterogeniety as well as homogeniety. Pharm Res 1997; 14: 842-7.
-
(1997)
Pharm Res
, vol.14
, pp. 842-847
-
-
Macheras, P.1
Argyrakis, P.2
-
114
-
-
0000395880
-
Fractal growth of viscous fingers: Quantitative characterization of fluid instability phenomenon
-
Nittmann J. Daccord G. Stanley HE. Fractal growth of viscous fingers: quantitative characterization of fluid instability phenomenon. Nature 1985; 314: 141-4.
-
(1985)
Nature
, vol.314
, pp. 141-144
-
-
Nittmann, J.1
Daccord, G.2
Stanley, H.E.3
-
115
-
-
0012061292
-
Flow and interfacial instabilities in Newtonian and colloidal fluids (or the birth, life, and death of a fractal)
-
Avnir D. ed. Chichester: John Wiley
-
Van Damme H. Flow and interfacial instabilities in Newtonian and colloidal fluids (or the birth, life, and death of a fractal). In: Avnir D. ed. The Fractal Approach to Heterogeneous Chemistry. Chichester: John Wiley. 1989: 199-226.
-
(1989)
The Fractal Approach to Heterogeneous Chemistry
, pp. 199-226
-
-
Van Damme, H.1
-
116
-
-
10144222125
-
Correlation between kinetic properties and clinical safety of budesonide enema
-
abstract no. PD 561 Syndey, Australia
-
Edsbacker S. Johansson SA. Correlation between kinetic properties and clinical safety of budesonide enema (abstract no. PD 561). World Congress Gastroenterology. Syndey, Australia. 1990.
-
(1990)
World Congress Gastroenterology
-
-
Edsbacker, S.1
Johansson, S.A.2
-
117
-
-
84990159211
-
Rectal and oral bioavailability of budesonide in man
-
abstract no. 297
-
Dahlstrom K. Edsbacker S, Conradson T-B. Rectal and oral bioavailability of budesonide in man [abstract no. 297]. Hell J Gastroenterol 1992; 5 (Suppl.).
-
(1992)
Hell J Gastroenterol
, vol.5
, Issue.SUPPL.
-
-
Dahlstrom, K.1
Edsbacker, S.2
Conradson, T.-B.3
-
118
-
-
0027182016
-
Pharmacokinetics of budesonide enema in patients with distal ulcerative colitis or proctitis
-
Danielsson A, Edsbacker S. Lofberg R. et al. Pharmacokinetics of budesonide enema in patients with distal ulcerative colitis or proctitis. Alimment Pharmacol Ther 1993; 7: 401-7.
-
(1993)
Alimment Pharmacol Ther
, vol.7
, pp. 401-407
-
-
Danielsson, A.1
Edsbacker, S.2
Lofberg, R.3
-
119
-
-
0001048599
-
Dose-porportional kinetics of budesonide controlled ileal release capsules
-
Nilsson M. Edsbacker S, Larsson P. et al. Dose-porportional kinetics of budesonide controlled ileal release capsules [abstract]. Gastroenterology 1995; 108: A885.
-
(1995)
Gastroenterology
, vol.108
-
-
Nilsson, M.1
Edsbacker, S.2
Larsson, P.3
|