Protective effect of Copaifera langsdorffii oleo-resin against acetic acid-induced colitis in rats

Journal of Ethnopharmacology

Volumn 93, Issue 1, 2004, Pages 51-56

  Paiva, L A F ^a   Gurgel, L A ^a   De Sousa, E T ^a   Silveira, E R ^a   Silva, R M ^a   Santos, F A ^a   Rao, V S N ^a  

^a FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

Author keywords

Acetic acid; Antioxidant; Colitis; Copaiba oleo resin; Mucosal damage

Indexed keywords

ACETIC ACID; ANTIOXIDANT; COPAIFERA LANGSDORFFII EXTRACT; MALONALDEHYDE; MYELOPEROXIDASE; PLANT RESIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL INFILTRATION; CHEMICAL ANALYSIS; COLITIS; COLON INJURY; COLON MUCOSA; CONTROLLED STUDY; COPAIFERA LANGSDORFFII; DISEASE SEVERITY; DRUG ACTIVITY; DRUG MECHANISM; DRUG SCREENING; ENZYME ACTIVITY; INFLAMMATORY CELL; LIPID PEROXIDATION; MALE; MEDICINAL PLANT; NEUTROPHIL CHEMOTAXIS; NONHUMAN; RAT;

ACETIC ACID; ANIMALS; BALSAMS; COLITIS; FABACEAE; MALE; PLANT BARK; PLANT EXTRACTS; RATS; RATS, WISTAR;

EID: 2942587235     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2004.03.028     Document Type: Article

References (28)

1. Baker S., Campbell L. Rat enterocyte injury: oxygen-dependent processes. Gastroenterology. 101:1991;716-720
2. Bradley P.P., Christensen R.D., Rothstein G. Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. Journal of Investigational Dermatology. 78:1982;206-209
3. Braga, R., 1953. Plantas do Nordeste, Especialmente do Ceará. Centro de Divulgação Universitária, Imprensa Oficial, Fortaleza, p. 391.
4. Buell M., Berin C. Neutrophil-independence of colonic injury. Comparison of results from three models of experimental colitis in the rat. Digestive Diseases and Sciences. 39:1994;2575-2588
5. Carty E., De Brabander M., Feakins R.M., Rampton D.S. Measurement of in vivo rectal mucosal cytokine and eicosanoid production in ulcerative colitis using filter paper. Gut. 46:2000;487-492
6. Castrillo A., de Las Heras B., Hortelano S., Rodriguez B., Villar A., Bosca L. Inhibition of the nuclear factor kappa B (NF-kappa B) pathway by tetracyclic kaurene diterpenes in macrophages. Specific effects on NF-kappa B-inducing kinase activity and on the coordenate activation of ERK and p38 MAPK. Journal of Biological Chemistry. 276:2001;15854-15860
7. Costa-Lotufo L.V., Cunha G.M.A., Farias P.A.M., Viana G.S.B., Cunha K.M.A., Pessoa C., Moraes M.O., Silveira E.R., Gramosa N.V., Rao V.S.N. The cytotoxic and embryotoxic effects of kaurenoic acid, a diterpene isolated from Copaifera langsdorffii oleo-resin. Toxicon. 40:2002;1231-1234
8. De Alencar Cunha, K.M., Paiva, L.A.F., Santos, F.A., Gramosa, N.V., Silveira, E.R., Rao, V.S.N., 2003. Smooth muscle relaxant effect of kaurenoic acid, a diterpene from Copaifera langsdorffii on rat uterus in vitro. Phytotherapy Research 17, 320-324.
9. Fernandes R.M., Pereira N.A., Paulo L.G. Anti-inflammatory activity of copaíba balsam (Copaifera cearensis, Huber). Revista Brasileira de Farmacia. 73:1992;53-56
10. Gramosa, N.V., Brigido, C.L., Silveira, E.R., 1996. Contribuiç ão ao conhecimento químico do óleo de Copaíba do Ceará. VII Encontro de Químicos e Farmacêuticos Industriais do Norte-Nordeste, Fortaleza-CE, 5 a 8 de Novembro.
11. Kettle A.J., Gedye C.A., Winterbourn C.C. Mechanism of inactivation of myeloperoxidase by 4-aminobenzoic acid hydrochloride. Biochemistry Journal. 321:1997;503-508
12. Krawisz J.E., Sharon P., Stenson W.F. Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Gastroenterology. 87:1984;1344-1350
13. Kruidenier L., Verspaget H.W. Antioxidants and mucosa protectives: realistic therapeutic options in inflammatory bowel disease? Mediators of Inflammation. 7:1998;157-162
14. Loguercio C., D'Argenio G., Delle Cave M., Cosenza V., Della Valle N., Mazzcca Blanco C.V. Direct evidence of oxidative damage in acute and chronic phases of experimental colitis in rats. Digestive Diseases and Sciences. 41:1996;1204-1211
15. MacPherson B., Pfeiffer C. Experimental production of diffuse colitis in rats. Digestion. 17:1978;135-150
16. Mascolo N., Izzo A., Autore G., Maiello F., Di Carlo G., Capasso F. Acetic acid-induced colitis in normal and essential fatty acid deficient rats. Journal of Pharmacology and Experimental Therapeutics. 272:1995;469-475
17. Noa M., Más R., Carbajal D., Valdés S. Effect of D-002 on acetic acid-induced colitis in rats at single and repeated doses. Pharmacological Research. 41:2000;391-395
18. Ohkawa H., Ohishi N., Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Annals of Biochemistry. 95:1979;351-358
19. Paiva L.A.F., Rao V.S.N., Gramosa N.V., Silveira E.R. Gastroprotective effect of Copaifera langsdorffii oil-resin on experimental gastric ulcer models in rats. Ethnopharmacology. 62:1998;73-78
20. Paiva, L.A.F., De Alencar Cunha, K.M., Santos, F.A., Gramosa, N.V., Silveira, E.R, Rao, V.S.N., 2002. Investigation on the wound healing activity of óleo-resin from Copaifera langsdorffii in rats. Phytotherapy Research 16, 737-739.
21. Pio Corrêa, M., 1984. Dicionário das Plantas Úteis do Brasil e das Exóticas Cultivadas, vol. 2. Imprensa Nacional, Rio de Janeiro, pp. 370-375.
22. Rachmilewitz D., Simon P.L., Schwartz L.W., Griswald D.E., Fondacaro J.D., Wasserman M.A. Inflammatory mediators of experimental colitis in rats. Gastroenterology. 97:1989;326-327
23. Salim A.S. Role of oxygen-derived free radical scavengers in the management of recurrent attacks of ulcerative colitis: a new approach. Journal of Laboratory and Clinical Medicine. 119:1992;710-717
24. Seo H.G., Takata L., Nakamura M., Tatsumi H., Fujii J., Taniguchi N. Induction of nitric oxide synthase and concomitant suppression of superoxide dismutases in experimental colitis in rats. Archives of Biochemistry and Biophysics. 324:1995;41-47
25. Sharon P., Stenson W.F. Metabolism of arachidonic acid in acetic acid colitis in rats: similarity to human inflammatory bowel disease. Gastroenterology. 88:1985;55-63
26. Uchiyama M., Mihara M. Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Analytical Biochemistry. 86:1978;271-278
27. Velikova M., Bankova V., Tsvetkova I., Kujumgiev A., Marcucci M.C. Antibacterial ent-kaurene from Brazilian propolis of native stingles bees. Fitoterapia. 71:2000;693-696
28. Veljaca M., Lesch C.A., Pllana R., Sanchez B., Chan K., Guglietta A.J. BPC-15 reduces trinitrobenzene sulfonic acid-induced colonic damage in rats. Journal of Pharmacology and Experimental Therapeutics. 272:1995;417-422