Increased levels of oxidants and reduced antioxidants in semen of infertile men with varicocele

Fertility and Sterility

Volumn 94, Issue 4, 2010, Pages 1531-1534

  Abd Elmoaty, Mohamed Ahmed ^a   Saleh, Ramadan ^a   Sharma, Rakesh ^b   Agarwal, Ashok ^b  

^a Sohag University   (Egypt)

^b LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID; CATALASE; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; NITRIC OXIDE; SUPEROXIDE DISMUTASE; ANTIOXIDANT; OXIDIZING AGENT;

ARTICLE; CONTROLLED STUDY; HUMAN; MALE; MALE INFERTILITY; OXIDATIVE STRESS; PRIORITY JOURNAL; SEMEN ANALYSIS; SPERM; SPERMATOZOON DENSITY; SPERMATOZOON MOTILITY; VARICOCELE; CASE CONTROL STUDY; COMPLICATION; INFERTILITY, MALE; METABOLISM; UPREGULATION;

ANTIOXIDANTS; ASCORBIC ACID; CASE-CONTROL STUDIES; CATALASE; GLUTATHIONE PEROXIDASE; HUMANS; INFERTILITY, MALE; MALE; MALONDIALDEHYDE; NITRIC OXIDE; OXIDANTS; SEMEN; SEMEN ANALYSIS; SUPEROXIDE DISMUTASE; UP-REGULATION; VARICOCELE;

EID: 77956189400     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2009.12.039     Document Type: Article

References (39)

1. C.K. Naughton, A.K. Nangia, and A. Agarwal Varicocele and male infertility: part II. Pathophysiology of varicoceles in male infertility Hum Reprod Update 7 2001 473 481
2. T. Mostafa, T.H. Anis, S. Ghazi, A.R. El-Nashar, H. Imam, and I.A. Osman Reactive oxygen species and antioxidants relationship in the internal spermatic vein blood of infertile men with varicocele Asian J Androl 8 2006 451 454
3. T. Mostafa, T. Anis, H. Imam, A.R. El-Nashar, and I.A. Osman Seminal reactive oxygen species-antioxidant relationship in fertile males with and without varicoceles Andrologia 41 2009 125 129
4. B. Hendin, P. Kolettis, R.K. Sharma, A.J. Thomas Jr., and A. Agarwal Varicocele is associated with elevated spermatozoal reactive oxygen species production and diminished seminal plasma antioxidant capacity J Urol 161 1999 1831 1834
5. S.S. Chen, L.S. Chang, and Y.H. Wei Oxidative damage to proteins and decrease of antioxidant capacity in patients with varicocele Free Radic Biol Med 30 2001 1328 1334
6. E.R. Barbieri, M.E. Hidalgo, A. Venegas, R. Simth, and E.A. Lissi Varicocele-associated decrease in antioxidant defenses J Androl 20 1999 713 717
7. A. Agarwal, R.K. Sharma, N.R. Desai, S. Prabakaran, A. Tavares, and E. Sabanegh Role of oxidative stress in pathogenesis of varicocele and infertility Urology 73 2009 461 469
8. R.K. Sharma, and A. Agarwal Role of reactive oxygen species in male infertility Urology 48 1996 835 850
9. A. Agarwal, K. Makker, and R. Sharma Clinical relevance of oxidative stress in male factor infertility: an update Am J Reprod Immunol 59 2008 2 11
10. M.G. Davies, G.J. Fulton, and P.O. Hagen Clinical biology of nitric oxide Br J Surg 82 1995 1598 1610
11. A. Zini, M.K. O'Bryan, and P.N. Schlegel Nitric oxide synthase activity in human seminal plasma Urology 58 2001 85 89
12. M.B. Herrero, E. de Lamirande, and C. Gagnon Tyrosine nitration in human spermatozoa: a physiological function of peroxynitrite, the reaction product of nitric oxide and superoxide Mol Hum Reprod 7 2001 913 921
13. M. Rosselli, R.K. Dubey, B. Imthurn, E. Macas, and P.J. Keller Effects of nitric oxide on human spermatozoa: evidence that nitric oxide decreases sperm motility and induces sperm toxicity Hum Reprod 10 1995 1786 1790
14. J.B. Weinberg, E. Doty, J. Bonaventure, and A.F. Haney Nitric oxide inhibition of human sperm motility Fertil Steril 64 1995 408 413
15. D. Mitropoulos, G. Deliconstantinous, A. Zervas, V. Villiotou, C. Dimopoulos, and J. Stavrides Nitric oxide synthase and xanthine oxidase activities in the spermatic vein of patients with varicocele: a potential role for nitric oxide and peroxynitrite in sperm dysfunction J Urol 156 1996 1952 1958
16. E. Ozbek, Y. Turkoz, R. Gokdeniz, M. Davarci, and F. Ozugurlu Increased nitric oxide production in the spermatic vein of patients with varicocele Eur Urol 37 2000 172 175
17. G. Balercia, S. Moretti, A. Vignini, M. Magagnini, F. Mantero, and M. Boscaro Role of nitric oxide concentrations on human sperm motility J Androl 25 2004 245 249
18. A. Vignini, L. Nanetti, E. Buldreghini, C. Moroni, and G. Ricciardo-Lamonica The production of peroxynitrite by human spermatozoa may affect sperm motility through the formation of protein nitrotyrosine Fertil Steril 85 2006 947 953
19. World Health Organization World Health Organization laboratory manual for the examination of human semen and sperm-cervical mucus interaction 4th ed. 1999 Cambridge University Press Cambridge, U.K
20. J. Buege, and S. Aust Microsomal lipid peroxidation Meth Enzymol 52 1978 302 310
21. T.E. Weichselbaum An accurate and rapid method for the determination of proteins in small amounts of blood serum and plasma Am J Clin Pathol 10 1946 40 48
22. A. Kyaw A simple colorimetric method for ascorbic acid determination in blood plasma Clin Chim Acta 86 1978 153 157
23. R. Beers, and I. Sizer A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase J Biol Chem 195 1952 133
24. M.B. Grisham, and J.M. McCord Chemistry and cytotoxicity of reactive oxygen metabolites A.E. Taylor, S. Matalon, P. Ward, Biology of oxygen radicals 1986 American Physiological Society Bethesda, MD 1 18
25. H. Misra, and I. Fridovich The role of superoxide anion in the autooxidation of epinephrine and a simple assay for superoxide dismutase J Biol Chem 215 1972 3170
26. F.F. Pasqualotto, R.K. Sharma, D.R. Nelson, A.J. Thomas, and A. Agarwal Relationship between oxidative stress, semen characteristics, and clinical diagnosis in men undergoing infertility investigation Fertil Steril 73 2000 459 464
27. F.F. Pasqualotto, A. Sundaram, R.K. Sharma, E. Borges Jr., E.B. Pasqualotto, and A. Agarwal Semen quality and oxidative stress scores in fertile and infertile patients with varicocele Fertil Steril 89 2008 602 607
28. I.T. Köksal, A. Tefekli, M. Usta, H. Erol, S. Abbasoglu, and A. Kadioglu The role of reactive oxygen species in testicular dysfunction associated with varicocele BJU Int 86 2000 549 552
29. S.S. Allamaneni, C.K. Naughton, R.K. Sharma, and A. Agarwal Increased seminal reactive oxygen species levels in patients with varicoceles correlate with varicocele grade but not with testis size Fertil Steril 82 2004 1684 1686
30. M. Cocuzza, K.S. Athayde, A. Agarwal, R. Pagani, S.C. Sikka, and A.M. Lucon Impact of clinical varicocele and testis size on seminal reactive oxygen species levels in a fertile population: a prospective controlled study Fertil Steril 90 2008 1103 1108
31. World Health Organization The influence of varicocele on parameters of infertility in a large group of men presenting to infertility clinic Fertil Steril 57 1992 1289 1293
32. C.A. Villanueva-Diaz, E.A. Vega-Hernandez, M.A. Diaz-Perez, M. Echavarria-Sanchez, F.J. Ortiz-Ibarra, and J.L. Arredondo-Garcia Sperm dysfunction in subfertile patients with varicocele and marginal semen analysis Andrologia 31 1999 263 267
33. J. Zargooshi Sperm count and sperm motility in incidental high-grade varicocele Fertil Steril 88 2007 1470 1473
34. M. Plante, E. De Lamirande, and C. Gagnon Reactive oxygen species released by activated neutrophils, but not by deficient spermatozoa, are sufficient to affect normal sperm motility Fertil Steril 62 1994 387 393
35. R.J. Aitken The Amoroso Lecture. The human spermatozoon - a cell in crisis? J. Reprod Fertil 115 1999 1 7
36. Y. Aksoy, I. Ozbey, H. Aksoy, Ö Polat, and F. Akcay Seminal plasma nitric oxide concentration in oligo- and/or asthenozoospermic subjects with/without varicocele Arch Androl 48 2002 181 185
37. C. Romeo, R. Ientile, P. Impellizzeri, N. Turiaco, M. Teletta, and P. Antonuccio Preliminary report on nitric oxide-mediated oxidative damage in adolescent varicocele Hum Reprod 18 2003 26 29
38. Z. Turkyilmaz, S. Gulen, K. Sonmez, R. Karabulut, S. Dincer, and A. Can Basaklar Increased nitric oxide is accompanied by lipid oxidation in adolescent varicocele Int J Androl 27 2004 183 187
39. T. Mostafa, T.H. Anis, A. El-Nashar, H. Imam, and I.A. Othman Varicocelectomy reduces reactive oxygen species levels and increases antioxidant activity of seminal plasma from infertile men with varicocele Int J Androl 24 2001 261 265