Nitric oxide synthase and xanthine oxidase activities in the spermatic vein of patients with varicocele: A potential role for nitric oxide and peroxynitrite in sperm dysfunction

Journal of Urology

Volumn 156, Issue 6, 1996, Pages 1952-1958

  Mitropoulos, D ^a   Deliconstantinos, G ^a   Zervas, A ^a   Villiotou, V ^a   Dimopoulos, C ^a   Stavrides, J ^a  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

nitric oxide; varicocele; veins; xanthine oxidase

Indexed keywords

NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PEROXYACETYLNITRATE; SUPEROXIDE; XANTHINE OXIDASE;

ARTICLE; ENZYME ACTIVITY; HUMAN; MALE; MALE INFERTILITY; OXIDATIVE STRESS; PRIORITY JOURNAL; SPERMATIC VEIN; SPERMATOZOON ABNORMALITY; VARICOCELE;

EID: 0029861353     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(01)65403-X     Document Type: Article

References (35)

1. Greenberg S.M. Varicocele and male infertility. Fertil. Steril. 28 1977 699
2. Cockett A.T.K. Urry R.L. Dougherty K.A. The varicocele and semen characteristics. J. Urol. 121 1979 435
3. Schlesinger M.H. Wilets I.F. Nagler H.M. Treatment outcome after varicocelectomy. A critical analysis. Urol. Clin. N. Amer. 21 1994 517
4. Chakraborty J. Hikim A.P. Jhunjhunwala J.S. Stagnation of blood in the microcirculatory vessels in the testes of men with varicocele. J. Androl. 6 1985 117
5. Cohen M.S. Plaine L. Brown J.S. The role of internal spermatic vein plasma catecholamine determination in subfertile men with varicoceles. Fertil. Steril. 26 1975 1243
6. Goldstein M. Eid J.-F. Elevation of intratesticular and scrotal temperature in men with varicocele J. Urol. 142 1989 743
7. Ross J.A. Watson N.E. Jr. Jarow J.P. The effect of varicoceles on testicular blood flow in man. Urology 44 1994 535
8. Swerdloff R.S. Walsh P.C. Pituitary and gonadal hormone in patients with varicocele. Fertil. Steril. 26 1975 1006
9. Plante M. de Lamirande E. Gagnon C. Reactive oxygen species released by activated neutrophils, but not by defficient spermatozoa, are sufficient to affect normal sperm motility. Fertil. Steril. 62 1994 387
10. Krausz C. Mills C. Rogers S. Tan S.L. Aitken R.J. Stimulation of oxidant generation by human sperm suspensions using phorbol esters and formyl peptides: relationships with motility and fertilization in vitro. Fertil. Steril. 62 1994 599
11. Jones R. Mann T. Sherins R.J. Peroxidative breakdown of phospholipids in human spermatozoa, spermicidal properties of fatty acid peroxides, and protective action of seminal plasma. Fertil. Steril. 31 1979 531
12. Aitken R.J. Irvine D.S. Wu F.C. Prospective analysis of sperm-oocyte fusion and reactive oxygen species generation as criteria for the diagnosis of infertility. Amer. J. Obst. Gynec. 164 1991 542
13. Kessopoulou E. Tomlinson M.J. Barratt C.L.R. Bolton A.E. Cooke I.D. Origin of reactive oxygen species in semen; spermatozoa or leukocytes? J. Reprod. Fertil. 94 1992 463
14. Alvarez J.G. Touchstone J.C. Blasco L. Storey B.T. Spontaneous lipid peroxidation and production of hydrogen peroxide and superoxide in human spermatozoa. Superoxide dismutase as major enzyme protectant against oxygen toxicity. J. Androl. 8 1987 338
15. Lenzi A. Picardo M. Gandini L. Lombardo F. Terminali O. Passi S. Dondero F. Glutathione treatment of dyspermia: effect on the lipoperoxidation process. Hum. Reprod. 9 1994 2044
16. Weinberg J.B. Doty E. Bonaventura J. Haney A.F. Nitric oxide inhibition of human sperm motility. Fertil. Steril. 64 1995 408
17. Moncada S. Higgs A. The L-arginine-nitric oxide pathway. New Engl. J. Med. 329 1993 2002
18. Lowenstein C.J. Dinerman J.L. Snyder S.H. Nitric oxide: a physiologic messenger. Ann. Intern. Med. 120 1994 227
19. Beckman J.S. Crow J.P. Pathological implication of nitric oxide, superoxide and peroxynitrite formation. Biochem. Soc. Trans. 21 1993 330
20. Deliconstantinos G. Villiotou V. Stavrides J.C. Modulation of particulate nitric oxide synthase activity and peroxynitrite synthesis in cholesterol enriched endothelial cell membranes. Biochem. Pharmacol. 49 1995 1589
21. Deliconstantinos G. Villiotou V. Stavrides J.C. Release by ultraviolet B (u.v. B) radiation of nitric oxide (NO) from human keratinocytes: a potential role for nitric oxide in erythema production. Brit. J. Pharmacol. 114 1995 1257
22. Deliconstantinos G. Villiotou V. Stavrides J.C. Salemes N. Gogas J. Nitric oxide and peroxynitrite production by human erythrocytes: a causative factor of toxic anemia in breast cancer patients. Anticancer Res. 15 1995 1435
23. Arnelle D.R. Stamler J.S. NO+, NO, and NO- donation by S-nitrosothiols: implications for regulation of physiological function by S-nitrosylation and acceleration of disulfide formation. Arch. Biochem. Biophys. 318 1995 279
24. Whitehead T.P. Thorpe G.H.G. Enhanced chemiluminescent assay for antioxidant capacity in biological fluids. Anal. Chim. Acta 266 1992 265
25. Deliconstantinos G. Villiotou V. Stavrides J.C. Scavenging effects of hemoglobin and related heme containing compounds on nitric oxide, reactive oxidants and carcinogenic volatile nitrosocompounds of cigarette smoker. A new method for protein against the dangerous cigarette constituents Anticancer Res. 14 1995 2717
26. Schmidt H.H. Walter U. NO at work. Cell 78 1994 919
27. Griffith O.W. Stuehr D.J. Nitric oxide synthases: properties and catalytic mechanism. Ann. Rev. Physiol. 57 1995 707
28. Gross S.S. Wolin M.S. Nitric oxide: pathophysiological mechanisms. Ann. Rev. Physiol. 57 1995 737
29. Ischiropoulos H. Zhu L. Chen Z. Tsai M. Martin J.C. Smith C.D. Beckman J.S. Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase. Arch. Biochem. Biophys. 298 1992 431
30. van der Vliet A. Eiserich J.P. O'Neill C.A. Halliwell B. Cross C.E. Tyrosine modification by reactive nitrogen species: a closer look. Arch. Biochem. Biophys. 319 1995 341
31. Hille R. Nishino T. Flavoprotein structure and mechanism. 4. Xanthine oxidase and xanthine dehydrogenase FASEB J. 9 1995 995
32. Kanner J. Harel S. Granit R. Nitric oxide as an antioxidant. Arch. Biochem. Biophys. 289 1991 130
33. Beckman J.S. Ischiropoulos H. Zhu L. van der Woerd M. Smith C.D. Chen J. Harrison J. Martin J.C. Tsai M. Kinetics of superoxide dismutase- and iron-catalyzed nitration of phenolics by peroxynitrite. Arch. Biochem. Biophys. 298 1992 438
34. Hebbel R.P. Beyond haemoglobin polymerization: the red blood cell membrane and sickle disease physiology. Blood 77 1991 214
35. de Lamirande E. Gagnon C. Reactive oxygen species and human spermatozoa. II. Depletion of adenosine triphosphate plays an important role in the inhibition of sperm motility J. Androl. 13 1992 379