Neuroprotective effect of WIN 55,212-2 pretreatment against focal cerebral ischemia through activation of extracellular signal-regulated kinases in rats

European Journal of Pharmacology

Volumn 645, Issue 1-3, 2010, Pages 102-107

  Hu, Bo ^a   Wang, Qiang ^a   Chen, Ye ^a   Du, Juan ^a   Zhu, Xiaoling ^a   Lu, Yan ^a   Xiong, Lize ^a   Chen, Shaoyang ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Brain; Ischemia; Neuroprotection; Pretreatment; WIN 55,212 2

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TREATMENT DURATION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; BENZOXAZINES; BRAIN; BUTADIENES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; INFARCTION, MIDDLE CEREBRAL ARTERY; ISCHEMIC ATTACK, TRANSIENT; MALE; MORPHOLINES; NAPHTHALENES; NEUROPROTECTIVE AGENTS; NITRILES; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CANNABINOID; TIME FACTORS; UP-REGULATION;

EID: 77956188895     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.07.024     Document Type: Article

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