PiRNA-mediated silencing in Drosophila germlines

Seminars in Cell and Developmental Biology

Volumn 21, Issue 7, 2010, Pages 754-759

  Siomi, Mikiko C ^a,b   Miyoshi, Tomohiro ^a   Siomi, Haruhiko ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Drosophila; Germline; PiRNA; PIWI; RNA silencing

Indexed keywords

ARGONAUTE PROTEIN; PIWI INTERACTING RNA; PIWI PROTEIN;

DROSOPHILA; FERTILITY; GAMETOGENESIS; GENE EXPRESSION REGULATION; GENE SILENCING; GENOME; GERM LINE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PROCESSING; REVIEW; TRANSPOSON;

SOLANUM MELONGENA;

EID: 77956172367     PISSN: 10849521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.semcdb.2010.01.011     Document Type: Review

References (58)

1. Siomi H., Siomi M.C. On the road to reading the RNA-interference code. Nature 2009, 457:396-404.
2. Okamura K., Lai E.C. Endogenous small interfering RNAs in animals. Nat Rev Mol Cell Biol 2008, 9:673-678.
3. Ghildiyal M., Zamore P.D. Small silencing RNAs: an expanding universe. Nat Rev Genet 2009, 10:94-108.
4. Kim V.N., Han J., Siomi M.C. Biogenesis of small RNAs in animals. Nat Rev Mol Cell Biol 2009, 10:126-139.
5. Hutvagner G., Simard M.J. Argonaute proteins: key players in RNA silencing. Nat Rev Mol Cell Biol 2008, 9:22-32.
6. Wang Y., Sheng G., Juranek S., Tuschl T., Patel D.J. Structure of the guide-strand-containing argonaute silencing complex. Nature 2008, 456:209-213.
7. Wang Y., Juranek S., Li H., Sheng G., Tuschl T., Patel D.J. Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex. Nature 2008, 456:921-926.
8. Czech B., Malone C.D., Zhou R., Stark A., Schlingeheyde C., Dus M., et al. An endogenous small interfering RNA pathway in Drosophila. Nature 2008, 453:798-802.
9. Kawamura Y., Saito K., Kin T., Ono Y., Asai K., Sunohara T., et al. Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells. Nature 2008, 453:793-797.
10. Ghildiyal M., Seitz H., Horwich M.D., Li C., Du T., Lee S., et al. Endogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells. Science 2008, 320:1077-1081.
11. Förstemann K., Horwich M.D., Wee L., Tomari Y., Zamore P.D. Drosophila microRNAs are sorted into functionally distinct argonaute complexes after production by dicer-1. Cell 2007, 130:287-297.
12. Okamura K., Liu N., Lai E.C. Distinct mechanisms for microRNA strand selection by Drosophila Argonautes. Mol Cell 2009, 36:431-444.
13. Czech B., Zhou R., Erlich Y., Brennecke J., Binari R., Villalta C., et al. Hierarchical rules for Argonaute loading in Drosophila. Mol Cell 2009, 36:445-456.
14. Saito K., Nishida K.M., Mori T., Kawamura Y., Miyoshi K., Nagami T., et al. Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome. Genes Dev 2006, 20:2214-2222.
15. Brennecke J., Aravin A.A., Stark A., Dus M., Kellis M., Sachidanandam R., et al. Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila. Cell 2007, 128:1089-1103.
16. Gunawardane L.S., Saito K., Nishida K.M., Miyoshi K., Kawamura Y., Nagami T., et al. A slicer-mediated mechanism for repeat-associated siRNA 5' end formation in Drosophila. Science 2007, 315:1587-1590.
17. Yin H., Lin H. An epigenetic activation role of Piwi and a Piwi-associated piRNA in Drosophila melanogaster. Nature 2007, 450:304-308.
18. Nishida K.M., Saito K., Mori T., Kawamura Y., Nagami-Okada T., Inagaki S., et al. Gene silencing mechanisms mediated by Aubergine piRNA complexes in Drosophila male gonad. RNA 2007, 13:1911-1922.
19. Okamura K., Chung W.J., Ruby J.G., Guo H., Bartel D.P., Lai E.C. The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs. Nature 2008, 453:803-806.
20. Hartig J.V., Esslinger S., Böttcher R., Saito K., Förstemann K. Endo-siRNAs depend on a new isoform of loquacious and target artificially introduced, high-copy sequences. EMBO J 2009, 28:2932-2944.
21. Zhou R., Czech B., Brennecke J., Sachidanandam R., Wohlschlegel J.A., Perrimon N., et al. Processing of Drosophila endo-siRNAs depends on a specific Loquacious isoform. RNA 2009, 15:1886-1895.
22. Miyoshi K, Miyoshi T, Hartig JV, Siomi H, Siomi MC. Molecular mechanisms that funnel RNA precursors into endogenous small-interfering RNA and micro RNA biogenesis pathways in Drosophila. RNA, 2010, doi:10.1261/rna.1952110.
23. Bernstein E., Caudy A.A., Hammond S.M., Hannon G.J. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 2001, 409:363-366.
24. Liu Q., Rand T.A., Kalidas S., Du F., Kim H.E., Smith D.P., et al. R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway. Science 2003, 301:1921-1925.
25. Marques J.T., Kim K., Wu P.H., Alleyne T.M., Jafari N., Carthew R.W. Loqs and R2D2 act sequentially in the siRNA pathway in Drosophila. Nat Struct Mol Biol 2009, 1.
26. Förstemann K., Tomari Y., Du T., Vagin V.V., Denli A.M., Bratu D.P., et al. Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein. PLoS Biol 2005, 3:e236.
27. Saito K., Ishizuka A., Siomi H., Siomi M.C. Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells. PLoS Biol 2005, 3:e235.
28. Vagin V.V., Sigova A., Li C., Seitz H., Gvozdev V., Zamore P.D. A distinct small RNA pathway silences selfish genetic elements in the germline. Science 2006, 313:320-324.
29. Lin H., Spradling A.C. A novel group of pumilio mutations affects the asymmetric division of germline stem cells in the Drosophila ovary. Development 1997, 124:2463-2476.
30. Schüpbach T., Wieschaus E. Female sterile mutations on the second chromosome of Drosophila melanogaster. II. Mutations blocking oogenesis or altering egg morphology. Genetics 1991, 129:1119-1136.
31. Deshpande G., Calhoun G., Schedl P. Drosophila argonaute-2 is required early in embryogenesis for the assembly of centric/centromeric heterochromatin, nuclear division, nuclear migration, and germ-cell formation. Genes Dev 2005, 19:1680-1685.
32. Klattenhoff C., Xi H., Li C., Lee S., Xu J., Khurana J.S., et al. The Drosophila HP1 homolog Rhino is required for transposon silencing and piRNA production by dual-strand clusters. Cell 2009, 138:1137-1149.
33. Sarot E., Payen-Groschêne G., Bucheton A., Pélisson A. Evidence for a piwi-dependent RNA silencing of the gypsy endogenous retrovirus by the Drosophila melanogaster flamenco gene. Genetics 2004, 166:1313-1321.
34. Pélisson A., Song S.U., Prud'homme N., Smith P.A., Bucheton A., Corces V.G. Gypsy transposition correlates with the production of a retroviral envelope-like protein under the tissue-specific control of the Drosophila flamenco gene. EMBO J 1994, 13:4401-4411.
35. Lau N.C., Robine N., Martin R., Chung W.J., Niki Y., Berezikov E., et al. Abundant primary piRNAs, endo-siRNAs, and microRNAs in a Drosophila ovary cell line. Genome Res 2009, 19:1776-1785.
36. Li C., Vagin V.V., Lee S., Xu J., Ma S., Xi H., et al. Collapse of germline piRNAs in the absence of Argonaute3 reveals somatic piRNAs in flies. Cell 2009, 137:509-521.
37. Malone C.D., Brennecke J., Dus M., Stark A., McCombie W.R., Sachidanandam R., et al. Specialized piRNA pathways act in germline and somatic tissues of the Drosophila ovary. Cell 2009, 137:522-535.
38. Saito K., Inagaki S., Mituyama T., Kawamura Y., Ono Y., Sakota E., et al. A regulatory circuit for piwi by the large Maf gene traffic jam in Drosophila. Nature 2009, 461:1296-1299.
39. Niki Y., Yamaguchi T., Mahowald A.P. Establishment of stable cell lines of Drosophila germ-line stem cells. Proc Natl Acad Sci USA 2006, 103:16325-16330.
40. Saito K., Sakaguchi Y., Suzuki T., Suzuki T., Siomi H., Siomi M.C. Pimet, the Drosophila homolog of HEN1, mediates 2'-O-methylation of Piwi-interacting RNAs at their 3' ends. Genes Dev 2007, 21:1603-1608.
41. Horwich M.D., Li C., Matranga C., Vagin V., Farley G., Wang P., et al. The Drosophila RNA methyltransferase, DmHen1, modifies germline piRNAs and single-stranded siRNAs in RISC. Curr Biol 2007, 17:1265-1272.
42. Yu B., Yang Z., Li J., Minakhina S., Yang M., Padgett R.W., et al. Methylation as a crucial step in plant microRNA biogenesis. Science 2005, 307:932-935.
43. Chen X. MicroRNA biogenesis and function in plants. FEBS Lett 2005, 579:5923-5931.
44. Li J., Yang Z., Yu B., Liu J., Chen X. Methylation protects miRNAs and siRNAs from a 3'-end uridylation activity in Arabidopsis. Curr Biol 2005, 15:1501-1507.
45. Li M.A., Alls J.D., Avancini R.M., Koo K., Godt D. The large Maf factor Traffic Jam controls gonad morphogenesis in Drosophila. Nat Cell Biol 2003, 5:994-1000.
46. Szakmary A., Reedy M., Qi H., Lin H. The Yb protein defines a novel organelle and regulates male germline stem cell self-renewal in Drosophila melanogaster. J Cell Biol 2009, 185:613-627.
47. Kirino Y., Kim N., de Planell-Saguer M., Khandros E., Chiorean S., Klein P.S., et al. Arginine methylation of Piwi proteins catalysed by dPRMT5 is required for Ago3 and Aub stability. Nat Cell Biol 2009, 11:652-658.
48. Nishida K.M., Okada T.N., Kawamura T., Mituyama T., Kawamura Y., Inagaki S., et al. Functional involvement of Tudor and dPRMT5 in the piRNA processing pathway in Drosophila germlines. EMBO J 2009, 28:3820-3831.
49. Meister G., Eggert C., Fischer U. SMN-mediated assembly of RNPs: a complex story. Trends Cell Biol 2002, 12:472-478.
50. Battle D.J., Kasim M., Yong J., Lotti F., Lau C.K., Mouaikel J., et al. The SMN complex: an assembly machine for RNPs. Cold Spring Harb Symp Quant Biol 2006, 71:313-320.
51. Bozzetti M.P., Massari S., Finelli P., Meggio F., Pinna L.A., Boldyreff B., et al. The Ste locus, a component of the parasitic cry-Ste system of Drosophila melanogaster, encodes a protein that forms crystals in primary spermatocytes and mimics properties of the beta subunit of casein kinase 2. Proc Natl Acad Sci USA 1995, 92:6067-6071.
52. Palumbo G., Bonaccorsi S., Robbins L.G., Pimpinelli S. Genetic analysis of Stellate elements of Drosophila melanogaster. Genetics 1994, 138:1181-1197.
53. Aravin A.A., Naumova N.M., Tulin A.V., Vagin V.V., Rozovsky Y.M., Gvozdev V.A. Double-stranded RNA-mediated silencing of genomic tandem repeats and transposable elements in the D. melanogaster germline. Curr Biol 2001, 11:1017-1027.
54. Lasko P.F., Ashburner M. The product of the Drosophila gene vasa is very similar to eukaryotic initiation factor-4. Nature 1988, 335:611-617.
55. Styhler S., Nakamura A., Swan A., Suter B., Lasko P. vasa is required for GURKEN accumulation in the oocyte, and is involved in oocyte differentiation and germline cyst development. Development 1998, 125:1569-1578.
56. Robine N., Lau N.C., Balla S., Jin Z., Okamura K., Kuramochi-Miyagawa S., et al. A broadly conserved pathway generates 3'UTR-directed primary piRNAs. Curr Biol 2009.
57. Snow P.M., Bieber A.J., Goodman C.S. Fasciclin III: a novel homophilic adhesion molecule in Drosophila. Cell 1989, 59:313-323.
58. Cox D.N., Chao A., Baker J., Chang L., Qiao D., Lin H. A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal. Genes Dev 1998, 12:3715-3727.